TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pathology & Immunology
AddressOne Baylor Plaza
Houston, TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ku AF, Sharma KL, Ta HM, Sutton CM, Bohren KM, Wang Y, Chamakuri S, Chen R, Hakenjos JM, Jimmidi R, Kent K, Li F, Li JY, Ma L, Madasu C, Palaniappan M, Palmer SS, Qin X, Robers MB, Sankaran B, Tan Z, Vasquez YM, Wang J, Wilkinson J, Yu Z, Ye Q, Young DW, Teng M, Kim C, Matzuk MM. Reversible male contraception by targeted inhibition of serine/threonine kinase 33. Science. 2024 May 24; 384(6698):885-890. PMID: 38781365.
      Citations:    Fields:    Translation:HumansAnimals
    2. Madasu C, Liao Z, Parks SE, Sharma KL, Bohren KM, Ye Q, Li F, Palaniappan M, Tan Z, Yuan F, Creighton CJ, Tang S, Masand RP, Guan X, Young DW, Monsivais D, Matzuk MM. Identification of potent pan-ephrin receptor kinase inhibitors using DNA-encoded chemistry technology. Proc Natl Acad Sci U S A. 2024 May 07; 121(19):e2322934121. PMID: 38701119; PMCID: PMC11087803.
      Citations: 1     Fields:    Translation:Humans
    3. Judge A, Sankaran B, Hu L, Palaniappan M, Birgy A, Prasad BVV, Palzkill T. Network of epistatic interactions in an enzyme active site revealed by large-scale deep mutational scanning. Proc Natl Acad Sci U S A. 2024 Mar 19; 121(12):e2313513121. PMID: 38483989; PMCID: PMC10962969.
      Citations:    Fields:    Translation:Cells
    4. Palanisamy S, Rajan VK, Mani AK, Palaniappan M, Santulli C, Alavudeen A, Ayrilmis N. Extraction and characterization of fiber from the flower stalk of Sansevieria cylindrica. Physiol Plant. 2024 Mar-Apr; 176(2):e14279. PMID: 38629121.
      Citations:    Fields:    Translation:Animals
    5. Ma X, Botros A, Yun SR, Park EY, Kim O, Park S, Pham TH, Chen R, Palaniappan M, Matzuk MM, Kim J, Fern?ndez FM. Ultrahigh resolution lipid mass spectrometry imaging of high-grade serous ovarian cancer mouse models. Front Chem. 2023; 11:1332816. PMID: 38260043; PMCID: PMC10800477.
    6. Park S, Fan J, Chamakuri S, Palaniappan M, Sharma K, Qin X, Wang J, Tan Z, Judge A, Hu L, Sankaran B, Li F, Prasad BVV, Matzuk MM, Palzkill T. Exploiting the Carboxylate-Binding Pocket of ?-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library. J Med Chem. 2024 01 11; 67(1):620-642. PMID: 38117688.
      Citations:    Fields:    
    7. Ma X, Botros A, Yun SR, Park EY, Kim O, Chen R, Palaniappan M, Matzuk MM, Kim J, Fern?ndez FM. Ultrahigh Resolution Lipid Mass Spectrometry Imaging of High-Grade Serous Ovarian Cancer Mouse Models. bioRxiv. 2023 Nov 02. PMID: 37961688; PMCID: PMC10634942.
    8. Bifarin OO, Sah S, Gaul DA, Moore SG, Chen R, Palaniappan M, Kim J, Matzuk MM, Fern?ndez FM. Machine Learning Reveals Lipidome Remodeling Dynamics in a Mouse Model of Ovarian Cancer. J Proteome Res. 2023 06 02; 22(6):2092-2108. PMID: 37220064; PMCID: PMC10243112.
      Citations: 1     Fields:    Translation:HumansAnimals
    9. Gowri NV, Dwivedi JN, Krishnaveni K, Boopathi S, Palaniappan M, Medikondu NR. Experimental investigation and multi-objective optimization of eco-friendly near-dry electrical discharge machining of shape memory alloy using Cu/SiC/Gr composite electrode. Environ Sci Pollut Res Int. 2023 Oct; 30(49):107498-107516. PMID: 37126160.
      Citations:    Fields:    
    10. Modukuri RK, Monsivais D, Li F, Palaniappan M, Bohren KM, Tan Z, Ku AF, Wang Y, Madasu C, Li JY, Tang S, Miklossy G, Palmer SS, Young DW, Matzuk MM. Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening. J Med Chem. 2023 02 09; 66(3):2143-2160. PMID: 36719862; PMCID: PMC9924264.
      Citations: 2     Fields:    Translation:HumansCells
    11. Bifarin OO, Sah S, Gaul DA, Moore SG, Chen R, Palaniappan M, Kim J, Matzuk MM, Fern?ndez FM. Machine Learning Reveals Lipidome Remodeling Dynamics in a Mouse Model of Ovarian Cancer. bioRxiv. 2023 Jan 04. PMID: 36711577; PMCID: PMC9881992.
    12. Lu S, Hu L, Lin H, Judge A, Rivera P, Palaniappan M, Sankaran B, Wang J, Prasad BVV, Palzkill T. An active site loop toggles between conformations to control antibiotic hydrolysis and inhibition potency for CTX-M ?-lactamase drug-resistance enzymes. Nat Commun. 2022 11 07; 13(1):6726. PMID: 36344533; PMCID: PMC9640584.
      Citations: 1     Fields:    Translation:Cells
    13. Ye Q, Belabed H, Wang Y, Yu Z, Palaniappan M, Li JY, Kalovidouris SA, MacKenzie KR, Teng M, Young DW, Fujihara Y, Matzuk MM. Advancing ASMS with LC-MS/MS for the discovery of novel PDCL2 ligands from DNA-encoded chemical library selections. Andrology. 2023 07; 11(5):808-815. PMID: 36209044.
      Citations:    Fields:    Translation:HumansAnimals
    14. Karuppiah G, Kuttalam KC, Palaniappan M, Palanisamy S, Santulli C. Multiobjective Optimization of Fabrication Parameters of Jute Fiber/Polyester Composites with Egg Shell Powder and Nanoclay Filler. Molecules. 2020 Nov 27; 25(23). PMID: 33261104; PMCID: PMC7730131.
      Citations:    Fields:    Translation:AnimalsCells
    15. Taylor DM, Anglin J, Park S, Ucisik MN, Faver JC, Simmons N, Jin Z, Palaniappan M, Nyshadham P, Li F, Campbell J, Hu L, Sankaran B, Prasad BVV, Huang H, Matzuk MM, Palzkill T. Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries. ACS Infect Dis. 2020 05 08; 6(5):1214-1227. PMID: 32182432; PMCID: PMC7673237.
      Citations: 10     Fields:    Translation:Cells
    16. Monty OBC, Nyshadham P, Bohren KM, Palaniappan M, Matzuk MM, Young DW, Simmons N. Homogeneous and Functional Group Tolerant Ring-Closing Metathesis for DNA-Encoded Chemical Libraries. ACS Comb Sci. 2020 02 10; 22(2):80-88. PMID: 31913011; PMCID: PMC7014401.
      Citations: 7     Fields:    Translation:Cells
    17. Palaniappan M, Nguyen L, Grimm SL, Xi Y, Xia Z, Li W, Coarfa C. The genomic landscape of estrogen receptor a binding sites in mouse mammary gland. PLoS One. 2019; 14(8):e0220311. PMID: 31408468; PMCID: PMC6692022.
      Citations: 10     Fields:    Translation:AnimalsCells
    18. Li JY, Miklossy G, Modukuri RK, Bohren KM, Yu Z, Palaniappan M, Faver JC, Riehle K, Matzuk MM, Simmons N. Palladium-Catalyzed Hydroxycarbonylation of (Hetero)aryl Halides for DNA-Encoded Chemical Library Synthesis. Bioconjug Chem. 2019 08 21; 30(8):2209-2215. PMID: 31329429; PMCID: PMC6706801.
      Citations: 5     Fields:    Translation:Cells
    19. Du HC, Simmons N, Faver JC, Yu Z, Palaniappan M, Riehle K, Matzuk MM. A Mild, DNA-Compatible Nitro Reduction Using B2(OH)4. Org Lett. 2019 04 05; 21(7):2194-2199. PMID: 30860855; PMCID: PMC6457042.
      Citations: 14     Fields:    Translation:Cells
    20. Palaniappan M, Edwards D, Creighton CJ, Medina D, Conneely OM. Reprogramming of the estrogen responsive transcriptome contributes to tamoxifen-dependent protection against tumorigenesis in the p53 null mammary epithelial cells. PLoS One. 2018; 13(3):e0194913. PMID: 29590203; PMCID: PMC5874056.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    21. Palaniappan M, Menon B, Menon KM. Stimulatory effect of insulin on theca-interstitial cell proliferation and cell cycle regulatory proteins through MTORC1 dependent pathway. Mol Cell Endocrinol. 2013 Feb 05; 366(1):81-9. PMID: 23261705; PMCID: PMC3552006.
      Citations: 12     Fields:    Translation:AnimalsCells
    22. Palaniappan M, Menon KM. Luteinizing hormone/human chorionic gonadotropin-mediated activation of mTORC1 signaling is required for androgen synthesis by theca-interstitial cells. Mol Endocrinol. 2012 Oct; 26(10):1732-42. PMID: 22827930; PMCID: PMC3458224.
      Citations: 13     Fields:    Translation:AnimalsCells
    23. Will MA, Palaniappan M, Peegel H, Kayampilly P, Menon KM. Metformin: direct inhibition of rat ovarian theca-interstitial cell proliferation. Fertil Steril. 2012 Jul; 98(1):207-14. PMID: 22608319; PMCID: PMC3389190.
      Citations: 8     Fields:    Translation:AnimalsCells
    24. Palaniappan M, Menon KM. Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of AKT/mTORC1 signaling pathway. Mol Endocrinol. 2010 Sep; 24(9):1782-93. PMID: 20660299; PMCID: PMC2940479.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    25. Palaniappan M, Menon KM. Regulation of sterol regulatory element-binding transcription factor 1a by human chorionic gonadotropin and insulin in cultured rat theca-interstitial cells. Biol Reprod. 2009 Aug; 81(2):284-92. PMID: 19299314; PMCID: PMC2849815.
      Citations: 7     Fields:    Translation:AnimalsCells
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