SOPHIA TSAI

TitleDistinguished Emeritus Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleDistinguished Emeritus Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Medicine
    DivisionMedicine-Endocrinology


    Collapse Overview 

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    R01DK044988     (TSAI, SOPHIA Y)Jan 1, 1993 - Jun 30, 1999
    NIH
    HORMONE REGULATED EXPRESSION OF INSULIN RECEPTOR GENE
    Role: Principal Investigator

    R01DK055636     (TSAI, SOPHIA Y)Jun 1, 1999 - Apr 30, 2005
    NIH
    PHYSIOLOGICAL ROLE OF A NUCLEAR ORPHAN RECEPTOR COUP TFIl
    Role: Principal Investigator

    R01DK065264     (TSAI, SOPHIA Y)Aug 1, 2003 - May 31, 2007
    NIH
    AR Coactivators, Mechanisms &Roles in Prostate Cancer
    Role: Principal Investigator

    R01HL076448     (TSAI, SOPHIA Y.)Apr 1, 2004 - Jun 30, 2014
    NIH
    A Nuclear Receptor COUP-TFII in Vascular Function: Angiogenesis and Tumoirgenesis
    Role: Principal Investigator

    R01HL114539     (TSAI, SOPHIA Y.)Jul 15, 2013 - Apr 30, 2019
    NIH
    Nuclear Orphan Receptor, COUP-TFII, in Energy Metabolism and Disease
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kao CY, Xu M, Wang L, Lin SC, Lee HJ, Duraine L, Bellen HJ, Goldstein DS, Tsai SY, Tsai MJ. Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson's disease through mitochondrial dysfunction. PLoS Genet. 2020 06; 16(6):e1008868. PMID: 32579581.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    2. Wu SY, Lee CF, Lai HT, Yu CT, Lee JE, Zuo H, Tsai SY, Tsai MJ, Ge K, Wan Y, Chiang CM. Opposing Functions of BRD4 Isoforms in Breast Cancer. Mol Cell. 2020 06 18; 78(6):1114-1132.e10. PMID: 32446320.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    3. Wang L, Cheng CM, Qin J, Xu M, Kao CY, Shi J, You E, Gong W, Rosa LP, Chase P, Scampavia L, Madoux F, Spicer T, Hodder P, Xu HE, Tsai SY, Tsai MJ. Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment. Sci Adv. 2020 05; 6(18):eaaz8031. PMID: 32494682.
      Citations: 4     Fields:    Translation:HumansAnimals
    4. Wang L, Xu M, Kao CY, Tsai SY, Tsai MJ. Small molecule JQ1 promotes prostate cancer invasion via BET-independent inactivation of FOXA1. J Clin Invest. 2020 04 01; 130(4):1782-1792. PMID: 31874106.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    5. Xu M, Qin J, Wang L, Lee HJ, Kao CY, Liu D, Songyang Z, Chen J, Tsai MJ, Tsai SY. Nuclear receptors regulate alternative lengthening of telomeres through a novel noncanonical FANCD2 pathway. Sci Adv. 2019 10; 5(10):eaax6366. PMID: 31633027.
      Citations: 11     Fields:    Translation:HumansCells
    6. Panigrahi AK, Foulds CE, Lanz RB, Hamilton RA, Yi P, Lonard DM, Tsai MJ, Tsai SY, O'Malley BW. SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription. Mol Cell. 2018 05 17; 70(4):679-694.e7. PMID: 29775582.
      Citations: 17     Fields:    Translation:HumansCells
    7. Dasgupta S, Rajapakshe K, Zhu B, Nikolai BC, Yi P, Putluri N, Choi JM, Jung SY, Coarfa C, Westbrook TF, Zhang XH, Foulds CE, Tsai SY, Tsai MJ, O'Malley BW. Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer. Nature. 2018 04; 556(7700):249-254. PMID: 29615789.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    8. Zhao F, Franco HL, Rodriguez KF, Brown PR, Tsai MJ, Tsai SY, Yao HH. Elimination of the male reproductive tract in the female embryo is promoted by COUP-TFII in mice. Science. 2017 08 18; 357(6352):717-720. PMID: 28818950.
      Citations: 28     Fields:    Translation:AnimalsCells
    9. Gates LA, Shi J, Rohira AD, Feng Q, Zhu B, Bedford MT, Sagum CA, Jung SY, Qin J, Tsai MJ, Tsai SY, Li W, Foulds CE, O'Malley BW. Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation. J Biol Chem. 2017 09 01; 292(35):14456-14472. PMID: 28717009.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    10. Lee HJ, Kao CY, Lin SC, Xu M, Xie X, Tsai SY, Tsai MJ. Dysregulation of nuclear receptor COUP-TFII impairs skeletal muscle development. Sci Rep. 2017 06 09; 7(1):3136. PMID: 28600496.
      Citations: 15     Fields:    Translation:AnimalsCells
    11. Wetendorf M, Wu SP, Wang X, Creighton CJ, Wang T, Lanz RB, Blok L, Tsai SY, Tsai MJ, Lydon JP, DeMayo FJ. Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment. Biol Reprod. 2017 02 01; 96(2):313-326. PMID: 28203817.
      Citations: 27     Fields:    Translation:AnimalsCells
    12. Xie X, Wu SP, Tsai MJ, Tsai S. The Role of COUP-TFII in Striated Muscle Development and Disease. Curr Top Dev Biol. 2017; 125:375-403. PMID: 28527579.
      Citations: 3     Fields:    Translation:HumansAnimals
    13. Forrest D, Tsai S. Preface. Curr Top Dev Biol. 2017; 125:xv-xvi. PMID: 28527582.
      Citations:    Fields:    Translation:HumansAnimals
    14. Xie X, Tsai SY, Tsai MJ. COUP-TFII regulates satellite cell function and muscular dystrophy. J Clin Invest. 2016 10 03; 126(10):3929-3941. PMID: 27617862.
      Citations: 16     Fields:    Translation:AnimalsCells
    15. Lin SC, Kao CY, Lee HJ, Creighton CJ, Ittmann MM, Tsai SJ, Tsai SY, Tsai MJ. Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer. Nat Commun. 2016 04 25; 7:11418. PMID: 27108958.
      Citations: 54     Fields:    Translation:HumansAnimals
    16. Vasquez YM, Wu SP, Anderson ML, Hawkins SM, Creighton CJ, Ray M, Tsai SY, Tsai MJ, Lydon JP, DeMayo FJ. Endometrial Expression of Steroidogenic Factor 1 Promotes Cystic Glandular Morphogenesis. Mol Endocrinol. 2016 May; 30(5):518-32. PMID: 27018534.
      Citations: 10     Fields:    Translation:AnimalsCells
    17. Wang L, Xu M, Qin J, Lin SC, Lee HJ, Tsai SY, Tsai MJ. MPC1, a key gene in cancer metabolism, is regulated by COUPTFII in human prostate cancer. Oncotarget. 2016 Mar 22; 7(12):14673-83. PMID: 26895100.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    18. Wu SP, Yu CT, Tsai SY, Tsai MJ. Choose your destiny: Make a cell fate decision with COUP-TFII. J Steroid Biochem Mol Biol. 2016 Mar; 157:7-12. PMID: 26658017.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    19. Szwarc MM, Kommagani R, Jeong JW, Wu SP, Tsai SY, Tsai MJ, O'Malley BW, DeMayo FJ, Lydon JP. Correction: Perturbing the Cellular Levels of Steroid Receptor Coactivator-2 Impairs Murine Endometrial Function. PLoS One. 2015; 10(11):e0143652. PMID: 26580555.
      Citations:    Fields:    
    20. Han SJ, Jung SY, Wu SP, Hawkins SM, Park MJ, Kyo S, Qin J, Lydon JP, Tsai SY, Tsai MJ, DeMayo FJ, O'Malley BW. Estrogen Receptor ß Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis. Cell. 2015 Nov 05; 163(4):960-74. PMID: 26544941.
      Citations: 100     Fields:    Translation:HumansAnimals
    21. Wu SP, Kao CY, Wang L, Creighton CJ, Yang J, Donti TR, Harmancey R, Vasquez HG, Graham BH, Bellen HJ, Taegtmeyer H, Chang CP, Tsai MJ, Tsai SY. Increased COUP-TFII expression in adult hearts induces mitochondrial dysfunction resulting in heart failure. Nat Commun. 2015 Sep 10; 6:8245. PMID: 26356605.
      Citations: 33     Fields:    Translation:AnimalsCells
    22. Xu P, Cao X, He Y, Zhu L, Yang Y, Saito K, Wang C, Yan X, Hinton AO, Zou F, Ding H, Xia Y, Yan C, Shu G, Wu SP, Yang B, Feng Y, Clegg DJ, DeMarchi R, Khan SA, Tsai SY, DeMayo FJ, Wu Q, Tong Q, Xu Y. Estrogen receptor-a in medial amygdala neurons regulates body weight. J Clin Invest. 2015 Jul 01; 125(7):2861-76. PMID: 26098212.
      Citations: 53     Fields:    Translation:AnimalsCells
    23. Kang YK, Putluri N, Maity S, Tsimelzon A, Ilkayeva O, Mo Q, Lonard D, Michailidis G, Sreekumar A, Newgard CB, Wang M, Tsai SY, Tsai MJ, O'Malley BW. CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-a-Gabpa and stress-induced adaptive responses via NF-?B-cMYC. PLoS Genet. 2015 Apr; 11(4):e1005116. PMID: 25830341.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    24. Qin J, Lee HJ, Wu SP, Lin SC, Lanz RB, Creighton CJ, DeMayo FJ, Tsai SY, Tsai MJ. Androgen deprivation-induced NCoA2 promotes metastatic and castration-resistant prostate cancer. J Clin Invest. 2014 Nov; 124(11):5013-26. PMID: 25295534.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    25. Xu M, Qin J, Tsai SY, Tsai MJ. The role of the orphan nuclear receptor COUP-TFII in tumorigenesis. Acta Pharmacol Sin. 2015 Jan; 36(1):32-6. PMID: 25283503.
      Citations: 15     Fields:    Translation:HumansAnimals
    26. Qin J, Tsai SY, Tsai MJ. The critical roles of COUP-TFII in tumor progression and metastasis. Cell Biosci. 2014; 4(1):58. PMID: 25328664.
      Citations: 15     
    27. Szwarc MM, Kommagani R, Jeong JW, Wu SP, Tsai SY, Tsai MJ, O'Malley BW, DeMayo FJ, Lydon JP. Perturbing the cellular levels of steroid receptor coactivator-2 impairs murine endometrial function. PLoS One. 2014; 9(6):e98664. PMID: 24905738.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    28. Tang K, Tsai SY, Tsai MJ. COUP-TFs and eye development. Biochim Biophys Acta. 2015 Feb; 1849(2):201-9. PMID: 24878540.
      Citations: 16     Fields:    Translation:HumansAnimals
    29. Kang YK, Jung SY, Qin J, Li C, Tsai SY, Tsai MJ, O'Malley BW. E2/Estrogen receptor/sjogren syndrome-associated autoantigen relieves coactivator activator-induced G1/S arrest to promote breast tumorigenicity. Mol Cell Biol. 2014 May; 34(9):1670-81. PMID: 24567374.
      Citations: 2     Fields:    Translation:HumansCells
    30. Bosch DG, Boonstra FN, Gonzaga-Jauregui C, Xu M, de Ligt J, Jhangiani S, Wiszniewski W, Muzny DM, Yntema HG, Pfundt R, Vissers LE, Spruijt L, Blokland EA, Chen CA, Lewis RA, Tsai SY, Gibbs RA, Tsai MJ, Lupski JR, Zoghbi HY, Cremers FP, de Vries BB, Schaaf CP. NR2F1 mutations cause optic atrophy with intellectual disability. Am J Hum Genet. 2014 Feb 06; 94(2):303-9. PMID: 24462372.
      Citations: 39     Fields:    Translation:HumansCells
    31. Lin SC, Li YH, Wu MH, Chang YF, Lee DK, Tsai SY, Tsai MJ, Tsai SJ. Suppression of COUP-TFII by proinflammatory cytokines contributes to the pathogenesis of endometriosis. J Clin Endocrinol Metab. 2014 Mar; 99(3):E427-37. PMID: 24423359.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    32. Li X, Large MJ, Creighton CJ, Lanz RB, Jeong JW, Young SL, Lessey BA, Palomino WA, Tsai SY, Demayo FJ. COUP-TFII regulates human endometrial stromal genes involved in inflammation. Mol Endocrinol. 2013 Dec; 27(12):2041-54. PMID: 24176914.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    33. Xie X, Tang K, Yu CT, Tsai SY, Tsai MJ. Regulatory potential of COUP-TFs in development: stem/progenitor cells. Semin Cell Dev Biol. 2013 Dec; 24(10-12):687-93. PMID: 23978678.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    34. Foulds CE, Feng Q, Ding C, Bailey S, Hunsaker TL, Malovannaya A, Hamilton RA, Gates LA, Zhang Z, Li C, Chan D, Bajaj A, Callaway CG, Edwards DP, Lonard DM, Tsai SY, Tsai MJ, Qin J, O'Malley BW. Proteomic analysis of coregulators bound to ERa on DNA and nucleosomes reveals coregulator dynamics. Mol Cell. 2013 Jul 25; 51(2):185-99. PMID: 23850489.
      Citations: 73     Fields:    Translation:HumansCells
    35. Wu SP, Cheng CM, Lanz RB, Wang T, Respress JL, Ather S, Chen W, Tsai SJ, Wehrens XH, Tsai MJ, Tsai SY. Atrial identity is determined by a COUP-TFII regulatory network. Dev Cell. 2013 May 28; 25(4):417-26. PMID: 23725765.
      Citations: 57     Fields:    Translation:AnimalsCells
    36. Qin J, Tsai S, Tsai MJ. COUP-TFII, a prognostic marker and therapeutic target for prostate cancer. Asian J Androl. 2013 May; 15(3):360-1. PMID: 23435470.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    37. Qin J, Wu SP, Creighton CJ, Dai F, Xie X, Cheng CM, Frolov A, Ayala G, Lin X, Feng XH, Ittmann MM, Tsai SJ, Tsai MJ, Tsai SY. COUP-TFII inhibits TGF-ß-induced growth barrier to promote prostate tumorigenesis. Nature. 2013 Jan 10; 493(7431):236-40. PMID: 23201680.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    38. Lin FJ, You LR, Yu CT, Hsu WH, Tsai MJ, Tsai SY. Endocardial cushion morphogenesis and coronary vessel development require chicken ovalbumin upstream promoter-transcription factor II. Arterioscler Thromb Vasc Biol. 2012 Nov; 32(11):e135-46. PMID: 22962329.
      Citations: 24     Fields:    Translation:Animals
    39. Yu CT, Tang K, Suh JM, Jiang R, Tsai SY, Tsai MJ. COUP-TFII is essential for metanephric mesenchyme formation and kidney precursor cell survival. Development. 2012 Jul; 139(13):2330-9. PMID: 22669823.
      Citations: 21     Fields:    Translation:AnimalsCells
    40. Chen X, Qin J, Cheng CM, Tsai MJ, Tsai SY. COUP-TFII is a major regulator of cell cycle and Notch signaling pathways. Mol Endocrinol. 2012 Aug; 26(8):1268-77. PMID: 22734039.
      Citations: 33     Fields:    Translation:HumansCells
    41. Mayer S, Roeser M, Lachmann P, Ishii S, Suh JM, Harlander S, Desch M, Brunssen C, Morawietz H, Tsai SY, Tsai MJ, Hohenstein B, Hugo C, Todorov VT. Chicken ovalbumin upstream promoter transcription factor II regulates renin gene expression. J Biol Chem. 2012 Jul 13; 287(29):24483-91. PMID: 22645148.
      Citations: 7     Fields:    Translation:AnimalsCells
    42. Tang K, Rubenstein JL, Tsai SY, Tsai MJ. COUP-TFII controls amygdala patterning by regulating neuropilin expression. Development. 2012 May; 139(9):1630-9. PMID: 22492355.
      Citations: 24     Fields:    Translation:Animals
    43. Long W, Foulds CE, Qin J, Liu J, Ding C, Lonard DM, Solis LM, Wistuba II, Qin J, Tsai SY, Tsai MJ, O'Malley BW. ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion. J Clin Invest. 2012 May; 122(5):1869-80. PMID: 22505454.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    44. Xie X, Qin J, Lin SH, Tsai SY, Tsai MJ. Nuclear receptor chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) modulates mesenchymal cell commitment and differentiation. Proc Natl Acad Sci U S A. 2011 Sep 06; 108(36):14843-8. PMID: 21873211.
      Citations: 33     Fields:    Translation:AnimalsCells
    45. Lin FJ, Qin J, Tang K, Tsai SY, Tsai MJ. Coup d'Etat: an orphan takes control. Endocr Rev. 2011 Jun; 32(3):404-21. PMID: 21257780.
      Citations: 80     Fields:    Translation:Animals
    46. Qin J, Chen X, Yu-Lee LY, Tsai MJ, Tsai SY. Nuclear receptor COUP-TFII controls pancreatic islet tumor angiogenesis by regulating vascular endothelial growth factor/vascular endothelial growth factor receptor-2 signaling. Cancer Res. 2010 Nov 01; 70(21):8812-21. PMID: 20978203.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    47. Wu SP, Lee DK, Demayo FJ, Tsai SY, Tsai MJ. Generation of ES cells for conditional expression of nuclear receptors and coregulators in vivo. Mol Endocrinol. 2010 Jun; 24(6):1297-304. PMID: 20382891.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    48. Lin FJ, Chen X, Qin J, Hong YK, Tsai MJ, Tsai SY. Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development. J Clin Invest. 2010 May; 120(5):1694-707. PMID: 20364082.
      Citations: 67     Fields:    Translation:AnimalsCells
    49. Foulds CE, Tsimelzon A, Long W, Le A, Tsai SY, Tsai MJ, O'Malley BW. Research resource: expression profiling reveals unexpected targets and functions of the human steroid receptor RNA activator (SRA) gene. Mol Endocrinol. 2010 May; 24(5):1090-105. PMID: 20219889.
      Citations: 30     Fields:    Translation:HumansCells
    50. Lee DK, Kurihara I, Jeong JW, Lydon JP, DeMayo FJ, Tsai MJ, Tsai SY. Suppression of ERalpha activity by COUP-TFII is essential for successful implantation and decidualization. Mol Endocrinol. 2010 May; 24(5):930-40. PMID: 20219888.
      Citations: 40     Fields:    Translation:Animals
    51. Tang K, Xie X, Park JI, Jamrich M, Tsai S, Tsai MJ. COUP-TFs regulate eye development by controlling factors essential for optic vesicle morphogenesis. Development. 2010 Mar; 137(5):725-34. PMID: 20147377.
      Citations: 61     Fields:    Translation:AnimalsCells
    52. Long W, Yi P, Amazit L, LaMarca HL, Ashcroft F, Kumar R, Mancini MA, Tsai SY, Tsai MJ, O'Malley BW. SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell. 2010 Feb 12; 37(3):321-32. PMID: 20159552.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    53. Qin J, Chen X, Xie X, Tsai MJ, Tsai SY. COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3687-92. PMID: 20133706.
      Citations: 59     Fields:    Translation:Animals
    54. Rubel CA, Jeong JW, Tsai SY, Lydon JP, Demayo FJ. Epithelial-stromal interaction and progesterone receptors in the mouse uterus. Semin Reprod Med. 2010 Jan; 28(1):27-35. PMID: 20104426.
      Citations: 28     Fields:    Translation:AnimalsCells
    55. Feng Q, He B, Jung SY, Song Y, Qin J, Tsai SY, Tsai MJ, O'Malley BW. Biochemical control of CARM1 enzymatic activity by phosphorylation. J Biol Chem. 2009 Dec 25; 284(52):36167-36174. PMID: 19843527.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    56. Satoh S, Tang K, Iida A, Inoue M, Kodama T, Tsai SY, Tsai MJ, Furuta Y, Watanabe S. The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors. J Neurosci. 2009 Oct 07; 29(40):12401-11. PMID: 19812316.
      Citations: 37     Fields:    Translation:AnimalsCells
    57. Jeong JW, Lee HS, Lee KY, White LD, Broaddus RR, Zhang YW, Vande Woude GF, Giudice LC, Young SL, Lessey BA, Tsai SY, Lydon JP, DeMayo FJ. Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease. Proc Natl Acad Sci U S A. 2009 May 26; 106(21):8677-82. PMID: 19439667.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    58. McKenna NJ, Cooney AJ, DeMayo FJ, Downes M, Glass CK, Lanz RB, Lazar MA, Mangelsdorf DJ, Moore DD, Qin J, Steffen DL, Tsai MJ, Tsai SY, Yu R, Margolis RN, Evans RM, O'Malley BW. Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol. 2009 Jun; 23(6):740-6. PMID: 19423650.
      Citations: 61     Fields:    Translation:Cells
    59. Ngan ES, Lang BH, Liu T, Shum CK, So MT, Lau DK, Leon TY, Cherny SS, Tsai SY, Lo CY, Khoo US, Tam PK, Garcia-Barceló MM. A germline mutation (A339V) in thyroid transcription factor-1 (TITF-1/NKX2.1) in patients with multinodular goiter and papillary thyroid carcinoma. J Natl Cancer Inst. 2009 Feb 04; 101(3):162-75. PMID: 19176457.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    60. Li L, Xie X, Qin J, Jeha GS, Saha PK, Yan J, Haueter CM, Chan L, Tsai SY, Tsai MJ. The nuclear orphan receptor COUP-TFII plays an essential role in adipogenesis, glucose homeostasis, and energy metabolism. Cell Metab. 2009 Jan 07; 9(1):77-87. PMID: 19117548.
      Citations: 61     Fields:    Translation:AnimalsCells
    61. Kim BJ, Takamoto N, Yan J, Tsai SY, Tsai MJ. Chicken Ovalbumin Upstream Promoter-Transcription Factor II (COUP-TFII) regulates growth and patterning of the postnatal mouse cerebellum. Dev Biol. 2009 Feb 15; 326(2):378-91. PMID: 19041640.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    62. Kang YK, Schiff R, Ko L, Wang T, Tsai SY, Tsai MJ, O'Malley BW. Dual roles for coactivator activator and its counterbalancing isoform coactivator modulator in human kidney cell tumorigenesis. Cancer Res. 2008 Oct 01; 68(19):7887-96. PMID: 18829545.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    63. Li C, Liang YY, Feng XH, Tsai SY, Tsai MJ, O'Malley BW. Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. Mol Cell. 2008 Sep 26; 31(6):835-49. PMID: 18922467.
      Citations: 39     Fields:    Translation:HumansCells
    64. Qin J, Tsai MJ, Tsai SY. Essential roles of COUP-TFII in Leydig cell differentiation and male fertility. PLoS One. 2008 Sep 26; 3(9):e3285. PMID: 18818749.
      Citations: 43     Fields:    Translation:AnimalsCells
    65. Jeong JW, Lee HS, Franco HL, Broaddus RR, Taketo MM, Tsai SY, Lydon JP, DeMayo FJ. beta-catenin mediates glandular formation and dysregulation of beta-catenin induces hyperplasia formation in the murine uterus. Oncogene. 2009 Jan 08; 28(1):31-40. PMID: 18806829.
      Citations: 96     Fields:    Translation:Animals
    66. Kruse SW, Suino-Powell K, Zhou XE, Kretschman JE, Reynolds R, Vonrhein C, Xu Y, Wang L, Tsai SY, Tsai MJ, Xu HE. Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor. PLoS Biol. 2008 Sep 16; 6(9):e227. PMID: 18798693.
      Citations: 108     Fields:    Translation:HumansAnimalsCells
    67. Yan J, Erdem H, Li R, Cai Y, Ayala G, Ittmann M, Yu-Lee LY, Tsai SY, Tsai MJ. Steroid receptor coactivator-3/AIB1 promotes cell migration and invasiveness through focal adhesion turnover and matrix metalloproteinase expression. Cancer Res. 2008 Jul 01; 68(13):5460-8. PMID: 18593949.
      Citations: 61     Fields:    Translation:HumansCells
    68. Yi P, Feng Q, Amazit L, Lonard DM, Tsai SY, Tsai MJ, O'Malley BW. Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1. Mol Cell. 2008 Feb 29; 29(4):465-76. PMID: 18313384.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    69. Franco HL, Jeong JW, Tsai SY, Lydon JP, DeMayo FJ. In vivo analysis of progesterone receptor action in the uterus during embryo implantation. Semin Cell Dev Biol. 2008 Apr; 19(2):178-86. PMID: 18280760.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    70. Faedo A, Tomassy GS, Ruan Y, Teichmann H, Krauss S, Pleasure SJ, Tsai SY, Tsai MJ, Studer M, Rubenstein JL. COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling. Cereb Cortex. 2008 Sep; 18(9):2117-31. PMID: 18165280.
      Citations: 67     Fields:    Translation:AnimalsCells
    71. Srinivasan RS, Dillard ME, Lagutin OV, Lin FJ, Tsai S, Tsai MJ, Samokhvalov IM, Oliver G. Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev. 2007 Oct 01; 21(19):2422-32. PMID: 17908929.
      Citations: 239     Fields:    Translation:AnimalsCells
    72. Lin FJ, Tsai MJ, Tsai SY. Artery and vein formation: a tug of war between different forces. EMBO Rep. 2007 Oct; 8(10):920-4. PMID: 17906673.
      Citations: 24     Fields:    Translation:HumansAnimals
    73. Lee KY, Jeong JW, Tsai SY, Lydon JP, DeMayo FJ. Mouse models of implantation. Trends Endocrinol Metab. 2007 Aug; 18(6):234-9. PMID: 17588769.
      Citations: 32     Fields:    Translation:Animals
    74. Kurihara I, Lee DK, Petit FG, Jeong J, Lee K, Lydon JP, DeMayo FJ, Tsai MJ, Tsai SY. COUP-TFII mediates progesterone regulation of uterine implantation by controlling ER activity. PLoS Genet. 2007 Jun; 3(6):e102. PMID: 17590085.
      Citations: 105     Fields:    Translation:AnimalsCells
    75. Lee KY, Jeong JW, Wang J, Ma L, Martin JF, Tsai SY, Lydon JP, DeMayo FJ. Bmp2 is critical for the murine uterine decidual response. Mol Cell Biol. 2007 Aug; 27(15):5468-78. PMID: 17515606.
      Citations: 151     Fields:    Translation:HumansAnimalsCells
    76. Petit FG, Jamin SP, Kurihara I, Behringer RR, DeMayo FJ, Tsai MJ, Tsai SY. Deletion of the orphan nuclear receptor COUP-TFII in uterus leads to placental deficiency. Proc Natl Acad Sci U S A. 2007 Apr 10; 104(15):6293-8. PMID: 17404209.
      Citations: 46     Fields:    Translation:AnimalsCells
    77. Qin J, Suh JM, Kim BJ, Yu CT, Tanaka T, Kodama T, Tsai MJ, Tsai SY. The expression pattern of nuclear receptors during cerebellar development. Dev Dyn. 2007 Mar; 236(3):810-20. PMID: 17205580.
      Citations: 15     Fields:    Translation:Animals
    78. Han SJ, Tsai SY, Tsai MJ, O'Malley BW. Distinct temporal and spatial activities of RU486 on progesterone receptor function in reproductive organs of ovariectomized mice. Endocrinology. 2007 May; 148(5):2471-86. PMID: 17303655.
      Citations: 12     Fields:    Translation:AnimalsCells
    79. Ray D, Terao Y, Fuhrken PG, Ma ZQ, DeMayo FJ, Christov K, Heerema NA, Franks R, Tsai SY, Papoutsakis ET, Kiyokawa H. Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability. Cancer Res. 2007 Feb 01; 67(3):984-91. PMID: 17283130.
      Citations: 30     Fields:    Translation:HumansAnimals
    80. Li C, Wu RC, Amazit L, Tsai SY, Tsai MJ, O'Malley BW. Specific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasome-dependent turnover. Mol Cell Biol. 2007 Feb; 27(4):1296-308. PMID: 17158932.
      Citations: 28     Fields:    Translation:HumansCells
    81. Yan J, Yu CT, Ozen M, Ittmann M, Tsai SY, Tsai MJ. Steroid receptor coactivator-3 and activator protein-1 coordinately regulate the transcription of components of the insulin-like growth factor/AKT signaling pathway. Cancer Res. 2006 Nov 15; 66(22):11039-46. PMID: 17108143.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    82. Louet JF, Coste A, Amazit L, Tannour-Louet M, Wu RC, Tsai SY, Tsai MJ, Auwerx J, O'Malley BW. Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program. Proc Natl Acad Sci U S A. 2006 Nov 21; 103(47):17868-73. PMID: 17098861.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    83. Suh JM, Yu CT, Tang K, Tanaka T, Kodama T, Tsai MJ, Tsai SY. The expression profiles of nuclear receptors in the developing and adult kidney. Mol Endocrinol. 2006 Dec; 20(12):3412-20. PMID: 16973757.
      Citations: 18     Fields:    Translation:Animals
    84. Lee K, Jeong J, Kwak I, Yu CT, Lanske B, Soegiarto DW, Toftgard R, Tsai MJ, Tsai S, Lydon JP, DeMayo FJ. Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus. Nat Genet. 2006 Oct; 38(10):1204-9. PMID: 16951680.
      Citations: 128     Fields:    Translation:AnimalsCells
    85. Yan J, Tsai SY, Tsai MJ. SRC-3/AIB1: transcriptional coactivator in oncogenesis. Acta Pharmacol Sin. 2006 Apr; 27(4):387-94. PMID: 16539836.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    86. Li X, Lonard DM, Jung SY, Malovannaya A, Feng Q, Qin J, Tsai SY, Tsai MJ, O'Malley BW. The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell. 2006 Jan 27; 124(2):381-92. PMID: 16439211.
      Citations: 123     Fields:    Translation:HumansAnimalsCells
    87. Yi P, Wu RC, Sandquist J, Wong J, Tsai SY, Tsai MJ, Means AR, O'Malley BW. Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1). Mol Cell Biol. 2005 Nov; 25(21):9687-99. PMID: 16227615.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    88. You LR, Takamoto N, Yu CT, Tanaka T, Kodama T, Demayo FJ, Tsai SY, Tsai MJ. Mouse lacking COUP-TFII as an animal model of Bochdalek-type congenital diaphragmatic hernia. Proc Natl Acad Sci U S A. 2005 Nov 08; 102(45):16351-6. PMID: 16251273.
      Citations: 71     Fields:    Translation:Animals
    89. Schillinger KJ, Tsai SY, Taffet GE, Reddy AK, Marian AJ, Entman ML, Oka K, Chan L, O'Malley BW. Regulatable atrial natriuretic peptide gene therapy for hypertension. Proc Natl Acad Sci U S A. 2005 Sep 27; 102(39):13789-94. PMID: 16162668.
      Citations: 22     Fields:    Translation:AnimalsCells
    90. Han SJ, Jeong J, Demayo FJ, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Dynamic cell type specificity of SRC-1 coactivator in modulating uterine progesterone receptor function in mice. Mol Cell Biol. 2005 Sep; 25(18):8150-65. PMID: 16135805.
      Citations: 18     Fields:    Translation:AnimalsCells
    91. Han SJ, DeMayo FJ, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor. Mol Endocrinol. 2006 Jan; 20(1):45-55. PMID: 16141356.
      Citations: 43     Fields:    Translation:AnimalsCells
    92. Zhou HJ, Yan J, Luo W, Ayala G, Lin SH, Erdem H, Ittmann M, Tsai SY, Tsai MJ. SRC-3 is required for prostate cancer cell proliferation and survival. Cancer Res. 2005 Sep 01; 65(17):7976-83. PMID: 16140970.
      Citations: 112     Fields:    Translation:HumansAnimalsCells
    93. Ye X, Han SJ, Tsai SY, DeMayo FJ, Xu J, Tsai MJ, O'Malley BW. Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice. Proc Natl Acad Sci U S A. 2005 Jul 05; 102(27):9487-92. PMID: 15983373.
      Citations: 20     Fields:    Translation:Animals
    94. Takamoto N, Kurihara I, Lee K, Demayo FJ, Tsai MJ, Tsai SY. Haploinsufficiency of chicken ovalbumin upstream promoter transcription factor II in female reproduction. Mol Endocrinol. 2005 Sep; 19(9):2299-308. PMID: 15890675.
      Citations: 41     Fields:    Translation:Animals
    95. You LR, Lin FJ, Lee CT, DeMayo FJ, Tsai MJ, Tsai SY. Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature. 2005 May 05; 435(7038):98-104. PMID: 15875024.
      Citations: 249     Fields:    Translation:AnimalsCells
    96. Takamoto N, You LR, Moses K, Chiang C, Zimmer WE, Schwartz RJ, DeMayo FJ, Tsai MJ, Tsai SY. COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development. 2005 May; 132(9):2179-89. PMID: 15829524.
      Citations: 70     Fields:    Translation:Animals
    97. Tsai MJ, You LR, Tsai SY. Surprise in the Battle Field of Vein vs. Artery. Organogenesis. 2005 Apr; 2(2):31-2. PMID: 19521563.
      Citations:    Fields:    
    98. Lee CT, Li L, Takamoto N, Martin JF, Demayo FJ, Tsai MJ, Tsai SY. The nuclear orphan receptor COUP-TFII is required for limb and skeletal muscle development. Mol Cell Biol. 2004 Dec; 24(24):10835-43. PMID: 15572686.
      Citations: 45     Fields:    Translation:AnimalsCells
    99. Petit FG, Salas R, Tsai MJ, Tsai SY. The regulation of COUP-TFII gene expression by Ets-1 is enhanced by the steroid receptor co-activators. Mech Ageing Dev. 2004 Oct-Nov; 125(10-11):719-32. PMID: 15541767.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    100. Wu RC, Qin J, Yi P, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol Cell. 2004 Sep 24; 15(6):937-49. PMID: 15383283.
      Citations: 132     Fields:    Translation:HumansAnimalsCells
    101. Yamaguchi H, Zhou C, Lin SC, Durand B, Tsai SY, Tsai MJ. The nuclear orphan receptor COUP-TFI is important for differentiation of oligodendrocytes. Dev Biol. 2004 Feb 15; 266(2):238-51. PMID: 14738874.
      Citations: 25     Fields:    Translation:AnimalsCells
    102. Kwak I, Tsai SY, DeMayo FJ. Genetically engineered mouse models for lung cancer. Annu Rev Physiol. 2004; 66:647-63. PMID: 14977417.
      Citations: 8     Fields:    Translation:Animals
    103. Chua SS, Ma Z, Ngan E, Tsai SY. Cdc25B as a steroid receptor coactivator. Vitam Horm. 2004; 68:231-56. PMID: 15193457.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    104. Lonard DM, Tsai SY, O'Malley BW. Selective estrogen receptor modulators 4-hydroxytamoxifen and raloxifene impact the stability and function of SRC-1 and SRC-3 coactivator proteins. Mol Cell Biol. 2004 Jan; 24(1):14-24. PMID: 14673139.
      Citations: 28     Fields:    Translation:HumansCells
    105. Zhou G, Hashimoto Y, Kwak I, Tsai SY, Tsai MJ. Role of the steroid receptor coactivator SRC-3 in cell growth. Mol Cell Biol. 2003 Nov; 23(21):7742-55. PMID: 14560019.
      Citations: 57     Fields:    Translation:AnimalsCells
    106. Zhou HJ, Tsai SY, Tsai MJ. RNAi technology and its use in studying the function of nuclear receptors and coregulators. Nucl Recept Signal. 2003; 1:e008. PMID: 16604180.
      Citations: 2     Fields:    
    107. Park JI, Tsai SY, Tsai MJ. Molecular mechanism of chicken ovalbumin upstream promoter-transcription factor (COUP-TF) actions. Keio J Med. 2003 Sep; 52(3):174-81. PMID: 14529150.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    108. Nemoz-Gaillard E, Tsai MJ, Tsai SY. Expression and function profiling of orphan nuclear receptors using bacterial artificial chromosome (BAC) transgenesis. Nucl Recept Signal. 2003; 1:e005. PMID: 16604177.
      Citations:    Fields:    
    109. Li X, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol. 2003 Jun; 23(11):3763-73. PMID: 12748280.
      Citations: 79     Fields:    Translation:HumansAnimalsCells
    110. Ngan ES, Hashimoto Y, Ma ZQ, Tsai MJ, Tsai SY. Overexpression of Cdc25B, an androgen receptor coactivator, in prostate cancer. Oncogene. 2003 Feb 06; 22(5):734-9. PMID: 12569365.
      Citations: 30     Fields:    Translation:HumansCells
    111. Takamoto N, Zhao B, Tsai SY, DeMayo FJ. Identification of Indian hedgehog as a progesterone-responsive gene in the murine uterus. Mol Endocrinol. 2002 Oct; 16(10):2338-48. PMID: 12351698.
      Citations: 67     Fields:    Translation:AnimalsCells
    112. Navab R, Wang Y, Chow YH, Wang A, Jankov RP, Takamoto N, Tsai SY, Tsai MJ, Tanswell AK, Hu J. Regulation of human Clara cell 10 kD protein expression by chicken ovalbumin upstream promoter transcription factors (COUP-TFs). Am J Respir Cell Mol Biol. 2002 Sep; 27(3):273-85. PMID: 12204889.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    113. Ngan ES, Ma ZQ, Chua SS, DeMayo FJ, Tsai SY. Inducible expression of FGF-3 in mouse mammary gland. Proc Natl Acad Sci U S A. 2002 Aug 20; 99(17):11187-92. PMID: 12169667.
      Citations: 7     Fields:    Translation:AnimalsCells
    114. Cao T, Tsai SY, O'Malley BW, Wang XJ, Roop DR. The epidermis as a bioreactor: topically regulated cutaneous delivery into the circulation. Hum Gene Ther. 2002 Jun 10; 13(9):1075-80. PMID: 12067440.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    115. Liu Z, Auboeuf D, Wong J, Chen JD, Tsai SY, Tsai MJ, O'Malley BW. Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):7940-4. PMID: 12048256.
      Citations: 36     Fields:    Translation:HumansCells
    116. Wu RC, Qin J, Hashimoto Y, Wong J, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol. 2002 May; 22(10):3549-61. PMID: 11971985.
      Citations: 111     Fields:    Translation:HumansAnimalsCells
    117. Ngan ES, Schillinger K, DeMayo F, Tsai SY. The mifepristone-inducible gene regulatory system in mouse models of disease and gene therapy. Semin Cell Dev Biol. 2002 Apr; 13(2):143-9. PMID: 12240599.
      Citations: 11     Fields:    Translation:Animals
    118. Chua SS, Ma ZQ, Gong L, Lin SH, DeMayo FJ, Tsai SY. Ectopic expression of FGF-3 results in abnormal prostate and Wolffian duct development. Oncogene. 2002 Mar 14; 21(12):1899-908. PMID: 11896623.
      Citations: 6     Fields:    Translation:Animals
    119. DeMayo FJ, Zhao B, Takamoto N, Tsai SY. Mechanisms of action of estrogen and progesterone. Ann N Y Acad Sci. 2002 Mar; 955:48-59; discussion 86-8, 396-406. PMID: 11949965.
      Citations: 25     Fields:    Translation:Animals
    120. Ye X, Schillinger K, Burcin MM, Tsai SY, O'Malley BW. Ligand-inducible transgene regulation for gene therapy. Methods Enzymol. 2002; 346:551-61. PMID: 11883090.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    121. Salas R, Petit FG, Pipaon C, Tsai MJ, Tsai SY. Induction of chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI ) gene expression is mediated by ETS factor binding sites. Eur J Biochem. 2002 Jan; 269(1):317-25. PMID: 11784326.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    122. Ma ZQ, Liu Z, Ngan ES, Tsai SY. Cdc25B functions as a novel coactivator for the steroid receptors. Mol Cell Biol. 2001 Dec; 21(23):8056-67. PMID: 11689696.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    123. Liu Z, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Sequential recruitment of steroid receptor coactivator-1 (SRC-1) and p300 enhances progesterone receptor-dependent initiation and reinitiation of transcription from chromatin. Proc Natl Acad Sci U S A. 2001 Oct 23; 98(22):12426-31. PMID: 11606780.
      Citations: 41     Fields:    Translation:HumansCells
    124. DeMayo FJ, Tsai SY. Targeted gene regulation and gene ablation. Trends Endocrinol Metab. 2001 Oct; 12(8):348-53. PMID: 11551808.
      Citations: 5     Fields:    Translation:HumansAnimals
    125. Zhou C, Tsai SY, Tsai MJ. COUP-TFI: an intrinsic factor for early regionalization of the neocortex. Genes Dev. 2001 Aug 15; 15(16):2054-9. PMID: 11511537.
      Citations: 58     Fields:    Translation:Animals
    126. Cooney AJ, Lee CT, Lin SC, Tsai SY, Tsai MJ. Physiological function of the orphans GCNF and COUP-TF. Trends Endocrinol Metab. 2001 Aug; 12(6):247-51. PMID: 11445441.
      Citations: 9     Fields:    Translation:HumansAnimals
    127. Zhao B, Chua SS, Burcin MM, Reynolds SD, Stripp BR, Edwards RA, Finegold MJ, Tsai SY, DeMayo FJ. Phenotypic consequences of lung-specific inducible expression of FGF-3. Proc Natl Acad Sci U S A. 2001 May 08; 98(10):5898-903. PMID: 11331772.
      Citations: 9     Fields:    Translation:Animals
    128. Elberg G, Gimble JM, Tsai SY. Modulation of the murine peroxisome proliferator-activated receptor gamma 2 promoter activity by CCAAT/enhancer-binding proteins. J Biol Chem. 2000 Sep 08; 275(36):27815-22. PMID: 10862621.
      Citations: 25     Fields:    Translation:AnimalsCells
    129. Pereira FA, Tsai MJ, Tsai SY. COUP-TF orphan nuclear receptors in development and differentiation. Cell Mol Life Sci. 2000 Sep; 57(10):1388-98. PMID: 11078018.
      Citations: 69     Fields:    Translation:HumansAnimals
    130. Pierson TM, Wang Y, DeMayo FJ, Matzuk MM, Tsai SY, Omalley BW. Regulable expression of inhibin A in wild-type and inhibin alpha null mice. Mol Endocrinol. 2000 Jul; 14(7):1075-85. PMID: 10894156.
      Citations: 23     Fields:    Translation:AnimalsCells
    131. Zhou C, Tsai SY, Tsai M. From apoptosis to angiogenesis: new insights into the roles of nuclear orphan receptors, chicken ovalbumin upstream promoter-transcription factors, during development. Biochim Biophys Acta. 2000 Mar 27; 1470(2):M63-8. PMID: 10722928.
      Citations: 4     Fields:    Translation:Animals
    132. Wang Y, Tsai SY, O'Malley BW. An antiprogestin regulable gene switch for induction of gene expression in vivo. Adv Pharmacol. 2000; 47:343-55. PMID: 10582091.
      Citations: 1     Fields:    Translation:HumansAnimals
    133. Zhou C, Qiu Y, Pereira FA, Crair MC, Tsai SY, Tsai MJ. The nuclear orphan receptor COUP-TFI is required for differentiation of subplate neurons and guidance of thalamocortical axons. Neuron. 1999 Dec; 24(4):847-59. PMID: 10624948.
      Citations: 66     Fields:    Translation:AnimalsCells
    134. Lu S, Tsai SY, Tsai MJ. Molecular mechanisms of androgen-independent growth of human prostate cancer LNCaP-AI cells. Endocrinology. 1999 Nov; 140(11):5054-9. PMID: 10537131.
      Citations: 31     Fields:    Translation:HumansCells
    135. Liu Z, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator-1 (SRC-1) enhances ligand-dependent and receptor-dependent cell-free transcription of chromatin. Proc Natl Acad Sci U S A. 1999 Aug 17; 96(17):9485-90. PMID: 10449719.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    136. Ma ZQ, Chua SS, DeMayo FJ, Tsai SY. Induction of mammary gland hyperplasia in transgenic mice over-expressing human Cdc25B. Oncogene. 1999 Aug 12; 18(32):4564-76. PMID: 10467401.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    137. Pereira FA, Qiu Y, Zhou G, Tsai MJ, Tsai SY. The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development. Genes Dev. 1999 Apr 15; 13(8):1037-49. PMID: 10215630.
      Citations: 171     Fields:    Translation:Animals
    138. Lanz RB, McKenna NJ, Onate SA, Albrecht U, Wong J, Tsai SY, Tsai MJ, O'Malley BW. A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell. 1999 Apr 02; 97(1):17-27. PMID: 10199399.
      Citations: 280     Fields:    Translation:HumansAnimalsCells
    139. McKenna NJ, Xu J, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions. J Steroid Biochem Mol Biol. 1999 Apr-Jun; 69(1-6):3-12. PMID: 10418975.
      Citations: 83     Fields:    Translation:HumansAnimals
    140. Pipaón C, Tsai SY, Tsai MJ. COUP-TF upregulates NGFI-A gene expression through an Sp1 binding site. Mol Cell Biol. 1999 Apr; 19(4):2734-45. PMID: 10082539.
      Citations: 38     Fields:    Translation:AnimalsCells
    141. Ma ZQ, Tsai MJ, Tsai SY. Suppression of gene expression by tethering KRAB domain to promoter of ER target genes. J Steroid Biochem Mol Biol. 1999 Apr-Jun; 69(1-6):155-63. PMID: 10418989.
      Citations: 3     Fields:    Translation:HumansCells
    142. Lu S, Liu M, Epner DE, Tsai SY, Tsai MJ. Androgen regulation of the cyclin-dependent kinase inhibitor p21 gene through an androgen response element in the proximal promoter. Mol Endocrinol. 1999 Mar; 13(3):376-84. PMID: 10076995.
      Citations: 57     Fields:    Translation:HumansCells
    143. Nawaz Z, Lonard DM, Smith CL, Lev-Lehman E, Tsai SY, Tsai MJ, O'Malley BW. The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily. Mol Cell Biol. 1999 Feb; 19(2):1182-9. PMID: 9891052.
      Citations: 144     Fields:    Translation:HumansCells
    144. Burcin MM, Schiedner G, Kochanek S, Tsai SY, O'Malley BW. Adenovirus-mediated regulable target gene expression in vivo. Proc Natl Acad Sci U S A. 1999 Jan 19; 96(2):355-60. PMID: 9892637.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    145. McKenna NJ, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. Distinct steady-state nuclear receptor coregulator complexes exist in vivo. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11697-702. PMID: 9751728.
      Citations: 50     Fields:    Translation:HumansCells
    146. Onate SA, Boonyaratanakornkit V, Spencer TE, Tsai SY, Tsai MJ, Edwards DP, O'Malley BW. The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors. J Biol Chem. 1998 May 15; 273(20):12101-8. PMID: 9575154.
      Citations: 102     Fields:    Translation:HumansCells
    147. Xu J, Qiu Y, DeMayo FJ, Tsai SY, Tsai MJ, O'Malley BW. Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. Science. 1998 Mar 20; 279(5358):1922-5. PMID: 9506940.
      Citations: 195     Fields:    Translation:AnimalsCells
    148. Tsai SY, O'Malley BW, DeMayo FJ, Wang Y, Chua SS. A novel RU486 inducible system for the activation and repression of genes. Adv Drug Deliv Rev. 1998 Mar 02; 30(1-3):23-31. PMID: 10837599.
      Citations: 8     Fields:    
    149. Burcin MM, O'Malley BW, Tsai SY. A regulatory system for target gene expression. Front Biosci. 1998 Jan 01; 3:c1-7. PMID: 9478886.
      Citations: 16     Fields:    Translation:HumansAnimals
    150. Krishnan V, Pereira FA, Qiu Y, Chen CH, Beachy PA, Tsai SY, Tsai MJ. Mediation of Sonic hedgehog-induced expression of COUP-TFII by a protein phosphatase. Science. 1997 Dec 12; 278(5345):1947-50. PMID: 9395397.
      Citations: 44     Fields:    Translation:AnimalsCells
    151. Lu S, Tsai SY, Tsai MJ. Regulation of androgen-dependent prostatic cancer cell growth: androgen regulation of CDK2, CDK4, and CKI p16 genes. Cancer Res. 1997 Oct 15; 57(20):4511-6. PMID: 9377562.
      Citations: 35     Fields:    Translation:HumansCells
    152. Spencer TE, Jenster G, Burcin MM, Allis CD, Zhou J, Mizzen CA, McKenna NJ, Onate SA, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator-1 is a histone acetyltransferase. Nature. 1997 Sep 11; 389(6647):194-8. PMID: 9296499.
      Citations: 313     Fields:    Translation:HumansAnimalsCells
    153. Krishnan V, Elberg G, Tsai MJ, Tsai SY. Identification of a novel sonic hedgehog response element in the chicken ovalbumin upstream promoter-transcription factor II promoter. Mol Endocrinol. 1997 Sep; 11(10):1458-66. PMID: 9280061.
      Citations: 19     Fields:    Translation:AnimalsCells
    154. Qiu Y, Pereira FA, DeMayo FJ, Lydon JP, Tsai SY, Tsai MJ. Null mutation of mCOUP-TFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization. Genes Dev. 1997 Aug 01; 11(15):1925-37. PMID: 9271116.
      Citations: 80     Fields:    Translation:AnimalsCells
    155. Jenster G, Spencer TE, Burcin MM, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor induction of gene transcription: a two-step model. Proc Natl Acad Sci U S A. 1997 Jul 22; 94(15):7879-84. PMID: 9223281.
      Citations: 52     Fields:    Translation:HumansCells
    156. Shibata H, Nawaz Z, Tsai SY, O'Malley BW, Tsai MJ. Gene silencing by chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is mediated by transcriptional corepressors, nuclear receptor-corepressor (N-CoR) and silencing mediator for retinoic acid receptor and thyroid hormone receptor (SMRT). Mol Endocrinol. 1997 Jun; 11(6):714-24. PMID: 9171235.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    157. Wang Y, Xu J, Pierson T, O'Malley BW, Tsai SY. Positive and negative regulation of gene expression in eukaryotic cells with an inducible transcriptional regulator. Gene Ther. 1997 May; 4(5):432-41. PMID: 9274720.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    158. Tsai SY, Tsai MJ. Chick ovalbumin upstream promoter-transcription factors (COUP-TFs): coming of age. Endocr Rev. 1997 Apr; 18(2):229-40. PMID: 9101138.
      Citations: 122     Fields:    Translation:HumansAnimalsCells
    159. Wang Y, DeMayo FJ, Tsai SY, O'Malley BW. Ligand-inducible and liver-specific target gene expression in transgenic mice. Nat Biotechnol. 1997 Mar; 15(3):239-43. PMID: 9062922.
      Citations: 49     Fields:    Translation:AnimalsCells
    160. Wang Y, O'Malley BW, Tsai SY. Inducible system designed for future gene therapy. Methods Mol Biol. 1997; 63:401-13. PMID: 9113665.
      Citations: 1     Fields:    Translation:AnimalsCells
    161. Shibata H, Spencer TE, Oñate SA, Jenster G, Tsai SY, Tsai MJ, O'Malley BW. Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action. Recent Prog Horm Res. 1997; 52:141-64; discussion 164-5. PMID: 9238851.
      Citations: 99     Fields:    Translation:HumansAnimalsCells
    162. Xu J, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. The extreme C terminus of progesterone receptor contains a transcriptional repressor domain that functions through a putative corepressor. Proc Natl Acad Sci U S A. 1996 Oct 29; 93(22):12195-9. PMID: 8901556.
      Citations: 17     Fields:    Translation:HumansCells
    163. Leng X, Cooney AJ, Tsai SY, Tsai MJ. Molecular mechanisms of COUP-TF-mediated transcriptional repression: evidence for transrepression and active repression. Mol Cell Biol. 1996 May; 16(5):2332-40. PMID: 8628300.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    164. Qiu Y, Krishnan V, Pereira FA, Tsai SY, Tsai MJ. Chicken ovalbumin upstream promoter-transcription factors and their regulation. J Steroid Biochem Mol Biol. 1996 Jan; 56(1-6 Spec No):81-5. PMID: 8603050.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    165. Oñate SA, Tsai SY, Tsai MJ, O'Malley BW. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science. 1995 Nov 24; 270(5240):1354-7. PMID: 7481822.
      Citations: 545     Fields:    Translation:HumansCells
    166. Shen WJ, Kim HS, Tsai SY. Stimulation of human insulin receptor gene expression by retinoblastoma gene product. J Biol Chem. 1995 Sep 01; 270(35):20525-9. PMID: 7657628.
      Citations: 4     Fields:    Translation:HumansCells
    167. Qiu Y, Krishnan V, Zeng Z, Gilbert DJ, Copeland NG, Gibson L, Yang-Feng T, Jenkins NA, Tsai MJ, Tsai SY. Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes. Genomics. 1995 Sep 01; 29(1):240-6. PMID: 8530078.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    168. Pereira FA, Qiu Y, Tsai MJ, Tsai SY. Chicken ovalbumin upstream promoter transcription factor (COUP-TF): expression during mouse embryogenesis. J Steroid Biochem Mol Biol. 1995 Jun; 53(1-6):503-8. PMID: 7626501.
      Citations: 33     Fields:    Translation:Animals
    169. Kim HS, Lee JK, Tsai SY. E1a activation of insulin receptor gene expression is mediated by Sp1-binding sites. Mol Endocrinol. 1995 Feb; 9(2):178-86. PMID: 7776968.
      Citations:    Fields:    Translation:HumansCells
    170. Baniahmad A, Leng X, Burris TP, Tsai SY, Tsai MJ, O'Malley BW. The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing. Mol Cell Biol. 1995 Jan; 15(1):76-86. PMID: 7799971.
      Citations: 74     Fields:    Translation:HumansCells
    171. Leng X, Blanco J, Tsai SY, Ozato K, O'Malley BW, Tsai MJ. Mouse retinoid X receptor contains a separable ligand-binding and transactivation domain in its E region. Mol Cell Biol. 1995 Jan; 15(1):255-63. PMID: 7799932.
      Citations: 25     Fields:    Translation:AnimalsCells
    172. Leng X, Blanco J, Tsai SY, Ozato K, O'Malley BW, Tsai MJ. Mechanisms for synergistic activation of thyroid hormone receptor and retinoid X receptor on different response elements. J Biol Chem. 1994 Dec 16; 269(50):31436-42. PMID: 7989311.
      Citations: 13     Fields:    Translation:Cells
    173. Beekman JM, Cooney AJ, Elliston JF, Tsai SY, Tsai MJ. A rapid one-step method to purify baculovirus-expressed human estrogen receptor to be used in the analysis of the oxytocin promoter. Gene. 1994 Sep 02; 146(2):285-9. PMID: 8076833.
      Citations: 1     Fields:    Translation:HumansCells
    174. Wang Y, O'Malley BW, Tsai SY, O'Malley BW. A regulatory system for use in gene transfer. Proc Natl Acad Sci U S A. 1994 Aug 16; 91(17):8180-4. PMID: 8058776.
      Citations: 86     Fields:    Translation:HumansAnimalsCells
    175. Qiu Y, Tsai SY, Tsai MJ. COUP-TF an orphan member of the steroid/thyroid hormone receptor superfamily. Trends Endocrinol Metab. 1994 Aug; 5(6):234-9. PMID: 18407213.
      Citations: 15     Fields:    
    176. Zeng Z, Allan GF, Thaller C, Cooney AJ, Tsai SY, O'Malley BW, Tsai MJ. Detection of potential ligands for nuclear receptors in cellular extracts. Endocrinology. 1994 Jul; 135(1):248-52. PMID: 8013359.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    177. Qiu Y, Cooney AJ, Kuratani S, DeMayo FJ, Tsai SY, Tsai MJ. Spatiotemporal expression patterns of chicken ovalbumin upstream promoter-transcription factors in the developing mouse central nervous system: evidence for a role in segmental patterning of the diencephalon. Proc Natl Acad Sci U S A. 1994 May 10; 91(10):4451-5. PMID: 8183930.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    178. Lee JK, Tsai SY. Multiple hormone response elements can confer glucocorticoid regulation on the human insulin receptor gene. Mol Endocrinol. 1994 May; 8(5):625-34. PMID: 8058070.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    179. Wang Y, Hahn TM, Tsai SY, Woo SL. Functional characterization of a unique liver gene promoter. J Biol Chem. 1994 Mar 25; 269(12):9137-46. PMID: 8132651.
      Citations: 5     Fields:    Translation:HumansCells
    180. Lu B, Rothnagel JA, Longley MA, Tsai SY, Roop DR. Differentiation-specific expression of human keratin 1 is mediated by a composite AP-1/steroid hormone element. J Biol Chem. 1994 Mar 11; 269(10):7443-9. PMID: 7510286.
      Citations: 13     Fields:    Translation:HumansCells
    181. Lutz B, Kuratani S, Cooney AJ, Wawersik S, Tsai SY, Eichele G, Tsai MJ. Developmental regulation of the orphan receptor COUP-TF II gene in spinal motor neurons. Development. 1994 Jan; 120(1):25-36. PMID: 8119130.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    182. Leng X, Tsai SY, O'Malley BW, Tsai MJ. Ligand-dependent conformational changes in thyroid hormone and retinoic acid receptors are potentially enhanced by heterodimerization with retinoic X receptor. J Steroid Biochem Mol Biol. 1993 Dec; 46(6):643-61. PMID: 8274399.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    183. Beekman JM, Allan GF, Tsai SY, Tsai MJ, O'Malley BW. Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain. Mol Endocrinol. 1993 Oct; 7(10):1266-74. PMID: 8264659.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    184. Cooney AJ, Leng X, Tsai SY, O'Malley BW, Tsai MJ. Multiple mechanisms of chicken ovalbumin upstream promoter transcription factor-dependent repression of transactivation by the vitamin D, thyroid hormone, and retinoic acid receptors. J Biol Chem. 1993 Feb 25; 268(6):4152-60. PMID: 8382695.
      Citations: 60     Fields:    Translation:AnimalsCells
    185. Allan GF, Tsai SY, Tsai MJ, O'Malley BW. Ligand-dependent conformational changes in the progesterone receptor are necessary for events that follow DNA binding. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):11750-4. PMID: 1465392.
      Citations: 21     Fields:    Translation:HumansCells
    186. Baniahmad A, Tsai SY, O'Malley BW, Tsai MJ. Kindred S thyroid hormone receptor is an active and constitutive silencer and a repressor for thyroid hormone and retinoic acid responses. Proc Natl Acad Sci U S A. 1992 Nov 15; 89(22):10633-7. PMID: 1359543.
      Citations: 31     Fields:    Translation:HumansCells
    187. Allan GF, Leng X, Tsai SY, Weigel NL, Edwards DP, Tsai MJ, O'Malley BW. Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation. J Biol Chem. 1992 Sep 25; 267(27):19513-20. PMID: 1326555.
      Citations: 63     Fields:    Translation:HumansCells
    188. Ing NH, Beekman JM, Tsai SY, Tsai MJ, O'Malley BW. Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II). J Biol Chem. 1992 Sep 05; 267(25):17617-23. PMID: 1517211.
      Citations: 100     Fields:    Translation:HumansCells
    189. Cooney AJ, Tsai SY, O'Malley BW, Tsai MJ. Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptors. Mol Cell Biol. 1992 Sep; 12(9):4153-63. PMID: 1324415.
      Citations: 123     Fields:    Translation:AnimalsCells
    190. Bagchi MK, Tsai MJ, O'Malley BW, Tsai SY. Analysis of the mechanism of steroid hormone receptor-dependent gene activation in cell-free systems. Endocr Rev. 1992 Aug; 13(3):525-35. PMID: 1425487.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    191. Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Ligand and DNA-dependent phosphorylation of human progesterone receptor in vitro. Proc Natl Acad Sci U S A. 1992 Apr 01; 89(7):2664-8. PMID: 1557371.
      Citations: 15     Fields:    Translation:HumansCells
    192. Elliston JF, Beekman JM, Tsai SY, O'Malley BW, Tsai MJ. Hormone activation of baculovirus expressed progesterone receptors. J Biol Chem. 1992 Mar 15; 267(8):5193-8. PMID: 1544902.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    193. Lee JK, Tam JW, Tsai MJ, Tsai SY. Identification of cis- and trans-acting factors regulating the expression of the human insulin receptor gene. J Biol Chem. 1992 Mar 05; 267(7):4638-45. PMID: 1311316.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    194. Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Progesterone enhances target gene transcription by receptor free of heat shock proteins hsp90, hsp56, and hsp70. Mol Cell Biol. 1991 Oct; 11(10):4998-5004. PMID: 1922029.
      Citations: 14     Fields:    Translation:HumansCells
    195. Bradshaw MS, Tsai SY, Leng XH, Dobson AD, Conneely OM, O'Malley BW, Tsai MJ. Studies on the mechanism of functional cooperativity between progesterone and estrogen receptors. J Biol Chem. 1991 Sep 05; 266(25):16684-90. PMID: 1885597.
      Citations: 8     Fields:    Translation:Cells
    196. Cooney AJ, Tsai SY, O'Malley BW, Tsai MJ. Chicken ovalbumin upstream promoter transcription factor binds to a negative regulatory region in the human immunodeficiency virus type 1 long terminal repeat. J Virol. 1991 Jun; 65(6):2853-60. PMID: 2033658.
      Citations: 33     Fields:    Translation:HumansCells
    197. Allan GF, Ing NH, Tsai SY, Srinivasan G, Weigel NL, Thompson EB, Tsai MJ, O'Malley BW. Synergism between steroid response and promoter elements during cell-free transcription. J Biol Chem. 1991 Mar 25; 266(9):5905-10. PMID: 2005127.
      Citations: 10     Fields:    Translation:AnimalsCells
    198. Allan GF, Tsai SY, O'Malley BW, Tsai MJ. Steroid hormone receptors and in vitro transcription. Bioessays. 1991 Feb; 13(2):73-8. PMID: 2029268.
      Citations: 1     Fields:    Translation:AnimalsCells
    199. Wang LH, Ing NH, Tsai SY, O'Malley BW, Tsai MJ. The COUP-TFs compose a family of functionally related transcription factors. Gene Expr. 1991; 1(3):207-16. PMID: 1820218.
      Citations: 43     Fields:    Translation:HumansCells
    200. O'Malley BW, Tsai SY, Bagchi M, Weigel NL, Schrader WT, Tsai MJ. Molecular mechanism of action of a steroid hormone receptor. Recent Prog Horm Res. 1991; 47:1-24; discussion 24-6. PMID: 1745818.
      Citations: 7     Fields:    Translation:AnimalsCells
    201. Elliston JF, Fawell SE, Klein-Hitpass L, Tsai SY, Tsai MJ, Parker MG, O'Malley BW. Mechanism of estrogen receptor-dependent transcription in a cell-free system. Mol Cell Biol. 1990 Dec; 10(12):6607-12. PMID: 2247075.
      Citations: 16     Fields:    Translation:AnimalsCells
    202. Tsai SY, Srinivasan G, Allan GF, Thompson EB, O'Malley BW, Tsai MJ. Recombinant human glucocorticoid receptor induces transcription of hormone response genes in vitro. J Biol Chem. 1990 Oct 05; 265(28):17055-61. PMID: 2170364.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    203. Elliston JF, Tsai SY, O'Malley BW, Tsai MJ. Superactive estrogen receptors. Potent activators of gene expression. J Biol Chem. 1990 Jul 15; 265(20):11517-21. PMID: 2164005.
      Citations: 6     Fields:    Translation:AnimalsCells
    204. Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Identification of a functional intermediate in receptor activation in progesterone-dependent cell-free transcription. Nature. 1990 Jun 07; 345(6275):547-50. PMID: 2348863.
      Citations: 28     Fields:    Translation:HumansCells
    205. Bagchi MK, Tsai SY, Weigel NL, Tsai MJ, O'Malley BW. Regulation of in vitro transcription by progesterone receptor. Characterization and kinetic studies. J Biol Chem. 1990 Mar 25; 265(9):5129-34. PMID: 2318886.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    206. Klein-Hitpass L, Tsai SY, Weigel NL, Allan GF, Riley D, Rodriguez R, Schrader WT, Tsai MJ, O'Malley BW. The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex. Cell. 1990 Jan 26; 60(2):247-57. PMID: 2153462.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    207. Pastorcic M, Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Multiple protein binding sites within the ovalbumin gene 5'-flanking region: isolation and characterization of sequence-specific binding proteins. Nucleic Acids Res. 1989 Aug 25; 17(16):6693-711. PMID: 2780293.
      Citations: 3     Fields:    Translation:AnimalsCells
    208. Wang LH, Tsai SY, Cook RG, Beattie WG, Tsai MJ, O'Malley BW. COUP transcription factor is a member of the steroid receptor superfamily. Nature. 1989 Jul 13; 340(6229):163-6. PMID: 2739739.
      Citations: 142     Fields:    Translation:AnimalsCells
    209. Tsai SY, Tsai MJ, O'Malley BW. Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements. Cell. 1989 May 05; 57(3):443-8. PMID: 2566384.
      Citations: 85     Fields:    Translation:AnimalsCells
    210. Klein-Hitpass L, Tsai SY, Greene GL, Clark JH, Tsai MJ, O'Malley BW. Specific binding of estrogen receptor to the estrogen response element. Mol Cell Biol. 1989 Jan; 9(1):43-9. PMID: 2927397.
      Citations: 41     Fields:    Translation:AnimalsCells
    211. Bagchi MK, Elliston JF, Tsai SY, Edwards DP, Tsai MJ, O'Malley BW. Steroid hormone-dependent interaction of human progesterone receptor with its target enhancer element. Mol Endocrinol. 1988 Dec; 2(12):1221-9. PMID: 3216861.
      Citations: 16     Fields:    Translation:HumansCells
    212. Tsai SY, Carlstedt-Duke J, Weigel NL, Dahlman K, Gustafsson JA, Tsai MJ, O'Malley BW. Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation. Cell. 1988 Oct 21; 55(2):361-9. PMID: 3167984.
      Citations: 126     Fields:    Translation:AnimalsCells
    213. Li Y, Shen RF, Tsai SY, Woo SL. Multiple hepatic trans-acting factors are required for in vitro transcription of the human alpha-1-antitrypsin gene. Mol Cell Biol. 1988 Oct; 8(10):4362-9. PMID: 3263567.
      Citations: 16     Fields:    Translation:AnimalsCells
    214. Hwung YP, Wang LH, Tsai SY, Tsai MJ. Differential binding of the chicken ovalbumin upstream promoter (COUP) transcription factor to two different promoters. J Biol Chem. 1988 Sep 15; 263(26):13470-4. PMID: 3047126.
      Citations: 14     Fields:    Translation:Cells
    215. Hwung YP, Crowe DT, Wang LH, Tsai SY, Tsai MJ. The COUP transcription factor binds to an upstream promoter element of the rat insulin II gene. Mol Cell Biol. 1988 May; 8(5):2070-7. PMID: 3290646.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    216. Tsai MJ, Tsai SY, Klein-Hitpass L, Bagchi M, Elliston JF, Carlstedt-Duke J, Gustafsson JA, Gustafsson JK, O'Malley BW. Cooperative interactions of steroid hormone receptors with their cognate response elements. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 2:829-33. PMID: 3254786.
      Citations:    Fields:    Translation:AnimalsCells
    217. Wang LH, Tsai SY, Wang H, Sagami I, Tsai MJ, O'Malley BW. The studies of COUP transcription factor from HeLa cells: purification and partial characterization. Prog Clin Biol Res. 1988; 284:37-51. PMID: 3217427.
      Citations:    Fields:    Translation:HumansAnimalsCells
    218. Crowe DT, Hwung YP, Tsai SY, Tsai MJ. Characterization of the cis and trans elements essential for rat insulin II gene expression. Prog Clin Biol Res. 1988; 284:211-24. PMID: 3064102.
      Citations: 1     Fields:    Translation:AnimalsCells
    219. Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Purification and characterization of chicken ovalbumin gene upstream promoter transcription factor from homologous oviduct cells. Mol Cell Biol. 1987 Dec; 7(12):4151-8. PMID: 3437886.
      Citations: 19     Fields:    Translation:AnimalsCells
    220. Wang LH, Tsai SY, Sagami I, Tsai MJ, O'Malley BW. Purification and characterization of chicken ovalbumin upstream promoter transcription factor from HeLa cells. J Biol Chem. 1987 Nov 25; 262(33):16080-6. PMID: 3680243.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    221. Shen RF, Li Y, Sifers RN, Wang H, Hardick C, Tsai SY, Woo SL. Tissue-specific expression of the human alpha 1-antitrypsin gene is controlled by multiple cis-regulatory elements. Nucleic Acids Res. 1987 Oct 26; 15(20):8399-415. PMID: 2823229.
      Citations: 19     Fields:    Translation:HumansCells
    222. Tsai MJ, Schwartz RJ, Tsai SY, O'Malley BW . Effect of estrogen on gene expression in the chick oviduct IV. Initiation of RNA synthesis on DNA and chromatin. 1975; 250(13):5165-5174.
    223. Schwartz RJ, Tsai MJ, Tsai SY, O'Malley BW . Effect of estrogen on gene expression in the chick oviduct V. Changes in the number of RNA polymerase binding and initiation sites in chromatin. 1975; 250(13):5175-5182.
    224. Tsai S, Arlinghaus RB. Formation of mengovirus-like particles in cell-free extracts from virus-infected cells. Biochem Biophys Res Commun. 1974 Apr 08; 57(3):733-9. PMID: 4363940.
      Citations:    Fields:    Translation:AnimalsCells
    225. Naso WANG CS, Tsai S, Arlinghaus RB. Ribosomes from Rauscher leukemia virus-infected cells and their response to Rauscher viral RNA and polyuridylic acid. Biochim Biophys Acta. 1973 Oct 26; 324(3):346-64. PMID: 4762415.
      Citations: 5     Fields:    Translation:AnimalsCells
    226. Yang S, Criddle RS. In vitro biosynthesis of membrane proteins in isolated mitochondria from Saccharomyces carlsbergensis. Biochemistry. 1970 Jul 21; 9(15):3063-72. PMID: 5474805.
      Citations: 14     Fields:    Translation:AnimalsCells
    227. Yang S, Criddle RS. Identification of a major membrane fraction as a product of synthesis by isolated yeast mitochondria. Biochem Biophys Res Commun. 1969 May 22; 35(4):429-36. PMID: 5788500.
      Citations: 2     Fields:    Translation:AnimalsCells
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