"Genes, Tumor Suppressor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.
| Descriptor ID |
D016147
|
| MeSH Number(s) |
G05.360.340.024.340.375.249 G05.360.340.024.340.415.400
|
| Concept/Terms |
Genes, Tumor Suppressor- Genes, Tumor Suppressor
- Gene, Tumor Suppressor
- Tumor Suppressor Gene
- Antioncogenes
- Antioncogene
- Emerogenes
- Emerogene
- Genes, Onco-Suppressor
- Gene, Onco-Suppressor
- Genes, Onco Suppressor
- Onco-Suppressor Gene
- Onco-Suppressor Genes
- Cancer Suppressor Genes
- Cancer Suppressor Gene
- Gene, Cancer Suppressor
- Suppressor Gene, Cancer
- Suppressor Genes, Cancer
- Oncogenes, Recessive
- Oncogene, Recessive
- Recessive Oncogene
- Recessive Oncogenes
- Anti-Oncogenes
- Anti Oncogenes
- Anti-Oncogene
- Tumor Suppressing Genes
- Gene, Tumor Suppressing
- Genes, Tumor Suppressing
- Tumor Suppressing Gene
- Genes, Cancer Suppressor
- Tumor Suppressor Genes
Metastasis Suppressor Genes- Metastasis Suppressor Genes
- Gene, Metastasis Suppressor
- Metastasis Suppressor Gene
- Suppressor Gene, Metastasis
- Suppressor Genes, Metastasis
- Genes, Metastasis Suppressor
Growth Suppressor Genes- Growth Suppressor Genes
- Gene, Growth Suppressor
- Growth Suppressor Gene
- Suppressor Gene, Growth
- Suppressor Genes, Growth
- Genes, Growth Suppressor
|
Below are MeSH descriptors whose meaning is more general than "Genes, Tumor Suppressor".
Below are MeSH descriptors whose meaning is more specific than "Genes, Tumor Suppressor".
- Genes, Tumor Suppressor
- Genes, APC
- Genes, BRCA1
- Genes, BRCA2
- Genes, DCC
- Genes, MCC
- Genes, Neurofibromatosis 1
- Genes, Neurofibromatosis 2
- Genes, p16
- Genes, p53
- Genes, Retinoblastoma
- Genes, Wilms Tumor
This graph shows the total number of publications written about "Genes, Tumor Suppressor" by people in this website by year, and whether "Genes, Tumor Suppressor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 8 | 4 | 12 |
| 1995 | 10 | 2 | 12 |
| 1996 | 8 | 13 | 21 |
| 1997 | 10 | 10 | 20 |
| 1998 | 30 | 16 | 46 |
| 1999 | 19 | 18 | 37 |
| 2000 | 16 | 13 | 29 |
| 2001 | 24 | 30 | 54 |
| 2002 | 17 | 36 | 53 |
| 2003 | 18 | 29 | 47 |
| 2004 | 8 | 32 | 40 |
| 2005 | 12 | 30 | 42 |
| 2006 | 12 | 12 | 24 |
| 2007 | 12 | 10 | 22 |
| 2008 | 9 | 14 | 23 |
| 2009 | 8 | 10 | 18 |
| 2010 | 8 | 16 | 24 |
| 2011 | 8 | 11 | 19 |
| 2012 | 8 | 12 | 20 |
| 2013 | 6 | 5 | 11 |
| 2014 | 8 | 10 | 18 |
| 2015 | 4 | 6 | 10 |
| 2016 | 2 | 5 | 7 |
| 2017 | 3 | 9 | 12 |
| 2018 | 3 | 5 | 8 |
| 2019 | 3 | 1 | 4 |
| 2020 | 2 | 6 | 8 |
| 2021 | 1 | 2 | 3 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 5 | 5 |
To return to the timeline,
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Below are the most recent publications written about "Genes, Tumor Suppressor" by people in Profiles.
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EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes. Cancer Res. 2023 12 01; 83(23):3956-3973.
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A novel LINC00478 serves as a tumor suppressor in endometrial carcinoma progression. J Cancer Res Clin Oncol. 2023 Nov; 149(16):14927-14940.
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Comprehensive molecular characterization of adenoid cystic carcinoma reveals tumor suppressors as novel drivers and prognostic biomarkers. J Pathol. 2023 11; 261(3):256-268.
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The deleted in oral cancer (DOC1 aka CDK2AP1) tumor suppressor gene is downregulated in oral squamous cell carcinoma by multiple microRNAs. Cell Death Dis. 2023 05 22; 14(5):337.
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Multiplatform Analysis of Intratumoral PTEN Heterogeneity in Melanoma. J Invest Dermatol. 2023 09; 143(9):1779-1787.e1.
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TUSC2 immunogene enhances efficacy of chemo-immuno combination on KRAS/LKB1 mutant NSCLC in humanized mouse model. Commun Biol. 2022 02 24; 5(1):167.
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Epigenetic Silencing of Tumor Suppressor lncRNA NKILA: Implication on NF-?B Signaling in Non-Hodgkin's Lymphoma. Genes (Basel). 2022 01 11; 13(1).
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Tumor suppressor function of WT1 in acute promyelocytic leukemia. Haematologica. 2022 01 01; 107(1):342-346.
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Tumor suppressor PLK2 may serve as a biomarker in triple-negative breast cancer for improved response to PLK1 therapeutics. Cancer Res Commun. 2021 12; 1(3):178-193.
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The immunogenomic landscape of resected intrahepatic cholangiocarcinoma. Hepatology. 2022 02; 75(2):297-308.