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JASON HUSE

TitleAssociate Professor
InstitutionMD Anderson
DepartmentPathology
Address2130 W Holcombe Blvd
Houston TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. van den Bent MJ, French PJ, Brat D, Tonn JC, Touat M, Ellingson BM, Young RJ, Pallud J, von Deimling A, Sahm F, Figarella Branger D, Huang RY, Weller M, Mellinghoff IK, Cloughsey TF, Huse JT, Aldape K, Reifenberger G, Youssef G, Karschnia P, Noushmehr H, Peters KB, Ducray F, Preusser M, Wen PY, van den Bent MJ, French PJ, Brat D, Tonn JC, Touat M, Ellingson BM, Young RJ, Pallud J, von Deimling A, Sahm F, Huang RY, Mellinghoff IK, Cloughsey TF, Huse JT, Aldape K, Reifenberger G, Youssef G, Karschnia P, Peters KB, Ducray F, Wen PY. The biological significance of tumor grade, age, enhancement, and extent of resection in IDH-mutant gliomas: How should they inform treatment decisions in the era of IDH inhibitors? Neuro Oncol. 2024 Oct 03; 26(10):1805-1822. PMID: 38912846; PMCID: PMC11449017.
      Citations: 1     Fields:    Translation:Humans
    2. Hotchkiss KM, Karschnia P, Schreck KC, Geurts M, Cloughesy TF, Huse J, Duke ES, Lathia J, Ashley DM, Nduom EK, Long G, Singh K, Chalmers A, Ahluwalia MS, Heimberger A, Bagley S, Todo T, Verhaak R, Kelly PD, Hervey-Jumper S, de Groot J, Patel A, Fecci P, Parney I, Wykes V, Watts C, Burns TC, Sanai N, Preusser M, Tonn JC, Drummond KJ, Platten M, Das S, Tanner K, Vogelbaum MA, Weller M, Whittle JR, Berger MS, Khasraw M. A brave new framework for glioma drug development. Lancet Oncol. 2024 Oct; 25(10):e512-e519. PMID: 39362262.
      Citations:    Fields:    Translation:Humans
    3. Yuzhalin AE, Lowery FJ, Saito Y, Yuan X, Yao J, Duan Y, Ding J, Acharya S, Zhang C, Fajardo A, Chen HN, Wei Y, Sun Y, Zhang L, Xiao Y, Li P, Lorenzi PL, Huse JT, Fan H, Zhao Z, Hung MC, Yu D. Astrocyte-induced Cdk5 expedites breast cancer brain metastasis by suppressing MHC-I expression to evade immune recognition. Nat Cell Biol. 2024 Oct; 26(10):1773-1789. PMID: 39304713.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    4. Watson SS, Zomer A, Fournier N, Lourenco J, Quadroni M, Chryplewicz A, Nassiri S, Aubel P, Avanthay S, Croci D, Abels E, Broekman MLD, Hanahan D, Huse JT, Daniel RT, Hegi ME, Homicsko K, Cossu G, Hottinger AF, Joyce JA. Fibrotic response to anti-CSF-1R therapy potentiates glioblastoma recurrence. Cancer Cell. 2024 Sep 09; 42(9):1507-1527.e11. PMID: 39255775.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Gupta P, Dang M, Oberai S, Migliozzi S, Trivedi R, Kumar G, Peshoff M, Milam N, Ahmed A, Bojja K, Tran TM, Gumin J, Kamiya-Matsuoka C, Huse J, Cox K, Li J, Shehwana H, Sheth SA, Saxon R, Baohua S, Parker-Kerrigan B, Maheshwari A, Parra Cuentas ER, Navin NE, Heimberger AB, Lang FF, Iavarone A, Clise-Dwyer K, Wang L, Bhat KP. Immune landscape of isocitrate dehydrogenase-stratified primary and recurrent human gliomas. Neuro Oncol. 2024 Aug 10. PMID: 39126294.
      Citations: 2     Fields:    
    6. Glitza Oliva IC, Ferguson SD, Bassett R, Foster AP, John I, Hennegan TD, Rohlfs M, Richard J, Iqbal M, Dett T, Lacey C, Jackson N, Rodgers T, Phillips S, Duncan S, Haydu L, Lin R, Amaria RN, Wong MK, Diab A, Yee C, Patel SP, McQuade JL, Fischer GM, McCutcheon IE, O'Brien BJ, Tummala S, Debnam M, Guha-Thakurta N, Wargo JA, Carapeto FCL, Hudgens CW, Huse JT, Tetzlaff MT, Burton EM, Tawbi HA, Davies MA. Author Correction: Concurrent intrathecal and intravenous nivolumab in leptomeningeal disease: phase 1 trial interim results. Nat Med. 2024 Jun; 30(6):1787. PMID: 38649781; PMCID: PMC11186776.
      Citations:    Fields:    
    7. Peshoff MM, Gupta P, Oberai S, Trivedi R, Katayama H, Chakrapani P, Dang M, Migliozzi S, Gumin J, Kadri DB, Lin JK, Milam NK, Maynard ME, Vaillant BD, Parker-Kerrigan B, Lang FF, Huse JT, Iavarone A, Wang L, Clise-Dwyer K, Bhat KP, Peshoff MM, Gupta P, Oberai S, Trivedi R, Katayama H, Chakrapani P, Dang M, Migliozzi S, Gumin J, Kadri DB, Lin JK, Milam NK, Maynard ME, Vaillant BD, Parker-Kerrigan B, Lang FF, Huse JT, Iavarone A, Wang L, Clise-Dwyer K, Bhat KP. Triggering receptor expressed on myeloid cells 2 (TREM2) regulates phagocytosis in glioblastoma. Neuro Oncol. 2024 May 03; 26(5):826-839. PMID: 38237157; PMCID: PMC11066944.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    8. Ene CI, Abi Faraj C, Beckham TH, Weinberg JS, Andersen CR, Haider AS, Rao G, Ferguson SD, Alvarez-Brenkenridge CA, Kim BYS, Heimberger AB, McCutcheon IE, Prabhu SS, Wang CM, Ghia AJ, McGovern SL, Chung C, McAleer MF, Tom MC, Perni S, Swanson TA, Yeboa DN, Briere TM, Huse JT, Fuller GN, Lang FF, Li J, Suki D, Sawaya RE. Response of treatment-naive brain metastases to stereotactic radiosurgery. Nat Commun. 2024 May 02; 15(1):3728. PMID: 38697991; PMCID: PMC11066027.
      Citations: 1     Fields:    Translation:Humans
    9. Kumar VA, Perez A, Young AL, Jones J, O'Brien BJ, Lang FF, Huse JT, Fuller GN. Collision tumor: Multinodular and vacuolating neuronal tumor with isocitrate dehydrogenase-mutant diffuse astrocytoma. Neuropathology. 2024 Oct; 44(5):333-337. PMID: 38414131.
      Citations:    Fields:    Translation:Humans
    10. Hariharan S, Whitfield BT, Pirozzi CJ, Waitkus MS, Brown MC, Bowie ML, Irvin DM, Roso K, Fuller R, Hostettler J, Dharmaiah S, Gibson EA, Briley A, Mangoli A, Fraley C, Shobande M, Stevenson K, Zhang G, Malgulwar PB, Roberts H, Roskoski M, Spasojevic I, Keir ST, He Y, Castro MG, Huse JT, Ashley DM. Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas. Nat Commun. 2024 Jan 25; 15(1):730. PMID: 38272925; PMCID: PMC10810843.
      Citations: 2     Fields:    Translation:Humans
    11. Zhu Y, Zhang D, Shukla P, Jung YH, Malgulwar PB, Chagani S, Colic M, Benjamin S, Copland JA, Tan L, Lorenzi PL, Javle M, Huse JT, Roszik J, Hart T, Kwong LN. CRISPR screening identifies BET and mTOR inhibitor synergy in cholangiocarcinoma through serine glycine one carbon. JCI Insight. 2024 Jan 23; 9(2). PMID: 38060314; PMCID: PMC10906219.
      Citations:    Fields:    Translation:HumansCells
    12. Gubbiotti MA, Weinberg JS, Weathers SP, Dasgupta P, Tom MC, Aldape K, Quezado M, Abdullaev Z, Huse JT, Ballester LY. An incidental finding of a high-grade glioma with pleomorphic and pseudopapillary features (HPAP) with PBRM1 mutation. J Neuropathol Exp Neurol. 2024 01 19; 83(2):139-141. PMID: 38164987; PMCID: PMC11032702.
      Citations:    Fields:    Translation:Humans
    13. Wang DH, Fujita Y, Dono A, Rodriguez Armendariz AG, Shah M, Putluri N, Pichardo-Rojas PS, Patel CB, Zhu JJ, Huse JT, Parker Kerrigan BC, Lang FF, Esquenazi Y, Ballester LY. The genomic alterations in glioblastoma influence the levels of CSF metabolites. Acta Neuropathol Commun. 2024 Jan 19; 12(1):13. PMID: 38243318; PMCID: PMC10799404.
      Citations: 3     Fields:    Translation:Humans
    14. Malgulwar PB, Danussi C, Dharmaiah S, Johnson W, Singh A, Rai K, Rao A, Huse JT. Sirtuin 2 inhibition modulates chromatin landscapes genome-wide to induce senescence in ATRX-deficient malignant glioma. Neuro Oncol. 2024 01 05; 26(1):55-67. PMID: 37625115; PMCID: PMC10769000.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    15. Kan P, Srinivasan VM, Gumin J, Garcia R, Chen SR, Johnson JN, Collins DE, Chen MM, Ledbetter D, Huse J, Evan Luna ZA, Robledo A, Vasandani V, Rao A, Singh SK, Shpall EJ, Fueyo J, Gomez-Manzano C, Lang FF. Development of a rabbit human glioblastoma model for testing of endovascular selective intra-arterial infusion (ESIA) of novel stem cell-based therapeutics. Neuro Oncol. 2024 01 05; 26(1):127-136. PMID: 37603323; PMCID: PMC10768973.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    16. Yu KKH, Basu S, Baquer G, Ahn R, Gantchev J, Jindal S, Regan MS, Abou-Mrad Z, Prabhu MC, Williams MJ, D'Souza AD, Malinowski SW, Hopland K, Elhanati Y, Stopka SA, Stortchevoi A, He Z, Sun J, Chen Y, Espejo AB, Chow KH, Yerrum S, Kao PL, Kerrigan BP, Norberg L, Nielsen D, GBM TeamLab, Puduvalli VK, Huse J, Beroukhim R, Kim YSB, Goswami S, Boire A, Frisken S, Cima MJ, Holdhoff M, Lucas CG, Bettegowda C, Levine SS, Bale TA, Brennan C, Reardon DA, Lang FF, Antonio Chiocca E, Ligon KL, White FM, Sharma P, Tabar V, Agar NYR. Investigative needle core biopsies for multi-omics in Glioblastoma. medRxiv. 2023 Dec 31. PMID: 38234840; PMCID: PMC10793534.
      Citations:    
    17. De A, Lattier JM, Morales JE, Kelly JR, Zheng X, Chen Z, Sebastian S, Nassiri Toosi Z, Huse JT, Lang FF, McCarty JH. Glial Cell Adhesion Molecule (GlialCAM) Determines Proliferative versus Invasive Cell States in Glioblastoma. J Neurosci. 2023 11 22; 43(47):8043-8057. PMID: 37722850; PMCID: PMC10669794.
      Citations: 1     Fields:    Translation:Humans
    18. Karschnia P, Smits M, Reifenberger G, Le Rhun E, Ellingson BM, Galldiks N, Kim MM, Huse JT, Schnell O, Harter PN, Mohme M, Expert Rater Panel, von Baumgarten L, Albert NL, Huang RY, Mehta MP, van den Bent M, Weller M, Vogelbaum MA, Chang SM, Berger MS, Tonn JC. A framework for standardised tissue sampling and processing during resection of diffuse intracranial glioma: joint recommendations from four RANO groups. Lancet Oncol. 2023 11; 24(11):e438-e450. PMID: 37922934; PMCID: PMC10849105.
      Citations:    Fields:    Translation:Humans
    19. Bhamidipati D, Yedururi S, Huse J, Chinapuvvula SV, Wu J, Subbiah V. Exceptional Responses to Selpercatinib in RET Fusion-Driven Metastatic Pancreatic Cancer. JCO Precis Oncol. 2023 09; 7:e2300252. PMID: 38039431.
      Citations:    Fields:    Translation:Humans
    20. Shiau CK, Lu L, Kieser R, Fukumura K, Pan T, Lin HY, Yang J, Tong EL, Lee G, Yan Y, Huse JT, Gao R. High throughput single cell long-read sequencing analyses of same-cell genotypes and phenotypes in human tumors. Nat Commun. 2023 07 11; 14(1):4124. PMID: 37433798; PMCID: PMC10336110.
      Citations: 5     Fields:    Translation:Humans
    21. Hasanov M, Milton DR, Davies AB, Sirmans E, Saberian C, Posada EL, Opusunju S, Gershenwald JE, Torres-Cabala CA, Burton EM, Colen RR, Huse JT, Glitza Oliva IC, Chung C, McAleer MF, McGovern SL, Yeboa DN, Kim BYS, Prabhu SS, McCutcheon IE, Weinberg JS, Lang FF, Tawbi HA, Li J, Haydu LE, Davies MA, Ferguson SD. Changes in outcomes and factors associated with survival in melanoma patients with brain metastases. Neuro Oncol. 2023 Jul 06; 25(7):1310-1320. PMID: 36510640; PMCID: PMC10326492.
      Citations: 1     Fields:    Translation:Humans
    22. Nelson BE, Reddy NK, Huse JT, Amini B, Nardo M, Gouda M, Weathers SP, Subbiah V. Histological transformation to gliosarcoma with combined BRAF/MEK inhibition in BRAF V600E mutated glioblastoma. NPJ Precis Oncol. 2023 May 25; 7(1):47. PMID: 37231247; PMCID: PMC10212928.
      Citations: 1     
    23. Hariharan S, Whitfield BT, Pirozzi CJ, Waitkus MS, Brown MC, Bowie ML, Irvin DM, Roso K, Fuller R, Hostettler J, Dharmaiah S, Gibson EA, Briley A, Mangoli A, Fraley C, Shobande M, Stevenson K, Zhang G, Malgulwar PB, Roberts H, Roskoski M, Spasojevic I, Keir ST, He Y, Castro MG, Huse JT, Ashley DM. Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas. bioRxiv. 2023 Apr 21. PMID: 37131619; PMCID: PMC10153255.
      Citations:    
    24. Gregory TA, Mastall M, Lin H, Hess KR, Yuan Y, Martin-Bejarano Garcia M, Fuller GN, Alfaro KD, Gule-Monroe MK, Huse JT, Khatua S, Rao G, Sandberg DI, Wefel JS, Yeboa DN, Paulino AC, McGovern SL, Zaky W, Mahajan A, Suki D, Weathers SP, Harrison RA, de Groot JF, Puduvalli VK, Penas-Prado M, Majd NK. Characterization of recurrence patterns and outcomes of medulloblastoma in adults: The University of Texas MD Anderson Cancer Center experience. Neurooncol Adv. 2023 Jan-Dec; 5(1):vdad032. PMID: 37114244; PMCID: PMC10129387.
      Citations:    
    25. Peshoff MM, Gupta P, Trivedi R, Oberai S, Chakrapani P, Dang M, Milam N, Maynard ME, Vaillant BD, Huse JT, Wang L, Clise-Dwyer K, Bhat KP. Triggering receptor expressed on myeloid cells 2 (TREM2) regulates phagocytosis in glioblastoma. bioRxiv. 2023 Apr 06. PMID: 37066184; PMCID: PMC10104029.
      Citations:    
    26. Glitza Oliva IC, Ferguson SD, Bassett R, Foster AP, John I, Hennegan TD, Rohlfs M, Richard J, Iqbal M, Dett T, Lacey C, Jackson N, Rodgers T, Phillips S, Duncan S, Haydu L, Lin R, Amaria RN, Wong MK, Diab A, Yee C, Patel SP, McQuade JL, Fischer GM, McCutcheon IE, O'Brien BJ, Tummala S, Debnam M, Guha-Thakurta N, Wargo JA, Burton EM, Tawbi HA, Davies MA, Carapeto FCL, Hudgens CW, Huse JT, Tetzlaff MT. Concurrent intrathecal and intravenous nivolumab in leptomeningeal disease: phase 1 trial interim results. Nat Med. 2023 04; 29(4):898-905. PMID: 36997799; PMCID: PMC10115650.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    27. Ozkizilkaya HI, Johnson JM, O'Brien BJ, McCutcheon IE, Prabhu SS, Ghia AJ, Fuller GN, Huse JT, Ballester LY. Intracranial mesenchymal tumor, FET::CREB fusion-positive in the lateral ventricle. Neurooncol Adv. 2023 Jan-Dec; 5(1):vdad026. PMID: 37051329; PMCID: PMC10084497.
      Citations:    
    28. Jahedi A, Kumar G, Kannan L, Agarwal T, Huse J, Bhat K, Kannan K. Gibbs process distinguishes survival and reveals contact-inhibition genes in Glioblastoma multiforme. PLoS One. 2023; 18(2):e0277176. PMID: 36795646; PMCID: PMC9934342.
      Citations:    Fields:    Translation:HumansCells
    29. Walsh KM, Neff C, Bondy ML, Kruchko C, Huse JT, Amos CI, Barnholtz-Sloan JS, Ostrom QT. Influence of county-level geographic/ancestral origin on glioma incidence and outcomes in US Hispanics. Neuro Oncol. 2023 02 14; 25(2):398-406. PMID: 35868246; PMCID: PMC9925707.
      Citations:    Fields:    
    30. Shiau CK, Lu L, Kieser R, Fukumura K, Pan T, Lin HY, Yang J, Tong EL, Lee G, Yan Y, Huse JT, Gao R. Delineating genotypes and phenotypes of individual cells from long-read single cell transcriptomes. bioRxiv. 2023 Feb 03. PMID: 36778278; PMCID: PMC9915466.
      Citations:    
    31. Malgulwar PB, Danussi C, Dharmaiah S, Johnson WE, Rao A, Huse JT. Sirtuin 2 inhibition modulates chromatin landscapes genome-wide to induce senescence in ATRX-deficient malignant glioma. bioRxiv. 2023 Jan 10. PMID: 36711727; PMCID: PMC9882017.
      Citations:    
    32. Huse JT. A promising preclinical model for TERT promoter mutation in glioblastoma. Neuro Oncol. 2022 12 01; 24(12):2076-2077. PMID: 35780432; PMCID: PMC9713493.
      Citations:    Fields:    
    33. Gates EDH, Suki D, Celaya A, Weinberg JS, Prabhu SS, Sawaya R, Huse JT, Long JP, Fuentes D, Schellingerhout D. Cellular Density in Adult Glioma, Estimated with MR Imaging Data and a Machine Learning Algorithm, Has Prognostic Power Approaching World Health Organization Histologic Grading in a Cohort of 1181 Patients. AJNR Am J Neuroradiol. 2022 10; 43(10):1411-1417. PMID: 36109124; PMCID: PMC9575543.
      Citations:    
    34. Yang J, Wang Q, Zhang ZY, Long L, Ezhilarasan R, Karp JM, Tsirigos A, Snuderl M, Wiestler B, Wick W, Miao Y, Huse JT, Sulman EP. DNA methylation-based epigenetic signatures predict somatic genomic alterations in gliomas. Nat Commun. 2022 07 29; 13(1):4410. PMID: 35906213; PMCID: PMC9338285.
      Citations:    Fields:    
    35. Warner E, Li X, Rao G, Huse J, Traylor J, Ravikumar V, Monga V, Rao A. Investigating Useful Features for Overall Survival Prediction in Patients with Low-Grade Glioma Using Histology Slides. Annu Int Conf IEEE Eng Med Biol Soc. 2022 07; 2022:4938-4941. PMID: 36085890.
      Citations:    
    36. Varn FS, Johnson KC, Martinek J, Huse JT, Nasrallah MP, Cooper LAD, Wade TE, Sabedot TS, Brat D, Aldape K, Ismail A, Sivajothi SK, Barthel FP, Kim H, Kocakavuk E, Ahmed N, White K, Datta I, Moon HE, Pollock S, Goldfarb C, Lee GH, Garofano L, Anderson KJ, Nehar-Belaid D, Barnholtz-Sloan JS, Bakas S, Byrne AT, D'Angelo F, Gan HK, Khasraw M, Migliozzi S, Ormond DR, Paek SH, Van Meir EG, Walenkamp AME, Watts C, Palucka K, Stead LF, Poisson LM, Noushmehr H, Iavarone A, Verhaak RGW, GLASS Consortium, Wesseling P, Malta TM, Gould PV, W?ehrer A, Weiss T, Weller M. Glioma progression is shaped by genetic evolution and microenvironment interactions. Cell. 2022 06 09; 185(12):2184-2199.e16. PMID: 35649412; PMCID: PMC9189056.
      Citations:    Fields:    Translation:Humans
    37. Groot J, Ott M, Wei J, Kassab C, Fang D, O'Brien B, Weathers SP, Matsouka CK, Majd NK, Harrison RA, Fuller GN, Huse JT, Long JP, Sawaya R, Rao G, MacDonald TJ, Priebe W, Najem H, DeCuypere M, Heimberger AB. A first-in-human Phase I trial of the oral p-STAT3 inhibitor WP1066 in patients with recurrent malignant glioma. CNS Oncol. 2022 06 01; 11(2):CNS87. PMID: 35575067; PMCID: PMC9134932.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    38. Najem H, Ott M, Kassab C, Rao A, Rao G, Marisetty A, Sonabend AM, Horbinski C, Verhaak R, Shankar A, Krishnan SN, Varn FS, Gupta P, Ferguson SD, Huse JT, Fuller GN, Long JP, Winkowski DE, Freiberg BA, James CD, Platanias LC, Lesniak MS, Burks JK, Heimberger AB, Arrieta VA. Central nervous system immune interactome is a function of cancer lineage, tumor microenvironment, and STAT3 expression. JCI Insight. 2022 05 09; 7(9). PMID: 35316217; PMCID: PMC9090258.
      Citations: 1     Fields:    Translation:HumansCells
    39. Brat DJ, Aldape K, Bridge JA, Canoll P, Colman H, Hameed MR, Harris BT, Hattab EM, Huse JT, Jenkins RB, Lopez-Terrada DH, McDonald WC, Rodriguez FJ, Souter LH, Colasacco C, Thomas NE, Yount MH, van den Bent MJ, Perry A. Molecular Biomarker Testing for the Diagnosis of Diffuse Gliomas. Arch Pathol Lab Med. 2022 05 01; 146(5):547-574. PMID: 35175291; PMCID: PMC9311267.
      Citations:    Fields:    Translation:Humans
    40. Whitfield BT, Huse JT. Classification of adult-type diffuse gliomas: Impact of the World Health Organization 2021 update. Brain Pathol. 2022 07; 32(4):e13062. PMID: 35289001; PMCID: PMC9245936.
      Citations: 3     Fields:    Translation:Humans
    41. Dharmaiah S, Huse JT. The epigenetic dysfunction underlying malignant glioma pathogenesis. Lab Invest. 2022 07; 102(7):682-690. PMID: 35152274.
      Citations:    Fields:    Translation:Humans
    42. Qin T, Mullan B, Ravindran R, Messinger D, Siada R, Cummings JR, Harris M, Muruganand A, Pyaram K, Miklja Z, Reiber M, Garcia T, Tran D, Danussi C, Brosnan-Cashman J, Pratt D, Zhao X, Rehemtulla A, Sartor MA, Venneti S, Meeker AK, Huse JT, Morgan MA, Lowenstein PR, Castro MG, Yadav VN, Koschmann C. ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization. Cell Rep. 2022 01 11; 38(2):110216. PMID: 35021084; PMCID: PMC8759735.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    43. Danussi C, Bose P, Parthasarathy PT, Silberman PC, Van Arnam JS, Vitucci M, Tang OY, Heguy A, Wang Y, Chan TA, Riggins GJ, Sulman EP, Lang FF, Creighton CJ, Deneen B, Miller CR, Picketts DJ, Kannan K, Huse JT. Author Correction: Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling. Nat Commun. 2022 Jan 05; 13(1):190. PMID: 34987156; PMCID: PMC8733027.
      Citations:    Fields:    
    44. Perez A, Huse JT. The Evolving Classification of Diffuse Gliomas: World Health Organization Updates for 2021. Curr Neurol Neurosci Rep. 2021 11 24; 21(12):67. PMID: 34817712.
      Citations: 2     Fields:    Translation:Humans
    45. Najem H, Marisetty A, Horbinski C, Long J, Huse JT, Glitza Oliva IC, Ferguson SD, Kumthekar PU, Wainwright DA, Chen P, Lesniak MS, Burks JK, Heimberger AB. CD11c+CD163+ Cells and Signal Transducer and Activator of Transcription 3 (STAT3) Expression Are Common in Melanoma Leptomeningeal Disease. Front Immunol. 2021; 12:745893. PMID: 34691054; PMCID: PMC8531809.
      Citations: 1     Fields:    Translation:HumansCells
    46. Lukas RV, Razis ED, Huse JT. An international perspective on the management of glioblastoma. Chin Clin Oncol. 2021 08; 10(4):40. PMID: 34496599.
      Citations:    Fields:    Translation:Humans
    47. Barekatain Y, Ackroyd JJ, Yan VC, Khadka S, Wang L, Chen KC, Poral AH, Tran T, Georgiou DK, Arthur K, Lin YH, Satani N, Ballato ES, Behr EI, deCarvalho AC, Verhaak RGW, de Groot J, Huse JT, Asara JM, Kalluri R, Muller FL. Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine. Nat Commun. 2021 07 09; 12(1):4228. PMID: 34244484; PMCID: PMC8270912.
      Citations: 2     Fields:    Translation:HumansCells
    48. Majd NK, Mastall M, Lin H, Dibaj SS, Hess KR, Yuan Y, Fuller GN, Alfaro KD, Gule-Monroe MK, Huse JT, Khatua S, Rao G, Sandberg DI, Wefel JS, Yeboa DN, Paulino AC, McGovern SL, Zaky W, Mahajan A, Suki D, Weathers SP, Harriso RA, De Groo JF, Puduvalli VK, Penas-Prado M, Garcia MM. Clinical characterization of adult medulloblastoma and the effect of first-line therapies on outcome; The MD Anderson Cancer Center experience. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab079. PMID: 34377987; PMCID: PMC8350154.
      Citations: 1     
    49. Sirintrapun SJ, Reales D, Al-Ahmadie HA, Dogan A, Arcila M, Zehir A, Maron S, Viaplana C, Janeway K, Ducar M, Sholl L, Dogan S, Surrey LF, Sanchez IH, Syed A, Rema AB, Iyer GV, Murali R, Bouvier N, Soslow RA, Hyman D, Younes A, Intlekofer A, Harding JJ, Carvajal RD, Sabbatini PJ, Abou-Alfa GK, Morris L, Janjigian YY, Gallagher MM, Soumerai TA, Mellinghoff IK, Hakimi AA, Fury M, Huse JT, Bagrodia A, Hameed M, Thomas S, Gardos S, Cerami E, Mazor T, Kumari P, Raman P, Shivdasani P, MacFarland S, Newman S, Waanders A, Kundra R, Zhang H, Sheridan R, Wang A, Ochoa A, Wilson M, Gross B, Sun Y, Madupuri R, Satravada BA, Vakiani E, Berger MF, Bedard P, Chakravarty D, Suehnholz S, Nissan M, Gao J, Solit D, Schultz N. OncoTree: A Cancer Classification System for Precision Oncology. JCO Clin Cancer Inform. 2021 02; 5:221-230. PMID: 33625877; PMCID: PMC8240791.
      Citations: 8     Fields:    Translation:Humans
    50. Fukumura K, Malgulwar PB, Fischer GM, Hu X, Mao X, Song X, Hernandez SD, Zhang XH, Zhang J, Parra ER, Yu D, Debeb BG, Davies MA, Huse JT. Multi-omic molecular profiling reveals potentially targetable abnormalities shared across multiple histologies of brain metastasis. Acta Neuropathol. 2021 02; 141(2):303-321. PMID: 33394124; PMCID: PMC7852029.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    51. Lee WC, Reuben A, Hu X, McGranahan N, Chen R, Jalali A, Negrao MV, Hubert SM, Tang C, Wu CC, Lucas AS, Roh W, Suda K, Kim J, Tan AC, Peng DH, Lu W, Tang X, Chow CW, Fujimoto J, Behrens C, Kalhor N, Fukumura K, Coyle M, Thornton R, Gumbs C, Li J, Wu CJ, Little L, Roarty E, Song X, Lee JJ, Sulman EP, Rao G, Swisher S, Diao L, Wang J, Heymach JV, Huse JT, Scheet P, Wistuba II, Gibbons DL, Futreal PA, Zhang J, Gomez D, Zhang J. Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity. Genome Biol. 2020 11 04; 21(1):271. PMID: 33148332; PMCID: PMC7640699.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    52. Chang G, Shi L, Ye Y, Shi H, Zeng L, Tiwary S, Huse JT, Huo L, Ma L, Ma Y, Zhang S, Zhu J, Xie V, Li P, Han L, He C, Huang S. YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis. Cancer Cell. 2020 12 14; 38(6):857-871.e7. PMID: 33125861; PMCID: PMC7738369.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    53. Lattier JM, De A, Chen Z, Morales JE, Lang FF, Huse JT, McCarty JH. Megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1) promotes glioblastoma cell invasion in the brain microenvironment. Oncogene. 2020 12; 39(50):7253-7264. PMID: 33040087; PMCID: PMC7736299.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    54. Ott M, Tomaszowski KH, Marisetty A, Kong LY, Wei J, Duna M, Blumberg K, Ji X, Jacobs C, Fuller GN, Langford LA, Huse JT, Long JP, Hu J, Li S, Weinberg JS, Prabhu SS, Sawaya R, Ferguson S, Rao G, Lang FF, Curran MA, Heimberger AB. Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration. JCI Insight. 2020 09 03; 5(17). PMID: 32721947; PMCID: PMC7526457.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    55. Akkari L, Bowman RL, Tessier J, Klemm F, Handgraaf SM, de Groot M, Quail DF, Tillard L, Gadiot J, Huse JT, Brandsma D, Westerga J, Watts C, Joyce JA. Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance. Sci Transl Med. 2020 07 15; 12(552). PMID: 32669424.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    56. Barekatain Y, Yan VC, Arthur K, Ackroyd JJ, Khadka S, De Groot J, Huse JT, Muller FL. Robust detection of oncometabolic aberrations by 1H-13C heteronuclear single quantum correlation in intact biological specimens. Commun Biol. 2020 06 25; 3(1):328. PMID: 32587392; PMCID: PMC7316726.
      Citations:    Translation:HumansAnimalsCells
    57. Zhang L, Yao J, Wei Y, Zhou Z, Li P, Qu J, Badu-Nkansah A, Yuan X, Huang YW, Fukumura K, Mao X, Chang WC, Saunus J, Lakhani S, Huse JT, Hung MC, Yu D. Blocking immunosuppressive neutrophils deters pY696-EZH2-driven brain metastases. Sci Transl Med. 2020 05 27; 12(545). PMID: 32461334; PMCID: PMC7948522.
      Citations: 21     Fields:    Translation:AnimalsCells
    58. de Blank P, Fouladi M, Huse JT. Molecular markers and targeted therapy in pediatric low-grade glioma. J Neurooncol. 2020 Oct; 150(1):5-15. PMID: 32399739.
      Citations: 9     Fields:    Translation:Humans
    59. Wang Y, Wild AT, Turcan S, Wu WH, Sigel C, Klimstra DS, Ma X, Gong Y, Holland EC, Huse JT, Chan TA. Targeting therapeutic vulnerabilities with PARP inhibition and radiation in IDH-mutant gliomas and cholangiocarcinomas. Sci Adv. 2020 04; 6(17):eaaz3221. PMID: 32494639; PMCID: PMC7176409.
      Citations: 20     Fields:    
    60. Weathers SP, Penas-Prado M, Pei BL, Ling X, Kassab C, Banerjee P, Bdiwi M, Shaim H, Alsuliman A, Shanley M, de Groot JF, O'Brien BJ, Harrison R, Majd N, Kamiya-Matsuoka C, Fuller GN, Huse JT, Chi L, Rao G, Weinberg JS, Lang FF, Sawaya R, Shpall EJ, Rezvani K, Heimberger AB. Glioblastoma-mediated Immune Dysfunction Limits CMV-specific T Cells and Therapeutic Responses: Results from a Phase I/II Trial. Clin Cancer Res. 2020 07 15; 26(14):3565-3577. PMID: 32299815; PMCID: PMC9347965.
      Citations: 15     Fields:    Translation:HumansCellsCTClinical Trials
    61. de Groot J, Penas-Prado M, Alfaro-Munoz K, Hunter K, Pei BL, O'Brien B, Weathers SP, Loghin M, Kamiya Matsouka C, Yung WKA, Mandel J, Wu J, Yuan Y, Zhou S, Fuller GN, Huse J, Rao G, Weinberg JS, Prabhu SS, McCutcheon IE, Lang FF, Ferguson SD, Sawaya R, Colen R, Yadav SS, Blando J, Vence L, Allison J, Sharma P, Heimberger AB. Window-of-opportunity clinical trial of pembrolizumab in patients with recurrent glioblastoma reveals predominance of immune-suppressive macrophages. Neuro Oncol. 2020 04 15; 22(4):539-549. PMID: 31755915; PMCID: PMC7158647.
      Citations: 41     Fields:    Translation:HumansCells
    62. Haider AS, van den Bent M, Wen PY, Vogelbaum MA, Chang S, Canoll PD, Horbinski CM, Huse JT. Toward a standard pathological and molecular characterization of recurrent glioma in adults: a Response Assessment in Neuro-Oncology effort. Neuro Oncol. 2020 04 15; 22(4):450-456. PMID: 31844891; PMCID: PMC7158649.
      Citations: 13     Fields:    Translation:Humans
    63. Grkovski M, Kohutek ZA, Brennan CW, Tabar VS, Gutin PH, Zhang Z, Young RJ, Beattie BJ, Zanzonico PB, Huse JT, Rosenblum MK, Blasberg RG, Humm JL, Beal K, Sch?der H. 18F-Fluorocholine PET uptake correlates with pathologic evidence of recurrent tumor after stereotactic radiosurgery for brain metastases. Eur J Nucl Med Mol Imaging. 2020 06; 47(6):1446-1457. PMID: 31865407; PMCID: PMC7596690.
      Citations: 9     Fields:    Translation:Humans
    64. Horbinski C, Ligon KL, Brastianos P, Huse JT, Venere M, Chang S, Buckner J, Cloughesy T, Jenkins RB, Giannini C, Stupp R, Nabors LB, Wen PY, Aldape KJ, Lukas RV, Galanis E, Eberhart CG, Brat DJ, Sarkaria JN. The medical necessity of advanced molecular testing in the diagnosis and treatment of brain tumor patients. Neuro Oncol. 2019 12 17; 21(12):1498-1508. PMID: 31276167; PMCID: PMC6917404.
      Citations: 19     Fields:    Translation:Humans
    65. Barthel FP, Johnson KC, Varn FS, Moskalik AD, Tanner G, Kocakavuk E, Anderson KJ, Abiola O, Aldape K, Alfaro KD, Alpar D, Amin SB, Ashley DM, Bandopadhayay P, Barnholtz-Sloan JS, Beroukhim R, Bock C, Brastianos PK, Brat DJ, Brodbelt AR, Bruns AF, Bulsara KR, Chakrabarty A, Chakravarti A, Chuang JH, Claus EB, Cochran EJ, Connelly J, Costello JF, Finocchiaro G, Fletcher MN, French PJ, Gan HK, Gilbert MR, Grimmer MR, Iavarone A, Ismail A, Jenkinson MD, Khasraw M, Kim H, Kouwenhoven MCM, LaViolette PS, Li M, Lichter P, Ligon KL, Lowman AK, Malta TM, Mazor T, McDonald KL, Molinaro AM, Nam DH, Nayyar N, Ng HK, Ngan CY, Niclou SP, Niers JM, Noushmehr H, Noorbakhsh J, Ormond DR, Park CK, Poisson LM, Rabadan R, Radlwimmer B, Rao G, Sa JK, Schuster M, Shaw BL, Short SC, Smitt PAS, Sloan AE, Smits M, Suzuki H, Van Meir EG, Watts C, Weller M, Wesseling P, Westerman BA, Widhalm G, Woehrer A, Yung WKA, Zadeh G, Huse JT, De Groot JF, Stead LF, Verhaak RGW, GLASS Consortium, Gould PV, Reifenberger G, Tabatabai G. Longitudinal molecular trajectories of diffuse glioma in adults. Nature. 2019 12; 576(7785):112-120. PMID: 31748746; PMCID: PMC6897368.
      Citations: 112     Fields:    Translation:HumansCells
    66. Juthani R, Madajewski B, Yoo B, Zhang L, Chen PM, Chen F, Turker MZ, Ma K, Overholtzer M, Longo VA, Carlin S, Aragon-Sanabria V, Huse J, Gonen M, Zanzonico P, Rudin CM, Wiesner U, Bradbury MS, Brennan CW. Ultrasmall Core-Shell Silica Nanoparticles for Precision Drug Delivery in a High-Grade Malignant Brain Tumor Model. Clin Cancer Res. 2020 01 01; 26(1):147-158. PMID: 31515460; PMCID: PMC6942644.
      Citations: 19     Fields:    Translation:AnimalsCells
    67. Kudo Y, Haymaker C, Zhang J, Reuben A, Duose DY, Fujimoto J, Roy-Chowdhuri S, Solis Soto LM, Dejima H, Parra ER, Mino B, Abraham R, Ikeda N, Vaporcyan A, Gibbons D, Zhang J, Lang FF, Luthra R, Lee JJ, Moran C, Huse JT, Kadara H, Wistuba II. Suppressed immune microenvironment and repertoire in brain metastases from patients with resected non-small-cell lung cancer. Ann Oncol. 2019 09 01; 30(9):1521-1530. PMID: 31282941; PMCID: PMC6771224.
      Citations: 38     Fields:    Translation:HumansCells
    68. Kaffes I, Szulzewsky F, Chen Z, Herting CJ, Gabanic B, Shelton J, Switchenko JM, Ross JL, McSwain LF, Huse JT, Westermark B, Nelander S, Forsberg-Nilsson K, Uhrbom L, Maturi NP, Cimino PJ, Holland EC, Brennan CW, Brat DJ, Hambardzumyan D, Vel?zquez Vega JE, Kettenmann H. Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors. Oncoimmunology. 2019; 8(11):e1655360. PMID: 31646100; PMCID: PMC6791439.
      Citations: 39     Fields:    
    69. Gates EDH, Yang J, Fukumura K, Lin JS, Weinberg JS, Prabhu SS, Long L, Fuentes D, Sulman EP, Huse JT, Schellingerhout D. Spatial Distance Correlates With Genetic Distance in Diffuse Glioma. Front Oncol. 2019; 9:676. PMID: 31417865; PMCID: PMC6682615.
      Citations: 4     
    70. Elshafeey N, Kotrotsou A, Hassan A, Elshafei N, Hassan I, Ahmed S, Abrol S, Agarwal A, El Salek K, Bergamaschi S, Acharya J, Moron FE, Law M, Fuller GN, Huse JT, Zinn PO, Colen RR. Multicenter study demonstrates radiomic features derived from magnetic resonance perfusion images identify pseudoprogression in glioblastoma. Nat Commun. 2019 07 18; 10(1):3170. PMID: 31320621; PMCID: PMC6639324.
      Citations: 44     Fields:    Translation:Humans
    71. Farooqi A, Yang J, Sharin V, Ezhilarasan R, Danussi C, Alvarez C, Dharmaiah S, Irvin D, Huse J, Sulman EP. Identification of patient-derived glioblastoma stem cell (GSC) lines with the alternative lengthening of telomeres phenotype. Acta Neuropathol Commun. 2019 05 16; 7(1):76. PMID: 31097032; PMCID: PMC6521362.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    72. Ostrom Q, Bondy ML, Huse JT. Integrating germline and somatic genomic analysis to probe etiological mechanism in malignant glioma. Oncotarget. 2019 May 03; 10(33):3086-3087. PMID: 31139320; PMCID: PMC6517101.
      Citations:    Fields:    
    73. Ballester LY, Moghadamtousi SZ, Leeds NE, Huse JT, Fuller GN. Coexisting FGFR3 p.K650T mutation in two FGFR3-TACC3 fusion glioma cases. Acta Neuropathol Commun. 2019 04 29; 7(1):63. PMID: 31036092; PMCID: PMC6487516.
      Citations: 6     Fields:    Translation:HumansCells
    74. Ostrom QT, Egan KM, Nabors LB, Gerke T, Thompson RC, Olson JJ, LaRocca R, Chowdhary S, Eckel-Passow JE, Armstrong G, Wiencke JK, Bernstein JL, Claus EB, Il'yasova D, Johansen C, Lachance DH, Lai RK, Merrell RT, Olson SH, Sadetzki S, Schildkraut JM, Shete S, Houlston RS, Jenkins RB, Wrensch MR, Amos CI, Huse JT, Barnholtz-Sloan JS, Bondy ML, Melin B. Glioma risk associated with extent of estimated European genetic ancestry in African Americans and Hispanics. Int J Cancer. 2020 02 01; 146(3):739-748. PMID: 30963577; PMCID: PMC6785354.
      Citations: 10     Fields:    Translation:Humans
    75. Wang Y, Yang J, Wild AT, Wu WH, Shah R, Danussi C, Riggins GJ, Kannan K, Sulman EP, Chan TA, Huse JT. G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma. Nat Commun. 2019 02 26; 10(1):943. PMID: 30808951; PMCID: PMC6391399.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    76. Fischer GM, Jalali A, Kircher DA, Lee WC, McQuade JL, Haydu LE, Joon AY, Reuben A, Carapeto FCL, Yang C, Srivastava A, Ambati CR, Sreekumar A, Hudgens CW, Knighton B, Deng W, Ferguson SD, Tawbi HA, Glitza IC, Gershenwald JE, Vashisht Gopal YN, Hwu P, Huse JT, Wargo JA, Futreal PA, Putluri N, Lazar AJ, DeBerardinis RJ, Marszalek JR, Zhang J, Holmen SL, Tetzlaff MT, Davies MA, de Macedo MP. Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases. Cancer Discov. 2019 05; 9(5):628-645. PMID: 30787016; PMCID: PMC6497554.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    77. Wen PY, Touat M, Alexander BM, Mellinghoff IK, Ramkissoon S, McCluskey CS, Pelton K, Haidar S, Basu SS, Gaffey SC, Brown LE, Martinez-Ledesma JE, Wu S, Kim J, Wei W, Park MA, Huse JT, Kuhn JG, Rinne ML, Colman H, Agar NYR, Omuro AM, DeAngelis LM, Gilbert MR, de Groot JF, Cloughesy TF, Chi AS, Roberts TM, Zhao JJ, Lee EQ, Nayak L, Heath JR, Horky LL, Batchelor TT, Beroukhim R, Chang SM, Ligon AH, Dunn IF, Koul D, Young GS, Prados MD, Reardon DA, Yung WKA, Ligon KL. Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial. J Clin Oncol. 2019 03 20; 37(9):741-750. PMID: 30715997; PMCID: PMC6553812.
      Citations: 42     Fields:    Translation:HumansCellsCTClinical Trials
    78. Hovinga KE, McCrea HJ, Brennan C, Huse J, Zheng J, Esquenazi Y, Panageas KS, Tabar V. EGFR amplification and classical subtype are associated with a poor response to bevacizumab in recurrent glioblastoma. J Neurooncol. 2019 Apr; 142(2):337-345. PMID: 30680510; PMCID: PMC6752204.
      Citations: 14     Fields:    Translation:Humans
    79. Mandel JJ, Youssef M, Nam J, Patel AJ, Jalali A, Ludmir EB, Liu D, Wu J, Armstrong G, Huse J, Bondy M, de Groot JF. Effect of health disparities on overall survival of patients with glioblastoma. J Neurooncol. 2019 Apr; 142(2):365-374. PMID: 30671709.
      Citations: 5     Fields:    Translation:Humans
    80. Majd NK, Metrus NR, Santos-Pinheiro F, Trevino CR, Fuller GN, Huse JT, Chung C, Ketonen L, Anderson MD, Penas-Prado M. RBM10 truncation in astroblastoma in a patient with history of mandibular ameloblastoma: A case report. Cancer Genet. 2019 02; 231-232:41-45. PMID: 30803556.
      Citations:    Fields:    Translation:Humans
    81. Yeboa DN, Yu JB, Liao E, Huse J, Penas-Prado M, Kann BH, Sulman E, Grosshans D, Contessa J. Differences in patterns of care and outcomes between grade II and grade III molecularly defined 1p19q co-deleted gliomas. Clin Transl Radiat Oncol. 2019 Feb; 15:46-52. PMID: 30656222; PMCID: PMC6329703.
      Citations: 3     
    82. Wei J, Marisetty A, Schrand B, Gabrusiewicz K, Hashimoto Y, Ott M, Grami Z, Kong LY, Ling X, Caruso H, Zhou S, Wang YA, Fuller GN, Huse J, Gilboa E, Kang N, Huang X, Verhaak R, Li S, Heimberger AB. Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target. J Clin Invest. 2019 01 02; 129(1):137-149. PMID: 30307407; PMCID: PMC6307970.
      Citations: 98     Fields:    Translation:HumansAnimalsCells
    83. Jacobs DI, Fukumura K, Bainbridge MN, Armstrong GN, Tsavachidis S, Gu X, Doddapaneni HV, Hu J, Jayaseelan JC, Muzny DM, Huse JT, Bondy ML. Elucidating the molecular pathogenesis of glioma: integrated germline and somatic profiling of a familial glioma case series. Neuro Oncol. 2018 11 12; 20(12):1625-1633. PMID: 30165405; PMCID: PMC6231201.
      Citations: 6     Fields:    Translation:Humans
    84. Koehler JW, Miller AD, Miller CR, Porter B, Aldape K, Beck J, Brat D, Cornax I, Corps K, Frank C, Giannini C, Horbinski C, Huse JT, O'Sullivan MG, Rissi DR, Mark Simpson R, Woolard K, Shih JH, Mazcko C, Gilbert MR, LeBlanc AK. A Revised Diagnostic Classification of Canine Glioma: Towards Validation of the Canine Glioma Patient as a Naturally Occurring Preclinical Model for Human Glioma. J Neuropathol Exp Neurol. 2018 11 01; 77(11):1039-1054. PMID: 30239918; PMCID: PMC6181180.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    85. Danussi C, Huse JT. Novel insights into the epigenetics of diffuse glioma. Mol Cell Oncol. 2018; 5(5):e1472055. PMID: 30263940; PMCID: PMC6154842.
      Citations: 1     
    86. Ballester LY, Glitza Oliva IC, Douse DY, Chen MM, Lan C, Haydu LE, Huse JT, Roy-Chowdhuri S, Luthra R, Wistuba II, Davies MA. Evaluating Circulating Tumor DNA From the Cerebrospinal Fluid of Patients With Melanoma and Leptomeningeal Disease. J Neuropathol Exp Neurol. 2018 07 01; 77(7):628-635. PMID: 29873738; PMCID: PMC6005029.
      Citations: 22     Fields:    Translation:Humans
    87. Eterovic AK, Maher OM, Chandra J, Chen K, Huse J, Zaky W. Metachronous Medulloblastoma in a Child With Successfully Treated Neuroblastoma: Case Report and Novel Findings of DNA Sequencing. J Natl Compr Canc Netw. 2018 06; 16(6):683-691. PMID: 29891519.
      Citations: 1     Fields:    Translation:Humans
    88. Ferguson SD, Zhou S, Huse JT, de Groot JF, Xiu J, Subramaniam DS, Mehta S, Gatalica Z, Swensen J, Sanai N, Spetzler D, Heimberger AB. Targetable Gene Fusions Associate With the IDH Wild-Type Astrocytic Lineage in Adult Gliomas. J Neuropathol Exp Neurol. 2018 06 01; 77(6):437-442. PMID: 29718398; PMCID: PMC5961205.
      Citations: 22     Fields:    Translation:HumansCells
    89. Everson RG, Hashimoto Y, Freeman JL, Hodges TR, Huse J, Zhou S, Xiu J, Spetzler D, Sanai N, Kim L, Kesari S, Brenner A, De Monte F, Heimberger A, Raza SM. Multiplatform profiling of meningioma provides molecular insight and prioritization of drug targets for rational clinical trial design. J Neurooncol. 2018 Sep; 139(2):469-478. PMID: 29846894.
      Citations: 7     Fields:    Translation:Humans
    90. Oldrini B, Marques C, Matia V, Torres-Ruiz R, Rodriguez-Perales S, Huse JT, Squatrito M, Curiel-Garc?a ?, Ulu?kan ?, Gra?a-Castro O. Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling. Nat Commun. 2018 Apr 13; 9(1):1466. PMID: 29654229; PMCID: PMC5899147.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    91. Ballester LY, Penas-Prado M, Leeds NE, Huse JT, Fuller GN. FGFR1 tyrosine kinase domain duplication in pilocytic astrocytoma with anaplasia. Cold Spring Harb Mol Case Stud. 2018 04; 4(2). PMID: 29610389; PMCID: PMC5880259.
      Citations: 7     Fields:    Translation:HumansCells
    92. Danussi C, Bose P, Parthasarathy PT, Silberman PC, Van Arnam JS, Vitucci M, Tang OY, Heguy A, Wang Y, Chan TA, Riggins GJ, Sulman EP, Lang FF, Creighton CJ, Deneen B, Miller CR, Picketts DJ, Kannan K, Huse JT. Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling. Nat Commun. 2018 03 13; 9(1):1057. PMID: 29535300; PMCID: PMC5849741.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    93. Gabrusiewicz K, Li X, Wei J, Hashimoto Y, Marisetty AL, Ott M, Wang F, Hawke D, Yu J, Healy LM, Hossain A, Akers JC, Maiti SN, Yamashita S, Shimizu Y, Dunner K, Zal MA, Burks JK, Gumin J, Nwajei F, Rezavanian A, Zhou S, Rao G, Sawaya R, Fuller GN, Huse JT, Antel JP, Li S, Cooper L, Sulman EP, Chen C, Geula C, Kalluri R, Zal T, Heimberger AB. Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes. Oncoimmunology. 2018; 7(4):e1412909. PMID: 29632728; PMCID: PMC5889290.
      Citations: 122     Fields:    
    94. Wen PY, Huse JT. 2016 World Health Organization Classification of Central Nervous System Tumors. Continuum (Minneap Minn). 2017 12; 23(6, Neuro-oncology):1531-1547. PMID: 29200109.
      Citations: 52     Fields:    Translation:Humans
    95. Turcan S, Makarov V, Taranda J, Wang Y, Fabius AWM, Wu W, Zheng Y, El-Amine N, Haddock S, Nanjangud G, LeKaye HC, Brennan C, Cross J, Huse JT, Kelleher NL, Osten P, Thompson CB, Chan TA. Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence. Nat Genet. 2018 01; 50(1):62-72. PMID: 29180699; PMCID: PMC5769471.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    96. Thomas AA, Abrey LE, Terziev R, Raizer J, Martinez NL, Forsyth P, Paleologos N, Matasar M, Sauter CS, Moskowitz C, Nimer SD, DeAngelis LM, Kaley T, Grimm S, Louis DN, Cairncross JG, Panageas KS, Briggs S, Faivre G, Mohile NA, Mehta J, Jonsson P, Chakravarty D, Gao J, Schultz N, Brennan CW, Huse JT, Omuro A. Multicenter phase II study of temozolomide and myeloablative chemotherapy with autologous stem cell transplant for newly diagnosed anaplastic oligodendroglioma. Neuro Oncol. 2017 Oct 01; 19(10):1380-1390. PMID: 28472509; PMCID: PMC5596171.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    97. Chakravarty D, Pedraza AM, Cotari J, Liu AH, Punko D, Kokroo A, Huse JT, Altan-Bonnet G, Brennan CW. EGFR and PDGFRA co-expression and heterodimerization in glioblastoma tumor sphere lines. Sci Rep. 2017 08 22; 7(1):9043. PMID: 28831081; PMCID: PMC5567352.
      Citations: 19     Fields:    Translation:HumansCells
    98. Hodges TR, Ott M, Xiu J, Gatalica Z, Swensen J, Zhou S, Huse JT, de Groot J, Li S, Overwijk WW, Spetzler D, Heimberger AB. Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapy. Neuro Oncol. 2017 Aug 01; 19(8):1047-1057. PMID: 28371827; PMCID: PMC5570198.
      Citations: 165     Fields:    Translation:HumansCells
    99. Yan D, Kowal J, Akkari L, Schuhmacher AJ, Huse JT, West BL, Joyce JA. Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas. Oncogene. 2017 10 26; 36(43):6049-6058. PMID: 28759044; PMCID: PMC5666319.
      Citations:    
    100. Lee SH, Kim JS, Zheng S, Huse JT, Bae JS, Lee JW, Yoo KH, Koo HH, Kyung S, Park WY, Sung KW. ARID1B alterations identify aggressive tumors in neuroblastoma. Oncotarget. 2017 Jul 11; 8(28):45943-45950. PMID: 28521285; PMCID: PMC5542239.
      Citations: 10     Fields:    Translation:Humans
    101. Grommes C, Pastore A, Palaskas N, Tang SS, Campos C, Schartz D, Codega P, Nichol D, Clark O, Hsieh WY, Rohle D, Rosenblum M, Tabar VS, Brennan CW, Gavrilovic IT, Kaley TJ, Nolan CP, Omuro A, Pentsova E, Thomas AA, Tsyvkin E, Noy A, Palomba ML, Hamlin P, Sauter CS, Moskowitz CH, Wolfe J, Dogan A, Won M, Glass J, Peak S, Lallana EC, Hatzoglou V, Reiner AS, Gutin PH, Huse JT, Panageas KS, Graeber TG, Schultz N, DeAngelis LM, Mellinghoff IK, Viale A. Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma. Cancer Discov. 2017 09; 7(9):1018-1029. PMID: 28619981; PMCID: PMC5581705.
      Citations: 103     Fields:    Translation:HumansCTClinical Trials
    102. Becher OJ, Millard NE, Modak S, Kushner BH, Haque S, Spasojevic I, Trippett TM, Gilheeney SW, Khakoo Y, Lyden DC, De Braganca KC, Kolesar JM, Huse JT, Kramer K, Cheung NV, Dunkel IJ. A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors. PLoS One. 2017; 12(6):e0178593. PMID: 28582410; PMCID: PMC5459446.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    103. Ballester LY, Huse JT, Tang G, Fuller GN. Molecular classification of adult diffuse gliomas: conflicting IDH1/IDH2, ATRX, and 1p/19q results. Hum Pathol. 2017 11; 69:15-22. PMID: 28549927.
      Citations: 12     Fields:    Translation:HumansCells
    104. Huang Y, Rajappa P, Hu W, Hoffman C, Cisse B, Kim JH, Gorge E, Yanowitch R, Cope W, Vartanian E, Xu R, Zhang T, Pisapia D, Xiang J, Huse J, Matei I, Peinado H, Bromberg J, Holland E, Ding BS, Rafii S, Lyden D, Greenfield J. A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma. J Clin Invest. 2017 May 01; 127(5):1826-1838. PMID: 28394259; PMCID: PMC5409793.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    105. Becher OJ, Gilheeney SW, Khakoo Y, Lyden DC, Haque S, De Braganca KC, Kolesar JM, Huse JT, Modak S, Wexler LH, Kramer K, Spasojevic I, Dunkel IJ. A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors. Pediatr Blood Cancer. 2017 Jul; 64(7). PMID: 28035748.
      Citations: 26     Fields:    Translation:HumansCTClinical Trials
    106. Rajappa P, Cobb WS, Vartanian E, Huang Y, Daly L, Hoffman C, Zhang J, Shen B, Yanowitch R, Garg K, Cisse B, Haddock S, Huse J, Pisapia DJ, Chan TA, Lyden DC, Bromberg JF, Greenfield JP. Malignant Astrocytic Tumor Progression Potentiated by JAK-mediated Recruitment of Myeloid Cells. Clin Cancer Res. 2017 Jun 15; 23(12):3109-3119. PMID: 28039266; PMCID: PMC5769921.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    107. Lin X, Lee M, Buck O, Woo KM, Zhang Z, Hatzoglou V, Omuro A, Arevalo-Perez J, Thomas AA, Huse J, Peck K, Holodny AI, Young RJ. Diagnostic Accuracy of T1-Weighted Dynamic Contrast-Enhanced-MRI and DWI-ADC for Differentiation of Glioblastoma and Primary CNS Lymphoma. AJNR Am J Neuroradiol. 2017 Mar; 38(3):485-491. PMID: 27932505; PMCID: PMC5352508.
      Citations:    
    108. Huse JT, Snuderl M, Jones DT, Brathwaite CD, Altman N, Lavi E, Saffery R, Sexton-Oates A, Blumcke I, Capper D, Karajannis MA, Benayed R, Chavez L, Thomas C, Serrano J, Borsu L, Ladanyi M, Rosenblum MK. Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway. Acta Neuropathol. 2017 03; 133(3):417-429. PMID: 27812792; PMCID: PMC5325850.
      Citations: 56     Fields:    Translation:HumansCells
    109. Huse JT. Establishing a Robust Molecular Taxonomy for Diffuse Gliomas of Adulthood. Surg Pathol Clin. 2016 Sep; 9(3):379-90. PMID: 27523967.
      Citations: 1     Fields:    Translation:HumansCells
    110. Oktay Y, Akyerli CB, Erdemgil Y, Durasi IM, Henegariu OI, Nanni EP, Selevsek N, Grossmann J, Erson-Omay EZ, Bai H, Gupta M, Lee W, Turcan S, Huse JT, Sav MA, Flanagan A, Sezerman OU, Yakicier MC, Pamir MN, ?lgen E, Can ?, Y?ksel S, ?zpinar A, G?nel M, ?zduman K. IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation. Sci Rep. 2016 06 10; 6:27569. PMID: 27282637; PMCID: PMC4901315.
      Citations: 12     Fields:    Translation:Humans
    111. Quail DF, Bowman RL, Akkari L, Quick ML, Schuhmacher AJ, Huse JT, Holland EC, Sutton JC, Joyce JA. The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas. Science. 2016 May 20; 352(6288):aad3018. PMID: 27199435; PMCID: PMC5450629.
      Citations: 242     Fields:    Translation:HumansAnimalsCells
    112. Roy DM, Walsh LA, Desrichard A, Huse JT, Wu W, Gao J, Bose P, Lee W, Chan TA. Integrated Genomics for Pinpointing Survival Loci within Arm-Level Somatic Copy Number Alterations. Cancer Cell. 2016 05 09; 29(5):737-750. PMID: 27165745; PMCID: PMC4864611.
      Citations: 22     Fields:    Translation:HumansCells
    113. Ceccarelli M, Salama SR, Murray BA, Morozova O, Newton Y, Radenbaugh A, Pagnotta SM, Anjum S, Wang J, Zoppoli P, Rao AA, Grifford M, Cherniack AD, Zhang H, Poisson L, Mikkelsen T, Lau CC, Rabadan R, Huse J, Brat DJ, Lehman NL, Barnholtz-Sloan JS, Meyerson M, Beroukhim R, Cooper L, Wrensch M, Haussler D, Aldape KD, Laird PW, Gutmann DH, TCGA Research Network, Iavarone A, Barthel FP, Malta TM, Sabedot TS, Manyam G, Ling S, Carlotti CG, Tirapelli DP, Rao A, Yung WK, Zheng S, Hess K, Rao G, Akbani R, Noushmehr H, Verhaak RG. Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma. Cell. 2016 Jan 28; 164(3):550-63. PMID: 26824661; PMCID: PMC4754110.
      Citations: 859     Fields:    Translation:HumansCells
    114. Butowski N, Colman H, De Groot JF, Omuro AM, Nayak L, Wen PY, Cloughesy TF, Marimuthu A, Haidar S, Perry A, Huse J, Phillips J, West BL, Nolop KB, Hsu HH, Ligon KL, Molinaro AM, Prados M. Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study. Neuro Oncol. 2016 Apr; 18(4):557-64. PMID: 26449250; PMCID: PMC4799682.
      Citations: 215     Fields:    Translation:HumansCTClinical Trials
    115. Eckel-Passow JE, Lachance DH, Molinaro AM, Walsh KM, Decker PA, Sicotte H, Pekmezci M, Rice T, Kosel ML, Smirnov IV, Sarkar G, Caron AA, Kollmeyer TM, Praska CE, Chada AR, Halder C, Hansen HM, McCoy LS, Bracci PM, Marshall R, Zheng S, Reis GF, Pico AR, O'Neill BP, Buckner JC, Giannini C, Huse JT, Perry A, Tihan T, Berger MS, Chang SM, Prados MD, Wiemels J, Wiencke JK, Wrensch MR, Jenkins RB. Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors. N Engl J Med. 2015 Jun 25; 372(26):2499-508. PMID: 26061753; PMCID: PMC4489704.
      Citations: 764     Fields:    Translation:HumansCells
    116. Cancer Genome Atlas Research Network, Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, Akbani R, Huse JT, Ciriello G, Poisson LM, Barnholtz-Sloan JS, Berger MS, Brennan C, Colen RR, Colman H, Flanders AE, Giannini C, Grifford M, Iavarone A, Jain R, Joseph I, Kim J, Kasaian K, Mikkelsen T, Murray BA, O'Neill BP, Pachter L, Parsons DW, Sougnez C, Sulman EP, Vandenberg SR, Van Meir EG, von Deimling A, Zhang H, Crain D, Lau K, Mallery D, Morris S, Paulauskis J, Penny R, Shelton T, Sherman M, Yena P, Black A, Bowen J, Dicostanzo K, Gastier-Foster J, Leraas KM, Lichtenberg TM, Pierson CR, Ramirez NC, Taylor C, Weaver S, Wise L, Zmuda E, Davidsen T, Demchok JA, Eley G, Ferguson ML, Hutter CM, Mills Shaw KR, Ozenberger BA, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Ayala B, Baboud J, Chudamani S, Jensen MA, Liu J, Pihl T, Raman R, Wan Y, Wu Y, Ally A, Auman JT, Balasundaram M, Balu S, Baylin SB, Beroukhim R, Bootwalla MS, Bowlby R, Bristow CA, Brooks D, Butterfield Y, Carlsen R, Carter S, Chin L, Chu A, Chuah E, Cibulskis K, Clarke A, Coetzee SG, Dhalla N, Fennell T, Fisher S, Gabriel S, Getz G, Gibbs R, Guin R, Hadjipanayis A, Hayes DN, Hinoue T, Hoadley K, Holt RA, Hoyle AP, Jefferys SR, Jones S, Jones CD, Kucherlapati R, Lai PH, Lander E, Lee S, Lichtenstein L, Ma Y, Maglinte DT, Mahadeshwar HS, Marra MA, Mayo M, Meng S, Meyerson ML, Mieczkowski PA, Moore RA, Mose LE, Mungall AJ, Pantazi A, Parfenov M, Park PJ, Parker JS, Perou CM, Protopopov A, Ren X, Roach J, Schein J, Schumacher SE, Seidman JG, Seth S, Shen H, Simons JV, Sipahimalani P, Soloway MG, Song X, Sun H, Tabak B, Tam A, Tan D, Tang J, Thiessen N, Triche T, Van Den Berg DJ, Veluvolu U, Waring S, Weisenberger DJ, Wilkerson MD, Wong T, Wu J, Xi L, Xu AW, Yang L, Zack TI, Zhang J, Aksoy BA, Arachchi H, Benz C, Bernard B, Carlin D, Cho J, DiCara D, Frazer S, Fuller GN, Gao J, Gehlenborg N, Haussler D, Heiman DI, Iype L, Jacobsen A, Ju Z, Katzman S, Kim H, Knijnenburg T, Kreisberg RB, Lawrence MS, Lee W, Leinonen K, Lin P, Ling S, Liu W, Liu Y, Liu Y, Lu Y, Mills G, Ng S, Noble MS, Paull E, Rao A, Reynolds S, Saksena G, Sanborn Z, Sander C, Schultz N, Senbabaoglu Y, Shen R, Shmulevich I, Sinha R, Stuart J, Sumer SO, Sun Y, Tasman N, Taylor BS, Voet D, Weinhold N, Weinstein JN, Yang D, Yoshihara K, Zheng S, Zhang W, Zou L, Abel T, Sadeghi S, Cohen ML, Eschbacher J, Hattab EM, Raghunathan A, Schniederjan MJ, Aziz D, Barnett G, Barrett W, Bigner DD, Boice L, Brewer C, Calatozzolo C, Campos B, Carlotti CG, Chan TA, Cuppini L, Curley E, Cuzzubbo S, Devine K, DiMeco F, Duell R, Elder JB, Fehrenbach A, Finocchiaro G, Friedman W, Fulop J, Gardner J, Hermes B, Herold-Mende C, Jungk C, Kendler A, Lehman NL, Lipp E, Liu O, Mandt R, McGraw M, Mclendon R, McPherson C, Neder L, Nguyen P, Noss A, Nunziata R, Ostrom QT, Palmer C, Perin A, Pollo B, Potapov A, Potapova O, Rathmell WK, Rotin D, Scarpace L, Schilero C, Senecal K, Shimmel K, Shurkhay V, Sifri S, Singh R, Sloan AE, Smolenski K, Staugaitis SM, Steele R, Thorne L, Tirapelli DP, Unterberg A, Vallurupalli M, Wang Y, Warnick R, Williams F, et al. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med. 2015 Jun 25; 372(26):2481-98. PMID: 26061751; PMCID: PMC4530011.
      Citations: 1192     Fields:    Translation:HumansCells
    117. Nayak L, Panageas KS, Reiner AS, Huse JT, Pentsova E, Braunthal SG, Abrey LE, DeAngelis LM, Lassman AB. Radiotherapy and temozolomide for anaplastic astrocytic gliomas. J Neurooncol. 2015 May; 123(1):129-34. PMID: 25920709; PMCID: PMC4606458.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    118. Lee EQ, Kaley TJ, Duda DG, Schiff D, Lassman AB, Wong ET, Mikkelsen T, Purow BW, Muzikansky A, Ancukiewicz M, Huse JT, Ramkissoon S, Drappatz J, Norden AD, Beroukhim R, Weiss SE, Alexander BM, McCluskey CS, Gerard M, Smith KH, Jain RK, Batchelor TT, Ligon KL, Wen PY. A Multicenter, Phase II, Randomized, Noncomparative Clinical Trial of Radiation and Temozolomide with or without Vandetanib in Newly Diagnosed Glioblastoma Patients. Clin Cancer Res. 2015 Aug 15; 21(16):3610-8. PMID: 25910950; PMCID: PMC4790106.
      Citations: 36     Fields:    Translation:HumansCTClinical Trials
    119. Huse JT, Rosenblum MK. The Emerging Molecular Foundations of Pediatric Brain Tumors. J Child Neurol. 2015 Nov; 30(13):1838-50. PMID: 25873586.
      Citations: 5     Fields:    Translation:Humans
    120. Cope WP, Vartanian ED, Reiner AS, Kellen R, Ogilvie SQ, Huse JT, Gutin PH, Moliterno J. Survival in patients treated for anaplastic meningioma. J Neurosurg. 2015 Jul; 123(1):23-30. PMID: 25859807.
      Citations: 28     Fields:    Translation:Humans
    121. Kiess AP, Wolchok JD, Barker CA, Postow MA, Tabar V, Huse JT, Chan TA, Yamada Y, Beal K. Stereotactic radiosurgery for melanoma brain metastases in patients receiving ipilimumab: safety profile and efficacy of combined treatment. Int J Radiat Oncol Biol Phys. 2015 Jun 01; 92(2):368-75. PMID: 25754629; PMCID: PMC4955924.
      Citations: 153     Fields:    Translation:Humans
    122. Huse JT, Venneti S. The evolving molecular genetics of low-grade glioma. Adv Anat Pathol. 2015 Mar; 22(2):94-101. PMID: 25664944; PMCID: PMC4667550.
      Citations: 35     Fields:    Translation:Humans
    123. Hechtman JF, Sadowska J, Huse JT, Borsu L, Yaeger R, Shia J, Vakiani E, Ladanyi M, Arcila ME. AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants. Mol Cancer Res. 2015 Jun; 13(6):1003-8. PMID: 25714871; PMCID: PMC4978128.
      Citations: 14     Fields:    Translation:HumansCells
    124. Huse JT. TERT promoter mutation designates biologically aggressive primary glioblastoma. Neuro Oncol. 2015 Jan; 17(1):5-6. PMID: 25452394; PMCID: PMC4483057.
      Citations: 3     Fields:    Translation:Humans
    125. Huse JT, Aldape KD. The evolving role of molecular markers in the diagnosis and management of diffuse glioma. Clin Cancer Res. 2014 Nov 15; 20(22):5601-11. PMID: 25398843.
      Citations: 28     Fields:    Translation:HumansCells
    126. Huse JT, Aldape K. CMV and glioma--are we there yet? Neuro Oncol. 2014 Nov; 16(11):1433-4. PMID: 25326550; PMCID: PMC4201080.
      Citations: 4     Fields:    Translation:HumansCells
    127. Huse JT, Diamond EL, Wang L, Rosenblum MK. Mixed glioma with molecular features of composite oligodendroglioma and astrocytoma: a true "oligoastrocytoma"? Acta Neuropathol. 2015 Jan; 129(1):151-3. PMID: 25359109.
      Citations: 32     Fields:    Translation:Humans
    128. Oricchio E, Papapetrou EP, Lafaille F, Ganat YM, Kriks S, Ortega-Molina A, Mark WH, Teruya-Feldstein J, Huse JT, Reuter V, Sadelain M, Studer L, Wendel HG. A cell engineering strategy to enhance the safety of stem cell therapies. Cell Rep. 2014 Sep 25; 8(6):1677-1685. PMID: 25242333; PMCID: PMC4177332.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    129. Alexander BM, Galanis E, Yung WK, Ballman KV, Boyett JM, Cloughesy TF, Degroot JF, Huse JT, Mann B, Mason W, Mellinghoff IK, Mikkelsen T, Mischel PS, O'Neill BP, Prados MD, Sarkaria JN, Tawab-Amiri A, Trippa L, Ye X, Ligon KL, Berry DA, Wen PY. Brain Malignancy Steering Committee clinical trials planning workshop: report from the Targeted Therapies Working Group. Neuro Oncol. 2015 Feb; 17(2):180-8. PMID: 25165194; PMCID: PMC4288520.
      Citations: 11     Fields:    Translation:Humans
    130. Ozawa T, Riester M, Cheng YK, Huse JT, Squatrito M, Helmy K, Charles N, Michor F, Holland EC. Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma. Cancer Cell. 2014 Aug 11; 26(2):288-300. PMID: 25117714; PMCID: PMC4143139.
      Citations: 191     Fields:    Translation:HumansAnimalsCells
    131. Omuro A, Beal K, Gutin P, Karimi S, Correa DD, Kaley TJ, DeAngelis LM, Chan TA, Gavrilovic IT, Nolan C, Hormigo A, Lassman AB, Mellinghoff I, Grommes C, Reiner AS, Panageas KS, Baser RE, Tabar V, Pentsova E, Sanchez J, Barradas-Panchal R, Zhang J, Faivre G, Brennan CW, Abrey LE, Huse JT. Phase II study of bevacizumab, temozolomide, and hypofractionated stereotactic radiotherapy for newly diagnosed glioblastoma. Clin Cancer Res. 2014 Oct 01; 20(19):5023-31. PMID: 25107913; PMCID: PMC4523080.
      Citations: 50     Fields:    Translation:HumansCTClinical Trials
    132. Ortiz B, Fabius AW, Wu WH, Pedraza A, Brennan CW, Schultz N, Pitter KL, Bromberg JF, Huse JT, Holland EC, Chan TA. Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):8149-54. PMID: 24843164; PMCID: PMC4050622.
      Citations: 44     Fields:    Translation:HumansAnimals
    133. Gerber NK, Goenka A, Turcan S, Reyngold M, Makarov V, Kannan K, Beal K, Omuro A, Yamada Y, Gutin P, Brennan CW, Huse JT, Chan TA. Transcriptional diversity of long-term glioblastoma survivors. Neuro Oncol. 2014 Sep; 16(9):1186-95. PMID: 24662514; PMCID: PMC4136896.
      Citations: 35     Fields:    Translation:HumansCells
    134. Pietras A, Katz AM, Wee B, Halliday JJ, Pitter KL, Werbeck JL, Amankulor NM, Huse JT, Holland EC, Ekstr?m EJ. Osteopontin-CD44 signaling in the glioma perivascular niche enhances cancer stem cell phenotypes and promotes aggressive tumor growth. Cell Stem Cell. 2014 Mar 06; 14(3):357-69. PMID: 24607407; PMCID: PMC3999042.
      Citations: 229     Fields:    Translation:HumansAnimalsCells
    135. Valiente M, Obenauf AC, Jin X, Chen Q, Zhang XH, Lee DJ, Chaft JE, Kris MG, Huse JT, Brogi E, Massagu? J. Serpins promote cancer cell survival and vascular co-option in brain metastasis. Cell. 2014 Feb 27; 156(5):1002-16. PMID: 24581498; PMCID: PMC3988473.
      Citations: 330     Fields:    Translation:HumansAnimalsCells
    136. Cairncross JG, Wang M, Jenkins RB, Shaw EG, Giannini C, Brachman DG, Buckner JC, Fink KL, Souhami L, Laperriere NJ, Huse JT, Mehta MP, Curran WJ. Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH. J Clin Oncol. 2014 Mar 10; 32(8):783-90. PMID: 24516018; PMCID: PMC3940537.
      Citations: 161     Fields:    Translation:Humans
    137. Gupta A, Young RJ, Shah AD, Schweitzer AD, Graber JJ, Shi W, Zhang Z, Huse J, Omuro AM. Pretreatment Dynamic Susceptibility Contrast MRI Perfusion in Glioblastoma: Prediction of EGFR Gene Amplification. Clin Neuroradiol. 2015 Jun; 25(2):143-50. PMID: 24474262; PMCID: PMC4712066.
      Citations:    
    138. Huang Y, Hoffman C, Rajappa P, Kim JH, Hu W, Huse J, Tang Z, Li X, Weksler B, Bromberg J, Lyden DC, Greenfield JP. Oligodendrocyte progenitor cells promote neovascularization in glioma by disrupting the blood-brain barrier. Cancer Res. 2014 Feb 15; 74(4):1011-21. PMID: 24371228.
      Citations: 25     Fields:    Translation:AnimalsCells
    139. Huse JT, Wallace M, Aldape KD, Berger MS, Bettegowda C, Brat DJ, Cahill DP, Cloughesy T, Haas-Kogan DA, Marra M, Miller CR, Nelson SJ, Salama SR, Soffietti R, Wen PY, Yip S, Yen K, Costello JF, Chang S. Where are we now? And where are we going? A report from the Accelerate Brain Cancer Cure (ABC2) low-grade glioma research workshop. Neuro Oncol. 2014 Jan; 16(2):173-8. PMID: 24305708; PMCID: PMC3895389.
      Citations: 17     Fields:    Translation:Humans
    140. Kastenhuber ER, Huse JT, Berman SH, Pedraza A, Zhang J, Suehara Y, Viale A, Cavatore M, Heguy A, Szerlip N, Ladanyi M, Brennan CW. Quantitative assessment of intragenic receptor tyrosine kinase deletions in primary glioblastomas: their prevalence and molecular correlates. Acta Neuropathol. 2014 May; 127(5):747-59. PMID: 24292886; PMCID: PMC3984672.
      Citations: 18     Fields:    
    141. Huse JT, Aldape KD. The molecular landscape of diffuse glioma and prospects for biomarker development. Expert Opin Med Diagn. 2013 Nov; 7(6):573-87. PMID: 24161073.
      Citations: 7     Fields:    Translation:Humans
    142. Aldaz B, Sagardoy A, Nogueira L, Guruceaga E, Grande L, Huse JT, Aznar MA, Alonso MM, Fernandez-Luna JL, Martinez-Climent JA, Malumbres R, D?ez-Valle R, Tejada-Sol?s S. Involvement of miRNAs in the differentiation of human glioblastoma multiforme stem-like cells. PLoS One. 2013; 8(10):e77098. PMID: 24155920; PMCID: PMC3796557.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    143. Jacobsen A, Silber J, Harinath G, Huse JT, Schultz N, Sander C. Analysis of microRNA-target interactions across diverse cancer types. Nat Struct Mol Biol. 2013 Nov; 20(11):1325-32. PMID: 24096364; PMCID: PMC3982325.
      Citations: 99     Fields:    Translation:HumansCells
    144. Turcan S, Fabius AW, Borodovsky A, Pedraza A, Brennan C, Huse J, Viale A, Riggins GJ, Chan TA. Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine. Oncotarget. 2013 Oct; 4(10):1729-36. PMID: 24077826; PMCID: PMC3858559.
      Citations: 109     Fields:    Translation:HumansAnimalsCells
    145. Pyonteck SM, Akkari L, Schuhmacher AJ, Bowman RL, Sevenich L, Quail DF, Olson OC, Quick ML, Huse JT, Teijeiro V, Setty M, Leslie CS, Oei Y, Pedraza A, Zhang J, Brennan CW, Sutton JC, Holland EC, Daniel D, Joyce JA. CSF-1R inhibition alters macrophage polarization and blocks glioma progression. Nat Med. 2013 Oct; 19(10):1264-72. PMID: 24056773; PMCID: PMC3840724.
      Citations: 905     Fields:    Translation:AnimalsCells
    146. Young RJ, Gupta A, Shah AD, Graber JJ, Schweitzer AD, Prager A, Shi W, Zhang Z, Huse J, Omuro AM. Potential role of preoperative conventional MRI including diffusion measurements in assessing epidermal growth factor receptor gene amplification status in patients with glioblastoma. AJNR Am J Neuroradiol. 2013 Dec; 34(12):2271-7. PMID: 23811973; PMCID: PMC4712068.
      Citations:    
    147. Ho AS, Kannan K, Roy DM, Morris LG, Ganly I, Katabi N, Ramaswami D, Walsh LA, Eng S, Huse JT, Zhang J, Dolgalev I, Huberman K, Heguy A, Viale A, Drobnjak M, Leversha MA, Rice CE, Singh B, Iyer NG, Leemans CR, Bloemena E, Ferris RL, Seethala RR, Gross BE, Liang Y, Sinha R, Peng L, Raphael BJ, Turcan S, Gong Y, Schultz N, Kim S, Chiosea S, Shah JP, Sander C, Lee W, Chan TA. The mutational landscape of adenoid cystic carcinoma. Nat Genet. 2013 Jul; 45(7):791-8. PMID: 23685749; PMCID: PMC3708595.
      Citations: 172     Fields:    Translation:HumansAnimalsCells
    148. Venneti S, Felicella MM, Coyne T, Phillips JJ, Gorovets D, Huse JT, Kofler J, Lu C, Tihan T, Sullivan LM, Santi M, Judkins AR, Perry A, Thompson CB. Histone 3 lysine 9 trimethylation is differentially associated with isocitrate dehydrogenase mutations in oligodendrogliomas and high-grade astrocytomas. J Neuropathol Exp Neurol. 2013 Apr; 72(4):298-306. PMID: 23481705; PMCID: PMC3615673.
      Citations: 33     Fields:    Translation:HumansCells
    149. Venneti S, Garimella MT, Sullivan LM, Martinez D, Huse JT, Heguy A, Santi M, Thompson CB, Judkins AR. Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas. Brain Pathol. 2013 Sep; 23(5):558-64. PMID: 23414300; PMCID: PMC3701028.
      Citations: 106     Fields:    Translation:HumansCells
    150. Huse JT, Edgar M, Halliday J, Mikolaenko I, Lavi E, Rosenblum MK. Multinodular and vacuolating neuronal tumors of the cerebrum: 10 cases of a distinctive seizure-associated lesion. Brain Pathol. 2013 Sep; 23(5):515-24. PMID: 23324039; PMCID: PMC8029170.
      Citations: 29     Fields:    Translation:Humans
    151. Kim JH, Huse JT, Huang Y, Lyden D, Greenfield JP. Molecular diagnostics in paediatric glial tumours. Lancet Oncol. 2013 Jan; 14(1):e19-27. PMID: 23276367.
      Citations: 6     Fields:    Translation:HumansCells
    152. Hatzoglou V, Patel GV, Morris MJ, Curtis K, Zhang Z, Shi W, Huse J, Rosenblum M, Holodny AI, Young RJ. Brain metastases from prostate cancer: an 11-year analysis in the MRI era with emphasis on imaging characteristics, incidence, and prognosis. J Neuroimaging. 2014 Mar-Apr; 24(2):161-6. PMID: 23279641; PMCID: PMC4724409.
      Citations: 26     Fields:    Translation:Humans
    153. Omuro A, Chan TA, Abrey LE, Khasraw M, Reiner AS, Kaley TJ, Deangelis LM, Lassman AB, Nolan CP, Gavrilovic IT, Hormigo A, Salvant C, Heguy A, Kaufman A, Huse JT, Panageas KS, Hottinger AF, Mellinghoff I. Phase II trial of continuous low-dose temozolomide for patients with recurrent malignant glioma. Neuro Oncol. 2013 Feb; 15(2):242-50. PMID: 23243055; PMCID: PMC3548585.
      Citations: 44     Fields:    Translation:HumansCTClinical Trials
    154. Binda E, Visioli A, Giani F, Lamorte G, Copetti M, Pitter KL, Huse JT, Cajola L, Zanetti N, DiMeco F, De Filippis L, Mangiola A, Maira G, Anile C, De Bonis P, Reynolds BA, Pasquale EB, Vescovi AL. The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas. Cancer Cell. 2012 Dec 11; 22(6):765-80. PMID: 23238013; PMCID: PMC3922047.
      Citations: 99     Fields:    Translation:HumansCells
    155. Bazzoli E, Pulvirenti T, Oberstadt MC, Perna F, Wee B, Schultz N, Huse JT, Fomchenko EI, Voza F, Tabar V, Brennan CW, DeAngelis LM, Nimer SD, Holland EC, Squatrito M. MEF promotes stemness in the pathogenesis of gliomas. Cell Stem Cell. 2012 Dec 07; 11(6):836-44. PMID: 23217424; PMCID: PMC3812924.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    156. Silber J, Hashizume R, Felix T, Hariono S, Yu M, Berger MS, Huse JT, VandenBerg SR, James CD, Hodgson JG, Gupta N. Expression of miR-124 inhibits growth of medulloblastoma cells. Neuro Oncol. 2013 Jan; 15(1):83-90. PMID: 23172372; PMCID: PMC3534424.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    157. Huse JT, Holland E, DeAngelis LM. Glioblastoma: molecular analysis and clinical implications. Annu Rev Med. 2013; 64:59-70. PMID: 23043492.
      Citations: 48     Fields:    Translation:HumansAnimals
    158. Kannan K, Inagaki A, Silber J, Gorovets D, Zhang J, Kastenhuber ER, Heguy A, Petrini JH, Chan TA, Huse JT. Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma. Oncotarget. 2012 Oct; 3(10):1194-203. PMID: 23104868; PMCID: PMC3717947.
      Citations: 118     Fields:    Translation:Humans
    159. Fischer C, Haque SS, Huse JT, Blochin E, Souweidane MM, Lis E, Khakoo Y. Extraneural ependymoma: distant bone, lung, liver, and lymph node metastases following bevacizumab. Pediatr Blood Cancer. 2013 Jan; 60(1):143-5. PMID: 22976578.
      Citations: 5     Fields:    Translation:Humans
    160. Shen R, Mo Q, Schultz N, Seshan VE, Olshen AB, Huse J, Ladanyi M, Sander C. Integrative subtype discovery in glioblastoma using iCluster. PLoS One. 2012; 7(4):e35236. PMID: 22539962; PMCID: PMC3335101.
      Citations: 92     Fields:    Translation:HumansCells
    161. Silber J, Jacobsen A, Ozawa T, Harinath G, Pedraza A, Sander C, Holland EC, Huse JT. miR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis. PLoS One. 2012; 7(3):e33844. PMID: 22479456; PMCID: PMC3313940.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    162. Gorovets D, Kannan K, Shen R, Kastenhuber ER, Islamdoust N, Campos C, Pentsova E, Heguy A, Jhanwar SC, Mellinghoff IK, Chan TA, Huse JT. IDH mutation and neuroglial developmental features define clinically distinct subclasses of lower grade diffuse astrocytic glioma. Clin Cancer Res. 2012 May 01; 18(9):2490-501. PMID: 22415316.
      Citations: 72     Fields:    Translation:HumansCells
    163. Turcan S, Rohle D, Goenka A, Walsh LA, Fang F, Yilmaz E, Campos C, Fabius AW, Lu C, Ward PS, Thompson CB, Kaufman A, Guryanova O, Levine R, Heguy A, Viale A, Morris LG, Huse JT, Mellinghoff IK, Chan TA. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature. 2012 Feb 15; 483(7390):479-83. PMID: 22343889; PMCID: PMC3351699.
      Citations: 875     Fields:    Translation:HumansCells
    164. Szerlip NJ, Pedraza A, Chakravarty D, Azim M, McGuire J, Fang Y, Ozawa T, Holland EC, Huse JT, Jhanwar S, Leversha MA, Mikkelsen T, Brennan CW. Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):3041-6. PMID: 22323597; PMCID: PMC3286976.
      Citations: 250     Fields:    Translation:Humans
    165. Setty M, Helmy K, Khan AA, Silber J, Arvey A, Neezen F, Agius P, Huse JT, Holland EC, Leslie CS. Inferring transcriptional and microRNA-mediated regulatory programs in glioblastoma. Mol Syst Biol. 2012; 8:605. PMID: 22929615; PMCID: PMC3435504.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    166. Morris LG, Taylor BS, Bivona TG, Gong Y, Eng S, Brennan CW, Kaufman A, Kastenhuber ER, Banuchi VE, Singh B, Heguy A, Viale A, Mellinghoff IK, Huse J, Ganly I, Chan TA. Genomic dissection of the epidermal growth factor receptor (EGFR)/PI3K pathway reveals frequent deletion of the EGFR phosphatase PTPRS in head and neck cancers. Proc Natl Acad Sci U S A. 2011 Nov 22; 108(47):19024-9. PMID: 22065749; PMCID: PMC3223475.
      Citations: 40     Fields:    Translation:HumansCells
    167. Litkowski P, Khakoo Y, Gilheeney S, Souweidane M, Huse J, Haque S, Young RJ. Hemangioma of the cavernous sinus in a child. Neurology. 2011 Oct 25; 77(17):1647-8. PMID: 22025460.
      Citations:    
    168. Pulvirenti T, Van Der Heijden M, Droms LA, Huse JT, Tabar V, Hall A. Dishevelled 2 signaling promotes self-renewal and tumorigenicity in human gliomas. Cancer Res. 2011 Dec 01; 71(23):7280-90. PMID: 21990322; PMCID: PMC3228897.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    169. Huse JT, Nafa K, Shukla N, Kastenhuber ER, Lavi E, Hedvat CV, Ladanyi M, Rosenblum MK. High frequency of IDH-1 mutation links glioneuronal tumors with neuropil-like islands to diffuse astrocytomas. Acta Neuropathol. 2011 Sep; 122(3):367-9. PMID: 21755347; PMCID: PMC3170121.
      Citations: 6     Fields:    Translation:HumansCells
    170. Fomchenko EI, Dougherty JD, Helmy KY, Katz AM, Pietras A, Brennan C, Huse JT, Milosevic A, Holland EC. Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression. PLoS One. 2011; 6(7):e20605. PMID: 21754979; PMCID: PMC3130733.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    171. Palaskas N, Larson SM, Schultz N, Komisopoulou E, Wong J, Rohle D, Campos C, Yannuzzi N, Osborne JR, Linkov I, Kastenhuber ER, Taschereau R, Plaisier SB, Tran C, Heguy A, Wu H, Sander C, Phelps ME, Brennan C, Port E, Huse JT, Graeber TG, Mellinghoff IK. 18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers. Cancer Res. 2011 Aug 01; 71(15):5164-74. PMID: 21646475; PMCID: PMC3148325.
      Citations: 75     Fields:    Translation:HumansCells
    172. Huse JT, Phillips HS, Brennan CW. Molecular subclassification of diffuse gliomas: seeing order in the chaos. Glia. 2011 Aug; 59(8):1190-9. PMID: 21446051.
      Citations: 123     Fields:    Translation:HumansAnimals
    173. Squatrito M, Brennan CW, Helmy K, Huse JT, Petrini JH, Holland EC. Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas. Cancer Cell. 2010 Dec 14; 18(6):619-29. PMID: 21156285; PMCID: PMC3818087.
      Citations: 112     Fields:    Translation:HumansAnimalsCells
    174. Ozawa T, Brennan CW, Wang L, Squatrito M, Sasayama T, Nakada M, Huse JT, Pedraza A, Utsuki S, Yasui Y, Tandon A, Fomchenko EI, Oka H, Levine RL, Fujii K, Ladanyi M, Holland EC. PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas. Genes Dev. 2010 Oct 01; 24(19):2205-18. PMID: 20889717; PMCID: PMC2947772.
      Citations: 106     Fields:    Translation:HumansCells
    175. Ney DE, Huse JT, Dunkel IJ, Steinherz PG, Haque S, Khakoo Y. Intraventricular meningioma after cranial irradiation for childhood leukemia. J Child Neurol. 2010 Oct; 25(10):1292-5. PMID: 20207611.
      Citations: 2     Fields:    Translation:Humans
    176. Becher OJ, Hambardzumyan D, Walker TR, Helmy K, Nazarian J, Albrecht S, Hiner RL, Gall S, Huse JT, Jabado N, MacDonald TJ, Holland EC. Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma. Cancer Res. 2010 Mar 15; 70(6):2548-57. PMID: 20197468; PMCID: PMC3831613.
      Citations: 92     Fields:    Translation:Animals
    177. Bleau AM, Huse JT, Holland EC. The ABCG2 resistance network of glioblastoma. Cell Cycle. 2009 Sep 15; 8(18):2936-44. PMID: 19713741.
      Citations: 60     Fields:    Translation:HumansCells
    178. Huse JT, Brennan C, Hambardzumyan D, Wee B, Pena J, Rouhanifard SH, Sohn-Lee C, le Sage C, Agami R, Tuschl T, Holland EC. The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo. Genes Dev. 2009 Jun 01; 23(11):1327-37. PMID: 19487573; PMCID: PMC2701585.
      Citations: 271     Fields:    Translation:AnimalsCells
    179. Bleau AM, Hambardzumyan D, Ozawa T, Fomchenko EI, Huse JT, Brennan CW, Holland EC. PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell. 2009 Mar 06; 4(3):226-35. PMID: 19265662; PMCID: PMC3688060.
      Citations: 368     Fields:    Translation:HumansAnimalsCells
    180. Gasparetto EL, Pawlak MA, Patel SH, Huse J, Woo JH, Krejza J, Rosenfeld MR, O'Rourke DM, Lustig R, Melhem ER, Wolf RL. Posttreatment recurrence of malignant brain neoplasm: accuracy of relative cerebral blood volume fraction in discriminating low from high malignant histologic volume fraction. Radiology. 2009 Mar; 250(3):887-96. PMID: 19244052.
      Citations: 42     Fields:    Translation:Humans
    181. Huse JT, Holland EC. Genetically engineered mouse models of brain cancer and the promise of preclinical testing. Brain Pathol. 2009 Jan; 19(1):132-43. PMID: 19076778; PMCID: PMC2659383.
      Citations: 70     Fields:    Translation:HumansAnimals
    182. Perry A, Miller CR, Gujrati M, Scheithauer BW, Zambrano SC, Jost SC, Raghavan R, Qian J, Cochran EJ, Huse JT, Holland EC, Burger PC, Rosenblum MK. Malignant gliomas with primitive neuroectodermal tumor-like components: a clinicopathologic and genetic study of 53 cases. Brain Pathol. 2009 Jan; 19(1):81-90. PMID: 18452568; PMCID: PMC8094809.
      Citations: 54     Fields:    Translation:Humans
    183. Whitmore RG, Krejza J, Kapoor GS, Huse J, Woo JH, Bloom S, Lopinto J, Wolf RL, Judy K, Rosenfeld MR, Biegel JA, Melhem ER, O'Rourke DM. Prediction of oligodendroglial tumor subtype and grade using perfusion weighted magnetic resonance imaging. J Neurosurg. 2007 Sep; 107(3):600-9. PMID: 17886561.
      Citations: 35     Fields:    Translation:Humans
    184. Huse JT, Pasha TL, Zhang PJ. D2-40 functions as an effective chondroid marker distinguishing true chondroid tumors from chordoma. Acta Neuropathol. 2007 Jan; 113(1):87-94. PMID: 17021752.
      Citations: 8     Fields:    Translation:Humans
    185. Elmariah SB, Huse J, Mason B, Leroux P, Lustig RA. Multicentric glioblastoma multiforme in a patient with BRCA-1 invasive breast cancer. Breast J. 2006 Sep-Oct; 12(5):470-4. PMID: 16958968.
      Citations: 9     Fields:    Translation:Humans
    186. Huse JT, Doms RW. Neurotoxic traffic: uncovering the mechanics of amyloid production in Alzheimer's disease. Traffic. 2001 Feb; 2(2):75-81. PMID: 11247305.
      Citations: 9     Fields:    Translation:Humans
    187. Integrated Genomics for Pinpointing Survival Loci within Arm-Level Somatic Copy Number Alterations. Cancer Cell. 29:737-750.
    188. Establishing a Robust Molecular Taxonomy for Diffuse Gliomas of Adulthood. Surgical Pathology Clinics. 9:379-390.
    189. Radiotherapy and temozolomide for anaplastic astrocytic gliomas. Journal of Neuro-Oncology. 123:129-134.
    190. A multicenter, phase II, randomized, noncomparative clinical trial of radiation and temozolomide with or without vandetanib in newly diagnosed glioblastoma patients. Clinical Cancer Research. 21:3610-3618.
    191. Polymorphous low-grade neuroepithelial tumor of the young (PLNTY). Acta Neuropathologica. 1-13.
    192. Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma. Neuro-Oncology. 18:557-564.
    193. Pretreatment Dynamic Susceptibility Contrast MRI Perfusion in Glioblastoma. Clinical Neuroradiology. 25:143-150.
    194. A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors. Pediatric Blood and Cancer.
    195. IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation. Scientific Reports. 6.
    196. The ABCG2 resistance network of glioblastoma. Cell Cycle. 8:2937-2945.
    197. Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma. Cell. 164:550-563.
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