"Genes, DCC" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tumor suppressor genes located in the 18q21-qter region of human chromosome 18. The absence of these genes is associated with the formation of colorectal cancer (DCC stands for deleted in colorectal cancer). The products of these genes show significant homology to neural cell adhesion molecules and other related cell surface glycoproteins.
| Descriptor ID |
D016163
|
| MeSH Number(s) |
G05.360.340.024.340.375.249.200 G05.360.340.024.340.415.400.200
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| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Genes, DCC".
Below are MeSH descriptors whose meaning is more specific than "Genes, DCC".
This graph shows the total number of publications written about "Genes, DCC" by people in this website by year, and whether "Genes, DCC" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, DCC" by people in Profiles.
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Chromosome 18 breakpoint in t(11;18)(q21;q21) translocation associated with MALT lymphoma is proximal to BCL2 and distal to DCC. Genes Chromosomes Cancer. 1999 Feb; 24(2):156-9.
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Status of deleted in colorectal cancer gene expression correlates with neuroblastoma metastasis. Lab Invest. 1998 Jun; 78(6):669-75.
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Decreased expression of the deleted in colorectal carcinoma gene in non-Hodgkin's lymphoma. Blood. 1995 May 15; 85(10):2813-6.