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Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds.
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Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds.
Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds. J Med Chem. 2015 Sep 10; 58(17):6899-6908.
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PubMed
subject areas
Antineoplastic Agents
Cell Line, Tumor
Cell Proliferation
Crystallography, X-Ray
Drug Screening Assays, Antitumor
Glutarates
Histones
Humans
Isocitrate Dehydrogenase
Kinetics
Methylation
Models, Molecular
Mutation
Neoplastic Stem Cells
Protein Binding
Protein Conformation
Structure-Activity Relationship
Thermodynamics
Thiohydantoins
authors with profiles
YONGCHENG SONG