"Cephalexin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A semisynthetic cephalosporin antibiotic with antimicrobial activity similar to that of CEPHALORIDINE or CEPHALOTHIN, but somewhat less potent. It is effective against both gram-positive and gram-negative organisms.
| Descriptor ID |
D002506
|
| MeSH Number(s) |
D02.065.589.099.249.200 D02.886.665.074.200 D03.633.100.300.249.200
|
| Concept/Terms |
Cephalexin- Cephalexin
- Cephalexin Monohydrate
- Monohydrate, Cephalexin
- Cefalexin
Cephalexin Hydrochloride- Cephalexin Hydrochloride
- Hydrochloride, Cephalexin
- Cephalexin Monohydrochloride, Monohydrate
- Monohydrate Cephalexin Monohydrochloride
- Monohydrochloride, Monohydrate Cephalexin
|
Below are MeSH descriptors whose meaning is more general than "Cephalexin".
Below are MeSH descriptors whose meaning is more specific than "Cephalexin".
This graph shows the total number of publications written about "Cephalexin" by people in this website by year, and whether "Cephalexin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cephalexin" by people in Profiles.
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QM/MM modeling of class A ?-lactamases reveals distinct acylation pathways for ampicillin and cefalexin. Org Biomol Chem. 2021 Nov 03; 19(42):9182-9189.
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Pyoderma gangrenosum following patellar tendon repair: a case report and review of the literature. Am J Orthop (Belle Mead NJ). 2012 Jan; 41(1):E4-9.
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Structural and biochemical evidence that a TEM-1 beta-lactamase N170G active site mutant acts via substrate-assisted catalysis. J Biol Chem. 2009 Nov 27; 284(48):33703-12.
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Fatal cephalosporin-induced acute hypersensitivity myocarditis. Pediatr Cardiol. 2006 Nov-Dec; 27(6):777-80.
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Epstein-Barr virus dacryoadenitis. Am J Ophthalmol. 2000 Mar; 129(3):372-5.
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Uptake characteristics of loracarbef and cephalexin in the Caco-2 cell culture model: effects of the proton gradient and possible presence of a distinctive second component. J Pharm Sci. 1996 Jul; 85(7):767-72.
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Mechanisms of transport of quinapril in Caco-2 cell monolayers: comparison with cephalexin. Pharm Res. 1995 Aug; 12(8):1120-5.
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Chemoprophylaxis of dental patients with prosthetic joints: a simulation model. J Dent Educ. 1988 Nov; 52(11):599-604.
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The cephalosporin antibiotics: Results of laboratory and clinical studies in 312 infants and children. J Okla State Med Assoc. 1977 Sep; 70(9):388-401.