"Methylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Addition of methyl groups. In histo-chemistry methylation is used to esterify carboxyl groups and remove sulfate groups by treating tissue sections with hot methanol in the presence of hydrochloric acid. (From Stedman, 25th ed)
| Descriptor ID |
D008745
|
| MeSH Number(s) |
G02.111.035.538 G02.607.094.538 G03.059.538
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Methylation".
Below are MeSH descriptors whose meaning is more specific than "Methylation".
This graph shows the total number of publications written about "Methylation" by people in this website by year, and whether "Methylation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 5 | 5 |
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 5 | 5 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 4 | 4 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 6 | 6 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 9 | 9 |
| 2004 | 0 | 7 | 7 |
| 2005 | 1 | 14 | 15 |
| 2006 | 0 | 23 | 23 |
| 2007 | 1 | 19 | 20 |
| 2008 | 0 | 6 | 6 |
| 2009 | 0 | 16 | 16 |
| 2010 | 0 | 22 | 22 |
| 2011 | 0 | 16 | 16 |
| 2012 | 1 | 19 | 20 |
| 2013 | 0 | 18 | 18 |
| 2014 | 0 | 13 | 13 |
| 2015 | 1 | 19 | 20 |
| 2016 | 0 | 21 | 21 |
| 2017 | 1 | 15 | 16 |
| 2018 | 0 | 17 | 17 |
| 2019 | 0 | 13 | 13 |
| 2020 | 1 | 11 | 12 |
| 2021 | 0 | 12 | 12 |
| 2022 | 0 | 4 | 4 |
| 2023 | 0 | 9 | 9 |
| 2024 | 0 | 6 | 6 |
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Below are the most recent publications written about "Methylation" by people in Profiles.
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SMYD5 is a regulator of the mild hypothermia response. Cell Rep. 2024 Aug 27; 43(8):114554.
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SMYD5 methylation of rpL40 links ribosomal output to gastric cancer. Nature. 2024 Aug; 632(8025):656-663.
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SETD3 is a mechanosensitive enzyme that methylates actin on His73 to regulate mitochondrial dynamics and function. J Cell Sci. 2024 07 15; 137(14).
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SART3 reads methylarginine-marked glycine- and arginine-rich motifs. Cell Rep. 2024 Jul 23; 43(7):114459.
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Histone H3K18 & H3K23 acetylation directs establishment of MLL-mediated H3K4 methylation. J Biol Chem. 2024 Aug; 300(8):107527.
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Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity. Nat Cancer. 2024 Apr; 5(4):601-624.
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Molecular Basis for SPINDOC-Spindlin1 Engagement and Its Role in Transcriptional Attenuation. J Mol Biol. 2024 Apr 01; 436(7):168371.
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Rare de novo gain-of-function missense variants in DOT1L are associated with developmental delay and congenital anomalies. Am J Hum Genet. 2023 11 02; 110(11):1919-1937.
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Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation. Nat Methods. 2023 10; 20(10):1483-1492.
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H3K36 methylation maintains cell identity by regulating opposing lineage programmes. Nat Cell Biol. 2023 Aug; 25(8):1121-1134.