Large-Conductance Calcium-Activated Potassium Channel alpha Subunits
"Large-Conductance Calcium-Activated Potassium Channel alpha Subunits" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The pore-forming subunits of large-conductance calcium-activated potassium channels. They form tetramers in CELL MEMBRANES.
| Descriptor ID |
D051037
|
| MeSH Number(s) |
D12.776.157.530.400.600.150.500.500 D12.776.543.550.450.750.150.500.500 D12.776.543.585.400.750.150.500.249
|
| Concept/Terms |
Large-Conductance Calcium-Activated Potassium Channel alpha Subunits- Large-Conductance Calcium-Activated Potassium Channel alpha Subunits
- Large Conductance Calcium Activated Potassium Channel alpha Subunits
- Large-Conductance Calcium-Activated Potassium Channels, alpha Subunit
- Large Conductance Calcium Activated Potassium Channels, alpha Subunit
- MaxiK Channel alpha Subunit
|
Below are MeSH descriptors whose meaning is more general than "Large-Conductance Calcium-Activated Potassium Channel alpha Subunits".
Below are MeSH descriptors whose meaning is more specific than "Large-Conductance Calcium-Activated Potassium Channel alpha Subunits".
This graph shows the total number of publications written about "Large-Conductance Calcium-Activated Potassium Channel alpha Subunits" by people in this website by year, and whether "Large-Conductance Calcium-Activated Potassium Channel alpha Subunits" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Large-Conductance Calcium-Activated Potassium Channel alpha Subunits" by people in Profiles.
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KCa1.1 and Kv1.3 channels regulate the interactions between fibroblast-like synoviocytes and T lymphocytes during rheumatoid arthritis. Arthritis Res Ther. 2019 01 07; 21(1):6.
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Targeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid Arthritis. J Pharmacol Exp Ther. 2018 05; 365(2):227-236.
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KCa1.1 channels as therapeutic targets for rheumatoid arthritis. Expert Opin Ther Targets. 2017 12; 21(12):1077-1081.
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KCa1.1 channels regulate ?1-integrin function and cell adhesion in rheumatoid arthritis fibroblast-like synoviocytes. FASEB J. 2017 08; 31(8):3309-3320.
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Functional KCa1.1 channels are crucial for regulating the proliferation, migration and differentiation of human primary skeletal myoblasts. Cell Death Dis. 2016 10 20; 7(10):e2426.
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Different expression of ? subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes. Arthritis Res Ther. 2016 05 10; 18(1):103.
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KCa1.1 inhibition attenuates fibroblast-like synoviocyte invasiveness and ameliorates disease in rat models of rheumatoid arthritis. Arthritis Rheumatol. 2015 Jan; 67(1):96-106.
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Role of TRPC1 and TRPC3 channels in contraction and relaxation of mouse thoracic aorta. J Vasc Res. 2013; 50(1):11-20.
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KCa1.1 potassium channels regulate key proinflammatory and invasive properties of fibroblast-like synoviocytes in rheumatoid arthritis. J Biol Chem. 2012 Feb 03; 287(6):4014-22.
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Comparative effects of H+ and Ca2+ on large-conductance Ca2+- and voltage-gated Slo1 K+ channels. Channels (Austin). 2009 Jul-Aug; 3(4):249-58.