DAVID RANDALL GROSSHANS

TitleAssociate Professor
InstitutionMD Anderson
DepartmentRadiation Oncology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Guan F, Bronk L, Kerr M, Li Y, Braby LA, Sobieski M, Wang X, Zhang X, Stephan C, Grosshans DR, Mohan R. Interpreting the biological effects of protons as a function of physical quantity: linear energy transfer or microdosimetric lineal energy spectrum? Sci Rep. 2024 10 24; 14(1):25181. PMID: 39448656; PMCID: PMC11502811.
      Citations:    Fields:    Translation:HumansCells
    2. Abu-Arja MH, Brown AL, Su JM, Okcu MF, Lindsay HB, McGovern SL, McAleer MF, Grosshans DR, Chintagumpala MM, Paulino AC, Abu-Arja MH, Brown AL, Su JM, Okcu MF, Lindsay HB, McGovern SL, McAleer MF, Grosshans DR, Chintagumpala MM, Paulino AC. The cochlear dose and the age at radiotherapy predict severe hearing loss after passive scattering proton therapy and cisplatin in children with medulloblastoma. Neuro Oncol. 2024 Oct 03; 26(10):1912-1920. PMID: 38916058; PMCID: PMC11449093.
      Citations:    Fields:    Translation:Humans
    3. Guan F, Jiang D, Wang X, Yang M, Iga K, Li Y, Bronk L, Bronk J, Wang L, Guo Y, Sahoo N, Grosshans DR, Koong AC, Zhu XR, Mohan R. Mimicking large spot-scanning radiation fields for proton FLASH preclinical studies with a robotic motion platform. ArXiv. 2024 Sep 14. PMID: 39314510; PMCID: PMC11419177.
      Citations:    
    4. Chen M, Yang D, Zhu XR, Ma L, Grosshans DR, Shao Y, Lu W, Chen M, Yang D, Zhu XR, Ma L, Grosshans DR, Shao Y, Lu W. Investigation of intra-fractionated range guided adaptive proton therapy (RGAPT): II. Range-shift compensated on-line treatment adaptation and verification. Phys Med Biol. 2024 Jul 17; 69(15). PMID: 38861995.
      Citations:    Fields:    Translation:Humans
    5. Yang D, Zhu XR, Chen M, Ma L, Cheng X, Grosshans DR, Lu W, Shao Y, Yang D, Zhu XR, Chen M, Ma L, Cheng X, Grosshans DR, Lu W, Shao Y. Investigation of intra-fractionated range guided adaptive proton therapy: I. On-line PET imaging and range measurement. Phys Med Biol. 2024 Jul 17; 69(15). PMID: 38861997.
      Citations:    Fields:    Translation:Humans
    6. Kim M, Maldonado JA, Pandey P, El Alam MB, Kouzy R, Christopherson K, Minsky BD, Nugyen QN, Grosshans D, Lin LL, Mitchell MP, Klopp AH, Lee PP, Bird J, Satcher R, Lewis VO, Lin PP, Tang C, Koong AC, Moon B, Colbert LE. Single-fraction radiation retreatment for bone metastases: role of a rapid access clinic. BMJ Support Palliat Care. 2024 Jun 06. PMID: 38843933.
      Citations:    Fields:    
    7. Wang C, Rooney MK, Alvarez-Breckenridge C, Beckham TH, Chung C, De BS, Ghia AJ, Grosshans D, Majd NK, McAleer MF, McGovern SL, North RY, Paulino AC, Perni S, Reddy JP, Rhines LD, Swanson TA, Tatsui CE, Tom MC, Yeboa DN, Li J. Outcomes and Pattern of Care for Spinal Myxopapillary Ependymoma in the Modern Era-A Population-Based Observational Study. Cancers (Basel). 2024 May 25; 16(11). PMID: 38893133; PMCID: PMC11171081.
      Citations:    
    8. Bronk JK, McAleer MF, McGovern SL, Lassen-Ramshad Y, Safwat A, Daw NC, Rainusso N, Mahajan A, Grosshans DR, Paulino AC. Comprehensive radiotherapy for pediatric Ewing Sarcoma: Outcomes of a prospective proton study. Radiother Oncol. 2024 06; 195:110270. PMID: 38583721.
      Citations: 1     Fields:    Translation:Humans
    9. Grosshans D, Thomas R, Zhang D, Cronkite C, Thomas R, Singh S, Bronk L, Morales R, Duman J. Subcellular functions of tau mediates repair response and synaptic homeostasis in injury. Res Sq. 2024 Feb 29. PMID: 38464175; PMCID: PMC10925419.
      Citations:    
    10. Beckham TH, Rooney MK, McAleer MF, Ghia AJ, Tom MC, Perni S, McGovern S, Grosshans D, Chung C, Wang C, De B, Swanson T, Paulino A, Jiang W, Ferguson S, Patel CB, Li J, Yeboa DN. Hypofractionated radiotherapy for glioblastoma: A large institutional retrospective assessment of 2 approaches. Neurooncol Pract. 2024 Jun; 11(3):266-274. PMID: 38737610; PMCID: PMC11085842.
      Citations:    
    11. Guan F, Zhao L, Bronk JK, Maletic-Savatic M, Grosshans DR, Carlson DJ. Editorial: Advances in the biological effects of ionizing radiation. Front Oncol. 2023; 13:1352771. PMID: 38234403; PMCID: PMC10793655.
      Citations:    
    12. Wefel JS, Deshmukh S, Brown PD, Grosshans DR, Sulman EP, Cerhan JH, Mehta MP, Khuntia D, Shi W, Mishra MV, Suh JH, Laack NN, Chen Y, Curtis AA, Laba JM, Elsayed A, Thakrar A, Pugh SL, Bruner DW. Impact of Apolipoprotein E Genotype on Neurocognitive Function in Patients With Brain Metastases: An Analysis of NRG Oncology's RTOG 0614. Int J Radiat Oncol Biol Phys. 2024 Jul 01; 119(3):846-857. PMID: 38101486; PMCID: PMC11162903.
      Citations: 2     Fields:    Translation:Humans
    13. Sienna J, Kahalley LS, Mabbott D, Grosshans D, Santiago AT, Paulino ADC, Merchant TE, Manzar GS, Dama H, Hodgson DC, Chintagumpala M, Okcu MF, Whitehead WE, Laperriere N, Ramaswamy V, Bartels U, Tabori U, Bennett JM, Das A, Craig T, Tsang DS. Proton Therapy Mediates Dose Reductions to Brain Structures Associated With Cognition in Children With Medulloblastoma. Int J Radiat Oncol Biol Phys. 2024 May 01; 119(1):200-207. PMID: 38040059; PMCID: PMC11023754.
      Citations:    Fields:    
    14. Goudarzi HM, Lim G, Grosshans D, Mohan R, Cao W. Incorporating variable RBE in IMPT optimization for ependymoma. J Appl Clin Med Phys. 2024 Jan; 25(1):e14207. PMID: 37985962; PMCID: PMC10795446.
      Citations: 1     Fields:    Translation:HumansCells
    15. Durante M, Bender T, Schickel E, Mayer M, Debus J, Grosshans D, Schroeder I. Aberrant choroid plexus formation in human cerebral organoids exposed to radiation. Res Sq. 2023 Oct 17. PMID: 37886443; PMCID: PMC10602134.
      Citations:    
    16. Rubino F, Brahimaj B, Hanna EY, Su SY, Phan J, Grosshans DR, DeMonte F, Raza SM. Does Time to Initiation of Adjuvant Radiotherapy Affect Reconstruction Outcomes after Endoscopic Resection of Skull Base Malignancies? J Neurol Surg B Skull Base. 2024 Oct; 85(5):445-457. PMID: 39228888; PMCID: PMC11368463.
      Citations:    
    17. Matsui JK, Allen PK, Perlow HK, Johnson JM, Paulino AC, McAleer MF, Fouladi M, Grosshans DR, Ghia AJ, Li J, Zaky WT, Chintagumpala MM, Palmer JD, McGovern SL. Prognostic factors for pediatric, adolescent, and young adult patients with non-DIPG grade 4 gliomas: a contemporary pooled institutional experience. J Neurooncol. 2023 Jul; 163(3):717-726. PMID: 37440097.
      Citations:    Fields:    Translation:Humans
    18. Mash LE, Kahalley LS, Raghubar KP, Goodrich-Hunsaker NJ, Abildskov TJ, De Leon LA, MacLeod M, Stancel H, Parsons K, Biekman B, Desai NK, Grosshans DR, Paulino AC, Chu ZD, Whitehead WE, Okcu MF, Chintagumpala M, Wilde EA. Cognitive Sparing in Proton versus Photon Radiotherapy for Pediatric Brain Tumor Is Associated with White Matter Integrity: An Exploratory Study. Cancers (Basel). 2023 Mar 19; 15(6). PMID: 36980730; PMCID: PMC10047305.
      Citations:    
    19. Cao W, Li Y, Zhang X, Poenisch F, Yepes P, Sahoo N, Grosshans D, McGovern S, Gunn GB, Frank SJ, Zhu XR. Intensity modulated proton arc therapy via geometry-based energy selection for ependymoma. J Appl Clin Med Phys. 2023 Jul; 24(7):e13954. PMID: 36913484; PMCID: PMC10338743.
      Citations: 2     Fields:    Translation:Humans
    20. Mankad K, Packer R, Cavalheiro S, Bison B, M?ller HL, Bartels U, Hoffman LM, Jaimes C, Mirsky DM, Tamrazi B, Tinkle CL, Kline C, Ramasubramanian A, Malbari F, Mangum R, Lindsay H, Horne V, Daniels DJ, Keole S, Grosshans DR, Young Poussaint T, Hankinson TC, Warren KE, Chintagumpala M. Response assessment in pediatric craniopharyngioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) Working Group. Neuro Oncol. 2023 02 14; 25(2):224-233. PMID: 36124689; PMCID: PMC9925711.
      Citations:    
    21. Brown PD, Mahajan A, McGovern SL, Luo D, Johnson J, Nguyen K, Li J, McAleer MF, Yeboa D, Grosshans DR, Ghia AJ, Chung C, Bishop AJ, Song J, Thall PF. A Prospective Study of Conventionally Fractionated Dose Constraints for Reirradiation of Primary Brain Tumors in Adults. Pract Radiat Oncol. 2023 May-Jun; 13(3):231-238. PMID: 36596356.
      Citations:    Fields:    Translation:Humans
    22. Mash LE, Kahalley LS, Okcu MF, Grosshans DR, Paulino AC, Stancel H, De Leon L, Wilde E, Desai N, Chu ZD, Whitehead WE, Chintagumpala M, Raghubar KP, Mash LE, Kahalley LS, Okcu MF, Grosshans DR, Paulino AC, Stancel H, De Leon L, Wilde E, Desai N, Chu ZD, Whitehead WE, Chintagumpala M, Raghubar KP. Superior verbal learning and memory in pediatric brain tumor survivors treated with proton versus photon radiotherapy. Neuropsychology. 2023 Feb; 37(2):204-217. PMID: 36480379; PMCID: PMC10544942.
      Citations:    Fields:    Translation:Humans
    23. Kirkman MA, Day J, Gehring K, Zienius K, Grosshans D, Taphoorn M, Li J, Brown PD. Interventions for preventing and ameliorating cognitive deficits in adults treated with cranial irradiation. Cochrane Database Syst Rev. 2022 11 25; 11:CD011335. PMID: 36427235; PMCID: PMC9697842.
      Citations:    Fields:    Translation:Humans
    24. Chevli N, Grosshans DR, McAleer MF, Foster JH, Harrison D, McGovern SL, Paulino AC. Renal function in abdominal neuroblastoma patients undergoing proton radiotherapy. Pediatr Blood Cancer. 2023 01; 70(1):e29981. PMID: 36129239.
      Citations:    
    25. Upadhyay R, Liao K, Grosshans DR, McGovern SL, Frances McAleer M, Zaky W, Chintagumpala MM, Mahajan A, Nana Yeboa D, Paulino AC. Quantifying the risk and dosimetric variables of symptomatic brainstem injury after proton beam radiation in pediatric brain tumors. Neuro Oncol. 2022 09 01; 24(9):1571-1581. PMID: 35157767; PMCID: PMC9435496.
      Citations:    Fields:    
    26. Mallick S, V R A, Giridhar P, Upadhyay R, Kim BK, Sharma A, Elghazawy H, Elumalai T, Solipuram V, Hsieh CE, Hentz C, Solanki AA, Li J, Chan DP, Ness E, Venkatesulu BP, Grosshans DR. A Systematic Review and Meta-analysis of the Impact of Radiation-Related Lymphopenia on Outcomes in High-Grade Gliomas. South Asian J Cancer. 2022 Oct; 11(4):361-369. PMID: 36756098; PMCID: PMC9902102.
      Citations:    
    27. Bokhari RS, Beheshti A, Blutt SE, Bowles DE, Brenner D, Britton R, Bronk L, Cao X, Chatterjee A, Clay DE, Courtney C, Fox DT, Gaber MW, Gerecht S, Grabham P, Grosshans D, Guan F, Jezuit EA, Kirsch DG, Liu Z, Maletic-Savatic M, Miller KM, Montague RA, Nagpal P, Osenberg S, Parkitny L, Pierce NA, Porada C, Rosenberg SM, Sargunas P, Sharma S, Spangler J, Tavakol DN, Thomas D, Vunjak-Novakovic G, Wang C, Whitcomb L, Young DW, Donoviel D. Looking on the horizon; potential and unique approaches to developing radiation countermeasures for deep space travel. Life Sci Space Res (Amst). 2022 Nov; 35:105-112. PMID: 36336356.
      Citations:    Fields:    Translation:HumansAnimalsPHPublic Health
    28. Bronk JK, Amer A, Khose S, Flint D, Adair A, Yepes P, Grosshans D, Johnson J, Chung C. Brain Radiation Necrosis Outside the Target Volume After Proton Radiation Therapy: Analyses of Multiparametric Imaging and Proton Biologic Effectiveness. Adv Radiat Oncol. 2022 Nov-Dec; 7(6):101044. PMID: 36420203; PMCID: PMC9677210.
      Citations:    
    29. Mairani A, Mein S, Blakely E, Ferrari A, Fuchs H, Georg D, Grosshans DR, Guan F, Haberer T, Harrabi S, Inaniwa T, Karger CP, Mohan R, Paganetti H, Tessonnier T, Titt U, Debus J, Durante M, Horst F, Parodi K, Sala P, Schuy C, Weber U. Roadmap: helium ion therapy. Phys Med Biol. 2022 08 05; 67(15). PMID: 35395649.
      Citations:    Fields:    
    30. Bishop AJ, Amini B, Lin H, Raza SM, Patel S, Grosshans DR, Ghia A, Farooqi A, Guadagnolo BA, Mitra D, Akdemir KC, Lazar AJ, Wang WL, Alvarez-Breckenridge C, Bird J, Rhines LD, Somaiah N, Conley AP. Immune Checkpoint Inhibitors Have Clinical Activity in Patients With Recurrent Chordoma. J Immunother. 2022 10 01; 45(8):374-378. PMID: 35943386; PMCID: PMC9452485.
      Citations:    
    31. McNerlin C, Guan F, Bronk L, Lei K, Grosshans D, Young DW, Gaber MW, Maletic-Savatic M. Targeting hippocampal neurogenesis to protect astronauts' cognition and mood from decline due to space radiation effects. Life Sci Space Res (Amst). 2022 Nov; 35:170-179. PMID: 36336363.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    32. McCurdy MD, Raghubar KP, Christopher K, Okcu MF, Wilde E, Desai N, Chu ZD, Gragert M, Stancel H, Warren EH, Whitehead WE, Grosshans D, Paulino AC, Chintagumpala M, Kahalley LS. Predicting neurocognitive function in pediatric brain tumor early survivorship: The neurological predictor scale and the incremental validity of tumor size. Pediatr Blood Cancer. 2022 09; 69(9):e29803. PMID: 35709014; PMCID: PMC10265925.
      Citations:    Fields:    Translation:Humans
    33. De B, Florez MA, Ludmir EB, Maor MH, McGovern SL, McAleer MF, Grosshans DR, Chang EL, Mahajan A, Paulino AC. Late Effects of Craniospinal Irradiation Using Electron Spinal Fields for Pediatric Patients With Cancer. Int J Radiat Oncol Biol Phys. 2023 01 01; 115(1):164-173. PMID: 35716848.
      Citations:    Fields:    
    34. Gandy K, Chambers T, Raghubar KP, Fatih Okcu M, Chintagumpala M, Taylor O, Mahajan A, Kahalley LS, Chan W, Grosshans DR, Brown AL, Douglas Ris M. A Prospective Evaluation of Fatigue in Pediatric Brain Tumor Patients Treated With Radiation Therapy. J Pediatr Hematol Oncol Nurs. 2022 Nov-Dec; 39(6):358-365. PMID: 36285825.
      Citations:    Fields:    Translation:Humans
    35. Warren EAH, Raghubar KP, Cirino PT, Child AE, Lupo PJ, Grosshans DR, Paulino AC, Okcu MF, Minard CG, Ris MD, Mahajan A, Viana A, Chintagumpala M, Kahalley LS. Cognitive predictors of social adjustment in pediatric brain tumor survivors treated with photon versus proton radiation therapy. Pediatr Blood Cancer. 2022 06; 69(6):e29645. PMID: 35285129; PMCID: PMC9208675.
      Citations:    Fields:    Translation:Humans
    36. Tang TT, Zawaski JA, Kesler S, Beamish CA, Inoue T, Perez EC, Bronk L, Poenisch F, Briere TM, Sabek OM, Grosshans DR, Waleed Gaber M. Cognitive and Imaging Differences After Proton and Photon Whole Brain Irradiation in a Preclinical Model. Int J Radiat Oncol Biol Phys. 2022 02 01; 112(2):554-564. PMID: 34509550; PMCID: PMC8748279.
      Citations:    Fields:    Translation:Animals
    37. Brown PD, Chung C, Liu DD, McAvoy S, Grosshans D, Al Feghali K, Mahajan A, Li J, McGovern SL, McAleer MF, Ghia AJ, Sulman EP, Penas-Prado M, de Groot JF, Heimberger AB, Wang J, Armstrong TS, Gilbert MR, Guha-Thakurta N, Wefel JS. A prospective phase II randomized trial of proton radiotherapy vs intensity-modulated radiotherapy for patients with newly diagnosed glioblastoma. Neuro Oncol. 2021 08 02; 23(8):1337-1347. PMID: 33647972; PMCID: PMC8328012.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    38. Paulino AC, Ludmir EB, Grosshans DR, Su JM, McGovern SL, Okcu MF, McAleer MF, Baxter PA, Mahajan A, Chintagumpala MM. Overall survival and secondary malignant neoplasms in children receiving passively scattered proton or photon craniospinal irradiation for medulloblastoma. Cancer. 2021 Oct 15; 127(20):3865-3871. PMID: 34254296.
      Citations: 1     Fields:    Translation:Humans
    39. Spiotto MT, McGovern SL, Gunn GB, Grosshans D, McAleer MF, Frank SJ, Paulino AC. Proton Radiotherapy to Reduce Late Complications in Childhood Head and Neck Cancers. Int J Part Ther. 2021; 8(1):155-167. PMID: 34285943; PMCID: PMC8270100.
      Citations:    
    40. Child AE, Warren EA, Grosshans DR, Paulino AC, Okcu MF, Ris MD, Mahajan A, Orobio J, Cirino PT, Minard CG, Viana AG, Bick J, Woods SP, Chintagumpala M, Kahalley LS. Long-term cognitive and academic outcomes among pediatric brain tumor survivors treated with proton versus photon radiotherapy. Pediatr Blood Cancer. 2021 09; 68(9):e29125. PMID: 34114294; PMCID: PMC8316321.
      Citations: 2     Fields:    Translation:Humans
    41. Skaarup M, Lundemann MJ, Darkner S, Marner L, Mirkovic D, Grosshans D, Peeler C, Mohan R, Vogelius IR, Appelt A, J?rgensen M. A framework for voxel-based assessment of biological effect after proton radiotherapy in pediatric brain cancer patients using multi-modal imaging. Med Phys. 2021 Jul; 48(7):4110-4121. PMID: 34021597.
      Citations: 2     Fields:    Translation:HumansCells
    42. Al Feghali KA, Randall JW, Liu DD, Wefel JS, Brown PD, Grosshans DR, McAvoy SA, Farhat MA, Li J, McGovern SL, McAleer MF, Ghia AJ, Paulino AC, Sulman EP, Penas-Prado M, Wang J, de Groot J, Heimberger AB, Armstrong TS, Gilbert MR, Mahajan A, Guha-Thakurta N, Chung C. Phase II trial of proton therapy versus photon IMRT for GBM: secondary analysis comparison of progression-free survival between RANO versus clinical assessment. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab073. PMID: 34337411; PMCID: PMC8320688.
      Citations:    
    43. Milgrom SA, van Luijk P, Pino R, Kremer LC, Gidley PW, Grosshans DR, Laskar S, Okcu MF, Constine LS, Paulino AC, Ronckers CM. Salivary and Dental Complications in Childhood Cancer Survivors Treated With Radiation Therapy to the Head and Neck: A PENTEC Comprehensive Review. Int J Radiat Oncol Biol Phys. 2024 Jun 01; 119(2):467-481. PMID: 34074567.
      Citations: 2     Fields:    
    44. Heitzer AM, Kahalley LS, Minard CG, Stafford C, Grosshans DR, Okcu MF, Raghubar KP, Gragert M, McCurdy M, Warren EH, Gomez J, Ris MD, Paulino AC, Chintagumpala M. Treatment age and neurocognitive outcomes following proton beam radiotherapy for pediatric low- and intermediate-grade gliomas. Pediatr Blood Cancer. 2021 08; 68(8):e29096. PMID: 34019329; PMCID: PMC9040342.
      Citations:    Fields:    Translation:Humans
    45. Flint DB, Bright SJ, McFadden CH, Konishi T, Ohsawa D, Turner B, Lin SH, Grosshans DR, Chiu HS, Sumazin P, Shaitelman SF, Sawakuchi GO. Cell lines of the same anatomic site and histologic type show large variability in intrinsic radiosensitivity and relative biological effectiveness to protons and carbon ions. Med Phys. 2021 Jun; 48(6):3243-3261. PMID: 33837540.
      Citations:    Fields:    Translation:HumansCells
    46. Oyefiade A, Paltin I, De Luca CR, Hardy KK, Grosshans DR, Chintagumpala M, Mabbott DJ, Kahalley LS. Cognitive Risk in Survivors of Pediatric Brain Tumors. J Clin Oncol. 2021 06 01; 39(16):1718-1726. PMID: 33886348; PMCID: PMC8260914.
      Citations: 5     Fields:    Translation:Humans
    47. Hanania AN, Paulino AC, Ludmir EB, Shah VS, Su JM, McGovern SL, Baxter PA, McAleer MF, Grosshans DR, Okcu MF, Chintagumpala MM. Early radiotherapy preserves vision in sporadic optic pathway glioma. Cancer. 2021 07 01; 127(13):2358-2367. PMID: 33739455.
      Citations: 1     Fields:    Translation:Humans
    48. Nantavithya C, Paulino AC, Liao K, Woodhouse KD, McGovern SL, Grosshans DR, McAleer MF, Khatua S, Chintagumpala MM, Majd N, Zaky W, Yeboa DN. Observed-to-expected incidence ratios of second malignant neoplasms after radiation therapy for medulloblastoma: A Surveillance, Epidemiology, and End Results analysis. Cancer. 2021 07 01; 127(13):2368-2375. PMID: 33721338.
      Citations: 2     Fields:    Translation:Humans
    49. Bishop AJ, Livingston JA, Ning MS, Valdez ID, Wages CA, McAleer MF, Paulino AC, Grosshans DR, Woodhouse KD, Tao R, Roth ME, Gunn GB, McGovern SL. Young Adult Populations Face Yet Another Barrier to Care With Insurers: Limited Access to Proton Therapy. Int J Radiat Oncol Biol Phys. 2021 08 01; 110(5):1496-1504. PMID: 33677051; PMCID: PMC8286292.
      Citations: 1     Fields:    Translation:Humans
    50. Buszek SM, Ludmir EB, Grosshans DR, McAleer MF, McGovern SL, Harrison DJ, Okcu MF, Chintagumpala MM, Mahajan A, Paulino AC. Disease Control and Patterns of Failure After Proton Beam Therapy for Rhabdomyosarcoma. Int J Radiat Oncol Biol Phys. 2021 03 01; 109(3):718-725. PMID: 33516439.
      Citations:    Fields:    Translation:Humans
    51. Paganetti H, Beltran C, Both S, Dong L, Flanz J, Furutani K, Grassberger C, Grosshans DR, Knopf AC, Langendijk JA, Nystrom H, Raaymakers BW, Sawakuchi GO, Schippers M, Shaitelman SF, Teo BKK, Wohlfahrt P, Lomax T, Parodi K, Richter C, Unkelbach J. Roadmap: proton therapy physics and biology. Phys Med Biol. 2021 02 26; 66(5). PMID: 33227715; PMCID: PMC9275016.
      Citations: 8     Fields:    Translation:Humans
    52. Mohan R, Liu AY, Brown PD, Mahajan A, Dinh J, Chung C, McAvoy S, McAleer MF, Lin SH, Li J, Ghia AJ, Zhu C, Sulman EP, de Groot JF, Heimberger AB, McGovern SL, Grassberger C, Shih H, Ellsworth S, Grosshans DR. Proton therapy reduces the likelihood of high-grade radiation-induced lymphopenia in glioblastoma patients: phase II randomized study of protons vs photons. Neuro Oncol. 2021 02 25; 23(2):284-294. PMID: 32750703; PMCID: PMC7906048.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    53. Liu SM, Brooks ED, Rubin ML, MD Anderson Cancer Center Radiation Oncology Fellows Consortium, Grosshans DR, Frank SJ, McAleer MF, McGovern SL, Paulino AC, Woodhouse KD. Referral Patterns and Treatment Delays in Medulloblastoma: A Large Academic Proton Center Experience. Int J Part Ther. 2021; 7(3):1-10. PMID: 33604411; PMCID: PMC7886269.
      Citations: 1     
    54. Beamish CA, Zawaski JA, Inoue T, Sarkar P, Grosshans DR, Sabek OM, Gaber MW. NF-?B Blockade by NEMO Binding Domain Peptide Ameliorates Inflammation and Neurobehavioral Sequelae After Cranial Radiation Therapy in Juvenile Mice. Int J Radiat Oncol Biol Phys. 2021 04 01; 109(5):1508-1520. PMID: 33307152.
      Citations: 1     Fields:    Translation:Animals
    55. Bronk L, Guan F, Patel D, Ma D, Kroger B, Wang X, Tran K, Yiu J, Stephan C, Abdollahi A, Mohan R, Titt U, Grosshans DR, Debus J, J?kel O. Mapping the Relative Biological Effectiveness of Proton, Helium and Carbon Ions with High-Throughput Techniques. Cancers (Basel). 2020 Dec 05; 12(12). PMID: 33291477; PMCID: PMC7762185.
      Citations: 3     
    56. Abolfath R, Grosshans D, Mohan R. Oxygen depletion in FLASH ultra-high-dose-rate radiotherapy: A molecular dynamics simulation. Med Phys. 2020 Dec; 47(12):6551-6561. PMID: 33089504.
      Citations: 5     Fields:    Translation:Cells
    57. Ma D, Bronk L, Kerr M, Sobieski M, Chen M, Geng C, Yiu J, Wang X, Sahoo N, Cao W, Zhang X, Stephan C, Mohan R, Grosshans DR, Guan F. Author Correction: Exploring the advantages of intensity-modulated proton therapy: experimental validation of biological effects using two different beam intensity-modulation patterns. Sci Rep. 2020 Oct 30; 10(1):19101. PMID: 33127998; PMCID: PMC7603493.
      Citations: 2     Fields:    
    58. Lin TA, Ludmir EB, Liao KP, McAleer MF, Bishop AJ, Grosshans D, McGovern S, Woodhouse KD, Paulino AC, Yeboa DN. Relationship between treatment center case volume and survival for localized Ewing sarcoma: The role of radiotherapy timing. Pediatr Blood Cancer. 2020 11; 67(11):e28685. PMID: 32881378.
      Citations:    Fields:    Translation:Humans
    59. Bai X, Lim G, Grosshans D, Mohan R, Cao W. A biological effect-guided optimization approach using beam distal-edge avoidance for intensity-modulated proton therapy. Med Phys. 2020 Sep; 47(9):3816-3825. PMID: 32557747.
      Citations: 2     Fields:    Translation:HumansCells
    60. Vassiliev ON, Peterson CB, Grosshans DR, Mohan R. A simple model for calculating relative biological effectiveness of X-rays and gamma radiation in cell survival. Br J Radiol. 2020 Aug; 93(1112):20190949. PMID: 32464080; PMCID: PMC7446005.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    61. Noticewala SS, Ludmir EB, Bishop AJ, Chung C, Ghia AJ, Grosshans D, McGovern S, Paulino AC, Wang C, Woodhouse KD, Yeboa DN, Prabhu SS, Weathers SP, Das P, Koong AC, McAleer MF, Li J. Radiation for Glioblastoma in the Era of Coronavirus Disease 2019 (COVID-19): Patient Selection and Hypofractionation to Maximize Benefit and Minimize Risk. Adv Radiat Oncol. 2020 Jul-Aug; 5(4):743-745. PMID: 32775785; PMCID: PMC7251361.
      Citations: 6     
    62. Nantavithya C, Paulino AC, Liao K, McGovern SL, Grosshans DR, McAleer MF, Woodhouse KD, Khatua S, Chintagumpala MM, Majd NK, Yeboa DN. Development of second primary tumors and outcomes in medulloblastoma by treatment modality: A Surveillance, Epidemiology, and End Results analysis. Pediatr Blood Cancer. 2020 08; 67(8):e28373. PMID: 32453481.
      Citations: 1     Fields:    Translation:Humans
    63. Zhang D, Zhou W, Lam TT, Li Y, Duman JG, Dougherty PM, Grosshans DR. Cranial irradiation induces axon initial segment dysfunction and neuronal injury in the prefrontal cortex and impairs hippocampal coupling. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa058. PMID: 32642710; PMCID: PMC7260696.
      Citations: 1     
    64. Kahalley LS, Peterson R, Ris MD, Janzen L, Okcu MF, Grosshans DR, Ramaswamy V, Paulino AC, Hodgson D, Mahajan A, Tsang DS, Laperriere N, Whitehead WE, Dauser RC, Taylor MD, Bouffet E, Chintagumpala M, Mabbott D. Reply to S.A. Milgrom et al. J Clin Oncol. 2020 07 01; 38(19):2212-2213. PMID: 32374644; PMCID: PMC7325365.
      Citations: 1     Fields:    Translation:Humans
    65. Ma D, Bronk L, Kerr M, Sobieski M, Chen M, Geng C, Yiu J, Wang X, Sahoo N, Cao W, Zhang X, Stephan C, Mohan R, Grosshans DR, Guan F. Exploring the advantages of intensity-modulated proton therapy: experimental validation of biological effects using two different beam intensity-modulation patterns. Sci Rep. 2020 02 21; 10(1):3199. PMID: 32081928; PMCID: PMC7035246.
      Citations: 3     Fields:    Translation:HumansCells
    66. Brown PD, Gondi V, Pugh S, Tome WA, Wefel JS, Armstrong TS, Bovi JA, Robinson C, Konski A, Khuntia D, Grosshans D, Benzinger TLS, Bruner D, Gilbert MR, Kundapur V, Devisetty K, Shah S, Usuki K, Anderson BM, Stea B, Yoon H, Li J, Laack NN, Kruser TJ, Chmura SJ, Shi W, Deshmukh S, Mehta MP, Kachnic LA, for NRG Oncology, Roberge D. Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001. J Clin Oncol. 2020 04 01; 38(10):1019-1029. PMID: 32058845; PMCID: PMC7106984.
      Citations: 127     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    67. Abolfath R, Peeler C, Mirkovic D, Mohan R, Grosshans D. A DNA damage multiscale model for NTCP in proton and hadron therapy. Med Phys. 2020 Apr; 47(4):2005-2012. PMID: 31955444; PMCID: PMC10015418.
      Citations: 1     Fields:    Translation:Humans
    68. Raghubar KP, Rothhaar MC, Yeates KO, Mahone EM, Grosshans DR, Scheurer ME, Ris MD. Premorbid functioning as a predictor of outcome in pediatric brain tumor: An initial examination of the normalcy assumption. Pediatr Blood Cancer. 2020 04; 67(4):e28135. PMID: 31886612.
      Citations:    Fields:    Translation:Humans
    69. Kahalley LS, Peterson R, Ris MD, Janzen L, Okcu MF, Grosshans DR, Ramaswamy V, Paulino AC, Hodgson D, Mahajan A, Tsang DS, Laperriere N, Whitehead WE, Dauser RC, Taylor MD, Conklin HM, Chintagumpala M, Bouffet E, Mabbott D. Superior Intellectual Outcomes After Proton Radiotherapy Compared With Photon Radiotherapy for Pediatric Medulloblastoma. J Clin Oncol. 2020 02 10; 38(5):454-461. PMID: 31774710; PMCID: PMC7007288.
      Citations: 43     Fields:    Translation:HumansPHPublic Health
    70. Roth AK, Ris MD, Orobio J, Xue J, Mahajan A, Paulino AC, Grosshans D, Okcu MF, Chintagumpala M, Kahalley LS. Cognitive mediators of adaptive functioning outcomes in survivors of pediatric brain tumors treated with proton radiotherapy. Pediatr Blood Cancer. 2020 02; 67(2):e28064. PMID: 31736188; PMCID: PMC7433211.
      Citations: 2     Fields:    Translation:Humans
    71. Vassiliev ON, Peterson CB, Cao W, Grosshans DR, Mohan R. Systematic microdosimetric data for protons of therapeutic energies calculated with Geant4-DNA. Phys Med Biol. 2019 11 04; 64(21):215018. PMID: 31553958; PMCID: PMC7232815.
      Citations: 1     Fields:    
    72. Bright SJ, Flint DB, Chakraborty S, McFadden CH, Yoon DS, Bronk L, Titt U, Mohan R, Grosshans DR, Sumazin P, Shaitelman SF, Asaithamby A, Sawakuchi GO. Nonhomologous End Joining Is More Important Than Proton Linear Energy Transfer in Dictating Cell Death. Int J Radiat Oncol Biol Phys. 2019 12 01; 105(5):1119-1125. PMID: 31425731; PMCID: PMC6872929.
      Citations: 9     Fields:    Translation:HumansCells
    73. Buszek SM, Ludmir EB, Grosshans DR, McAleer MF, McGovern SL, Harrison DJ, Okcu MF, Chintagumpala MM, Mahajan A, Paulino AC. Patterns of failure and toxicity profile following proton beam therapy for pediatric bladder and prostate rhabdomyosarcoma. Pediatr Blood Cancer. 2019 11; 66(11):e27952. PMID: 31397065.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    74. Ludmir EB, Mahajan A, Ahern V, Ajithkumar T, Alapetite C, Bindra RS, Bishop AJ, Bolle S, Brown PD, Chalmers AJ, Chang EL, Chung C, Esiashvili N, Gandola L, Ghia AJ, Gondi V, Grosshans DR, Harrabi SB, Horan G, Indelicato DJ, Jalali R, Janssens GO, Laack NN, Laperriere N, Laprie A, Li J, Marcus KJ, McGovern SL, Merchant TE, Merrell KW, Parkes J, Paulino AC, Schwarz R, Shih HA, Sulman EP, Taylor RE, Thorp N, Timmermann B, Wheeler G, Wolden SL, Woodhouse KD, Yeboa DN, Yock TI, Kortmann RD, McAleer MF, Bernier-Chastagner V, Carrie C, Dieckmann K, Krause M, Padovani L, Souhami L. Assembling the brain trust: the multidisciplinary imperative in neuro-oncology. Nat Rev Clin Oncol. 2019 08; 16(8):521-522. PMID: 31150024.
      Citations: 1     Fields:    Translation:Humans
    75. Darne CD, Alsanea F, Robertson DG, Guan F, Pan T, Grosshans D, Beddar S. A proton imaging system using a volumetric liquid scintillator: a preliminary study. Biomed Phys Eng Express. 2019 Jul; 5(4). PMID: 32194988; PMCID: PMC7082085.
      Citations: 2     Fields:    
    76. Tang TT, Zawaski JA, Kesler SR, Beamish CA, Reddick WE, Glass JO, Carney DH, Sabek OM, Grosshans DR, Gaber MW. A comprehensive preclinical assessment of late-term imaging markers of radiation-induced brain injury. Neurooncol Adv. 2019 May-Dec; 1(1):vdz012. PMID: 31608330; PMCID: PMC6777502.
      Citations: 5     
    77. Kahalley LS, Douglas Ris M, Mahajan A, Fatih Okcu M, Chintagumpala M, Paulino AC, Whitehead WE, Minard CG, Stancel HH, Orobio J, Xue JJ, Warren EA, Grosshans DR. Prospective, longitudinal comparison of neurocognitive change in pediatric brain tumor patients treated with proton radiotherapy versus surgery only. Neuro Oncol. 2019 06 10; 21(6):809-818. PMID: 30753584; PMCID: PMC6558072.
      Citations: 13     Fields:    Translation:Humans
    78. Amsbaugh MJ, Mahajan A, Thall PF, McAleer MF, Paulino AC, Grosshans D, Khatua S, Ketonen L, Fontanilla H, McGovern SL. In Reply to Krishnatry and Manjali. Int J Radiat Oncol Biol Phys. 2019 06 01; 104(2):468-469. PMID: 31047634.
      Citations:    Fields:    Translation:Humans
    79. Raghubar KP, Orobio J, Ris MD, Heitzer AM, Roth A, Brown AL, Okcu MF, Chintagumpala M, Grosshans DR, Paulino AC, Mahajan A, Kahalley LS. Adaptive functioning in pediatric brain tumor survivors: An examination of ethnicity and socioeconomic status. Pediatr Blood Cancer. 2019 09; 66(9):e27800. PMID: 31134755; PMCID: PMC6730637.
      Citations: 5     Fields:    Translation:Humans
    80. Ludmir EB, Mahajan A, Paulino AC, Jones JY, Ketonen LM, Su JM, Grosshans DR, McAleer MF, McGovern SL, Lassen-Ramshad YA, Adesina AM, Dauser RC, Weinberg JS, Chintagumpala MM. Increased risk of pseudoprogression among pediatric low-grade glioma patients treated with proton versus photon radiotherapy. Neuro Oncol. 2019 05 06; 21(5):686-695. PMID: 30753704; PMCID: PMC6502497.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    81. Bagley AF, Grosshans DR, Philip NV, Foster J, McAleer MF, McGovern SL, Lassen-Ramshad Y, Mahajan A, Paulino AC. Efficacy of proton therapy in children with high-risk and locally recurrent neuroblastoma. Pediatr Blood Cancer. 2019 08; 66(8):e27786. PMID: 31050179; PMCID: PMC6588416.
      Citations: 5     Fields:    Translation:Humans
    82. Abolfath R, Helo Y, Bronk L, Carabe A, Grosshans D, Mohan R. Renormalization of radiobiological response functions by energy loss fluctuations and complexities in chromosome aberration induction: deactivation theory for proton therapy from cells to tumor control. Eur Phys J D At Mol Opt Phys. 2019 Mar; 73(3). PMID: 39148557; PMCID: PMC11325099.
      Citations: 4     
    83. Cao W, Khabazian A, Yepes P, Lim G, Poenisch F, Grosshans D, Mohan R. Reply to Comment on 'Linear energy transfer incorporated intensity modulated proton therapy optimization'. Phys Med Biol. 2019 02 27; 64(5):058002. PMID: 30811349.
      Citations: 1     Fields:    Translation:Cells
    84. Evans LT, DeMonte F, Grosshans DR, Ghia AJ, Habib A, Raza SM. Salvage Therapy for Local Progression following Definitive Therapy for Skull Base Chordomas: Is There a Role of Stereotactic Radiosurgery? J Neurol Surg B Skull Base. 2020 Feb; 81(1):97-106. PMID: 32021756; PMCID: PMC6997007.
      Citations:    
    85. Ludmir EB, Grosshans DR, McAleer MF, McGovern SL, Harrison DJ, Okcu MF, Chintagumpala MM, Mahajan A, Paulino AC. Patterns of failure following proton beam therapy for head and neck rhabdomyosarcoma. Radiother Oncol. 2019 05; 134:143-150. PMID: 31005208.
      Citations: 4     Fields:    Translation:Humans
    86. Paganetti H, Blakely E, Carabe-Fernandez A, Carlson DJ, Das IJ, Dong L, Grosshans D, Held KD, Mohan R, Moiseenko V, Niemierko A, Stewart RD, Willers H. Report of the AAPM TG-256 on the relative biological effectiveness of proton beams in radiation therapy. Med Phys. 2019 Mar; 46(3):e53-e78. PMID: 30661238; PMCID: PMC9559855.
      Citations: 44     Fields:    Translation:Humans
    87. Newpower M, Patel D, Bronk L, Guan F, Chaudhary P, McMahon SJ, Prise KM, Schettino G, Grosshans DR, Mohan R. Using the Proton Energy Spectrum and Microdosimetry to Model Proton Relative Biological Effectiveness. Int J Radiat Oncol Biol Phys. 2019 06 01; 104(2):316-324. PMID: 30731186; PMCID: PMC6499683.
      Citations: 6     Fields:    Translation:Cells
    88. Bai X, Lim G, Grosshans D, Mohan R, Cao W. Robust optimization to reduce the impact of biological effect variation from physical uncertainties in intensity-modulated proton therapy. Phys Med Biol. 2019 01 08; 64(2):025004. PMID: 30523932.
      Citations: 6     Fields:    Translation:HumansCells
    89. Amsbaugh MJ, Mahajan A, Thall PF, McAleer MF, Paulino AC, Grosshans D, Khatua S, Ketonen L, Fontanilla H, McGovern SL. A Phase 1/2 Trial of Reirradiation for Diffuse Intrinsic Pontine Glioma. Int J Radiat Oncol Biol Phys. 2019 05 01; 104(1):144-148. PMID: 30610915.
      Citations: 9     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    90. Paganetti H, Pompos A, Kry SF, Wu X, Grosshans DR, Durante M. Report of a National Cancer Institute special panel: Characterization of the physical parameters of particle beams for biological research. Med Phys. 2019 Feb; 46(2):e37-e52. PMID: 30506898.
      Citations: 5     Fields:    
    91. Yeboa DN, Yu JB, Liao E, Huse J, Penas-Prado M, Kann BH, Sulman E, Grosshans D, Contessa J. Differences in patterns of care and outcomes between grade II and grade III molecularly defined 1p19q co-deleted gliomas. Clin Transl Radiat Oncol. 2019 Feb; 15:46-52. PMID: 30656222; PMCID: PMC6329703.
      Citations: 3     
    92. Lin TA, Ludmir EB, Liao KP, McAleer MF, Grosshans DR, McGovern SL, Bishop AJ, Woodhouse KD, Paulino AC, Yeboa DN. Timing of Local Therapy Affects Survival in Ewing Sarcoma. Int J Radiat Oncol Biol Phys. 2019 05 01; 104(1):127-136. PMID: 30593906.
      Citations: 5     Fields:    Translation:Humans
    93. Guan F, Geng C, Carlson DJ, Ma DH, Bronk L, Gates D, Wang X, Kry SF, Grosshans D, Mohan R. A mechanistic relative biological effectiveness model-based biological dose optimization for charged particle radiobiology studies. Phys Med Biol. 2018 12 21; 64(1):015008. PMID: 30523805.
      Citations: 1     Fields:    Translation:Humans
    94. Buszek SM, Ikner S, Wiedemann L, Wang J, McAleer MF, Grosshans DR, Paulino AC, McGovern SL, Chung C. Safety and Feasibility of Magnetic Resonance Imaging Simulation for Radiation Treatment Planning in Pediatric Patients: A Single Institution Experience. Adv Radiat Oncol. 2019 Apr-Jun; 4(2):362-366. PMID: 31011682; PMCID: PMC6460291.
      Citations: 1     
    95. Ning MS, Gomez DR, Shah AK, Kim CR, Palmer MB, Thaker NG, Grosshans DR, Liao Z, Chapman BV, Brooks ED, Tang C, Rosenthal DI, Garden AS, Frank SJ, Gunn GB. The Insurance Approval Process for Proton Radiation Therapy: A Significant Barrier to Patient Care. Int J Radiat Oncol Biol Phys. 2019 07 15; 104(4):724-733. PMID: 30557675.
      Citations: 20     Fields:    Translation:Humans
    96. Yepes P, Adair A, Frank SJ, Grosshans DR, Liao Z, Liu A, Mirkovic D, Poenisch F, Titt U, Wang Q, Mohan R. Fixed- versus Variable-RBE Computations for Intensity Modulated Proton Therapy. Adv Radiat Oncol. 2019 Jan-Mar; 4(1):156-167. PMID: 30706024; PMCID: PMC6349601.
      Citations: 5     
    97. Stoker J, Vora S, Patel A, Grosshans D, Brown PD, Vern-Gross T, Bues M, Daniels T, Allred B, Uejo A, Kosiorek H, Bruso M, Keole S. Advantages of intensity modulated proton therapy during hippocampal avoidance whole brain radiation therapy. Phys Imaging Radiat Oncol. 2018 Oct; 8:28-32. PMID: 33458413; PMCID: PMC7807533.
      Citations: 4     
    98. Jaramillo S, Grosshans DR, Philip N, Varan A, McAleer MF, Mahajan A, McGovern SL, Aky?z C. Radiation for ETMR: Literature review and case series of patients treated with proton therapy. Clin Transl Radiat Oncol. 2019 Feb; 15:31-37. PMID: 30582019; PMCID: PMC6297264.
      Citations: 8     
    99. Ludmir EB, Grosshans DR, Woodhouse KD. Radiotherapy Advances in Pediatric Neuro-Oncology. Bioengineering (Basel). 2018 Nov 04; 5(4). PMID: 30400370; PMCID: PMC6315761.
      Citations: 7     
    100. Guan F, Geng C, Ma D, Bronk L, Kerr M, Li Y, Gates D, Kroger B, Sahoo N, Titt U, Grosshans D, Mohan R. RBE Model-Based Biological Dose Optimization for Proton Radiobiology Studies. Int J Part Ther. 2018; 5(1):160-171. PMID: 30338268; PMCID: PMC6191045.
      Citations: 8     
    101. Grosshans DR, Duman JG, Gaber MW, Sawakuchi G. Particle Radiation Induced Neurotoxicity in the Central Nervous System. Int J Part Ther. 2018; 5(1):74-83. PMID: 31773021; PMCID: PMC6871599.
      Citations: 3     
    102. Vatner RE, Niemierko A, Misra M, Weyman EA, Goebel CP, Ebb DH, Jones RM, Huang MS, Mahajan A, Grosshans DR, Paulino AC, Stanley T, MacDonald SM, Tarbell NJ, Yock TI. Endocrine Deficiency As a Function of Radiation Dose to the Hypothalamus and Pituitary in Pediatric and Young Adult Patients With Brain Tumors. J Clin Oncol. 2018 10 01; 36(28):2854-2862. PMID: 30118397; PMCID: PMC6161835.
      Citations: 25     Fields:    Translation:HumansPHPublic Health
    103. Zhang D, Zhou W, Lam TT, Weng C, Bronk L, Ma D, Wang Q, Duman JG, Dougherty PM, Grosshans DR. Radiation induces age-dependent deficits in cortical synaptic plasticity. Neuro Oncol. 2018 08 02; 20(9):1207-1214. PMID: 29660023; PMCID: PMC6107999.
      Citations: 9     Fields:    Translation:AnimalsCellsPHPublic Health
    104. Raza SM, Bell D, Freeman JL, Grosshans DR, Fuller GN, DeMonte F. Multimodality Management of Recurrent Skull Base Chordomas: Factors Impacting Tumor Control and Disease-Specific Survival. Oper Neurosurg (Hagerstown). 2018 08 01; 15(2):131-143. PMID: 29040778.
      Citations: 3     Fields:    Translation:Humans
    105. Grosshans DR, Brown PD. Chemotherapy Plus Proton or Photon Radiation on a Trial. Int J Radiat Oncol Biol Phys. 2018 07 01; 101(3):518-519. PMID: 29893270.
      Citations:    Fields:    Translation:Humans
    106. Willers H, Allen A, Grosshans D, McMahon SJ, Wiese C, Vikram B, von Neubeck C. Toward A variable RBE for proton beam therapy. Radiother Oncol. 2018 07; 128(1):68-75. PMID: 29910006.
      Citations: 25     Fields:    Translation:HumansCells
    107. Raghubar KP, Lamba M, Cecil KM, Yeates KO, Mahone EM, Limke C, Grosshans D, Beckwith TJ, Ris MD. Dose-volume metrics and their relation to memory performance in pediatric brain tumor patients: A preliminary study. Pediatr Blood Cancer. 2018 09; 65(9):e27245. PMID: 29856521; PMCID: PMC7388179.
      Citations: 5     Fields:    Translation:Humans
    108. Haas-Kogan D, Indelicato D, Paganetti H, Esiashvili N, Mahajan A, Yock T, Flampouri S, MacDonald S, Fouladi M, Stephen K, Kalapurakal J, Terezakis S, Kooy H, Grosshans D, Makrigiorgos M, Mishra K, Poussaint TY, Cohen K, Fitzgerald T, Gondi V, Liu A, Michalski J, Mirkovic D, Mohan R, Perkins S, Wong K, Vikram B, Buchsbaum J, Kun L. National Cancer Institute Workshop on Proton Therapy for Children: Considerations Regarding Brainstem Injury. Int J Radiat Oncol Biol Phys. 2018 05 01; 101(1):152-168. PMID: 29619963; PMCID: PMC5903576.
      Citations: 36     Fields:    Translation:HumansCellsPHPublic Health
    109. Wilke C, Grosshans D, Duman J, Brown P, Li J. Radiation-induced cognitive toxicity: pathophysiology and interventions to reduce toxicity in adults. Neuro Oncol. 2018 04 09; 20(5):597-607. PMID: 29045710; PMCID: PMC5892147.
      Citations: 14     Fields:    Translation:HumansPHPublic Health
    110. Duman JG, Dinh J, Zhou W, Cham H, Mavratsas VC, Mulherkar S, McGovern SL, Tolias KF, Grosshans DR, Pave?kovic M. Memantine prevents acute radiation-induced toxicities at hippocampal excitatory synapses. Neuro Oncol. 2018 04 09; 20(5):655-665. PMID: 29112734; PMCID: PMC5892158.
      Citations: 15     Fields:    Translation:AnimalsCellsPHPublic Health
    111. Vassiliev ON, Kry SF, Grosshans DR, Mohan R. Average stopping powers for electron and photon sources for radiobiological modeling and microdosimetric applications. Phys Med Biol. 2018 03 02; 63(5):055007. PMID: 29411712; PMCID: PMC5856245.
      Citations: 2     Fields:    Translation:Humans
    112. Taleei R, Guan F, Peeler C, Bronk L, Patel D, Mirkovic D, Grosshans DR, Mohan R, Titt U. Erratum: "Monte Carlo simulations of 3 He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness" [Med. Phys. 43 (2), page range 761-776(2016)]. Med Phys. 2018 Mar; 45(3):1301. PMID: 29527699.
      Citations:    Fields:    
    113. Guan F, Peeler C, Bronk L, Geng C, Taleei R, Randeniya S, Ge S, Mirkovic D, Grosshans D, Mohan R, Titt U. Erratum: "Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant4 Monte Carlo code" [Med. Phys. 42 (11), page range 6234-6247(2015)]. Med Phys. 2018 Mar; 45(3):1302. PMID: 29527697; PMCID: PMC6963003.
      Citations:    Fields:    
    114. Yepes P, Adair A, Grosshans D, Mirkovic D, Poenisch F, Titt U, Wang Q, Mohan R. Comparison of Monte Carlo and analytical dose computations for intensity modulated proton therapy. Phys Med Biol. 2018 02 09; 63(4):045003. PMID: 29339570; PMCID: PMC5906701.
      Citations: 16     Fields:    Translation:Humans
    115. Ludmir EB, Paulino AC, Grosshans DR, McAleer MF, McGovern SL, Huh WW, Okcu MF, Harrell LM, Mahajan A. Regional Nodal Control for Head and Neck Alveolar Rhabdomyosarcoma. Int J Radiat Oncol Biol Phys. 2018 05 01; 101(1):169-176. PMID: 29477293.
      Citations: 2     Fields:    Translation:Humans
    116. Paulino AC, Mahajan A, Ye R, Grosshans DR, Fatih Okcu M, Su J, McAleer MF, McGovern S, Mangona VA, Chintagumpala M. Ototoxicity and cochlear sparing in children with medulloblastoma: Proton vs. photon radiotherapy. Radiother Oncol. 2018 07; 128(1):128-132. PMID: 29373195.
      Citations: 9     Fields:    Translation:Humans
    117. Bronk JK, Guha-Thakurta N, Allen PK, Mahajan A, Grosshans DR, McGovern SL. Analysis of pseudoprogression after proton or photon therapy of 99 patients with low grade and anaplastic glioma. Clin Transl Radiat Oncol. 2018 Feb; 9:30-34. PMID: 29594248; PMCID: PMC5862685.
      Citations: 15     
    118. Mohan R, Held KD, Story MD, Grosshans D, Capala J. Proceedings of the National Cancer Institute Workshop on Charged Particle Radiobiology. Int J Radiat Oncol Biol Phys. 2018 03 15; 100(4):816-831. PMID: 29485053.
      Citations: 5     Fields:    Translation:Humans
    119. Cao W, Khabazian A, Yepes PP, Lim G, Poenisch F, Grosshans DR, Mohan R. Linear energy transfer incorporated intensity modulated proton therapy optimization. Phys Med Biol. 2017 12 19; 63(1):015013. PMID: 29131808; PMCID: PMC5815879.
      Citations: 15     Fields:    Translation:HumansCells
    120. Wang X, Li Y, Zhang X, Li H, Miyazaki K, Fujimoto R, Akiyama H, Gillin MT, Poenisch F, Sahoo N, Grosshans D, Gunn B, Frank SJ, Wang P, Lang J, Hou Q, Zhu XR. Synchrotron-Based Pencil Beam Scanning Nozzle with an Integrated Mini-Ridge Filter: A Dosimetric Study to Optimize Treatment Delivery. Cancers (Basel). 2017 Dec 13; 9(12). PMID: 29236051; PMCID: PMC5742818.
      Citations:    
    121. Patel D, Bronk L, Guan F, Peeler CR, Brons S, Dokic I, Abdollahi A, Grosshans D, Mohan R, Titt U, Rittm?ller C, J?kel O. Optimization of Monte Carlo particle transport parameters and validation of a novel high throughput experimental setup to measure the biological effects of particle beams. Med Phys. 2017 Nov; 44(11):6061-6073. PMID: 28880368.
      Citations: 6     Fields:    Translation:HumansCells
    122. Vassiliev ON, Grosshans DR, Mohan R. A new formalism for modelling parameters a and ? of the linear-quadratic model of cell survival for hadron therapy. Phys Med Biol. 2017 Oct 03; 62(20):8041-8059. PMID: 28832343; PMCID: PMC5737022.
      Citations: 4     Fields:    Translation:HumansCells
    123. Chun SG, Solberg TD, Grosshans DR, Nguyen QN, Simone CB, Mohan R, Liao Z, Hahn SM, Herman JM, Frank SJ. The Potential of Heavy-Ion Therapy to Improve Outcomes for Locally Advanced Non-Small Cell Lung Cancer. Front Oncol. 2017; 7:201. PMID: 28929085; PMCID: PMC5591826.
      Citations: 3     
    124. Raza SM, Gidley PW, Meis JM, Grosshans DR, Bell D, DeMonte F. Multimodality Treatment of Skull Base Chondrosarcomas: The Role of Histology Specific Treatment Protocols. Neurosurgery. 2017 Sep 01; 81(3):520-530. PMID: 28368506.
      Citations: 8     Fields:    Translation:Humans
    125. Mohan R, Peeler CR, Guan F, Bronk L, Cao W, Grosshans DR. Radiobiological issues in proton therapy. Acta Oncol. 2017 Nov; 56(11):1367-1373. PMID: 28826292; PMCID: PMC5842809.
      Citations: 17     Fields:    Translation:Humans
    126. Abolfath R, Peeler CR, Newpower M, Bronk L, Grosshans D, Mohan R. A model for relative biological effectiveness of therapeutic proton beams based on a global fit of cell survival data. Sci Rep. 2017 08 21; 7(1):8340. PMID: 28827691; PMCID: PMC5567137.
      Citations: 5     Fields:    Translation:HumansCells
    127. Antonini TN, Ris MD, Grosshans DR, Mahajan A, Okcu MF, Chintagumpala M, Paulino A, Child AE, Orobio J, Stancel HH, Kahalley LS. Attention, processing speed, and executive functioning in pediatric brain tumor survivors treated with proton beam radiation therapy. Radiother Oncol. 2017 07; 124(1):89-97. PMID: 28655455; PMCID: PMC5546418.
      Citations: 21     Fields:    Translation:HumansPHPublic Health
    128. Grosshans DR, Mohan R, Gondi V, Shih HA, Mahajan A, Brown PD. The role of image-guided intensity modulated proton therapy in glioma. Neuro Oncol. 2017 04 01; 19(suppl_2):ii30-ii37. PMID: 28380636; PMCID: PMC5463497.
      Citations: 5     Fields:    Translation:Humans
    129. Hou P, Zhu KH, Park PC, Li H, Mahajan A, Grosshans DR. Proton Therapy for Juvenile Pilocytic Astrocytoma: Quantifying Treatment Responses by Magnetic Resonance Diffusion Tensor Imaging. Int J Part Ther. 2017; 3(3):414-420. PMID: 31772991; PMCID: PMC6871604.
      Citations: 2     
    130. Liao L, Lim GJ, Li Y, Yu J, Sahoo N, Li H, Gillin M, Zhu XR, Mahajan A, Frank SJ, Grosshans DR, Nguyen QN, Gomez D, Zhang X. Robust Optimization for Intensity Modulated Proton Therapy Plans with Multi-Isocenter Large Fields. Int J Part Ther. 2016; 3(2):305-311. PMID: 31772982; PMCID: PMC6871617.
      Citations: 1     
    131. Mohan R, Grosshans D. Proton therapy - Present and future. Adv Drug Deliv Rev. 2017 01 15; 109:26-44. PMID: 27919760; PMCID: PMC5303653.
      Citations: 83     Fields:    Translation:Humans
    132. Peeler CR, Mirkovic D, Titt U, Gunther JR, Mahajan A, Mohan R, Grosshans DR, Blanchard P. Clinical evidence of variable proton biological effectiveness in pediatric patients treated for ependymoma. Radiother Oncol. 2016 12; 121(3):395-401. PMID: 27863964; PMCID: PMC5450501.
      Citations: 56     Fields:    Translation:HumansCells
    133. Wilkinson B, Morgan H, Gondi V, Larson GL, Hartsell WF, Laramore GE, Halasz LM, Vargas C, Keole SR, Grosshans DR, Shih HA, Mehta MP. Low Levels of Acute Toxicity Associated With Proton Therapy for Low-Grade Glioma: A Proton Collaborative Group Study. Int J Radiat Oncol Biol Phys. 2016 Oct 01; 96(2S):E135. PMID: 27673869.
      Citations:    
    134. Greenfield BJ, Jaramillo S, Abboud M, Mahajan A, Paulino AC, McGovern S, McAleer MF, Chintagumpala M, Okcu MF, Khatua S, Su J, Grosshans DR. Outcomes for pediatric patients with central nervous system germ cell tumors treated with proton therapy. Clin Transl Radiat Oncol. 2016 Dec; 1:9-14. PMID: 29657988; PMCID: PMC5893478.
      Citations: 3     
    135. Wang X, Poenisch F, Sahoo N, Zhu RX, Lii M, Gillin MT, Li J, Grosshans D. Spot scanning proton therapy minimizes neutron dose in the setting of radiation therapy administered during pregnancy. J Appl Clin Med Phys. 2016 09 08; 17(5):366-376. PMID: 27685136; PMCID: PMC5874122.
      Citations: 3     Fields:    Translation:Humans
    136. Jiang S, Wang J, Li H, Liao L, Li Y, Wang X, Yang Y, Zhu RX, Sahoo N, Gillin MT, Hojo Y, Sun J, Chang JY, Liao Z, Grosshans D, Frank SJ, Zhang X. Novel Hybrid Scattering- and Scanning-Beam Proton Therapy Approach. Int J Part Ther. 2016; 3(1):37-50. PMID: 31772974; PMCID: PMC6871576.
      Citations:    
    137. Tucker SL, Liu A, Gomez D, Tang LL, Allen P, Yang J, Liao Z, Grosshans D. Impact of heart and lung dose on early survival in patients with non-small cell lung cancer treated with chemoradiation. Radiother Oncol. 2016 06; 119(3):495-500. PMID: 27189523.
      Citations: 37     Fields:    Translation:Humans
    138. Agarwal A, Thaker NG, Tawk B, Allen PK, Grosshans DR, Herzog CE, Gombos DS, Mahajan A. The Evolution of Radiation Therapy for Retinoblastoma: The MD Anderson Cancer Center Experience. Int J Part Ther. 2016 Mar; 2(4):490-498. PMID: 31772961; PMCID: PMC6871642.
      Citations:    
    139. Taleei R, Guan F, Peeler C, Bronk L, Patel D, Mirkovic D, Grosshans DR, Mohan R, Titt U. Monte Carlo simulations of ?He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness. Med Phys. 2016 Feb; 43(2):761-76. PMID: 26843239.
      Citations: 3     Fields:    
    140. Grosshans DR. Proton therapy for paediatric medulloblastoma. Lancet Oncol. 2016 Mar; 17(3):258-259. PMID: 26830376; PMCID: PMC6207934.
      Citations: 2     Fields:    Translation:Humans
    141. Kahalley LS, Ris MD, Grosshans DR, Okcu MF, Paulino AC, Chintagumpala M, Moore BD, Guffey D, Minard CG, Stancel HH, Mahajan A. Comparing Intelligence Quotient Change After Treatment With Proton Versus Photon Radiation Therapy for Pediatric Brain Tumors. J Clin Oncol. 2016 Apr 01; 34(10):1043-9. PMID: 26811522; PMCID: PMC4872015.
      Citations: 51     Fields:    Translation:Humans
    142. Owusu-Agyemang P, Popovich SM, Zavala AM, Grosshans DR, Van Meter A, Williams UU, Holmes AA, Arunkumar R, Rebello E, McAleer MF, Porche V, Mahajan A. A multi-institutional pilot survey of anesthesia practices during proton radiation therapy. Pract Radiat Oncol. 2016 May-Jun; 6(3):155-159. PMID: 26725965.
      Citations: 3     Fields:    Translation:Humans
    143. Guan F, Peeler C, Bronk L, Geng C, Taleei R, Randeniya S, Ge S, Mirkovic D, Grosshans D, Mohan R, Titt U. Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant4 Monte Carlo code. Med Phys. 2015 Nov; 42(11):6234-47. PMID: 26520716; PMCID: PMC4600086.
      Citations: 28     Fields:    Translation:HumansCells
    144. Munck af Rosenschold P, Engelholm SA, Brodin PN, Grosshans DR, Zhu RX, Palmer M, Crawford CN, Mahajan A, J?rgensen M. A Retrospective Evaluation of the Benefit of Referring Pediatric Cancer Patients to an External Proton Therapy Center. Pediatr Blood Cancer. 2016 Feb; 63(2):262-9. PMID: 26397177.
      Citations: 4     Fields:    Translation:Humans
    145. Grant SR, Grosshans DR, Bilton SD, Garcia JA, Amin M, Chambers MS, McGovern SL, McAleer MF, Morrison WH, Huh WW, Kupferman ME, Mahajan A. Proton versus conventional radiotherapy for pediatric salivary gland tumors: Acute toxicity and dosimetric characteristics. Radiother Oncol. 2015 Aug; 116(2):309-15. PMID: 26232128; PMCID: PMC4783170.
      Citations: 10     Fields:    Translation:Humans
    146. Guan F, Bronk L, Titt U, Lin SH, Mirkovic D, Kerr MD, Zhu XR, Dinh J, Sobieski M, Stephan C, Peeler CR, Taleei R, Mohan R, Grosshans DR. Spatial mapping of the biologic effectiveness of scanned particle beams: towards biologically optimized particle therapy. Sci Rep. 2015 May 18; 5:9850. PMID: 25984967; PMCID: PMC4650781.
      Citations: 43     Fields:    Translation:HumansCells
    147. Mitra HS, Somerson JS, Rhines LD, Mahajan A, Brown PD, Grosshans DR, Holliday EB. Postoperative proton therapy for chordomas and chondrosarcomas of the spine: adjuvant versus salvage radiation therapy. Spine (Phila Pa 1976). 2015 Apr 15; 40(8):544-9. PMID: 25627289.
      Citations: 18     Fields:    Translation:Humans
    148. Day J, Zienius K, Gehring K, Grosshans D, Taphoorn M, Grant R, Li J, Brown PD. Interventions for preventing and ameliorating cognitive deficits in adults treated with cranial irradiation. Cochrane Database Syst Rev. 2014 Dec 18; (12):CD011335. PMID: 25519950; PMCID: PMC6457828.
      Citations: 17     Fields:    Translation:Humans
    149. McGovern SL, Grosshans D, Mahajan A. Embryonal brain tumors. Cancer J. 2014 Nov-Dec; 20(6):397-402. PMID: 25415685.
      Citations: 5     Fields:    Translation:Humans
    150. Ladra MM, Szymonifka JD, Mahajan A, Friedmann AM, Yong Yeap B, Goebel CP, MacDonald SM, Grosshans DR, Rodriguez-Galindo C, Marcus KJ, Tarbell NJ, Yock TI. Preliminary results of a phase II trial of proton radiotherapy for pediatric rhabdomyosarcoma. J Clin Oncol. 2014 Nov 20; 32(33):3762-70. PMID: 25332253; PMCID: PMC4226806.
      Citations: 33     Fields:    Translation:HumansCTClinical Trials
    151. Ladra MM, Edgington SK, Mahajan A, Grosshans D, Szymonifka J, Khan F, Moteabbed M, Friedmann AM, MacDonald SM, Tarbell NJ, Yock TI. A dosimetric comparison of proton and intensity modulated radiation therapy in pediatric rhabdomyosarcoma patients enrolled on a prospective phase II proton study. Radiother Oncol. 2014 Oct; 113(1):77-83. PMID: 25443861; PMCID: PMC4298831.
      Citations: 25     Fields:    Translation:HumansCTClinical Trials
    152. McGovern SL, Okcu MF, Munsell MF, Kumbalasseriyil N, Grosshans DR, McAleer MF, Chintagumpala M, Khatua S, Mahajan A. Outcomes and acute toxicities of proton therapy for pediatric atypical teratoid/rhabdoid tumor of the central nervous system. Int J Radiat Oncol Biol Phys. 2014 Dec 01; 90(5):1143-52. PMID: 25311260; PMCID: PMC4327980.
      Citations: 25     Fields:    Translation:HumansPHPublic Health
    153. Yusuf SW, Munsell MF, Welsh JW, Liao Z, Lin SH, Pan HY, Chang JY, Komaki R, Cox JD, McAleer MF, Grosshans DR, Gomez DR. Prospective exploratory analysis of cardiac biomarkers and electrocardiogram abnormalities in patients receiving thoracic radiation therapy with high-dose heart exposure. J Thorac Oncol. 2014 Oct; 9(10):1554-60. PMID: 25521400; PMCID: PMC4273574.
      Citations: 26     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    154. Grosshans DR, Zhu XR, Melancon A, Allen PK, Poenisch F, Palmer M, McAleer MF, McGovern SL, Gillin M, DeMonte F, Chang EL, Brown PD, Mahajan A. Spot scanning proton therapy for malignancies of the base of skull: treatment planning, acute toxicities, and preliminary clinical outcomes. Int J Radiat Oncol Biol Phys. 2014 Nov 01; 90(3):540-6. PMID: 25304948.
      Citations: 13     Fields:    Translation:HumansPHPublic Health
    155. Zhu XR, Poenisch F, Li H, Zhang X, Sahoo N, Wu RY, Li X, Lee AK, Chang EL, Choi S, Pugh T, Frank SJ, Gillin MT, Mahajan A, Grosshans DR. A single-field integrated boost treatment planning technique for spot scanning proton therapy. Radiat Oncol. 2014 Sep 11; 9:202. PMID: 25212571; PMCID: PMC4262206.
      Citations: 11     Fields:    Translation:Humans
    156. Stoker JB, Grant J, Zhu XR, Pidikiti R, Mahajan A, Grosshans DR. Intensity modulated proton therapy for craniospinal irradiation: organ-at-risk exposure and a low-gradient junctioning technique. Int J Radiat Oncol Biol Phys. 2014 Nov 01; 90(3):637-44. PMID: 25194667.
      Citations: 8     Fields:    Translation:Humans
    157. LeRoux LG, Bredow S, Grosshans D, Schellingerhout D. Molecular imaging detects impairment in the retrograde axonal transport mechanism after radiation-induced spinal cord injury. Mol Imaging Biol. 2014 Aug; 16(4):504-10. PMID: 24395625; PMCID: PMC4085152.
      Citations: 4     Fields:    Translation:AnimalsPHPublic Health
    158. Bishop AJ, Greenfield B, Mahajan A, Paulino AC, Okcu MF, Allen PK, Chintagumpala M, Kahalley LS, McAleer MF, McGovern SL, Whitehead WE, Grosshans DR. Proton beam therapy versus conformal photon radiation therapy for childhood craniopharyngioma: multi-institutional analysis of outcomes, cyst dynamics, and toxicity. Int J Radiat Oncol Biol Phys. 2014 Oct 01; 90(2):354-61. PMID: 25052561; PMCID: PMC4194252.
      Citations: 34     Fields:    Translation:Humans
    159. Shao Y, Sun X, Lou K, Zhu XR, Mirkovic D, Poenisch F, Grosshans D. In-beam PET imaging for on-line adaptive proton therapy: an initial phantom study. Phys Med Biol. 2014 Jul 07; 59(13):3373-88. PMID: 24874943.
      Citations: 9     Fields:    
    160. Owusu-Agyemang P, Grosshans D, Arunkumar R, Rebello E, Popovich S, Zavala A, Williams C, Ruiz J, Hernandez M, Mahajan A, Porche V. Non-invasive anesthesia for children undergoing proton radiation therapy. Radiother Oncol. 2014 Apr; 111(1):30-4. PMID: 24560754.
      Citations: 5     Fields:    Translation:Humans
    161. Liu W, Mohan R, Park P, Liu Z, Li H, Li X, Li Y, Wu R, Sahoo N, Dong L, Zhu XR, Grosshans DR. Dosimetric benefits of robust treatment planning for intensity modulated proton therapy for base-of-skull cancers. Pract Radiat Oncol. 2014 Nov-Dec; 4(6):384-91. PMID: 25407859; PMCID: PMC4238033.
      Citations: 27     Fields:    Translation:Humans
    162. Dinh J, Stoker J, Georges RH, Sahoo N, Zhu XR, Rath S, Mahajan A, Grosshans DR. Comparison of proton therapy techniques for treatment of the whole brain as a component of craniospinal radiation. Radiat Oncol. 2013 Dec 17; 8:289. PMID: 24344645; PMCID: PMC3880207.
      Citations: 4     Fields:    Translation:Humans
    163. Barney CL, Brown AP, Grosshans DR, McAleer MF, de Groot JF, Puduvalli V, Tucker SL, Crawford CN, Gilbert MR, Brown PD, Mahajan A. Technique, outcomes, and acute toxicities in adults treated with proton beam craniospinal irradiation. Neuro Oncol. 2014 Jan; 16(2):303-9. PMID: 24311638; PMCID: PMC3895378.
      Citations: 13     Fields:    Translation:Humans
    164. Tucker SL, Liao Z, Dinh J, Bian SX, Mohan R, Martel MK, Grosshans DR. Is there an impact of heart exposure on the incidence of radiation pneumonitis? Analysis of data from a large clinical cohort. Acta Oncol. 2014 May; 53(5):590-6. PMID: 23992110.
      Citations: 10     Fields:    Translation:Humans
    165. Brown AP, Barney CL, Grosshans DR, McAleer MF, de Groot JF, Puduvalli VK, Tucker SL, Crawford CN, Khan M, Khatua S, Gilbert MR, Brown PD, Mahajan A. Proton beam craniospinal irradiation reduces acute toxicity for adults with medulloblastoma. Int J Radiat Oncol Biol Phys. 2013 Jun 01; 86(2):277-84. PMID: 23433794; PMCID: PMC3954470.
      Citations: 52     Fields:    Translation:Humans
    166. Bian SX, McAleer MF, Vats TS, Mahajan A, Grosshans DR. Pilocytic astrocytoma with leptomeningeal dissemination. Childs Nerv Syst. 2013 Mar; 29(3):441-50. PMID: 23207974.
      Citations: 9     Fields:    Translation:Humans
    167. Sharp H, Grosshans D, Kadia T, Dabaja BS. Cutaneous graft-versus-host disease after proton-based craniospinal irradiation for recurrent Philadelphia-positive acute lymphoblastic leukaemia. BMJ Case Rep. 2012 Jul 11; 2012. PMID: 22787181; PMCID: PMC3417036.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    168. Wu PH, Coultrap S, Pinnix C, Davies KD, Tailor R, Ang KK, Browning MD, Grosshans DR. Radiation induces acute alterations in neuronal function. PLoS One. 2012; 7(5):e37677. PMID: 22662188; PMCID: PMC3360766.
      Citations: 33     Fields:    Translation:AnimalsCells
    169. Amsbaugh MJ, Zhu XR, Palmer M, Poenisch F, McAleer MF, Mahajan A, Grosshans DR. Spot scanning proton therapy for craniopharyngioma. Pract Radiat Oncol. 2012 Oct-Dec; 2(4):314-318. PMID: 24674170.
      Citations: 2     Fields:    
    170. Amsbaugh MJ, Grosshans DR, McAleer MF, Zhu R, Wages C, Crawford CN, Palmer M, De Gracia B, Woo S, Mahajan A. Proton therapy for spinal ependymomas: planning, acute toxicities, and preliminary outcomes. Int J Radiat Oncol Biol Phys. 2012 Aug 01; 83(5):1419-24. PMID: 22245209.
      Citations: 16     Fields:    Translation:HumansPHPublic Health
    171. Boehling NS, Grosshans DR, Allen PK, McAleer MF, Burton AW, Azeem S, Rhines LD, Chang EL. Vertebral compression fracture risk after stereotactic body radiotherapy for spinal metastases. J Neurosurg Spine. 2012 Apr; 16(4):379-86. PMID: 22225488.
      Citations: 58     Fields:    Translation:Humans
    172. Pinnix CC, Fontanilla HP, Hayes-Jordan A, Subbiah V, Bilton SD, Chang EL, Grosshans DR, McAleer MF, Sulman EP, Woo SY, Anderson P, Green HL, Mahajan A. Whole abdominopelvic intensity-modulated radiation therapy for desmoplastic small round cell tumor after surgery. Int J Radiat Oncol Biol Phys. 2012 May 01; 83(1):317-26. PMID: 22104361; PMCID: PMC4005898.
      Citations: 19     Fields:    Translation:Humans
    173. Grosshans D, Boehling NS, Palmer M, Spicer C, Erice R, Cox JD, Komaki R, Chang JY. Improving cardiac dosimetry: Alternative beam arrangements for intensity modulated radiation therapy planning in patients with carcinoma of the distal esophagus. Pract Radiat Oncol. 2012 Jan-Mar; 2(1):41-5. PMID: 24674035.
      Citations: 6     Fields:    
    174. Moeller BJ, Chintagumpala M, Philip JJ, Grosshans DR, McAleer MF, Woo SY, Gidley PW, Vats TS, Mahajan A. Low early ototoxicity rates for pediatric medulloblastoma patients treated with proton radiotherapy. Radiat Oncol. 2011 Jun 02; 6:58. PMID: 21635776; PMCID: PMC3123575.
      Citations: 24     Fields:    Translation:Humans
    175. Boehling NS, Grosshans DR, Bluett JB, Palmer MT, Song X, Amos RA, Sahoo N, Meyer JJ, Mahajan A, Woo SY. Dosimetric comparison of three-dimensional conformal proton radiotherapy, intensity-modulated proton therapy, and intensity-modulated radiotherapy for treatment of pediatric craniopharyngiomas. Int J Radiat Oncol Biol Phys. 2012 Feb 01; 82(2):643-52. PMID: 21277111.
      Citations: 48     Fields:    Translation:Humans
    176. Grosshans DR, Meyers CA, Allen PK, Davenport SD, Komaki R. Neurocognitive function in patients with small cell lung cancer : effect of prophylactic cranial irradiation. Cancer. 2008 Feb 01; 112(3):589-95. PMID: 18098269.
      Citations: 35     Fields:    Translation:HumansCTClinical Trials
    177. Hellier JL, Grosshans DR, Coultrap SJ, Jones JP, Dobelis P, Browning MD, Staley KJ. NMDA receptor trafficking at recurrent synapses stabilizes the state of the CA3 network. J Neurophysiol. 2007 Nov; 98(5):2818-26. PMID: 17728388.
      Citations: 9     Fields:    Translation:AnimalsCells
    178. Alvestad RM, Grosshans DR, Coultrap SJ, Nakazawa T, Yamamoto T, Browning MD. Tyrosine dephosphorylation and ethanol inhibition of N-Methyl-D-aspartate receptor function. J Biol Chem. 2003 Mar 28; 278(13):11020-5. PMID: 12536146.
      Citations: 39     Fields:    Translation:AnimalsCells
    179. Grosshans DR, Clayton DA, Coultrap SJ, Browning MD. Analysis of glutamate receptor surface expression in acute hippocampal slices. Sci STKE. 2002 Jun 18; 2002(137):pl8. PMID: 12072555.
      Citations: 28     Fields:    Translation:Animals
    180. Clayton DA, Grosshans DR, Browning MD. Aging and surface expression of hippocampal NMDA receptors. J Biol Chem. 2002 Apr 26; 277(17):14367-9. PMID: 11891215.
      Citations: 33     Fields:    Translation:Animals
    181. Grosshans DR, Clayton DA, Coultrap SJ, Browning MD. LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1. Nat Neurosci. 2002 Jan; 5(1):27-33. PMID: 11740502.
      Citations: 142     Fields:    Translation:AnimalsCells
    182. Grosshans DR, Browning MD. Protein kinase C activation induces tyrosine phosphorylation of the NR2A and NR2B subunits of the NMDA receptor. J Neurochem. 2001 Feb; 76(3):737-44. PMID: 11158244.
      Citations: 26     Fields:    Translation:AnimalsCells
    183. Oh JJ, Grosshans DR, Wong SG, Slamon DJ. Identification of differentially expressed genes associated with HER-2/neu overexpression in human breast cancer cells. Nucleic Acids Res. 1999 Oct 15; 27(20):4008-17. PMID: 10497265; PMCID: PMC148668.
      Citations: 37     Fields:    Translation:HumansCells
    184. Wilson CA, Payton MN, Elliott GS, Buaas FW, Cajulis EE, Grosshans D, Ramos L, Reese DM, Slamon DJ, Calzone FJ. Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-delta11b. Oncogene. 1997 Jan 09; 14(1):1-16. PMID: 9010228.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    185. Spot scanning proton therapy for craniopharyngioma. Practical Radiation Oncology. 2:314-318.
    186. Spatial mapping of the biologic effectiveness of scanned particle beams. Scientific Reports. 5.
    187. Spot scanning proton therapy minimizes neutron dose in the setting of radiation therapy administered during pregnancy. Journal of Applied Clinical Medical Physics. 17:366-376.
    188. Catechol-o-methyltransferase genotype modulates cancer treatment-related cognitive deficits in breast cancer survivors. Breast Diseases. 22:411-412.
    189. A multi-institutional pilot survey of anesthesia practices during proton radiation therapy. Practical Radiation Oncology.
    190. Particle therapy for central nervous system tumors in pediatric and adult patients. Translational Cancer Research. 1:137-149.
    191. Comparing intelligence quotient change after treatment with proton versus photon radiation therapy for pediatric brain tumors. Journal of Clinical Oncology. 34:1043-1049.
    192. Proton therapy - Present and future. Advanced Drug Delivery Reviews.
    193. Cutaneous graft-versus-host disease after proton-based craniospinal irradiation for recurrent Philadelphia-positive acute lymphoblastic leukaemia. BMJ Case Reports.
    194. Clinical evidence of variable proton biological effectiveness in pediatric patients treated for ependymoma. Radiotherapy and Oncology. 121:395-401.
    195. Proton therapy for paediatric medulloblastoma. The Lancet Oncology. 17:258-259.
    196. Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant 4 Monte Carlo code. Medical Physics. 42:6234-6247.
    197. Impact of heart and lung dose on early survival in patients with non-small cell lung cancer treated with chemoradiation. Radiotherapy and Oncology.
    198. Proton versus conventional radiotherapy for pediatric salivary gland tumors. Radiotherapy and Oncology.
    199. Improving cardiac dosimetry. Practical Radiation Oncology. 2:41-45.
    200. Monte Carlo simulations of 3He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness. Medical Physics. 43:761-776.
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