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Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth.
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Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth.
Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth. Nature. 2015 Nov 05; 527(7576):100-104.
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PubMed
subject areas
Adaptation, Physiological
Animals
Astrocytes
Brain
Brain Neoplasms
Calcium-Binding Proteins
Cell Proliferation
Chemokine CCL2
DNA-Binding Proteins
Down-Regulation
Evolution, Molecular
Exosomes
Female
Gene Expression Regulation, Neoplastic
Gene Silencing
Genes, Tumor Suppressor
Humans
Male
Mice
Microfilament Proteins
MicroRNAs
PTEN Phosphohydrolase
RNA, Messenger
Tumor Microenvironment
Tumor Suppressor Proteins
authors with profiles
AYSEGUL A SAHIN
JOSEPH MCCARTY
CHENYU ZHANG
JUN YAO
SUYUN HUANG