"Receptors, Opioid, mu" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of opioid receptors recognized by its pharmacological profile. Mu opioid receptors bind, in decreasing order of affinity, endorphins, dynorphins, met-enkephalin, and leu-enkephalin. They have also been shown to be molecular receptors for morphine.
| Descriptor ID |
D017450
|
| MeSH Number(s) |
D12.776.543.750.695.620.550 D12.776.543.750.720.600.610.550 D12.776.543.750.750.555.610.550
|
| Concept/Terms |
Receptors, Opioid, mu- Receptors, Opioid, mu
- Opioid Receptors, mu
- mu Opioid Receptors
- Receptors, mu Opioid
- Receptors, mu
- mu Receptor
- Receptor, mu
- mu Receptors
- mu Opioid Receptor
- Opioid Receptor, mu
- Receptor, mu Opioid
Morphine Receptor- Morphine Receptor
- Receptor, Morphine
- Receptors, Morphine
- Morphine Receptors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Opioid, mu".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Opioid [D12.776.543.750.695.620]
- Receptors, Opioid, mu [D12.776.543.750.695.620.550]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Opioid [D12.776.543.750.720.600.610]
- Receptors, Opioid, mu [D12.776.543.750.720.600.610.550]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Opioid [D12.776.543.750.750.555.610]
- Receptors, Opioid, mu [D12.776.543.750.750.555.610.550]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Opioid, mu".
This graph shows the total number of publications written about "Receptors, Opioid, mu" by people in this website by year, and whether "Receptors, Opioid, mu" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 1 | 1 | 2 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 2 | 4 |
| 2010 | 1 | 1 | 2 |
| 2012 | 1 | 1 | 2 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
| 2025 | 2 | 0 | 2 |
| 2026 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, Opioid, mu" by people in Profiles.
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A ?-opioid receptor superagonist analgesic with minimal adverse effects. Nature. 2026 Apr; 652(8112):1393-1404.
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Non-equilibrium snapshots of ligand efficacy at the ?-opioid receptor. Nature. 2026 04; 652(8110):794-802.
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A putative binding model of nitazene derivatives at the ?-opioid receptor. Neuropharmacology. 2025 08 01; 273:110437.
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Nerve injury inhibits Oprd1 and Cnr1 transcription through REST in primary sensory neurons. Sci Rep. 2024 11 04; 14(1):26612.
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Effect of Selective Lesions of Nucleus Accumbens ?-Opioid Receptor-Expressing Cells on Heroin Self-Administration in Male and Female Rats: A Study with Novel Oprm1-Cre Knock-in Rats. J Neurosci. 2023 03 08; 43(10):1692-1713.
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Structure-based design of bitopic ligands for the ?-opioid receptor. Nature. 2023 01; 613(7945):767-774.
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Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response. Nat Commun. 2019 09 09; 10(1):4075.
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Activation of Astrocytic ?-Opioid Receptor Causes Conditioned Place Preference. Cell Rep. 2019 07 30; 28(5):1154-1166.e5.
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Neurobiology of Opioid Use Disorder and Comorbid Traumatic Brain Injury. JAMA Psychiatry. 2018 06 01; 75(6):642-648.
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Epigenetic variation in OPRM1 gene in opioid-exposed mother-infant dyads. Genes Brain Behav. 2018 09; 17(7):e12476.