"Steroidogenic Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor and member of the nuclear receptor family NR5 that is expressed throughout the adrenal and reproductive axes during development. It plays an important role in sexual differentiation, formation of primary steroidogenic tissues, and their functions in post-natal and adult life. It regulates the expression of key steroidogenic enzymes.
| Descriptor ID |
D054339
|
| MeSH Number(s) |
D12.776.826.925
|
| Concept/Terms |
Steroidogenic Factor 1- Steroidogenic Factor 1
- Ad4-Binding Protein
- Ad4 Binding Protein
- Adrenal 4 Binding Protein
- AD4BP Protein
- Fushi Tarazu Factor Homolog 1
- NR5A1 Protein
- Nuclear Receptor 5A1 Protein
- FTZF1 Protein
- SF-1 Transcription Factor
- Transcription Factor, SF-1
- Steroid Hormone Receptor Ad4BP
|
Below are MeSH descriptors whose meaning is more general than "Steroidogenic Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Steroidogenic Factor 1".
This graph shows the total number of publications written about "Steroidogenic Factor 1" by people in this website by year, and whether "Steroidogenic Factor 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Steroidogenic Factor 1" by people in Profiles.
-
PIT-1/SF-1 co-expression in pituitary neuroendocrine tumors (PitNETs) with comprehensive review of the literature: How should we best characterize these neoplasms? Ann Diagn Pathol. 2025 Feb; 74:152398.
-
Rap1 in the VMH regulates glucose homeostasis. JCI Insight. 2021 06 08; 6(11).
-
Undifferentiated spermatogonia regulate Cyp26b1 expression through NOTCH signaling and drive germ cell differentiation. FASEB J. 2019 07; 33(7):8423-8435.
-
A recurrent p.Arg92Trp variant in steroidogenic factor-1 (NR5A1) can act as a molecular switch in human sex development. Hum Mol Genet. 2016 08 15; 25(16):3446-3453.
-
Value of PAX-8 and SF-1 Immunohistochemistry in the Distinction Between Female Adnexal Tumor of Probable Wolffian Origin and its Mimics. Int J Gynecol Pathol. 2016 Mar; 35(2):167-75.
-
Molecular biology of endometriosis: from aromatase to genomic abnormalities. Semin Reprod Med. 2015 May; 33(3):220-4.
-
Screening and familial characterization of copy-number variations in NR5A1 in 46,XY disorders of sex development and premature ovarian failure. Am J Med Genet A. 2013 Oct; 161A(10):2487-94.
-
Genetic and epigenetic alterations of steroidogenic factor-1 in ovarian tumors. Int J Oncol. 2013 Feb; 42(2):627-34.
-
Steroid receptor coactivator-1 mediates estrogenic actions to prevent body weight gain in female mice. Endocrinology. 2013 Jan; 154(1):150-8.
-
FOXO1 in the ventromedial hypothalamus regulates energy balance. J Clin Invest. 2012 Jul; 122(7):2578-89.