"Chemokine CCL2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.
| Descriptor ID |
D018932
|
| MeSH Number(s) |
D12.644.276.374.200.110.990.600 D12.776.467.374.200.110.990.600 D23.125.300.110.990.600 D23.469.200.110.990.600 D23.529.374.200.110.990.500
|
| Concept/Terms |
Chemokine CCL2- Chemokine CCL2
- CCL2, Chemokine
- Monocyte Chemotactic and Activating Factor
- Monocyte Chemoattractant Protein-1
- Chemoattractant Protein-1, Monocyte
- Monocyte Chemoattractant Protein 1
- Chemokines CCL2
- CCL2, Chemokines
- CCL2 Chemokine
- Chemokine, CCL2
- Chemokine (C-C Motif) Ligand 2
- Monocyte Chemotactic Protein-1
- Chemotactic Protein-1, Monocyte
- Monocyte Chemotactic Protein 1
|
Below are MeSH descriptors whose meaning is more general than "Chemokine CCL2".
Below are MeSH descriptors whose meaning is more specific than "Chemokine CCL2".
This graph shows the total number of publications written about "Chemokine CCL2" by people in this website by year, and whether "Chemokine CCL2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1995 | 2 | 0 | 2 |
| 1996 | 1 | 0 | 1 |
| 1997 | 3 | 1 | 4 |
| 1998 | 1 | 1 | 2 |
| 2000 | 2 | 3 | 5 |
| 2001 | 2 | 2 | 4 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 3 | 4 |
| 2004 | 4 | 3 | 7 |
| 2005 | 5 | 3 | 8 |
| 2006 | 1 | 2 | 3 |
| 2007 | 5 | 2 | 7 |
| 2008 | 1 | 2 | 3 |
| 2009 | 4 | 6 | 10 |
| 2010 | 1 | 5 | 6 |
| 2011 | 0 | 5 | 5 |
| 2012 | 4 | 5 | 9 |
| 2013 | 3 | 5 | 8 |
| 2014 | 1 | 3 | 4 |
| 2015 | 3 | 1 | 4 |
| 2016 | 1 | 2 | 3 |
| 2017 | 2 | 4 | 6 |
| 2018 | 1 | 3 | 4 |
| 2019 | 3 | 2 | 5 |
| 2020 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Chemokine CCL2" by people in Profiles.
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Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a CCL2-CCR2 pathway and NO dysregulation. Cell Rep. 2024 May 28; 43(5):114193.
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Alleviating iatrogenic effects of paclitaxel via antiinflammatory treatment. Vasc Med. 2024 Aug; 29(4):369-380.
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Differential Gene Expression of fresh tissue and patient-derived explants' matricellular proteins augment inflammatory breast cancer metastasis: the possible role of IL-6 and MCP-1. QJM. 2023 May 27; 116(5):345-354.
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Disruption of SLFN11 Deficiency-Induced CCL2 Signaling and Macrophage M2 Polarization Potentiates Anti-PD-1 Therapy Efficacy in Hepatocellular Carcinoma. Gastroenterology. 2023 06; 164(7):1261-1278.
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Cellular microRNAs correlate with clinical parameters in multiple injury patients. J Trauma Acute Care Surg. 2022 10 01; 93(4):427-438.
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Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2. Stem Cell Reports. 2021 09 14; 16(9):2274-2288.
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IL-8 and MCP-1/CCL2 regulate proteolytic activity in triple negative inflammatory breast cancer a mechanism that might be modulated by Src and Erk1/2. Toxicol Appl Pharmacol. 2020 08 15; 401:115092.
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MCP-1/CCR-2 axis in adipocytes and cancer cell respectively facilitates ovarian cancer peritoneal metastasis. Oncogene. 2020 02; 39(8):1681-1695.
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Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17?180 Individuals. Circ Res. 2019 09 27; 125(8):773-782.
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The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression. Cancer Cell. 2019 08 12; 36(2):139-155.e10.