"Tryptophan Hydroxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the hydroxylation of TRYPTOPHAN to 5-HYDROXYTRYPTOPHAN in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of SEROTONIN.
| Descriptor ID |
D014365
|
| MeSH Number(s) |
D08.811.682.690.708.870
|
| Concept/Terms |
Tryptophan Hydroxylase- Tryptophan Hydroxylase
- Hydroxylase, Tryptophan
- Tryptophan Monooxygenase
- Monooxygenase, Tryptophan
|
Below are MeSH descriptors whose meaning is more general than "Tryptophan Hydroxylase".
Below are MeSH descriptors whose meaning is more specific than "Tryptophan Hydroxylase".
This graph shows the total number of publications written about "Tryptophan Hydroxylase" by people in this website by year, and whether "Tryptophan Hydroxylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 3 | 0 | 3 |
| 1998 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 2 | 2 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Tryptophan Hydroxylase" by people in Profiles.
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TPH2 in the Dorsal Raphe Nuclei Regulates Energy Balance in a Sex-Dependent Manner. Endocrinology. 2021 01 01; 162(1).
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Sensation-seeking genes and physical activity in youth. Genes Brain Behav. 2013 Mar; 12(2):181-8.
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Activation of mu-opioid receptors inhibits synaptic inputs to spinally projecting rostral ventromedial medulla neurons. J Pharmacol Exp Ther. 2004 May; 309(2):476-83.
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Undernutrition and the development of brain neurotransmitter systems. Life Sci. 1984 Nov 19; 35(21):2085-94.