TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    R29CA077530     (LYDON, JOHN P)Apr 1, 1998 - Mar 31, 2005
    Role: Principal Investigator

    R01CA077530     (LYDON, JOHN P)Apr 1, 1998 - Apr 30, 2010
    Role: Principal Investigator

    R01HD042311     (LYDON, JOHN P)Apr 1, 2002 - Jul 31, 2024
    Molecular Analysis of Uterine Receptivity
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. McGlade EA, Herrera GG, Stephens KK, Olsen SLW, Winuthayanon S, Guner J, Hewitt SC, Korach KS, DeMayo FJ, Lydon JP, Monsivais D, Winuthayanon W. Cell-type specific analysis of physiological action of estrogen in mouse oviducts. FASEB J. 2021 05; 35(5):e21563. PMID: 33818810.
      Citations:    Fields:    
    2. Wang X, Praça MSL, Wendel JRH, Emerson RE, DeMayo FJ, Lydon JP, Hawkins SM. Vaginal Squamous Cell Carcinoma Develops in Mice with Conditional Arid1a Loss and Gain of Oncogenic Kras Driven by Progesterone Receptor Cre. Am J Pathol. 2021 07; 191(7):1281-1291. PMID: 33882289.
      Citations:    Fields:    
    3. Maurya VK, DeMayo FJ, Lydon JP. Illuminating the "Black Box" of Progesterone-Dependent Embryo Implantation Using Engineered Mice. Front Cell Dev Biol. 2021; 9:640907. PMID: 33898429.
    4. Peavey MC, Wu SP, Li R, Liu J, Emery OM, Wang T, Zhou L, Wetendorf M, Yallampalli C, Gibbons WE, Lydon JP, DeMayo FJ. Progesterone receptor isoform B regulates the Oxtr-Plcl2-Trpc3 pathway to suppress uterine contractility. Proc Natl Acad Sci U S A. 2021 Mar 16; 118(11). PMID: 33707208.
      Citations:    Fields:    
    5. Kim YS, Yang SC, Park M, Choi Y, DeMayo FJ, Lydon JP, Kim HR, Lim HJ, Song H. Different Cre systems induce differential microRNA landscapes and abnormalities in the female reproductive tracts of Dgcr8 conditional knockout mice. Cell Prolif. 2021 Mar; 54(3):e12996. PMID: 33496365.
      Citations: 1     Fields:    Translation:Animals
    6. Kim O, Park EY, Kwon SY, Shin S, Emerson RE, Shin YH, DeMayo FJ, Lydon JP, Coffey DM, Hawkins SM, Quilliam LA, Cheon DJ, Fernández FM, Nephew KP, Karpf AR, Widschwendter M, Sood AK, Bast RC, Godwin AK, Miller KD, Cho CH, Kim J. Targeting progesterone signaling prevents metastatic ovarian cancer. Proc Natl Acad Sci U S A. 2020 12 15; 117(50):31993-32004. PMID: 33262282.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    7. Fang X, Ni N, Gao Y, Lydon JP, Ivanov I, Rijnkels M, Bayless KJ, Li Q. Transforming growth factor beta signaling and decidual integrity in mice†. Biol Reprod. 2020 12 01; 103(6):1186-1198. PMID: 32902612.
      Citations: 1     Fields:    
    8. Chi RA, Wang T, Huang CL, Wu SP, Young SL, Lydon JP, DeMayo FJ. WNK1 regulates uterine homeostasis and its ability to support pregnancy. JCI Insight. 2020 11 19; 5(22). PMID: 33048843.
      Citations:    Fields:    Translation:HumansAnimalsCells
    9. Li R, Wu SP, Zhou L, Nicol B, Lydon JP, Yao HH, DeMayo FJ. Increased FOXL2 expression alters uterine structures and functions†. Biol Reprod. 2020 10 29; 103(5):951-965. PMID: 32948877.
      Citations: 1     Fields:    
    10. Wetendorf M, Li R, Wu SP, Liu J, Creighton CJ, Wang T, Janardhan KS, Willson CJ, Lanz RB, Murphy BD, Lydon JP, DeMayo FJ. Constitutive expression of progesterone receptor isoforms promotes the development of hormone-dependent ovarian neoplasms. Sci Signal. 2020 10 06; 13(652). PMID: 33023986.
      Citations:    Fields:    
    11. Wang X, Wendel JRH, Emerson RE, Broaddus RR, Creighton CJ, Rusch DB, Buechlein A, DeMayo FJ, Lydon JP, Hawkins SM. Pten and Dicer1 loss in the mouse uterus causes poorly differentiated endometrial adenocarcinoma. Oncogene. 2020 10; 39(40):6286-6299. PMID: 32843721.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    12. Nishio M, To Y, Maehama T, Aono Y, Otani J, Hikasa H, Kitagawa A, Mimori K, Sasaki T, Nishina H, Toyokuni S, Lydon JP, Nakao K, Wah Mak T, Kiyono T, Katabuchi H, Tashiro H, Suzuki A. Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice. Cancer Sci. 2020 Oct; 111(10):3576-3587. PMID: 32716083.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    13. DeMayo FJ, Lydon JP. 90 YEARS OF PROGESTERONE: New insights into progesterone receptor signaling in the endometrium required for embryo implantation. J Mol Endocrinol. 2020 07; 65(1):T1-T14. PMID: 31809260.
      Citations: 4     Fields:    
    14. Goolam M, Xypolita ME, Costello I, Lydon JP, DeMayo FJ, Bikoff EK, Robertson EJ, Mould AW. The transcriptional repressor Blimp1/PRDM1 regulates the maternal decidual response in mice. Nat Commun. 2020 06 03; 11(1):2782. PMID: 32493987.
      Citations: 1     Fields:    Translation:AnimalsCells
    15. Oestreich AK, Chadchan SB, Medvedeva A, Lydon JP, Jungheim ES, Moley KH, Kommagani R. The autophagy protein, FIP200 (RB1CC1) mediates progesterone responses governing uterine receptivity and decidualization†. Biol Reprod. 2020 04 15; 102(4):843-851. PMID: 31901086.
      Citations: 3     Fields:    
    16. Park CJ, Lin PC, Zhou S, Barakat R, Bashir ST, Choi JM, Cacioppo JA, Oakley OR, Duffy DM, Lydon JP, Ko CJ. Progesterone Receptor Serves the Ovary as a Trigger of Ovulation and a Terminator of Inflammation. Cell Rep. 2020 04 14; 31(2):107496. PMID: 32294429.
      Citations: 3     Fields:    Translation:AnimalsCells
    17. Szekely E, Neumann A, Sallis H, Jolicoeur-Martineau A, Verhulst FC, Meaney MJ, Pearson RM, Levitan RD, Kennedy JL, Lydon JE, Steiner M, Greenwood CMT, Tiemeier H, Evans J, Wazana A. Maternal Prenatal Mood, Pregnancy-Specific Worries, and Early Child Psychopathology: Findings From the DREAM BIG Consortium. J Am Acad Child Adolesc Psychiatry. 2021 01; 60(1):186-197. PMID: 32278003.
      Citations: 2     Fields:    Translation:Humans
    18. Herrera GGB, Lierz SL, Harris EA, Donoghue LJ, Hewitt SC, Rodriguez KF, Jefferson WN, Lydon JP, DeMayo FJ, Williams CJ, Korach KS, Winuthayanon W. Oviductal Retention of Embryos in Female Mice Lacking Estrogen Receptor a in the Isthmus and the Uterus. Endocrinology. 2020 02 01; 161(2). PMID: 31883000.
      Citations: 1     Fields:    Translation:Animals
    19. Toufaily C, Schang G, Zhou X, Wartenberg P, Boehm U, Lydon JP, Roelfsema F, Bernard DJ. Impaired LH surge amplitude in gonadotrope-specific progesterone receptor knockout mice. J Endocrinol. 2020 01; 244(1):111-122. PMID: 31585440.
      Citations: 3     Fields:    Translation:AnimalsCells
    20. Oestreich AK, Chadchan SB, Popli P, Medvedeva A, Rowen MN, Stephens CS, Xu R, Lydon JP, Demayo FJ, Jungheim ES, Moley KH, Kommagani R. The Autophagy Gene Atg16L1 is Necessary for Endometrial Decidualization. Endocrinology. 2020 Jan 01; 161(1). PMID: 31875883.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    21. Nanjappa MK, Mesa AM, Medrano TI, Jefferson WN, DeMayo FJ, Williams CJ, Lydon JP, Levin ER, Cooke PS. The histone methyltransferase EZH2 is required for normal uterine development and function in mice†. Biol Reprod. 2019 08 01; 101(2):306-317. PMID: 31201420.
      Citations: 7     Fields:    Translation:AnimalsCells
    22. Hai L, Szwarc MM, Lonard DM, Rajapakshe K, Perera D, Coarfa C, Ittmann M, Fernandez-Valdivia R, Lydon JP. Short-term RANKL exposure initiates a neoplastic transcriptional program in the basal epithelium of the murine salivary gland. Cytokine. 2019 11; 123:154745. PMID: 31226438.
      Citations:    Fields:    Translation:AnimalsCells
    23. de Oliveira V, Schaefer J, Calder M, Lydon JP, DeMayo FJ, Bhattacharya M, Radovick S, Babwah AV. Uterine Gaq/11 signaling, in a progesterone-dependent manner, critically regulates the acquisition of uterine receptivity in the female mouse. FASEB J. 2019 08; 33(8):9374-9387. PMID: 31091422.
      Citations: 4     Fields:    Translation:AnimalsCells
    24. Hewitt SC, Lierz SL, Garcia M, Hamilton KJ, Gruzdev A, Grimm SA, Lydon JP, Demayo FJ, Korach KS. A distal super enhancer mediates estrogen-dependent mouse uterine-specific gene transcription of Igf1 (insulin-like growth factor 1). J Biol Chem. 2019 06 21; 294(25):9746-9759. PMID: 31073032.
      Citations: 6     Fields:    Translation:AnimalsCells
    25. Fang X, Ni N, Lydon JP, Ivanov I, Bayless KJ, Rijnkels M, Li Q. Enhancer of Zeste 2 Polycomb Repressive Complex 2 Subunit Is Required for Uterine Epithelial Integrity. Am J Pathol. 2019 06; 189(6):1212-1225. PMID: 30954472.
      Citations: 5     Fields:    Translation:Animals
    26. Thiele K, Hierweger AM, Riquelme JIA, Solano ME, Lydon JP, Arck PC. Impaired Progesterone-Responsiveness of CD11c+ Dendritic Cells Affects the Generation of CD4+ Regulatory T Cells and Is Associated With Intrauterine Growth Restriction in Mice. Front Endocrinol (Lausanne). 2019; 10:96. PMID: 30858825.
      Citations: 4     
    27. Szwarc MM, Hai L, Gibbons WE, Mo Q, Lanz RB, DeMayo FJ, Lydon JP. Early growth response 1 transcriptionally primes the human endometrial stromal cell for decidualization. J Steroid Biochem Mol Biol. 2019 05; 189:283-290. PMID: 30711473.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    28. Hierweger AM, Engler JB, Friese MA, Reichardt HM, Lydon J, DeMayo F, Mittrücker HW, Arck PC. Progesterone modulates the T-cell response via glucocorticoid receptor-dependent pathways. Am J Reprod Immunol. 2019 02; 81(2):e13084. PMID: 30604567.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    29. Hai L, Szwarc MM, Lanza DG, Heaney JD, Lydon JP. Using CRISPR/Cas9 engineering to generate a mouse with a conditional knockout allele for the promyelocytic leukemia zinc finger transcription factor. Genesis. 2019 03; 57(3):e23281. PMID: 30628160.
      Citations: 1     Fields:    Translation:Animals
    30. Ni N, Gao Y, Fang X, Melgar M, Vincent DF, Lydon JP, Bartholin L, Li Q. Glandular defects in the mouse uterus with sustained activation of TGF-beta signaling is associated with altered differentiation of endometrial stromal cells and formation of stromal compartment. PLoS One. 2018; 13(12):e0209417. PMID: 30550590.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    31. Vasquez YM, Wang X, Wetendorf M, Franco HL, Mo Q, Wang T, Lanz RB, Young SL, Lessey BA, Spencer TE, Lydon JP, DeMayo FJ. FOXO1 regulates uterine epithelial integrity and progesterone receptor expression critical for embryo implantation. PLoS Genet. 2018 11; 14(11):e1007787. PMID: 30452456.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    32. Wang X, Li X, Wang T, Wu SP, Jeong JW, Kim TH, Young SL, Lessey BA, Lanz RB, Lydon JP, DeMayo FJ. SOX17 regulates uterine epithelial-stromal cross-talk acting via a distal enhancer upstream of Ihh. Nat Commun. 2018 10 24; 9(1):4421. PMID: 30356064.
      Citations: 17     Fields:    Translation:AnimalsCells
    33. Hewitt SC, Li R, Adams N, Winuthayanon W, Hamilton KJ, Donoghue LJ, Lierz SL, Garcia M, Lydon JP, DeMayo FJ, Adelman K, Korach KS. Negative elongation factor is essential for endometrial function. FASEB J. 2019 02; 33(2):3010-3023. PMID: 30332301.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    34. Szwarc MM, Hai L, Gibbons WE, White LD, Mo Q, Kommagani R, Lanz RB, DeMayo FJ, O'Malley BW, Lydon JP. Retinoid signaling controlled by SRC-2 in decidualization revealed by transcriptomics Reproduction. 2018 10 16; 156(5):387-395. PMID: 30325183.
      Citations: 6     Fields:    Translation:HumansCells
    35. Szwarc MM, Kommagani R, Putluri V, Dubrulle J, Stossi F, Mancini MA, Coarfa C, Lanz RB, Putluri N, DeMayo FJ, Lydon JP, O'Malley BW. Steroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway through RPIA in Human Endometrial Cancer Cells. Sci Rep. 2018 09 03; 8(1):13134. PMID: 30177747.
      Citations: 1     Fields:    Translation:HumansCells
    36. Hai L, Szwarc MM, Wetendorf M, Wu SP, Peavey MC, Grimm SL, Edwards DP, DeMayo FJ, Lydon JP. A mouse model engineered to conditionally express the progesterone receptor-B isoform. Genesis. 2018 08; 56(8):e23223. PMID: 30004627.
      Citations: 1     Fields:    Translation:AnimalsCells
    37. Hai L, Szwarc MM, He B, Lonard DM, Kommagani R, DeMayo FJ, Lydon JP. Uterine function in the mouse requires speckle-type poz protein. Biol Reprod. 2018 06 01; 98(6):856-869. PMID: 29546395.
      Citations: 4     Fields:    Translation:Animals
    38. Szwarc MM, Hai L, Gibbons WE, Peavey MC, White LD, Mo Q, Lonard DM, Kommagani R, Lanz RB, DeMayo FJ, Lydon JP. Human endometrial stromal cell decidualization requires transcriptional reprogramming by PLZF. Biol Reprod. 2018 01 01; 98(1):15-27. PMID: 29186366.
      Citations: 6     Fields:    Translation:HumansCells
    39. Peavey MC, Reynolds CL, Szwarc MM, Gibbons WE, Valdes CT, DeMayo FJ, Lydon JP. A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse. J Vis Exp. 2017 10 24; (128). PMID: 29155779.
      Citations: 1     Fields:    Translation:Animals
    40. Camden AJ, Szwarc MM, Chadchan SB, DeMayo FJ, O'Malley BW, Lydon JP, Kommagani R. Growth regulation by estrogen in breast cancer 1 (GREB1) is a novel progesterone-responsive gene required for human endometrial stromal decidualization. Mol Hum Reprod. 2017 09 01; 23(9):646-653. PMID: 28911214.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    41. Gao Y, Lin P, Lydon JP, Li Q. Conditional abrogation of transforming growth factor-ß receptor 1 in PTEN-inactivated endometrium promotes endometrial cancer progression in mice. J Pathol. 2017 09; 243(1):89-99. PMID: 28657664.
      Citations: 9     Fields:    Translation:AnimalsCells
    42. Cui T, He B, Kong S, Zhou C, Zhang H, Ni Z, Bao H, Qiu J, Xin Q, Reinberg D, Lydon JP, Lu J, Wang H. PR-Set7 deficiency limits uterine epithelial population growth hampering postnatal gland formation in mice. Cell Death Differ. 2017 12; 24(12):2013-2021. PMID: 28731465.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    43. El Zowalaty AE, Li R, Zheng Y, Lydon JP, DeMayo FJ, Ye X. Deletion of RhoA in Progesterone Receptor-Expressing Cells Leads to Luteal Insufficiency and Infertility in Female Mice. Endocrinology. 2017 07 01; 158(7):2168-2178. PMID: 28498971.
      Citations: 7     Fields:    Translation:AnimalsCells
    44. Ran H, Kong S, Zhang S, Cheng J, Zhou C, He B, Xin Q, Lydon JP, DeMayo FJ, Feng GS, Xia G, Lu Z, Wang C, Wang H. Nuclear Shp2 directs normal embryo implantation via facilitating the ERa tyrosine phosphorylation by the Src kinase. Proc Natl Acad Sci U S A. 2017 05 02; 114(18):4816-4821. PMID: 28424251.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    45. Mapes J, Li Q, Kannan A, Anandan L, Laws M, Lydon JP, Bagchi IC, Bagchi MK. CUZD1 is a critical mediator of the JAK/STAT5 signaling pathway that controls mammary gland development during pregnancy. PLoS Genet. 2017 Mar; 13(3):e1006654. PMID: 28278176.
      Citations: 8     Fields:    Translation:AnimalsCells
    46. Szwarc MM, Kommagani R, Peavey MC, Hai L, Lonard DM, Lydon JP. A bioluminescence reporter mouse that monitors expression of constitutively active ß-catenin. PLoS One. 2017; 12(3):e0173014. PMID: 28253313.
      Citations: 2     Fields:    Translation:AnimalsCells
    47. Clark NC, Pru CA, Yee SP, Lydon JP, Peluso JJ, Pru JK. Conditional Ablation of Progesterone Receptor Membrane Component 2 Causes Female Premature Reproductive Senescence. Endocrinology. 2017 03 01; 158(3):640-651. PMID: 28005395.
      Citations: 13     Fields:    Translation:Animals
    48. Wetendorf M, Wu SP, Wang X, Creighton CJ, Wang T, Lanz RB, Blok L, Tsai SY, Tsai MJ, Lydon JP, DeMayo FJ. Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment. Biol Reprod. 2017 02 01; 96(2):313-326. PMID: 28203817.
      Citations: 19     Fields:    Translation:AnimalsCells
    49. Gargiulo L, May M, Rivero EM, Copsel S, Lamb C, Lydon J, Davio C, Lanari C, Lüthy IA, Bruzzone A. A Novel Effect of ß-Adrenergic Receptor on Mammary Branching Morphogenesis and its Possible Implications in Breast Cancer. J Mammary Gland Biol Neoplasia. 2017 03; 22(1):43-57. PMID: 28074314.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    50. Peavey MC, Reynolds CL, Szwarc MM, Gibbons WE, Valdes CT, DeMayo FJ, Lydon JP. Three-Dimensional High-Frequency Ultrasonography for Early Detection and Characterization of Embryo Implantation Site Development in the Mouse. PLoS One. 2017; 12(1):e0169312. PMID: 28046063.
      Citations: 3     Fields:    Translation:Animals
    51. Rubel CA, Wu SP, Lin L, Wang T, Lanz RB, Li X, Kommagani R, Franco HL, Camper SA, Tong Q, Jeong JW, Lydon JP, DeMayo FJ. A Gata2-Dependent Transcription Network Regulates Uterine Progesterone Responsiveness and Endometrial Function. Cell Rep. 2016 10 25; 17(5):1414-1425. PMID: 27783953.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    52. Xiao L, Feng Q, Zhang Z, Wang F, Lydon JP, Ittmann MM, Xin L, Mitsiades N, He B. The essential role of GATA transcription factors in adult murine prostate. Oncotarget. 2016 Jul 26; 7(30):47891-47903. PMID: 27374105.
      Citations: 5     Fields:    Translation:HumansAnimals
    53. Gal A, Lin PC, Cacioppo JA, Hannon PR, Mahoney MM, Wolfe A, Fernandez-Valdivia R, Lydon JP, Elias CF, Ko C. Loss of Fertility in the Absence of Progesterone Receptor Expression in Kisspeptin Neurons of Female Mice. PLoS One. 2016; 11(7):e0159534. PMID: 27441639.
      Citations: 10     Fields:    Translation:AnimalsCells
    54. McCallum ML, Pru CA, Niikura Y, Yee SP, Lydon JP, Peluso JJ, Pru JK. Conditional Ablation of Progesterone Receptor Membrane Component 1 Results in Subfertility in the Female and Development of Endometrial Cysts. Endocrinology. 2016 09; 157(9):3309-19. PMID: 27309940.
      Citations: 16     Fields:    Translation:Animals
    55. Xiao L, Lanz RB, Frolov A, Castro PD, Zhang Z, Dong B, Xue W, Jung SY, Lydon JP, Edwards DP, Mancini MA, Feng Q, Ittmann MM, He B. The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer Biomarker. Prostate. 2016 10; 76(14):1271-84. PMID: 27272765.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    56. Mehta FF, Son J, Hewitt SC, Jang E, Lydon JP, Korach KS, Chung SH. Distinct functions and regulation of epithelial progesterone receptor in the mouse cervix, vagina, and uterus. Oncotarget. 2016 Apr 05; 7(14):17455-67. PMID: 27007157.
      Citations: 9     Fields:    Translation:Animals
    57. Kommagani R, Szwarc MM, Vasquez YM, Peavey MC, Mazur EC, Gibbons WE, Lanz RB, DeMayo FJ, Lydon JP. The Promyelocytic Leukemia Zinc Finger Transcription Factor Is Critical for Human Endometrial Stromal Cell Decidualization. PLoS Genet. 2016 Apr; 12(4):e1005937. PMID: 27035670.
      Citations: 18     Fields:    Translation:HumansCells
    58. Vasquez YM, Wu SP, Anderson ML, Hawkins SM, Creighton CJ, Ray M, Tsai SY, Tsai MJ, Lydon JP, DeMayo FJ. Endometrial Expression of Steroidogenic Factor 1 Promotes Cystic Glandular Morphogenesis. Mol Endocrinol. 2016 May; 30(5):518-32. PMID: 27018534.
      Citations: 7     Fields:    Translation:AnimalsCells
    59. Shen J, Yao L, Lin YG, DeMayo FJ, Lydon JP, Dubeau L, Lee AS. Glucose-regulated protein 94 deficiency induces squamous cell metaplasia and suppresses PTEN-null driven endometrial epithelial tumor development. Oncotarget. 2016 Mar 22; 7(12):14885-97. PMID: 26910913.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    60. Stelzer IA, Mori M, DeMayo F, Lydon J, Arck PC, Solano ME. Differential mouse-strain specific expression of Junctional Adhesion Molecule (JAM)-B in placental structures. Cell Adh Migr. 2016 03 03; 10(1-2):2-17. PMID: 26914234.
      Citations: 1     Fields:    Translation:HumansAnimals
    61. Kim YS, Kim HR, Kim H, Yang SC, Park M, Yoon JA, Lim HJ, Hong SH, DeMayo FJ, Lydon JP, Choi Y, Lee DR, Song H. Deficiency in DGCR8-dependent canonical microRNAs causes infertility due to multiple abnormalities during uterine development in mice. Sci Rep. 2016 Feb 02; 6:20242. PMID: 26833131.
      Citations: 8     Fields:    Translation:AnimalsCells
    62. Monsivais D, Clementi C, Peng J, Titus MM, Barrish JP, Creighton CJ, Lydon JP, DeMayo FJ, Matzuk MM. Uterine ALK3 is essential during the window of implantation. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):E387-95. PMID: 26721398.
      Citations: 16     Fields:    Translation:AnimalsCells
    63. Whirledge SD, Oakley RH, Myers PH, Lydon JP, DeMayo F, Cidlowski JA. Uterine glucocorticoid receptors are critical for fertility in mice through control of embryo implantation and decidualization. Proc Natl Acad Sci U S A. 2015 Dec 08; 112(49):15166-71. PMID: 26598666.
      Citations: 18     Fields:    Translation:Animals
    64. Szwarc MM, Kommagani R, Jeong JW, Wu SP, Tsai SY, Tsai MJ, O'Malley BW, DeMayo FJ, Lydon JP. Correction: Perturbing the Cellular Levels of Steroid Receptor Coactivator-2 Impairs Murine Endometrial Function. PLoS One. 2015; 10(11):e0143652. PMID: 26580555.
      Citations:    Fields:    
    65. Han SJ, Jung SY, Wu SP, Hawkins SM, Park MJ, Kyo S, Qin J, Lydon JP, Tsai SY, Tsai MJ, DeMayo FJ, O'Malley BW. Estrogen Receptor ß Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis. Cell. 2015 Nov 05; 163(4):960-74. PMID: 26544941.
      Citations: 76     Fields:    Translation:HumansAnimals
    66. Convissar SM, Bennett J, Baumgarten SC, Lydon JP, DeMayo FJ, Stocco C. GATA4 and GATA6 Knockdown During Luteinization Inhibits Progesterone Production and Gonadotropin Responsiveness in the Corpus Luteum of Female Mice. Biol Reprod. 2015 Dec; 93(6):133. PMID: 26510866.
      Citations: 6     Fields:    Translation:AnimalsCells
    67. Bhowmik SK, Putluri V, Kommagani R, Konde SA, Lydon JP, Sreekumar A, Putluri N. Application of (13) C isotope labeling using liquid chromatography mass spectrometry (LC-MS) to determining phosphate-containing metabolic incorporation. J Mass Spectrom. 2015 Oct; 50(10):1180. PMID: 26456788.
      Citations:    Fields:    
    68. Kommagani R, Szwarc MM, Kovanci E, Gibbons WE, Putluri N, Maity S, Creighton CJ, Sreekumar A, DeMayo FJ, Lydon JP, O'Malley BW. Correction: Acceleration of the Glycolytic Flux by Steroid Receptor Coactivator-2 Is Essential for Endometrial Decidualization. PLoS Genet. 2015 Sep; 11(9):e1005515. PMID: 26418340.
      Citations: 1     Fields:    
    69. Kim TH, Yoo JY, Wang Z, Lydon JP, Khatri S, Hawkins SM, Leach RE, Fazleabas AT, Young SL, Lessey BA, Ku BJ, Jeong JW. ARID1A Is Essential for Endometrial Function during Early Pregnancy. PLoS Genet. 2015 Sep; 11(9):e1005537. PMID: 26378916.
      Citations: 26     Fields:    Translation:HumansAnimals
    70. Szwarc MM, Lydon JP, O'Malley BW. Reprint of "Steroid receptor coactivators as therapeutic targets in the female reproductive system". J Steroid Biochem Mol Biol. 2015 Sep; 153:144-50. PMID: 26291832.
      Citations:    Fields:    
    71. Szwarc MM, Lydon JP, O'Malley BW. Steroid receptor coactivators as therapeutic targets in the female reproductive system. J Steroid Biochem Mol Biol. 2015 Nov; 154:32-8. PMID: 26151740.
      Citations: 3     Fields:    Translation:HumansAnimals
    72. Szwarc MM, Kommagani R, Jacob AP, Dougall WC, Ittmann MM, Lydon JP. Aberrant Activation of the RANK Signaling Receptor Induces Murine Salivary Gland Tumors. PLoS One. 2015; 10(6):e0128467. PMID: 26061636.
      Citations: 3     Fields:    Translation:AnimalsCells
    73. Nanjappa MK, Medrano TI, Lydon JP, Bigsby RM, Cooke PS. Maximal Dexamethasone Inhibition of Luminal Epithelial Proliferation Involves Progesterone Receptor (PR)- and Non-PR-Mediated Mechanisms in Neonatal Mouse Uterus. Biol Reprod. 2015 May; 92(5):122. PMID: 25882702.
      Citations: 3     Fields:    Translation:AnimalsCells
    74. Solano ME, Kowal MK, O'Rourke GE, Horst AK, Modest K, Plösch T, Barikbin R, Remus CC, Berger RG, Jago C, Ho H, Sass G, Parker VJ, Lydon JP, DeMayo FJ, Hecher K, Karimi K, Arck PC. Progesterone and HMOX-1 promote fetal growth by CD8+ T cell modulation. J Clin Invest. 2015 Apr; 125(4):1726-38. PMID: 25774501.
      Citations: 17     Fields:    Translation:AnimalsCellsPHPublic Health
    75. Shiah YJ, Tharmapalan P, Casey AE, Joshi PA, McKee TD, Jackson HW, Beristain AG, Chan-Seng-Yue MA, Bader GD, Lydon JP, Waterhouse PD, Boutros PC, Khokha R. A Progesterone-CXCR4 Axis Controls Mammary Progenitor Cell Fate in the Adult Gland. Stem Cell Reports. 2015 Mar 10; 4(3):313-322. PMID: 28447939.
      Citations: 14     Fields:    
    76. Bangari DS, Ashe KM, Desnick RJ, Maloney C, Lydon J, Piepenhagen P, Budman E, Leonard JP, Cheng SH, Marshall J, Thurberg BL. a-Galactosidase A knockout mice: progressive organ pathology resembles the type 2 later-onset phenotype of Fabry disease. Am J Pathol. 2015 Mar; 185(3):651-65. PMID: 25553976.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    77. Gao Y, Duran S, Lydon JP, DeMayo FJ, Burghardt RC, Bayless KJ, Bartholin L, Li Q. Constitutive activation of transforming growth factor Beta receptor 1 in the mouse uterus impairs uterine morphology and function. Biol Reprod. 2015 Feb; 92(2):34. PMID: 25505200.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    78. Grimm SL, Ward RD, Obr AE, Franco HL, Fernandez-Valdivia R, Kim JS, Roberts JM, Jeong JW, DeMayo FJ, Lydon JP, Edwards DP, Weigel NL. A role for site-specific phosphorylation of mouse progesterone receptor at serine 191 in vivo. Mol Endocrinol. 2014 Dec; 28(12):2025-37. PMID: 25333515.
      Citations: 1     Fields:    Translation:AnimalsCells
    79. Akgul Y, Word RA, Ensign LM, Yamaguchi Y, Lydon J, Hanes J, Mahendroo M. Hyaluronan in cervical epithelia protects against infection-mediated preterm birth. J Clin Invest. 2014 Dec; 124(12):5481-9. PMID: 25384213.
      Citations: 26     Fields:    Translation:Animals
    80. Kim TH, Yoo JY, Kim HI, Gilbert J, Ku BJ, Li J, Mills GB, Broaddus RR, Lydon JP, Lim JM, Yoon HG, Jeong JW. Mig-6 suppresses endometrial cancer associated with Pten deficiency and ERK activation. Cancer Res. 2014 Dec 15; 74(24):7371-82. PMID: 25377472.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    81. Szwarc MM, Kommagani R, Lessey BA, Lydon JP. The p160/steroid receptor coactivator family: potent arbiters of uterine physiology and dysfunction. Biol Reprod. 2014 Nov; 91(5):122. PMID: 25297546.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    82. Zhang S, Kong S, Wang B, Cheng X, Chen Y, Wu W, Wang Q, Shi J, Zhang Y, Wang S, Lu J, Lydon JP, DeMayo F, Pear WS, Han H, Lin H, Li L, Wang H, Wang YL, Li B, Chen Q, Duan E, Wang H. Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms. Cell Res. 2014 Aug; 24(8):925-42. PMID: 24971735.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    83. Large MJ, Wetendorf M, Lanz RB, Hartig SM, Creighton CJ, Mancini MA, Kovanci E, Lee KF, Threadgill DW, Lydon JP, Jeong JW, DeMayo FJ. The epidermal growth factor receptor critically regulates endometrial function during early pregnancy. PLoS Genet. 2014 Jun; 10(6):e1004451. PMID: 24945252.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    84. Szwarc MM, Kommagani R, Jeong JW, Wu SP, Tsai SY, Tsai MJ, O'Malley BW, DeMayo FJ, Lydon JP. Perturbing the cellular levels of steroid receptor coactivator-2 impairs murine endometrial function. PLoS One. 2014; 9(6):e98664. PMID: 24905738.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    85. Putluri N, Maity S, Kommagani R, Kommangani R, Creighton CJ, Putluri V, Chen F, Nanda S, Bhowmik SK, Terunuma A, Dorsey T, Nardone A, Fu X, Shaw C, Sarkar TR, Schiff R, Lydon JP, O'Malley BW, Ambs S, Das GM, Michailidis G, Sreekumar A. Pathway-centric integrative analysis identifies RRM2 as a prognostic marker in breast cancer associated with poor survival and tamoxifen resistance. Neoplasia. 2014 May; 16(5):390-402. PMID: 25016594.
      Citations: 27     Fields:    Translation:HumansCells
    86. Kommagani R, Szwarc MM, Kovanci E, Creighton CJ, O'Malley BW, Demayo FJ, Lydon JP. A murine uterine transcriptome, responsive to steroid receptor coactivator-2, reveals transcription factor 23 as essential for decidualization of human endometrial stromal cells. Biol Reprod. 2014 Apr; 90(4):75. PMID: 24571987.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    87. van der Horst PH, van der Zee M, Heijmans-Antonissen C, Jia Y, DeMayo FJ, Lydon JP, van Deurzen CH, Ewing PC, Burger CW, Blok LJ. A mouse model for endometrioid ovarian cancer arising from the distal oviduct. Int J Cancer. 2014 Sep 01; 135(5):1028-37. PMID: 24474556.
      Citations: 11     Fields:    Translation:AnimalsCells
    88. Kim TH, Yu Y, Luo L, Lydon JP, Jeong JW, Kim JJ. Activated AKT pathway promotes establishment of endometriosis. Endocrinology. 2014 May; 155(5):1921-30. PMID: 24605828.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    89. Filant J, DeMayo FJ, Pru JK, Lydon JP, Spencer TE. Fibroblast growth factor receptor two (FGFR2) regulates uterine epithelial integrity and fertility in mice. Biol Reprod. 2014 Jan; 90(1):7. PMID: 24227756.
      Citations: 11     Fields:    Translation:AnimalsCells
    90. Bhowmik SK, Putluri V, Kommagani R, Konde SA, Lydon JP, Sreekumar A, Putluri N. Application of 13C isotope labeling using liquid chromatography mass spectrometry (LC-MS) to determining phosphate-containing metabolic incorporation. J Mass Spectrom. 2013 Dec; 48(12):1270-5. PMID: 24338880.
      Citations:    Fields:    Translation:HumansCells
    91. Clementi C, Tripurani SK, Large MJ, Edson MA, Creighton CJ, Hawkins SM, Kovanci E, Kaartinen V, Lydon JP, Pangas SA, DeMayo FJ, Matzuk MM. Activin-like kinase 2 functions in peri-implantation uterine signaling in mice and humans. PLoS Genet. 2013 Nov; 9(11):e1003863. PMID: 24244176.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    92. Bruno RD, Boulanger CA, Rosenfield SM, Anderson LH, Lydon JP, Smith GH. Paracrine-rescued lobulogenesis in chimeric outgrowths comprising progesterone-receptor-null mammary epithelium and redirected wild-type testicular cells. J Cell Sci. 2014 Jan 01; 127(Pt 1):27-32. PMID: 24190884.
      Citations: 7     Fields:    Translation:AnimalsCells
    93. Kommagani R, Szwarc MM, Kovanci E, Gibbons WE, Putluri N, Maity S, Creighton CJ, Sreekumar A, DeMayo FJ, Lydon JP, O'Malley BW. Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. PLoS Genet. 2013 Oct; 9(10):e1003900. PMID: 24204309.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    94. Oh SJ, Shin JH, Kim TH, Lee HS, Yoo JY, Ahn JY, Broaddus RR, Taketo MM, Lydon JP, Leach RE, Lessey BA, Fazleabas AT, Lim JM, Jeong JW. ß-Catenin activation contributes to the pathogenesis of adenomyosis through epithelial-mesenchymal transition. J Pathol. 2013 Oct; 231(2):210-22. PMID: 23784889.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    95. Filant J, Lydon JP, Spencer TE. Integrated chromatin immunoprecipitation sequencing and microarray analysis identifies FOXA2 target genes in the glands of the mouse uterus. FASEB J. 2014 Jan; 28(1):230-43. PMID: 24025729.
      Citations: 21     Fields:    Translation:Animals
    96. Obr AE, Grimm SL, Bishop KA, Pike JW, Lydon JP, Edwards DP. Progesterone receptor and Stat5 signaling cross talk through RANKL in mammary epithelial cells. Mol Endocrinol. 2013 Nov; 27(11):1808-24. PMID: 24014651.
      Citations: 24     Fields:    Translation:AnimalsCells
    97. Yoo YA, Son J, Mehta FF, DeMayo FJ, Lydon JP, Chung SH. Progesterone signaling inhibits cervical carcinogenesis in mice. Am J Pathol. 2013 Nov; 183(5):1679-1687. PMID: 24012679.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    98. Kim M, Park HJ, Seol JW, Jang JY, Cho YS, Kim KR, Choi Y, Lydon JP, Demayo FJ, Shibuya M, Ferrara N, Sung HK, Nagy A, Alitalo K, Koh GY. VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy. EMBO Mol Med. 2013 Sep; 5(9):1415-30. PMID: 23853117.
      Citations: 47     Fields:    Translation:Animals
    99. Lindberg ME, Stodden GR, King ML, MacLean JA, Mann JL, DeMayo FJ, Lydon JP, Hayashi K. Loss of CDH1 and Pten accelerates cellular invasiveness and angiogenesis in the mouse uterus. Biol Reprod. 2013 Jul; 89(1):8. PMID: 23740945.
      Citations: 7     Fields:    Translation:AnimalsCells
    100. Prizant H, Sen A, Light A, Cho SN, DeMayo FJ, Lydon JP, Hammes SR. Uterine-specific loss of Tsc2 leads to myometrial tumors in both the uterus and lungs. Mol Endocrinol. 2013 Sep; 27(9):1403-14. PMID: 23820898.
      Citations: 20     Fields:    Translation:Animals
    101. Zhang C, Large MJ, Duggavathi R, DeMayo FJ, Lydon JP, Schoonjans K, Kovanci E, Murphy BD. Liver receptor homolog-1 is essential for pregnancy. Nat Med. 2013 Aug; 19(8):1061-6. PMID: 23817023.
      Citations: 25     Fields:    Translation:HumansAnimals
    102. Kim TH, Lee DK, Cho SN, Orvis GD, Behringer RR, Lydon JP, Ku BJ, McCampbell AS, Broaddus RR, Jeong JW. Critical tumor suppressor function mediated by epithelial Mig-6 in endometrial cancer. Cancer Res. 2013 Aug 15; 73(16):5090-9. PMID: 23811943.
      Citations: 13     Fields:    Translation:AnimalsCells
    103. Nagashima T, Li Q, Clementi C, Lydon JP, DeMayo FJ, Matzuk MM. BMPR2 is required for postimplantation uterine function and pregnancy maintenance. J Clin Invest. 2013 Jun; 123(6):2539-50. PMID: 23676498.
      Citations: 45     Fields:    Translation:AnimalsCells
    104. Lee JH, Kim TH, Oh SJ, Yoo JY, Akira S, Ku BJ, Lydon JP, Jeong JW. Signal transducer and activator of transcription-3 (Stat3) plays a critical role in implantation via progesterone receptor in uterus. FASEB J. 2013 Jul; 27(7):2553-63. PMID: 23531596.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    105. van der Zee M, Jia Y, Wang Y, Heijmans-Antonissen C, Ewing PC, Franken P, DeMayo FJ, Lydon JP, Burger CW, Fodde R, Blok LJ. Alterations in Wnt-ß-catenin and Pten signalling play distinct roles in endometrial cancer initiation and progression. J Pathol. 2013 May; 230(1):48-58. PMID: 23288720.
      Citations: 17     Fields:    Translation:AnimalsCells
    106. Lee HJ, Gallego-Ortega D, Ledger A, Schramek D, Joshi P, Szwarc MM, Cho C, Lydon JP, Khokha R, Penninger JM, Ormandy CJ. Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells. Development. 2013 Apr; 140(7):1397-401. PMID: 23462470.
      Citations: 39     Fields:    Translation:AnimalsCells
    107. Lue Y, Wang C, Lydon JP, Leung A, Li J, Swerdloff RS. Functional role of progestin and the progesterone receptor in the suppression of spermatogenesis in rodents. Andrology. 2013 Mar; 1(2):308-17. PMID: 23408752.
      Citations: 6     Fields:    Translation:AnimalsCells
    108. Kawagoe J, Li Q, Mussi P, Liao L, Lydon JP, DeMayo FJ, Xu J. Nuclear receptor coactivator-6 attenuates uterine estrogen sensitivity to permit embryo implantation. Dev Cell. 2012 Oct 16; 23(4):858-65. PMID: 23079602.
      Citations: 17     Fields:    Translation:Animals
    109. Lee JH, Lydon JP, Kim CH. Progesterone suppresses the mTOR pathway and promotes generation of induced regulatory T cells with increased stability. Eur J Immunol. 2012 Oct; 42(10):2683-96. PMID: 22740122.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    110. Hawkins SM, Andreu-Vieyra CV, Kim TH, Jeong JW, Hodgson MC, Chen R, Creighton CJ, Lydon JP, Gunaratne PH, DeMayo FJ, Matzuk MM. Dysregulation of uterine signaling pathways in progesterone receptor-Cre knockout of dicer. Mol Endocrinol. 2012 Sep; 26(9):1552-66. PMID: 22798293.
      Citations: 14     Fields:    Translation:AnimalsCells
    111. Han SJ, Hawkins SM, Begum K, Jung SY, Kovanci E, Qin J, Lydon JP, DeMayo FJ, O'Malley BW. A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis. Nat Med. 2012 Jul; 18(7):1102-11. PMID: 22660634.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    112. Park CB, DeMayo FJ, Lydon JP, Dufort D. NODAL in the uterus is necessary for proper placental development and maintenance of pregnancy. Biol Reprod. 2012 Jun; 86(6):194. PMID: 22378764.
      Citations: 15     Fields:    Translation:Animals
    113. Rubel CA, Lanz RB, Kommagani R, Franco HL, Lydon JP, DeMayo FJ. Research resource: Genome-wide profiling of progesterone receptor binding in the mouse uterus. Mol Endocrinol. 2012 Aug; 26(8):1428-42. PMID: 22638070.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    114. Liu A, Margaill I, Zhang S, Labombarda F, Coqueran B, Delespierre B, Liere P, Marchand-Leroux C, O'Malley BW, Lydon JP, De Nicola AF, Sitruk-Ware R, Mattern C, Plotkine M, Schumacher M, Guennoun R. Progesterone receptors: a key for neuroprotection in experimental stroke. Endocrinology. 2012 Aug; 153(8):3747-57. PMID: 22635678.
      Citations: 36     Fields:    Translation:AnimalsCells
    115. Park S, Yoon S, Zhao Y, Park SE, Liao L, Xu J, Lydon JP, DeMayo FJ, O'Malley BW, Bagchi MK, Katzenellenbogen BS. Uterine development and fertility are dependent on gene dosage of the nuclear receptor coregulator REA. Endocrinology. 2012 Aug; 153(8):3982-94. PMID: 22585830.
      Citations: 11     Fields:    Translation:AnimalsCells
    116. Reardon SN, King ML, MacLean JA, Mann JL, DeMayo FJ, Lydon JP, Hayashi K. CDH1 is essential for endometrial differentiation, gland development, and adult function in the mouse uterus. Biol Reprod. 2012 May; 86(5):141, 1-10. PMID: 22378759.
      Citations: 35     Fields:    Translation:AnimalsCells
    117. Rubel CA, Franco HL, Jeong JW, Lydon JP, DeMayo FJ. GATA2 is expressed at critical times in the mouse uterus during pregnancy. Gene Expr Patterns. 2012 May-Jun; 12(5-6):196-203. PMID: 22476030.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    118. Franco HL, Rubel CA, Large MJ, Wetendorf M, Fernandez-Valdivia R, Jeong JW, Spencer TE, Behringer RR, Lydon JP, Demayo FJ. Epithelial progesterone receptor exhibits pleiotropic roles in uterine development and function. FASEB J. 2012 Mar; 26(3):1218-27. PMID: 22155565.
      Citations: 65     Fields:    Translation:AnimalsCells
    119. Daikoku T, Cha J, Sun X, Tranguch S, Xie H, Fujita T, Hirota Y, Lydon J, DeMayo F, Maxson R, Dey SK. Conditional deletion of Msx homeobox genes in the uterus inhibits blastocyst implantation by altering uterine receptivity. Dev Cell. 2011 Dec 13; 21(6):1014-25. PMID: 22100262.
      Citations: 76     Fields:    Translation:AnimalsCells
    120. Afshar Y, Jeong JW, Roqueiro D, DeMayo F, Lydon J, Radtke F, Radnor R, Miele L, Fazleabas A. Notch1 mediates uterine stromal differentiation and is critical for complete decidualization in the mouse. FASEB J. 2012 Jan; 26(1):282-94. PMID: 21990372.
      Citations: 33     Fields:    Translation:AnimalsCells
    121. Fernandez-Valdivia R, Lydon JP. From the ranks of mammary progesterone mediators, RANKL takes the spotlight. Mol Cell Endocrinol. 2012 Jun 24; 357(1-2):91-100. PMID: 21964466.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    122. Nagashima T, Kim J, Li Q, Lydon JP, DeMayo FJ, Lyons KM, Matzuk MM. Connective tissue growth factor is required for normal follicle development and ovulation. Mol Endocrinol. 2011 Oct; 25(10):1740-59. PMID: 21868453.
      Citations: 31     Fields:    Translation:AnimalsCells
    123. Park S, Zhao Y, Yoon S, Xu J, Liao L, Lydon J, DeMayo F, O'Malley BW, Katzenellenbogen BS. Repressor of estrogen receptor activity (REA) is essential for mammary gland morphogenesis and functional activities: studies in conditional knockout mice. Endocrinology. 2011 Nov; 152(11):4336-49. PMID: 21862609.
      Citations: 12     Fields:    Translation:AnimalsCells
    124. Wang Y, Jia Y, Franken P, Smits R, Ewing PC, Lydon JP, DeMayo FJ, Burger CW, Anton Grootegoed J, Fodde R, Blok LJ. Loss of APC function in mesenchymal cells surrounding the Müllerian duct leads to myometrial defects in adult mice. Mol Cell Endocrinol. 2011 Jul 20; 341(1-2):48-54. PMID: 21664244.
      Citations: 7     Fields:    Translation:AnimalsCells
    125. Dunlap KA, Filant J, Hayashi K, Rucker EB, Song G, Deng JM, Behringer RR, DeMayo FJ, Lydon J, Jeong JW, Spencer TE. Postnatal deletion of Wnt7a inhibits uterine gland morphogenesis and compromises adult fertility in mice. Biol Reprod. 2011 Aug; 85(2):386-96. PMID: 21508348.
      Citations: 51     Fields:    Translation:Animals
    126. Li Q, Kannan A, DeMayo FJ, Lydon JP, Cooke PS, Yamagishi H, Srivastava D, Bagchi MK, Bagchi IC. The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2. Science. 2011 Feb 18; 331(6019):912-6. PMID: 21330545.
      Citations: 135     Fields:    Translation:AnimalsCells
    127. He B, Kim TH, Kommagani R, Feng Q, Lanz RB, Jeong JW, DeMayo FJ, Katzenellenbogen BS, Lydon JP, O'Malley BW. Estrogen-regulated prohibitin is required for mouse uterine development and adult function. Endocrinology. 2011 Mar; 152(3):1047-56. PMID: 21209023.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    128. Franco HL, Dai D, Lee KY, Rubel CA, Roop D, Boerboom D, Jeong JW, Lydon JP, Bagchi IC, Bagchi MK, DeMayo FJ. WNT4 is a key regulator of normal postnatal uterine development and progesterone signaling during embryo implantation and decidualization in the mouse. FASEB J. 2011 Apr; 25(4):1176-87. PMID: 21163860.
      Citations: 116     Fields:    Translation:AnimalsCells
    129. Mukherjee A, Soyal SM, Li J, Ying Y, Szwarc MM, He B, Kommagani R, Hodgson MC, Hiremath M, Cowin P, Lydon JP. A mouse transgenic approach to induce ß-catenin signaling in a temporally controlled manner. Transgenic Res. 2011 Aug; 20(4):827-40. PMID: 21120693.
      Citations: 5     Fields:    Translation:AnimalsCells
    130. Lydon JP, O'Malley BW. Minireview: steroid receptor coactivator-3: a multifarious coregulator in mammary gland metastasis. Endocrinology. 2011 Jan; 152(1):19-25. PMID: 21047941.
      Citations: 23     Fields:    Translation:HumansCells
    131. Hayashi K, Yoshioka S, Reardon SN, Rucker EB, Spencer TE, DeMayo FJ, Lydon JP, MacLean JA. WNTs in the neonatal mouse uterus: potential regulation of endometrial gland development. Biol Reprod. 2011 Feb; 84(2):308-19. PMID: 20962251.
      Citations: 39     Fields:    Translation:Animals
    132. Mukherjee A, Soyal SM, Li J, Ying Y, He B, DeMayo FJ, Lydon JP. Targeting RANKL to a specific subset of murine mammary epithelial cells induces ordered branching morphogenesis and alveologenesis in the absence of progesterone receptor expression. FASEB J. 2010 Nov; 24(11):4408-19. PMID: 20605949.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    133. Lydon JP. Stem cells: Cues from steroid hormones. Nature. 2010 Jun 10; 465(7299):695-6. PMID: 20535190.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    134. Jeong JW, Kwak I, Lee KY, Kim TH, Large MJ, Stewart CL, Kaestner KH, Lydon JP, DeMayo FJ. Foxa2 is essential for mouse endometrial gland development and fertility. Biol Reprod. 2010 Sep; 83(3):396-403. PMID: 20484741.
      Citations: 80     Fields:    Translation:Animals
    135. Kim TH, Franco HL, Jung SY, Qin J, Broaddus RR, Lydon JP, Jeong JW. The synergistic effect of Mig-6 and Pten ablation on endometrial cancer development and progression. Oncogene. 2010 Jul 01; 29(26):3770-80. PMID: 20418913.
      Citations: 28     Fields:    Translation:AnimalsCells
    136. Lee DK, Kurihara I, Jeong JW, Lydon JP, DeMayo FJ, Tsai MJ, Tsai SY. Suppression of ERalpha activity by COUP-TFII is essential for successful implantation and decidualization. Mol Endocrinol. 2010 May; 24(5):930-40. PMID: 20219888.
      Citations: 33     Fields:    Translation:Animals
    137. Franco HL, Lee KY, Rubel CA, Creighton CJ, White LD, Broaddus RR, Lewis MT, Lydon JP, Jeong JW, DeMayo FJ. Constitutive activation of smoothened leads to female infertility and altered uterine differentiation in the mouse. Biol Reprod. 2010 May; 82(5):991-9. PMID: 20130264.
      Citations: 27     Fields:    Translation:AnimalsCells
    138. Fernandez-Valdivia R, Jeong J, Mukherjee A, Soyal SM, Li J, Ying Y, Demayo FJ, Lydon JP. A mouse model to dissect progesterone signaling in the female reproductive tract and mammary gland. Genesis. 2010 Feb; 48(2):106-13. PMID: 20029965.
      Citations: 29     Fields:    Translation:AnimalsCells
    139. Rubel CA, Jeong JW, Tsai SY, Lydon JP, Demayo FJ. Epithelial-stromal interaction and progesterone receptors in the mouse uterus. Semin Reprod Med. 2010 Jan; 28(1):27-35. PMID: 20104426.
      Citations: 27     Fields:    Translation:AnimalsCells
    140. Franco HL, Lee KY, Broaddus RR, White LD, Lanske B, Lydon JP, Jeong JW, DeMayo FJ. Ablation of Indian hedgehog in the murine uterus results in decreased cell cycle progression, aberrant epidermal growth factor signaling, and increased estrogen signaling. Biol Reprod. 2010 Apr; 82(4):783-90. PMID: 20056671.
      Citations: 29     Fields:    Translation:AnimalsCells
    141. Kim TH, Lee DK, Franco HL, Lydon JP, Jeong JW. ERBB receptor feedback inhibitor 1 regulation of estrogen receptor activity is critical for uterine implantation in mice. Biol Reprod. 2010 Apr; 82(4):706-13. PMID: 20018910.
      Citations: 17     Fields:    Translation:Animals
    142. Labombarda F, Meffre D, Delespierre B, Krivokapic-Blondiaux S, Chastre A, Thomas P, Pang Y, Lydon JP, Gonzalez SL, De Nicola AF, Schumacher M, Guennoun R. Membrane progesterone receptors localization in the mouse spinal cord. Neuroscience. 2010 Mar 10; 166(1):94-106. PMID: 20025939.
      Citations: 32     Fields:    Translation:AnimalsCells
    143. Kim TH, Wang J, Lee KY, Franco HL, Broaddus RR, Lydon JP, Jeong JW, Demayo FJ. The Synergistic Effect of Conditional Pten Loss and Oncogenic K-ras Mutation on Endometrial Cancer Development Occurs via Decreased Progesterone Receptor Action. J Oncol. 2010; 2010:139087. PMID: 19884980.
      Citations: 23     
    144. Fan HY, Liu Z, Paquet M, Wang J, Lydon JP, DeMayo FJ, Richards JS. Cell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cells. Cancer Res. 2009 Aug 15; 69(16):6463-72. PMID: 19679546.
      Citations: 47     Fields:    Translation:AnimalsCells
    145. Lydon JP, Edwards DP. Finally! A model for progesterone receptor action in normal human breast. Endocrinology. 2009 Jul; 150(7):2988-90. PMID: 19549883.
      Citations: 5     Fields:    Translation:HumansAnimals
    146. Jeong JW, Lee HS, Lee KY, White LD, Broaddus RR, Zhang YW, Vande Woude GF, Giudice LC, Young SL, Lessey BA, Tsai SY, Lydon JP, DeMayo FJ. Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease. Proc Natl Acad Sci U S A. 2009 May 26; 106(21):8677-82. PMID: 19439667.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    147. Simon L, Spiewak KA, Ekman GC, Kim J, Lydon JP, Bagchi MK, Bagchi IC, DeMayo FJ, Cooke PS. Stromal progesterone receptors mediate induction of Indian Hedgehog (IHH) in uterine epithelium and its downstream targets in uterine stroma. Endocrinology. 2009 Aug; 150(8):3871-6. PMID: 19372202.
      Citations: 31     Fields:    Translation:Animals
    148. Jodhka PK, Kaur P, Underwood W, Lydon JP, Singh M. The differences in neuroprotective efficacy of progesterone and medroxyprogesterone acetate correlate with their effects on brain-derived neurotrophic factor expression. Endocrinology. 2009 Jul; 150(7):3162-8. PMID: 19325006.
      Citations: 28     Fields:    Translation:AnimalsCells
    149. Fernandez-Valdivia R, Mukherjee A, Ying Y, Li J, Paquet M, DeMayo FJ, Lydon JP. The RANKL signaling axis is sufficient to elicit ductal side-branching and alveologenesis in the mammary gland of the virgin mouse. Dev Biol. 2009 Apr 01; 328(1):127-39. PMID: 19298785.
      Citations: 60     Fields:    Translation:AnimalsCells
    150. Jeong JW, Lee HS, Franco HL, Broaddus RR, Taketo MM, Tsai SY, Lydon JP, DeMayo FJ. beta-catenin mediates glandular formation and dysregulation of beta-catenin induces hyperplasia formation in the murine uterus. Oncogene. 2009 Jan 08; 28(1):31-40. PMID: 18806829.
      Citations: 86     Fields:    Translation:Animals
    151. Fernandez-Valdivia R, Mukherjee A, Creighton CJ, Buser AC, DeMayo FJ, Edwards DP, Lydon JP. Transcriptional response of the murine mammary gland to acute progesterone exposure. Endocrinology. 2008 Dec; 149(12):6236-50. PMID: 18687774.
      Citations: 37     Fields:    Translation:AnimalsCells
    152. Daikoku T, Hirota Y, Tranguch S, Joshi AR, DeMayo FJ, Lydon JP, Ellenson LH, Dey SK. Conditional loss of uterine Pten unfailingly and rapidly induces endometrial cancer in mice. Cancer Res. 2008 Jul 15; 68(14):5619-27. PMID: 18632614.
      Citations: 107     Fields:    Translation:AnimalsCells
    153. Laws MJ, Taylor RN, Sidell N, DeMayo FJ, Lydon JP, Gutstein DE, Bagchi MK, Bagchi IC. Gap junction communication between uterine stromal cells plays a critical role in pregnancy-associated neovascularization and embryo survival. Development. 2008 Aug; 135(15):2659-68. PMID: 18599509.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    154. Rickard DJ, Iwaniec UT, Evans G, Hefferan TE, Hunter JC, Waters KM, Lydon JP, O'Malley BW, Khosla S, Spelsberg TC, Turner RT. Bone growth and turnover in progesterone receptor knockout mice. Endocrinology. 2008 May; 149(5):2383-90. PMID: 18276762.
      Citations: 18     Fields:    Translation:AnimalsCells
    155. Franco HL, Jeong JW, Tsai SY, Lydon JP, DeMayo FJ. In vivo analysis of progesterone receptor action in the uterus during embryo implantation. Semin Cell Dev Biol. 2008 Apr; 19(2):178-86. PMID: 18280760.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    156. Kim J, Sato M, Li Q, Lydon JP, Demayo FJ, Bagchi IC, Bagchi MK. Peroxisome proliferator-activated receptor gamma is a target of progesterone regulation in the preovulatory follicles and controls ovulation in mice. Mol Cell Biol. 2008 Mar; 28(5):1770-82. PMID: 18172011.
      Citations: 43     Fields:    Translation:AnimalsCells
    157. Mukherjee A, Amato P, Allred DC, DeMayo FJ, Lydon JP. Steroid receptor coactivator 2 is required for female fertility and mammary morphogenesis: insights from the mouse, relevance to the human. Nucl Recept Signal. 2007 Nov 30; 5:e011. PMID: 18174919.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    158. Xie H, Wang H, Tranguch S, Iwamoto R, Mekada E, Demayo FJ, Lydon JP, Das SK, Dey SK. Maternal heparin-binding-EGF deficiency limits pregnancy success in mice. Proc Natl Acad Sci U S A. 2007 Nov 13; 104(46):18315-20. PMID: 17986609.
      Citations: 42     Fields:    Translation:Animals
    159. He B, Feng Q, Mukherjee A, Lonard DM, DeMayo FJ, Katzenellenbogen BS, Lydon JP, O'Malley BW. A repressive role for prohibitin in estrogen signaling. Mol Endocrinol. 2008 Feb; 22(2):344-60. PMID: 17932104.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    160. Mukherjee A, Soyal SM, Fernandez-Valdivia R, DeMayo FJ, Lydon JP. Targeting reverse tetracycline-dependent transactivator to murine mammary epithelial cells that express the progesterone receptor. Genesis. 2007 Oct; 45(10):639-46. PMID: 17941046.
      Citations: 7     Fields:    Translation:AnimalsCells
    161. Hiremath M, Lydon JP, Cowin P. The pattern of beta-catenin responsiveness within the mammary gland is regulated by progesterone receptor. Development. 2007 Oct; 134(20):3703-12. PMID: 17881490.
      Citations: 9     Fields:    Translation:AnimalsCells
    162. Lee KY, Jeong JW, Tsai SY, Lydon JP, DeMayo FJ. Mouse models of implantation. Trends Endocrinol Metab. 2007 Aug; 18(6):234-9. PMID: 17588769.
      Citations: 29     Fields:    Translation:Animals
    163. Jeong JW, Lee KY, Han SJ, Aronow BJ, Lydon JP, O'Malley BW, DeMayo FJ. The p160 steroid receptor coactivator 2, SRC-2, regulates murine endometrial function and regulates progesterone-independent and -dependent gene expression. Endocrinology. 2007 Sep; 148(9):4238-50. PMID: 17556502.
      Citations: 29     Fields:    Translation:Animals
    164. Satoh K, Hovey RC, Malewski T, Warri A, Goldhar AS, Ginsburg E, Saito K, Lydon JP, Vonderhaar BK. Progesterone enhances branching morphogenesis in the mouse mammary gland by increased expression of Msx2. Oncogene. 2007 Nov 29; 26(54):7526-34. PMID: 17546050.
      Citations: 19     Fields:    Translation:AnimalsCells
    165. Kurihara I, Lee DK, Petit FG, Jeong J, Lee K, Lydon JP, DeMayo FJ, Tsai MJ, Tsai SY. COUP-TFII mediates progesterone regulation of uterine implantation by controlling ER activity. PLoS Genet. 2007 Jun; 3(6):e102. PMID: 17590085.
      Citations: 88     Fields:    Translation:AnimalsCells
    166. Lee KY, Jeong JW, Wang J, Ma L, Martin JF, Tsai SY, Lydon JP, DeMayo FJ. Bmp2 is critical for the murine uterine decidual response. Mol Cell Biol. 2007 Aug; 27(15):5468-78. PMID: 17515606.
      Citations: 127     Fields:    Translation:HumansAnimalsCells
    167. Fernandez-Valdivia R, Mukherjee A, Amato P, Allred DC, Nguyen J, DeMayo FJ, Lydon JP. Progesterone-action in the murine uterus and mammary gland requires steroid receptor coactivator 2: relevance to the human. Front Biosci. 2007 May 01; 12:3640-7. PMID: 17485327.
      Citations: 5     Fields:    Translation:HumansAnimals
    168. Mukherjee A, Amato P, Craig-Allred D, DeMayo FJ, O'Malley BW, Lydon JP. Steroid receptor coactivator 2: an essential coregulator of progestin-induced uterine and mammary morphogenesis. Ernst Schering Found Symp Proc. 2007; (1):55-76. PMID: 18540568.
      Citations: 2     Fields:    Translation:HumansAnimals
    169. Mukherjee A, Soyal SM, Wheeler DA, Fernandez-Valdivia R, Nguyen J, DeMayo FJ, Lydon JP. Targeting iCre expression to murine progesterone receptor cell-lineages using bacterial artificial chromosome transgenesis. Genesis. 2006 Dec; 44(12):601-10. PMID: 17149722.
      Citations: 5     Fields:    Translation:AnimalsCells
    170. Lee K, Jeong J, Tsai MJ, Tsai S, Lydon JP, DeMayo FJ. Molecular mechanisms involved in progesterone receptor regulation of uterine function. J Steroid Biochem Mol Biol. 2006 Dec; 102(1-5):41-50. PMID: 17067792.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    171. Mukherjee A, Amato P, Allred DC, Fernandez-Valdivia R, Nguyen J, O'Malley BW, DeMayo FJ, Lydon JP. Steroid receptor coactivator 2 is essential for progesterone-dependent uterine function and mammary morphogenesis: insights from the mouse--implications for the human. J Steroid Biochem Mol Biol. 2006 Dec; 102(1-5):22-31. PMID: 17045797.
      Citations: 11     Fields:    Translation:HumansAnimals
    172. Roberts DP, McKenna LF, Hu X, Lohrke SM, Kong HS, de Souza JT, Baker CJ, Lydon J. Mutation in cyaA in Enterobacter cloacae decreases cucumber root colonization. Arch Microbiol. 2007 Feb; 187(2):101-15. PMID: 17024489.
      Citations: 4     Fields:    Translation:AnimalsCellsPHPublic Health
    173. Lee K, Jeong J, Kwak I, Yu CT, Lanske B, Soegiarto DW, Toftgard R, Tsai MJ, Tsai S, Lydon JP, DeMayo FJ. Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus. Nat Genet. 2006 Oct; 38(10):1204-9. PMID: 16951680.
      Citations: 110     Fields:    Translation:AnimalsCells
    174. Mukherjee A, Soyal SM, Fernandez-Valdivia R, Gehin M, Chambon P, Demayo FJ, Lydon JP, O'Malley BW. Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. Mol Cell Biol. 2006 Sep; 26(17):6571-83. PMID: 16914740.
      Citations: 55     Fields:    Translation:AnimalsCells
    175. Hashimoto-Partyka MK, Lydon JP, Iruela-Arispe ML. Generation of a mouse for conditional excision of progesterone receptor. Genesis. 2006 Aug; 44(8):391-5. PMID: 16868919.
      Citations: 7     Fields:    Translation:AnimalsCells
    176. Jeong JW, Lee KY, Lydon JP, DeMayo FJ. Steroid hormone regulation of Clca3 expression in the murine uterus. J Endocrinol. 2006 Jun; 189(3):473-84. PMID: 16731779.
      Citations: 9     Fields:    Translation:AnimalsCells
    177. Frye CA, Sumida K, Lydon JP, O'Malley BW, Pfaff DW. Mid-aged and aged wild-type and progestin receptor knockout (PRKO) mice demonstrate rapid progesterone and 3alpha,5alpha-THP-facilitated lordosis. Psychopharmacology (Berl). 2006 May; 185(4):423-32. PMID: 16544163.
      Citations: 23     Fields:    Translation:Animals
    178. Frye CA, Sumida K, Dudek BC, Harney JP, Lydon JP, O'Malley BW, Pfaff DW, Rhodes ME. Progesterone's effects to reduce anxiety behavior of aged mice do not require actions via intracellular progestin receptors. Psychopharmacology (Berl). 2006 Jun; 186(3):312-22. PMID: 16538472.
      Citations: 35     Fields:    Translation:Animals
    179. Woolley SC, O'Malley B, Lydon J, Crews D. Genotype differences in behavior and tyrosine hydroxylase expression between wild-type and progesterone receptor knockout mice. Behav Brain Res. 2006 Feb 28; 167(2):197-204. PMID: 16413068.
      Citations: 6     Fields:    Translation:Animals
    180. Schneider JS, Burgess C, Sleiter NC, DonCarlos LL, Lydon JP, O'Malley B, Levine JE. Enhanced sexual behaviors and androgen receptor immunoreactivity in the male progesterone receptor knockout mouse. Endocrinology. 2005 Oct; 146(10):4340-8. PMID: 16002522.
      Citations: 21     Fields:    Translation:Animals
    181. Jeong JW, Lee KY, Kwak I, White LD, Hilsenbeck SG, Lydon JP, DeMayo FJ. Identification of murine uterine genes regulated in a ligand-dependent manner by the progesterone receptor. Endocrinology. 2005 Aug; 146(8):3490-505. PMID: 15845616.
      Citations: 70     Fields:    Translation:Animals
    182. Soyal SM, Mukherjee A, Lee KY, Li J, Li H, DeMayo FJ, Lydon JP. Cre-mediated recombination in cell lineages that express the progesterone receptor. Genesis. 2005 Feb; 41(2):58-66. PMID: 15682389.
      Citations: 177     Fields:    Translation:Animals
    183. Fernandez-Valdivia R, Mukherjee A, Mulac-Jericevic B, Conneely OM, DeMayo FJ, Amato P, Lydon JP. Revealing progesterone's role in uterine and mammary gland biology: insights from the mouse. Semin Reprod Med. 2005 Feb; 23(1):22-37. PMID: 15714387.
      Citations: 28     Fields:    Translation:Animals
    184. Fang Z, Yang S, Lydon JP, DeMayo F, Tamura M, Gurates B, Bulun SE. Intact progesterone receptors are essential to counteract the proliferative effect of estradiol in a genetically engineered mouse model of endometriosis. Fertil Steril. 2004 Sep; 82(3):673-8. PMID: 15374713.
      Citations: 20     Fields:    Translation:Animals
    185. Shi HY, Lydon JP, Zhang M. Hormonal defect in maspin heterozygous mice reveals a role of progesterone in pubertal ductal development. Mol Endocrinol. 2004 Sep; 18(9):2196-207. PMID: 15178746.
      Citations: 6     Fields:    Translation:AnimalsCells
    186. Ismail PM, DeMayo FJ, Amato P, Lydon JP. Progesterone induction of calcitonin expression in the murine mammary gland. J Endocrinol. 2004 Feb; 180(2):287-95. PMID: 14765981.
      Citations: 13     Fields:    Translation:AnimalsCells
    187. Conneely OM, Mulac-Jericevic B, Lydon JP. Progesterone-dependent regulation of female reproductive activity by two distinct progesterone receptor isoforms. Steroids. 2003 Nov; 68(10-13):771-8. PMID: 14667967.
      Citations: 64     Fields:    Translation:HumansAnimals
    188. Ismail PM, Amato P, Soyal SM, DeMayo FJ, Conneely OM, O'Malley BW, Lydon JP. Progesterone involvement in breast development and tumorigenesis--as revealed by progesterone receptor "knockout" and "knockin" mouse models. Steroids. 2003 Nov; 68(10-13):779-87. PMID: 14667968.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    189. Mulac-Jericevic B, Lydon JP, DeMayo FJ, Conneely OM. Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform. Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17):9744-9. PMID: 12897242.
      Citations: 199     Fields:    Translation:AnimalsCells
    190. Conneely OM, Jericevic BM, Lydon JP. Progesterone receptors in mammary gland development and tumorigenesis. J Mammary Gland Biol Neoplasia. 2003 Apr; 8(2):205-14. PMID: 14635795.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    191. Medina D, Kittrell FS, Shepard A, Contreras A, Rosen JM, Lydon J. Hormone dependence in premalignant mammary progression. Cancer Res. 2003 Mar 01; 63(5):1067-72. PMID: 12615724.
      Citations: 37     Fields:    Translation:Animals
    192. Schneider JS, Stone MK, Wynne-Edwards KE, Horton TH, Lydon J, O'Malley B, Levine JE. Progesterone receptors mediate male aggression toward infants. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2951-6. PMID: 12601162.
      Citations: 30     Fields:    Translation:Animals
    193. Chatterton RT, Lydon JP, Mehta RG, Mateo ET, Pletz A, Jordan VC. Role of the progesterone receptor (PR) in susceptibility of mouse mammary gland to 7,12-dimethylbenz[a]anthracene-induced hormone-independent preneoplastic lesions in vitro. Cancer Lett. 2002 Dec 15; 188(1-2):47-52. PMID: 12406547.
      Citations: 10     Fields:    Translation:Animals
    194. Grimm SL, Seagroves TN, Kabotyanski EB, Hovey RC, Vonderhaar BK, Lydon JP, Miyoshi K, Hennighausen L, Ormandy CJ, Lee AV, Stull MA, Wood TL, Rosen JM. Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development. Mol Endocrinol. 2002 Dec; 16(12):2675-91. PMID: 12456789.
      Citations: 49     Fields:    Translation:AnimalsCells
    195. Picard F, Wanatabe M, Schoonjans K, Lydon J, O'Malley BW, Auwerx J. Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation. Proc Natl Acad Sci U S A. 2002 Nov 26; 99(24):15644-8. PMID: 12438645.
      Citations: 40     Fields:    Translation:AnimalsCells
    196. Ismail PM, Li J, DeMayo FJ, O'Malley BW, Lydon JP. A novel LacZ reporter mouse reveals complex regulation of the progesterone receptor promoter during mammary gland development. Mol Endocrinol. 2002 Nov; 16(11):2475-89. PMID: 12403837.
      Citations: 55     Fields:    Translation:AnimalsCells
    197. Mills DJ, Coffman CB, Teasdale JR, Everts KL, Abdul-Baki AA, Lydon J, Anderson JD. Foliar Disease in Fresh-Market Tomato Grown in Differing Bed Strategies and Fungicide Spray Programs. Plant Dis. 2002 Sep; 86(9):955-959. PMID: 30818555.
      Citations:    Fields:    
    198. Soyal S, Ismail PM, Li J, Mulac-Jericevic B, Conneely OM, Lydon JP. Progesterone's role in mammary gland development and tumorigenesis as disclosed by experimental mouse genetics. Breast Cancer Res. 2002; 4(5):191-6. PMID: 12223123.
      Citations: 15     Fields:    Translation:Animals
    199. Conneely OM, Mulac-Jericevic B, DeMayo F, Lydon JP, O'Malley BW. Reproductive functions of progesterone receptors. Recent Prog Horm Res. 2002; 57:339-55. PMID: 12017551.
      Citations: 82     Fields:    Translation:HumansAnimals
    200. Karas RH, van Eickels M, Lydon JP, Roddy S, Kwoun M, Aronovitz M, Baur WE, Conneely O, O'Malley BW, Mendelsohn ME. A complex role for the progesterone receptor in the response to vascular injury. J Clin Invest. 2001 Aug; 108(4):611-8. PMID: 11518735.
      Citations: 7     Fields:    Translation:AnimalsCells
    201. Conneely OM, Mulac-Jericevic B, Lydon JP, De Mayo FJ. Reproductive functions of the progesterone receptor isoforms: lessons from knock-out mice. Mol Cell Endocrinol. 2001 Jun 20; 179(1-2):97-103. PMID: 11420134.
      Citations: 59     Fields:    Translation:Animals
    202. Kurita T, Wang YZ, Donjacour AA, Zhao C, Lydon JP, O'Malley BW, Isaacs JT, Dahiya R, Cunha GR. Paracrine regulation of apoptosis by steroid hormones in the male and female reproductive system. Cell Death Differ. 2001 Feb; 8(2):192-200. PMID: 11313721.
      Citations: 47     Fields:    Translation:AnimalsCells
    203. Krebs CJ, Jarvis ED, Chan J, Lydon JP, Ogawa S, Pfaff DW. A membrane-associated progesterone-binding protein, 25-Dx, is regulated by progesterone in brain regions involved in female reproductive behaviors. Proc Natl Acad Sci U S A. 2000 Nov 07; 97(23):12816-21. PMID: 11070092.
      Citations: 60     Fields:    Translation:AnimalsCells
    204. Robker RL, Russell DL, Yoshioka S, Sharma SC, Lydon JP, O'Malley BW, Espey LL, Richards JS. Ovulation: a multi-gene, multi-step process. Steroids. 2000 Oct-Nov; 65(10-11):559-70. PMID: 11108860.
      Citations: 26     Fields:    Translation:AnimalsCells
    205. Conneely OM, Lydon JP. Progesterone receptors in reproduction: functional impact of the A and B isoforms. Steroids. 2000 Oct-Nov; 65(10-11):571-7. PMID: 11108861.
      Citations: 40     Fields:    Translation:HumansAnimals
    206. Mulac-Jericevic B, Mullinax RA, DeMayo FJ, Lydon JP, Conneely OM. Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform. Science. 2000 Sep 08; 289(5485):1751-4. PMID: 10976068.
      Citations: 164     Fields:    Translation:AnimalsCells
    207. Lydon JP, Sivaraman L, Conneely OM. A reappraisal of progesterone action in the mammary gland. J Mammary Gland Biol Neoplasia. 2000 Jul; 5(3):325-38. PMID: 14973394.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    208. Robker RL, Russell DL, Espey LL, Lydon JP, O'Malley BW, Richards JS. Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases. Proc Natl Acad Sci U S A. 2000 Apr 25; 97(9):4689-94. PMID: 10781075.
      Citations: 106     Fields:    Translation:AnimalsCells
    209. Kurita T, Lee KJ, Cooke PS, Lydon JP, Cunha GR. Paracrine regulation of epithelial progesterone receptor and lactoferrin by progesterone in the mouse uterus. Biol Reprod. 2000 Apr; 62(4):831-8. PMID: 10727250.
      Citations: 28     Fields:    Translation:AnimalsCells
    210. Seagroves TN, Lydon JP, Hovey RC, Vonderhaar BK, Rosen JM. C/EBPbeta (CCAAT/enhancer binding protein) controls cell fate determination during mammary gland development. Mol Endocrinol. 2000 Mar; 14(3):359-68. PMID: 10707954.
      Citations: 72     Fields:    Translation:AnimalsCells
    211. Conneely OM, Lydon JP, De Mayo F, O'Malley BW. Reproductive functions of the progesterone receptor. J Soc Gynecol Investig. 2000 Jan-Feb; 7(1 Suppl):S25-32. PMID: 10732326.
      Citations: 15     Fields:    Translation:HumansAnimals
    212. Lydon JP, Ge G, Kittrell FS, Medina D, O'Malley BW. Murine mammary gland carcinogenesis is critically dependent on progesterone receptor function. Cancer Res. 1999 Sep 01; 59(17):4276-84. PMID: 10485472.
      Citations: 63     Fields:    Translation:Animals
    213. Chappell PE, Schneider JS, Kim P, Xu M, Lydon JP, O'Malley BW, Levine JE. Absence of gonadotropin surges and gonadotropin-releasing hormone self-priming in ovariectomized (OVX), estrogen (E2)-treated, progesterone receptor knockout (PRKO) mice. Endocrinology. 1999 Aug; 140(8):3653-8. PMID: 10433223.
      Citations: 46     Fields:    Translation:Animals
    214. Vázquez F, Rodríguez-Manzaneque JC, Lydon JP, Edwards DP, O'Malley BW, Iruela-Arispe ML. Progesterone regulates proliferation of endothelial cells. J Biol Chem. 1999 Jan 22; 274(4):2185-92. PMID: 9890981.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    215. Phelps SM, Lydon JP, O'malley BW, Crews D. Regulation of male sexual behavior by progesterone receptor, sexual experience, and androgen. Horm Behav. 1998 Dec; 34(3):294-302. PMID: 9878278.
      Citations: 16     Fields:    Translation:Animals
    216. Kurita T, Young P, Brody JR, Lydon JP, O'Malley BW, Cunha GR. Stromal progesterone receptors mediate the inhibitory effects of progesterone on estrogen-induced uterine epithelial cell deoxyribonucleic acid synthesis. Endocrinology. 1998 Nov; 139(11):4708-13. PMID: 9794483.
      Citations: 60     Fields:    Translation:AnimalsCells
    217. Brisken C, Park S, Vass T, Lydon JP, O'Malley BW, Weinberg RA. A paracrine role for the epithelial progesterone receptor in mammary gland development. Proc Natl Acad Sci U S A. 1998 Apr 28; 95(9):5076-81. PMID: 9560231.
      Citations: 159     Fields:    Translation:Animals
    218. Humphreys RC, Lydon JP, O'Malley BW, Rosen JM. Use of PRKO mice to study the role of progesterone in mammary gland development. J Mammary Gland Biol Neoplasia. 1997 Oct; 2(4):343-54. PMID: 10935022.
      Citations: 27     Fields:    Translation:Animals
    219. Chappell PE, Lydon JP, Conneely OM, O'Malley BW, Levine JE. Endocrine defects in mice carrying a null mutation for the progesterone receptor gene. Endocrinology. 1997 Oct; 138(10):4147-52. PMID: 9322923.
      Citations: 40     Fields:    Translation:Animals
    220. Said TK, Conneely OM, Medina D, O'Malley BW, Lydon JP. Progesterone, in addition to estrogen, induces cyclin D1 expression in the murine mammary epithelial cell, in vivo. Endocrinology. 1997 Sep; 138(9):3933-9. PMID: 9275084.
      Citations: 33     Fields:    Translation:AnimalsCells
    221. Qiu Y, Pereira FA, DeMayo FJ, Lydon JP, Tsai SY, Tsai MJ. Null mutation of mCOUP-TFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization. Genes Dev. 1997 Aug 01; 11(15):1925-37. PMID: 9271116.
      Citations: 72     Fields:    Translation:AnimalsCells
    222. Humphreys RC, Lydon J, O'Malley BW, Rosen JM. Mammary gland development is mediated by both stromal and epithelial progesterone receptors. Mol Endocrinol. 1997 Jun; 11(6):801-11. PMID: 9171243.
      Citations: 50     Fields:    Translation:AnimalsCells
    223. Saucedo-Cardenas O, Kardon R, Ediger TR, Lydon JP, Conneely OM. Cloning and structural organization of the gene encoding the murine nuclear receptor transcription factor, NURR1. Gene. 1997 Mar 10; 187(1):135-9. PMID: 9073077.
      Citations: 20     Fields:    Translation:AnimalsCells
    224. Mani SK, Allen JM, Lydon JP, Mulac-Jericevic B, Blaustein JD, DeMayo FJ, Conneely O, O'Malley BW. Dopamine requires the unoccupied progesterone receptor to induce sexual behavior in mice. Mol Endocrinol. 1996 Dec; 10(12):1728-37. PMID: 8961281.
      Citations: 44     Fields:    Translation:AnimalsCells
    225. Lydon JP, DeMayo FJ, Conneely OM, O'Malley BW. Reproductive phenotpes of the progesterone receptor null mutant mouse. J Steroid Biochem Mol Biol. 1996 Jan; 56(1-6 Spec No):67-77. PMID: 8603049.
      Citations: 59     Fields:    Translation:Animals
    226. Lydon JP, DeMayo FJ, Funk CR, Mani SK, Hughes AR, Montgomery CA, Shyamala G, Conneely OM, O'Malley BW. Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev. 1995 Sep 15; 9(18):2266-78. PMID: 7557380.
      Citations: 483     Fields:    Translation:Animals
    227. Lydon JP, O'Malley BR, Saucedo O, Lee T, Headon DR, Conneely OM. Nucleotide and primary amino acid sequence of porcine lactoferrin. Biochim Biophys Acta. 1992 Aug 17; 1132(1):97-9. PMID: 1511016.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    228. Lydon JP, Power RF, Conneely OM. Differential modes of activation define orphan subclasses within the steroid/thyroid receptor superfamily. Gene Expr. 1992; 2(3):273-83. PMID: 1450665.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    229. Power RF, Lydon JP, Conneely OM, O'Malley BW. Dopamine activation of an orphan of the steroid receptor superfamily. Science. 1991 Jun 14; 252(5012):1546-8. PMID: 2047861.
      Citations: 44     Fields:    Translation:AnimalsCells
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