"Lactones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cyclic esters of hydroxy carboxylic acids, containing a 1-oxacycloalkan-2-one structure. Large cyclic lactones of over a dozen atoms are MACROLIDES.
| Descriptor ID |
D007783
|
| MeSH Number(s) |
D02.540
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lactones".
Below are MeSH descriptors whose meaning is more specific than "Lactones".
This graph shows the total number of publications written about "Lactones" by people in this website by year, and whether "Lactones" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1997 | 1 | 1 | 2 |
| 1998 | 0 | 2 | 2 |
| 1999 | 2 | 0 | 2 |
| 2000 | 2 | 0 | 2 |
| 2001 | 1 | 2 | 3 |
| 2002 | 3 | 1 | 4 |
| 2003 | 2 | 2 | 4 |
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2006 | 6 | 1 | 7 |
| 2007 | 2 | 2 | 4 |
| 2008 | 1 | 0 | 1 |
| 2009 | 2 | 3 | 5 |
| 2011 | 4 | 1 | 5 |
| 2012 | 1 | 2 | 3 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 2 | 2 | 4 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 2 | 3 |
| 2019 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Lactones" by people in Profiles.
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Biochemical Characterization and Application of Zearalenone Lactone Hydrolase Fused with a Multifunctional Short Peptide. J Agric Food Chem. 2024 Aug 14; 72(32):18146-18154.
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Activation of Munc13-1 by Diacylglycerol (DAG)-Lactones. Biochemistry. 2023 09 19; 62(18):2717-2726.
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Controlled lipid ?-oxidation and carnitine biosynthesis by a vitamin D metabolite. Cell Chem Biol. 2022 04 21; 29(4):660-669.e12.
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Development of Rofecoxib-Based Fluorescent Probes and Investigations on Their Solvatochromism, AIE Activity, Mechanochromism, and COX-2-Targeted Bioimaging. Anal Chem. 2021 09 07; 93(35):11991-12000.
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One-Step Transformation from Rofecoxib to a COX-2 NIR Probe for Human Cancer Tissue/Organoid Targeted Bioimaging. ACS Appl Bio Mater. 2021 03 15; 4(3):2723-2731.
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Rofecoxib and Clinically Significant Gastrointestinal Events: Response. Am J Med Sci. 2019 09; 358(3):e9-e10.
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Stereoselective Synthesis of Four Calcitriol Lactone Diastereomers at C23 and C25. J Org Chem. 2019 06 21; 84(12):7630-7641.
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Anti-tumor and anti-metastasis efficacy of E6201, a MEK1 inhibitor, in preclinical models of triple-negative breast cancer. Breast Cancer Res Treat. 2019 Jun; 175(2):339-351.
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Ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) assay for simultaneous quantifications of CZ48, lactone-stabilized camptothecin, and camptothecin and their pharmacokinetic and biliary evaluations in rats. J Pharm Biomed Anal. 2018 Nov 30; 161:122-128.
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Effects of genetic variation in protease activated receptor 4 after an acute coronary syndrome: Analysis from the TRACER trial. Blood Cells Mol Dis. 2018 09; 72:37-43.