"Chemokine CCL2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.
| Descriptor ID |
D018932
|
| MeSH Number(s) |
D12.644.276.374.200.110.990.600 D12.776.467.374.200.110.990.600 D23.125.300.110.990.600 D23.469.200.110.990.600 D23.529.374.200.110.990.500
|
| Concept/Terms |
Chemokine CCL2- Chemokine CCL2
- CCL2, Chemokine
- Monocyte Chemotactic and Activating Factor
- Monocyte Chemoattractant Protein-1
- Chemoattractant Protein-1, Monocyte
- Monocyte Chemoattractant Protein 1
- Chemokines CCL2
- CCL2, Chemokines
- CCL2 Chemokine
- Chemokine, CCL2
- Chemokine (C-C Motif) Ligand 2
- Monocyte Chemotactic Protein-1
- Chemotactic Protein-1, Monocyte
- Monocyte Chemotactic Protein 1
|
Below are MeSH descriptors whose meaning is more general than "Chemokine CCL2".
Below are MeSH descriptors whose meaning is more specific than "Chemokine CCL2".
This graph shows the total number of publications written about "Chemokine CCL2" by people in this website by year, and whether "Chemokine CCL2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 4 | 1 | 5 |
| 2005 | 1 | 3 | 4 |
| 2006 | 0 | 1 | 1 |
| 2007 | 5 | 1 | 6 |
| 2008 | 1 | 2 | 3 |
| 2009 | 2 | 5 | 7 |
| 2010 | 1 | 5 | 6 |
| 2011 | 0 | 7 | 7 |
| 2012 | 2 | 4 | 6 |
| 2013 | 1 | 3 | 4 |
| 2014 | 1 | 2 | 3 |
| 2015 | 2 | 2 | 4 |
| 2016 | 2 | 1 | 3 |
| 2017 | 1 | 3 | 4 |
| 2018 | 1 | 2 | 3 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
| 2025 | 0 | 2 | 2 |
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Below are the most recent publications written about "Chemokine CCL2" by people in Profiles.
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Targeting STING to disrupt macrophage-mediated adhesion in encapsulating peritoneal sclerosis. Commun Biol. 2025 Aug 23; 8(1):1266.
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Characterization of hepatic pathology during azoxymethane-induced acute liver failure. World J Gastroenterol. 2025 Mar 28; 31(12):103952.
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Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a CCL2-CCR2 pathway and NO dysregulation. Cell Rep. 2024 05 28; 43(5):114193.
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Association of Circulating Monocyte Chemoattractant Protein-1 Levels With Cardiovascular Mortality: A Meta-analysis of Population-Based Studies. JAMA Cardiol. 2021 05 01; 6(5):587-592.
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Aspirin Modifies Inflammatory Mediators and Metabolomic Profiles and Contributes to the Suppression of Obesity-Associated Breast Cancer Cell Growth. Int J Mol Sci. 2020 Jun 30; 21(13).
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Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17?180 Individuals. Circ Res. 2019 09 27; 125(8):773-782.
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CCR2 Chemokine Receptors Enhance Growth and Cell-Cycle Progression of Breast Cancer Cells through SRC and PKC Activation. Mol Cancer Res. 2019 02; 17(2):604-617.
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Association of Monocyte Chemoattractant Protein-1 with Death and Atherosclerotic Events in Chronic Kidney Disease. Am J Nephrol. 2018; 47(6):395-405.
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A prospective study of soluble receptor for advanced glycation end products and adipokines in association with pancreatic cancer in postmenopausal women. Cancer Med. 2018 05; 7(5):2180-2191.
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CCL2 in the Circulation Predicts Long-Term Progression of Interstitial Lung Disease in Patients With Early Systemic Sclerosis: Data From Two Independent Cohorts. Arthritis Rheumatol. 2017 09; 69(9):1871-1878.