"CDC2-CDC28 Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of cell cycle-dependent kinases that are related in structure to CDC28 PROTEIN KINASE; S CEREVISIAE; and the CDC2 PROTEIN KINASE found in mammalian species.
| Descriptor ID |
D042846
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.646.500.500 D12.644.360.250.067 D12.776.167.200.067 D12.776.476.250.067
|
| Concept/Terms |
CDC2-CDC28 Kinases- CDC2-CDC28 Kinases
- CDC2 CDC28 Kinases
- CDC2+-CDC28-related Protein Kinase
- CDC2+ CDC28 related Protein Kinase
|
Below are MeSH descriptors whose meaning is more general than "CDC2-CDC28 Kinases".
Below are MeSH descriptors whose meaning is more specific than "CDC2-CDC28 Kinases".
This graph shows the total number of publications written about "CDC2-CDC28 Kinases" by people in this website by year, and whether "CDC2-CDC28 Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 |
| 1998 | 1 | 0 | 1 |
| 1999 | 2 | 0 | 2 |
| 2000 | 3 | 0 | 3 |
| 2001 | 2 | 0 | 2 |
| 2002 | 2 | 0 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 2 | 3 |
| 2005 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "CDC2-CDC28 Kinases" by people in Profiles.
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Differential expression of CKS-1B in typical and blastoid variants of mantle cell lymphoma. Hum Pathol. 2010 Oct; 41(10):1448-55.
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Aberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death. Int J Cancer. 2008 Aug 01; 123(3):543-51.
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HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition. Mol Cell Biol. 2005 Jul; 25(14):6140-53.
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A role for PML3 in centrosome duplication and genome stability. Mol Cell. 2005 Mar 04; 17(5):721-32.
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The low molecular weight cyclin E isoforms augment angiogenesis and metastasis of human melanoma cells in vivo. Cancer Res. 2005 Feb 01; 65(3):692-7.
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Cyclin-dependent kinase activity is required for progesterone receptor function: novel role for cyclin A/Cdk2 as a progesterone receptor coactivator. Mol Cell Biol. 2005 Jan; 25(1):264-77.
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Phosphorylation of progesterone receptor serine 400 mediates ligand-independent transcriptional activity in response to activation of cyclin-dependent protein kinase 2. Mol Cell Biol. 2004 Dec; 24(24):10542-57.
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Cyclic mechanical strain inhibits skeletal myogenesis through activation of focal adhesion kinase, Rac-1 GTPase, and NF-kappaB transcription factor. FASEB J. 2004 Oct; 18(13):1524-35.
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Cyclin-dependent kinases regulate the antiproliferative function of Smads. Nature. 2004 Jul 08; 430(6996):226-31.
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Antitumor activity of IFIX, a novel interferon-inducible HIN-200 gene, in breast cancer. Oncogene. 2004 Jun 03; 23(26):4556-66.