"Ubiquitination" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The act of ligating UBIQUITINS to PROTEINS to form ubiquitin-protein ligase complexes to label proteins for transport to the PROTEASOME ENDOPEPTIDASE COMPLEX where proteolysis occurs.
| Descriptor ID |
D054875
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| MeSH Number(s) |
G02.111.660.871.790.600.925 G02.111.691.600.775 G03.734.871.790.600.831 G05.308.670.600.831
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ubiquitination".
Below are MeSH descriptors whose meaning is more specific than "Ubiquitination".
This graph shows the total number of publications written about "Ubiquitination" by people in this website by year, and whether "Ubiquitination" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 4 | 9 | 13 |
| 2008 | 6 | 12 | 18 |
| 2009 | 8 | 24 | 32 |
| 2010 | 7 | 20 | 27 |
| 2011 | 7 | 23 | 30 |
| 2012 | 5 | 25 | 30 |
| 2013 | 6 | 18 | 24 |
| 2014 | 4 | 17 | 21 |
| 2015 | 2 | 20 | 22 |
| 2016 | 5 | 12 | 17 |
| 2017 | 6 | 13 | 19 |
| 2018 | 5 | 12 | 17 |
| 2019 | 3 | 18 | 21 |
| 2020 | 2 | 16 | 18 |
| 2021 | 3 | 8 | 11 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 4 | 4 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ubiquitination" by people in Profiles.
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Post-ischemic ubiquitination at the postsynaptic density reversibly influences the activity of ischemia-relevant kinases. Commun Biol. 2024 Mar 13; 7(1):321.
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SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8+ T cells. Sci Transl Med. 2023 09 13; 15(713):eade2581.
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Lysosome-dependent FOXA1 ubiquitination contributes to luminal lineage of advanced prostate cancer. Mol Oncol. 2023 10; 17(10):2126-2146.
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TRAF4-mediated nonproteolytic ubiquitination of androgen receptor promotes castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2023 05 16; 120(20):e2218229120.
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PD-L1 translocation to the plasma membrane enables tumor immune evasion through MIB2 ubiquitination. J Clin Invest. 2023 02 01; 133(3).
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USP7 substrates identified by proteomics analysis reveal the specificity of USP7. Genes Dev. 2022 09 01; 36(17-18):1016-1030.
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The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice. BMC Biol. 2022 07 13; 20(1):161.
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A gene signature consisting of ubiquitin ligases and deubiquitinating enzymes of SKP2 is associated with clinical outcome in breast cancer. Sci Rep. 2022 02 15; 12(1):2478.
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Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity. Nat Commun. 2021 11 25; 12(1):6896.
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Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination. Cell Rep. 2021 10 26; 37(4):109904.