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ERIK PHILIP SULMAN

TitleAssociate Professor
InstitutionMD Anderson
DepartmentRadiation Oncology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Weller M, Albert NL, Galldiks N, Bink A, Preusser M, Sulman EP, Treyer V, Wen PY, Tonn JC, Le Rhun E, Albert NL, Galldiks N, Bink A, Sulman EP, Wen PY, Tonn JC. Targeted radionuclide therapy for gliomas: Emerging clinical trial landscape. Neuro Oncol. 2024 Dec 09; 26(Supplement_9):S208-S214. PMID: 39107236; PMCID: PMC11631073.
      Citations: 1     Fields:    Translation:Humans
    2. Mair MJ, Tabouret E, Johnson DR, Sulman EP, Wen PY, Preusser M, Albert NL, Mair MJ, Johnson DR, Sulman EP, Wen PY. Radioligand therapies in meningioma: Evidence and future directions. Neuro Oncol. 2024 Dec 09; 26(Supplement_9):S215-S228. PMID: 38702966; PMCID: PMC11631075.
      Citations: 1     Fields:    Translation:Humans
    3. Sarkaria JN, Ballman KV, Kizilbash SH, Sulman EP, Giannini C, Friday BB, Butowski NA, Mohile NA, Piccioni DE, Battiste JD, Drappatz J, Campian JL, Mashru S, Jaeckle KA, O'Brien BJ, Dixon JG, Kabat BF, Laack NL, Hu LS, Kaufmann T, Kumthekar P, Ellingson BM, Anderson SK, Galanis E. Efficacy of Adding Veliparib to Temozolomide for Patients With MGMT-Methylated Glioblastoma: A Randomized Clinical Trial. JAMA Oncol. 2024 Dec 01; 10(12):1637-1644. PMID: 39480453; PMCID: PMC11528341.
      Citations: 1     Fields:    Translation:HumansCellsCTClinical Trials
    4. Strauss JD, Gilbert MR, Mehta M, Li A, Ms RZ, Bondy ML, Sulman EP, Yuan Y, Liu Y, Vera E, Wendland MM, Stieber VW, Puduvalli VK, Choi S, Martinez NL, Robins HI, Hunter GK, Lin CF, Guedes VA, Richard MA, Pugh SL, Armstrong TS, Scheurer ME. Clinical and Genetic Markers of Vascular Toxicity in Glioblastoma Patients: Insights from NRG Oncology RTOG-0825. Neuro Oncol. 2024 Nov 16. PMID: 39549280.
      Citations:    Fields:    
    5. Meng Y, Bernstein K, Mashiach E, Santhumayor B, Kannapadi N, Gurewitz J, Snuderl M, Pacione D, Sen C, Donahue B, Silverman JS, Sulman E, Golfinos J, Kondziolka D. Outcomes of Radiosurgery for WHO Grade 2 Meningiomas: The Role of Ki-67 Index in Guiding the Tumor Margin Dose. Neurosurgery. 2024 Nov 11. PMID: 39526756.
      Citations:    Fields:    
    6. Rahman R, Preusser M, Tsien C, Le Rhun E, Sulman EP, Wen PY, Minniti G, Weller M. Point/Counterpoint: The role of reirradiation in recurrent glioblastoma. Neuro Oncol. 2024 Nov 11. PMID: 39527460.
      Citations:    Fields:    
    7. Wang JZ, Landry AP, Raleigh DR, Sahm F, Walsh KM, Goldbrunner R, Yefet LS, Tonn JC, Gui C, Ostrom QT, Barnholtz-Sloan J, Perry A, Ellenbogen Y, Hanemann CO, Jungwirth G, Jenkinson MD, Tabatabai G, Mathiesen TI, McDermott MW, Tatagiba M, la Foug?re C, Maas SLN, Galldiks N, Albert NL, Brastianos PK, Ehret F, Minniti G, Lamszus K, Ricklefs FL, Schittenhelm J, Drummond KJ, Dunn IF, Pathmanaban ON, Cohen-Gadol A, Sulman EP, Tabouret E, Le Rhun E, Mawrin C, Moliterno J, Weller M, Bi WL, Gao A, Yip S, Niyazi M, International Consortium on Meningiomas (ICOM), Aldape K, Wen PY, Short S, Preusser M, Nassiri F, Zadeh G, Wang JZ, Landry AP, Raleigh DR, Walsh KM, Yefet LS, Gui C, Ostrom QT, Barnholtz-Sloan J, Ellenbogen Y, Jenkinson MD, Tabatabai G, Mathiesen TI, McDermott MW, Tatagiba M, la Foug?re C, Maas SLN, Galldiks N, Brastianos PK, Ehret F, Minniti G, Lamszus K, Ricklefs FL, Schittenhelm J, Dunn IF, Pathmanaban ON, Cohen-Gadol AA, Sulman EP, Tabouret E, Moliterno J, Weller M, Bi WL, Gao A, Yip S, Niyazi M, Aldape K, Preusser M, Nassiri F, Zadeh G. Meningioma: International Consortium on Meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients. Neuro Oncol. 2024 Oct 03; 26(10):1742-1780. PMID: 38695575; PMCID: PMC11449035.
      Citations: 1     Fields:    Translation:Humans
    8. Sener U, Sulman EP, Sarkaria JN, Sener UT, Sulman EP, Sarkaria JN. Temozolomide use in elderly patients with MGMT promoter unmethylated glioblastoma: Is it finally time to dismount a dead horse? Neuro Oncol. 2024 Oct 03; 26(10):1876-1877. PMID: 39081224; PMCID: PMC11449039.
      Citations:    Fields:    Translation:HumansCells
    9. Kim SH, Joshi K, Ezhilarasan R, Myers TR, Siu J, Gu C, Nakano-Okuno M, Taylor D, Minata M, Sulman EP, Lee J, Bhat KPL, Salcini AE, Nakano I. EZH2 Protects Glioma Stem Cells from Radiation-Induced Cell Death in a MELK/FOXM1-Dependent Manner. Stem Cell Reports. 2024 10 08; 19(10):1516. PMID: 39389676; PMCID: PMC11561452.
      Citations:    Fields:    Translation:HumansAnimalsCells
    10. Meng Y, Santhumayor B, Mashiach E, Bernstein K, Gurewitz J, Cooper BT, Sulman E, Silverman J, Kondziolka D. Integral Dose or Mean Dose for Predicting Radiosurgery Response in Patients With Trigeminal Neuralgia: A Proposal to Target the Narrowest Part of the Nerve. Neurosurgery. 2024 Aug 28. PMID: 39194227.
      Citations:    Fields:    
    11. Karp JM, Modrek AS, Ezhilarasan R, Zhang ZY, Ding Y, Graciani M, Sahimi A, Silvestro M, Chen T, Li S, Wong KK, Ramkhelawon B, Bhat KP, Sulman EP, Karp JM, Modrek AS, Ezhilarasan R, Zhang ZY, Ding Y, Graciani M, Sahimi A, Silvestro M, Chen T, Li S, Wong KK, Ramkhelawon B, Bhat KP, Sulman EP. Deconvolution of the tumor-educated platelet transcriptome reveals activated platelet and inflammatory cell transcript signatures. JCI Insight. 2024 Aug 27; 9(19). PMID: 39190500; PMCID: PMC11466191.
      Citations:    Fields:    Translation:HumansCells
    12. Rahman R, Shi DD, Reitman ZJ, Hamerlik P, de Groot JF, Haas-Kogan DA, D'Andrea AD, Sulman EP, Tanner K, Agar NYR, Sarkaria JN, Tinkle CL, Bindra RS, Mehta MP, Wen PY. DNA damage response in brain tumors: A Society for Neuro-Oncology consensus review on mechanisms and translational efforts in neuro-oncology. Neuro Oncol. 2024 Aug 05; 26(8):1367-1387. PMID: 38770568; PMCID: PMC11300028.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    13. Fang CS, Wang W, Schroff C, Movahed-Ezazi M, Vasudevaraja V, Serrano J, Sulman EP, Golfinos JG, Orringer D, Galbraith K, Feng Y, Snuderl M. Racial distribution of molecularly classified brain tumors. Neurooncol Adv. 2024 Jan-Dec; 6(1):vdae135. PMID: 39220243; PMCID: PMC11362849.
      Citations:    
    14. Galbraith K, Garcia M, Wei S, Chen A, Schroff C, Serrano J, Pacione D, Placantonakis DG, William CM, Faustin A, Zagzag D, Barbaro M, Eibl MDPGP, Shirahata M, Reuss D, Tran QT, Alom Z, von Deimling A, Orr BA, Sulman EP, Golfinos JG, Orringer DA, Jain R, Lieberman E, Feng Y, Snuderl M, Galbraith K, Garcia M, Chen A, Schroff C, Serrano J, Pacione D, Placantonakis DG, William CM, Faustin A, Zagzag D, Barbaro M, Eibl MDPGP, Shirahata M, Reuss D, Tran QT, Alom Z, von Deimling A, Orr BA, Sulman EP, Golfinos JG, Orringer DA, Jain R, Lieberman E, Snuderl M. Prognostic value of DNA methylation subclassification, aneuploidy, and CDKN2A/B homozygous deletion in predicting clinical outcome of IDH mutant astrocytomas. Neuro Oncol. 2024 Jun 03; 26(6):1042-1051. PMID: 38243818; PMCID: PMC11145445.
      Citations: 2     Fields:    Translation:HumansCells
    15. Nuechterlein N, Shelbourn A, Szulzewsky F, Arora S, Casad M, Pattwell S, Merino-Galan L, Sulman E, Arowa S, Alvinez N, Jung M, Brown D, Tang K, Jackson S, Stoica S, Chittaboina P, Banasavadi-Siddegowda YK, Wirsching HG, Stella N, Shapiro L, Paddison P, Patel AP, Gilbert MR, Abdullaev Z, Aldape K, Pratt D, Holland EC, Cimino PJ. Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype. Genes Dev. 2024 04 17; 38(5-6):273-288. PMID: 38589034; PMCID: PMC11065166.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    16. Kurz SC, Zan E, Cordova C, Troxel AB, Barbaro M, Silverman JS, Snuderl M, Zagzag D, Kondziolka D, Golfinos JG, Chi AS, Sulman EP. Evaluation of the SSTR2-targeted Radiopharmaceutical 177Lu-DOTATATE and SSTR2-specific 68Ga-DOTATATE PET as Imaging Biomarker in Patients with Intracranial Meningioma. Clin Cancer Res. 2024 02 16; 30(4):680-686. PMID: 38048045.
      Citations:    Fields:    Translation:Humans
    17. Berger A, Mullen R, Bernstein K, Mashiach E, Meng Y, Silverman JS, Sulman EP, Golfinos JG, Kondziolka D. Volumetric growth rate of incidentally found meningiomas on immunotherapy. J Neurooncol. 2024 Jan; 166(2):303-307. PMID: 38194196.
      Citations:    Fields:    Translation:Humans
    18. Wefel JS, Deshmukh S, Brown PD, Grosshans DR, Sulman EP, Cerhan JH, Mehta MP, Khuntia D, Shi W, Mishra MV, Suh JH, Laack NN, Chen Y, Curtis AA, Laba JM, Elsayed A, Thakrar A, Pugh SL, Bruner DW. Impact of Apolipoprotein E Genotype on Neurocognitive Function in Patients With Brain Metastases: An Analysis of NRG Oncology's RTOG 0614. Int J Radiat Oncol Biol Phys. 2024 Jul 01; 119(3):846-857. PMID: 38101486; PMCID: PMC11162903.
      Citations: 2     Fields:    Translation:Humans
    19. Sulman EP, Eisenstat DD. Editorial: 365 days of progress in neuro-oncology and neurosurgical oncology. Front Oncol. 2023; 13:1279957. PMID: 37746263; PMCID: PMC10513491.
      Citations:    
    20. Mashiach E, Alzate JD, De Nigris Vasconcellos F, Bernstein K, Donahue BR, Schnurman Z, Gurewitz J, Rotman LE, Adams S, Meyers M, Oratz R, Novik Y, Kwa MJ, Silverman JS, Sulman EP, Golfinos JG, Kondziolka D. Long-term Survival From Breast Cancer Brain Metastases in the Era of Modern Systemic Therapies. Neurosurgery. 2024 01 01; 94(1):154-164. PMID: 37581437.
      Citations:    Fields:    Translation:Humans
    21. Galbraith K, Vasudevaraja V, Serrano J, Shen G, Tran I, Abdallat N, Wen M, Patel S, Movahed-Ezazi M, Faustin A, Spino-Keeton M, Roberts LG, Maloku E, Drexler SA, Liechty BL, Pisapia D, Krasnozhen-Ratush O, Rosenblum M, Shroff S, Bou? DR, Davidson C, Mao Q, Suchi M, North P, Hopp A, Segura A, Jarzembowski JA, Parsons L, Johnson MD, Mobley B, Samore W, McGuone D, Gopal PP, Canoll PD, Horbinski C, Fullmer JM, Farooqui MS, Gokden M, Wadhwani NR, Richardson TE, Umphlett M, Tsankova NM, DeWitt JC, Sen C, Placantonakis DG, Pacione D, Wisoff JH, Teresa Hidalgo E, Harter D, William CM, Cordova C, Kurz SC, Barbaro M, Orringer DA, Karajannis MA, Sulman EP, Gardner SL, Zagzag D, Tsirigos A, Allen JC, Golfinos JG, Snuderl M. Clinical utility of whole-genome DNA methylation profiling as a primary molecular diagnostic assay for central nervous system tumors-A prospective study and guidelines for clinical testing. Neurooncol Adv. 2023 Jan-Dec; 5(1):vdad076. PMID: 37476329; PMCID: PMC10355794.
      Citations: 2     
    22. Alzate JD, Mashiach E, Berger A, Bernstein K, Mullen R, Nigris Vasconcellos F, Qu T, Silverman JS, Donahue BR, Cooper BT, Sulman EP, Golfinos JG, Kondziolka D. Low-Dose Radiosurgery for Brain Metastases in the Era of Modern Systemic Therapy. Neurosurgery. 2023 Nov 01; 93(5):1112-1120. PMID: 37326435.
      Citations:    Fields:    Translation:Humans
    23. Schnurman Z, Mashiach E, Link KE, Donahue B, Sulman E, Silverman J, Golfinos JG, Oermann EK, Kondziolka D. Causes of Death in Patients With Brain Metastases. Neurosurgery. 2023 Nov 01; 93(5):986-993. PMID: 37255296.
      Citations:    Fields:    Translation:Humans
    24. Stitzlein LM, Gangadharan A, Walsh LM, Nam D, Espejo AB, Singh MM, Patel KH, Lu Y, Su X, Ezhilarasan R, Gumin J, Singh S, Sulman E, Lang FF, Chandra J. Comparison of pharmacological inhibitors of lysine-specific demethylase 1 in glioblastoma stem cells reveals inhibitor-specific efficacy profiles. Front Neurol. 2023; 14:1112207. PMID: 37082446; PMCID: PMC10111022.
      Citations:    
    25. Gan HK, Preusser M, Seidel C, Lombardi G, Bentsion D, Wick A, Lassman AB, Pugh SL, Wang TJC, Aldape K, Vogelbaum MA, Sulman EP, Won M, Zhang P, Moazami G, Macsai MS, Gilbert MR, Bain EE, Blot V, Ansell PJ, Samanta S, Kundu MG, Armstrong TS, Wefel JS, de Vos FY, Hsu S, Cardona AF, Peterson RA, Gedye C, Bourg V, Curran WJ, Mehta MP. Depatuxizumab mafodotin in EGFR-amplified newly diagnosed glioblastoma: A phase III randomized clinical trial. Neuro Oncol. 2023 02 14; 25(2):339-350. PMID: 35849035; PMCID: PMC9925712.
      Citations:    Fields:    
    26. Berger A, Mullen R, Bernstein K, Alzate JD, Silverman JS, Sulman EP, Donahue BR, Chachoua A, Shum E, Velcheti V, Sabari J, Golfinos JG, Kondziolka D. Extended Survival in Patients With Non-Small-Cell Lung Cancer-Associated Brain Metastases in the Modern Era. Neurosurgery. 2023 07 01; 93(1):50-59. PMID: 36722962.
      Citations:    Fields:    Translation:Humans
    27. Sulman EP, Eisenstat DD. Editorial: Insights in neuro-oncology and neurosurgical oncology: 2021. Front Oncol. 2022; 12:1121113. PMID: 36733357; PMCID: PMC9887312.
      Citations:    
    28. Scheurer ME, Zhou R, Gilbert MR, Bondy ML, Sulman EP, Yuan Y, Liu Y, Vera E, Wendland MM, Youssef EF, Stieber VW, Komaki RR, Flickinger JC, Kenyon LC, Robins HI, Hunter GK, Crocker IR, Chao ST, Pugh SL, Armstrong TS. Germline polymorphisms in MGMT associated with temozolomide-related myelotoxicity risk in patients with glioblastoma treated on NRG Oncology/RTOG 0825. Neurooncol Adv. 2022 Jan-Dec; 4(1):vdac152. PMID: 36299794; PMCID: PMC9587696.
      Citations: 1     
    29. Liu EK, Vasudevaraja V, Sviderskiy VO, Feng Y, Tran I, Serrano J, Cordova C, Kurz SC, Golfinos JG, Sulman EP, Orringer DA, Placantonakis D, Possemato R, Snuderl M. Association of hyperglycemia and molecular subclass on survival in IDH-wildtype glioblastoma. Neurooncol Adv. 2022 Jan-Dec; 4(1):vdac163. PMID: 36382106; PMCID: PMC9653172.
      Citations: 1     
    30. Zhang ZY, Ding Y, Ezhilarasan R, Lhakhang T, Wang Q, Yang J, Modrek AS, Zhang H, Tsirigos A, Futreal A, Draetta GF, Verhaak RGW, Sulman EP. Lineage-coupled clonal capture identifies clonal evolution mechanisms and vulnerabilities of BRAFV600E inhibition resistance in melanoma. Cell Discov. 2022 Oct 06; 8(1):102. PMID: 36202798; PMCID: PMC9537441.
      Citations:    
    31. Berger A, Alzate JD, Bernstein K, Mullen R, McMenomey S, Jethanemest D, Friedmann DR, Smouha E, Sulman EP, Silverman JS, Roland JT, Golfinos JG, Kondziolka D. Modern Hearing Preservation Outcomes After Vestibular Schwannoma Stereotactic Radiosurgery. Neurosurgery. 2022 10 01; 91(4):648-657. PMID: 35973088; PMCID: PMC10553130.
      Citations:    
    32. Modrek AS, Eskilsson E, Ezhilarasan R, Wang Q, Goodman LD, Ding Y, Zhang ZY, Bhat KPL, Le TT, Barthel FP, Tang M, Yang J, Long L, Gumin J, Lang FF, Verhaak RGW, Aldape KD, Sulman EP. PDPN marks a subset of aggressive and radiation-resistant glioblastoma cells. Front Oncol. 2022; 12:941657. PMID: 36059614; PMCID: PMC9434399.
      Citations:    
    33. Yang J, Wang Q, Zhang ZY, Long L, Ezhilarasan R, Karp JM, Tsirigos A, Snuderl M, Wiestler B, Wick W, Miao Y, Huse JT, Sulman EP. DNA methylation-based epigenetic signatures predict somatic genomic alterations in gliomas. Nat Commun. 2022 07 29; 13(1):4410. PMID: 35906213; PMCID: PMC9338285.
      Citations:    Fields:    
    34. Berger A, Bernstein K, Alzate JD, Mullen R, Silverman JS, Sulman EP, Donahue BR, Pavlick AC, Gurewitz J, Mureb M, Mehnert J, Madden K, Palermo A, Weber JS, Golfinos JG, Kondziolka D. Significant survival improvements for patients with melanoma brain metastases: can we reach cure in the current era? J Neurooncol. 2022 Jul; 158(3):471-480. PMID: 35665462.
      Citations:    Fields:    Translation:Humans
    35. Schiff D, Messersmith H, Brastianos PK, Brown PD, Burri S, Dunn IF, Gaspar LE, Gondi V, Jordan JT, Maues J, Mohile N, Redjal N, Stevens GHJ, Sulman EP, van den Bent M, Wallace HJ, Zadeh G, Vogelbaum MA. Radiation Therapy for Brain Metastases: ASCO Guideline Endorsement of ASTRO Guideline. J Clin Oncol. 2022 07 10; 40(20):2271-2276. PMID: 35561283.
      Citations:    Fields:    Translation:Humans
    36. Liu EK, Oh C, Kondziolka D, Sulman EP. Risk of Second Primary Neoplasms of the Central Nervous System. Adv Radiat Oncol. 2022 Jul-Aug; 7(4):100969. PMID: 35814854; PMCID: PMC9260125.
      Citations:    
    37. Bagley SJ, Kothari S, Rahman R, Lee EQ, Dunn GP, Galanis E, Chang SM, Nabors LB, Ahluwalia MS, Stupp R, Mehta MP, Reardon DA, Grossman SA, Sulman EP, Sampson JH, Khagi S, Weller M, Cloughesy TF, Wen PY, Khasraw M. Glioblastoma Clinical Trials: Current Landscape and Opportunities for Improvement. Clin Cancer Res. 2022 02 15; 28(4):594-602. PMID: 34561269; PMCID: PMC9044253.
      Citations: 4     Fields:    Translation:Humans
    38. Danussi C, Bose P, Parthasarathy PT, Silberman PC, Van Arnam JS, Vitucci M, Tang OY, Heguy A, Wang Y, Chan TA, Riggins GJ, Sulman EP, Lang FF, Creighton CJ, Deneen B, Miller CR, Picketts DJ, Kannan K, Huse JT. Author Correction: Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling. Nat Commun. 2022 Jan 05; 13(1):190. PMID: 34987156; PMCID: PMC8733027.
      Citations:    Fields:    
    39. Vogelbaum MA, Brown PD, Messersmith H, Brastianos PK, Burri S, Cahill D, Dunn IF, Gaspar LE, Gatson NTN, Gondi V, Jordan JT, Lassman AB, Maues J, Mohile N, Redjal N, Stevens G, Sulman E, van den Bent M, Wallace HJ, Weinberg JS, Zadeh G, Schiff D. Treatment for Brain Metastases: ASCO-SNO-ASTRO Guideline. J Clin Oncol. 2022 02 10; 40(5):492-516. PMID: 34932393.
      Citations: 14     Fields:    Translation:Humans
    40. London D, Patel DN, Donahue B, Navarro RE, Gurewitz J, Silverman JS, Sulman E, Bernstein K, Palermo A, Golfinos JG, Sabari JK, Shum E, Velcheti V, Chachoua A, Kondziolka D. The incidence and predictors of new brain metastases in patients with non-small cell lung cancer following discontinuation of systemic therapy. J Neurosurg. 2022 Aug 01; 137(2):544-554. PMID: 34891140.
      Citations:    Fields:    
    41. Wefel JS, Zhou R, Sulman EP, Boehling NS, Armstrong GN, Tsavachidis S, Liang FW, Etzel CJ, Kahalley LS, Small BJ, Scheurer ME, Bondy ML, Liu Y. Genetic modulation of longitudinal change in neurocognitive function among adult glioma patients. J Neurooncol. 2022 Jan; 156(1):185-193. PMID: 34817796.
      Citations:    Fields:    Translation:HumansCells
    42. Bunevicius A, Pikis S, Kondziolka D, Patel DN, Bernstein K, Sulman EP, Lee CC, Yang HC, Cifarelli CP, Arsanious DE, Dahshan BA, Weir JS, Speckter H, Mota A, Tripathi M, Kumar N, Warnick RE, Peker S, Samanci Y, Barnett G, Hefnawi FE, Al Sideiri G, Sheehan J, Delabar V, Mathieu D. Stereotactic radiosurgery for IDH wild type glioblastoma: an international, multicenter study. J Neurooncol. 2021 Dec; 155(3):343-351. PMID: 34797526.
      Citations:    Fields:    Translation:Humans
    43. Bunevicius A, Pikis S, Kondziolka D, Patel DN, Bernstein K, Sulman EP, Lee CC, Yang HC, Cifarelli CP, Arsanious DE, Dahshan BA, Weir JS, Speckter H, Mota A, Tripathi M, Kumar N, Warnick RE, Sheehan JP, Delabar V, Mathieu D. Stereotactic radiosurgery for glioblastoma considering tumor genetic profiles: an international multicenter study. J Neurosurg. 2022 Jul 01; 137(1):42-50. PMID: 34740186.
      Citations: 2     Fields:    
    44. Rahman R, Sulman E, Haas-Kogan D, Cagney DN. Update on Radiation Therapy for Central Nervous System Tumors. Hematol Oncol Clin North Am. 2022 02; 36(1):77-93. PMID: 34711456.
      Citations: 1     Fields:    Translation:Humans
    45. Khan S, Mahalingam R, Sen S, Martinez-Ledesma E, Khan A, Gandy K, Lang FF, Sulman EP, Alfaro-Munoz KD, Majd NK, Balasubramaniyan V, de Groot JF. Intrinsic Interferon Signaling Regulates the Cell Death and Mesenchymal Phenotype of Glioblastoma Stem Cells. Cancers (Basel). 2021 Oct 21; 13(21). PMID: 34771447; PMCID: PMC8582372.
      Citations: 1     
    46. Sim HW, McDonald KL, Lwin Z, Barnes EH, Rosenthal M, Foote MC, Koh ES, Back M, Wheeler H, Sulman EP, Buckland ME, Fisher L, Leonard R, Hall M, Ashley DM, Yip S, Simes J, Khasraw M. A randomized phase II trial of veliparib, radiotherapy, and temozolomide in patients with unmethylated MGMT glioblastoma: the VERTU study. Neuro Oncol. 2021 10 01; 23(10):1736-1749. PMID: 33984151; PMCID: PMC8485443.
      Citations: 12     Fields:    Translation:HumansCellsCTClinical Trials
    47. Gudikote JP, Cascone T, Poteete A, Sitthideatphaiboon P, Wu Q, Morikawa N, Zhang F, Peng S, Tong P, Li L, Shen L, Nilsson M, Jones P, Sulman EP, Wang J, Bourdon JC, Johnson FM, Heymach JV. Inhibition of nonsense-mediated decay rescues p53?/? isoform expression and activates the p53 pathway in MDM2-overexpressing and select p53-mutant cancers. J Biol Chem. 2021 11; 297(5):101163. PMID: 34481841; PMCID: PMC8569473.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    48. Brown PD, Chung C, Liu DD, McAvoy S, Grosshans D, Al Feghali K, Mahajan A, Li J, McGovern SL, McAleer MF, Ghia AJ, Sulman EP, Penas-Prado M, de Groot JF, Heimberger AB, Wang J, Armstrong TS, Gilbert MR, Guha-Thakurta N, Wefel JS. A prospective phase II randomized trial of proton radiotherapy vs intensity-modulated radiotherapy for patients with newly diagnosed glioblastoma. Neuro Oncol. 2021 08 02; 23(8):1337-1347. PMID: 33647972; PMCID: PMC8328012.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    49. Byun DJ, Modrek AS, Sulman EP. Insight into the public's interest in tumour treating fields. Br J Cancer. 2021 09; 125(6):901-903. PMID: 34316021; PMCID: PMC8437973.
      Citations:    Fields:    Translation:Humans
    50. Al Feghali KA, Randall JW, Liu DD, Wefel JS, Brown PD, Grosshans DR, McAvoy SA, Farhat MA, Li J, McGovern SL, McAleer MF, Ghia AJ, Paulino AC, Sulman EP, Penas-Prado M, Wang J, de Groot J, Heimberger AB, Armstrong TS, Gilbert MR, Mahajan A, Guha-Thakurta N, Chung C. Phase II trial of proton therapy versus photon IMRT for GBM: secondary analysis comparison of progression-free survival between RANO versus clinical assessment. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab073. PMID: 34337411; PMCID: PMC8320688.
      Citations:    
    51. Kocakavuk E, Anderson KJ, Varn FS, Johnson KC, Amin SB, Sulman EP, Lolkema MP, Barthel FP, Verhaak RGW. Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer. Nat Genet. 2021 07; 53(7):1088-1096. PMID: 34045764; PMCID: PMC8483261.
      Citations: 18     Fields:    Translation:Humans
    52. Kavi A, Gurewitz J, Benjamin CG, Silverman JS, Bernstein K, Mureb M, Oh C, Sulman EP, Donahue B, Kondziolka D. Hippocampal sparing in patients receiving radiosurgery for =25 brain metastases. Radiother Oncol. 2021 08; 161:65-71. PMID: 34052342.
      Citations:    Fields:    Translation:Humans
    53. Puca F, Yu F, Bartolacci C, Pettazzoni P, Carugo A, Huang-Hobbs E, Liu J, Zanca C, Carbone F, Del Poggetto E, Gumin J, Dasgupta P, Seth S, Srinivasan S, Lang FF, Sulman EP, Lorenzi PL, Tan L, Shan M, Tolstyka ZP, Kachman M, Zhang L, Gao S, Deem AK, Genovese G, Scaglioni PP, Lyssiotis CA, Viale A, Draetta GF. Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma. Cancer Discov. 2021 11; 11(11):2904-2923. PMID: 34039636; PMCID: PMC8711129.
      Citations: 1     Fields:    Translation:HumansCells
    54. Sulman EP, Eisenstat DD. World Cancer Day 2021 - Perspectives in Pediatric and Adult Neuro-Oncology. Front Oncol. 2021; 11:659800. PMID: 34041027; PMCID: PMC8142853.
      Citations: 2     
    55. Tanese N, Placantonakis DG, Sulman EP, Rivera R, Du KL, Gerber NK, David G, Chesler M, Modrek AS, Philips MR, Cangiarella J. Breaking Tradition to Bridge Bench and Bedside: Accelerating the MD-PhD-Residency Pathway. Acad Med. 2021 04 01; 96(4):518-521. PMID: 33464738.
      Citations:    Fields:    Translation:Humans
    56. Mohan R, Liu AY, Brown PD, Mahajan A, Dinh J, Chung C, McAvoy S, McAleer MF, Lin SH, Li J, Ghia AJ, Zhu C, Sulman EP, de Groot JF, Heimberger AB, McGovern SL, Grassberger C, Shih H, Ellsworth S, Grosshans DR. Proton therapy reduces the likelihood of high-grade radiation-induced lymphopenia in glioblastoma patients: phase II randomized study of protons vs photons. Neuro Oncol. 2021 02 25; 23(2):284-294. PMID: 32750703; PMCID: PMC7906048.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    57. Mrugala MM, Ostrom QT, Pressley SM, Taylor JW, Thomas AA, Wefel JS, Coven SL, Acquaye AA, Haynes C, Agnihotri S, Lim M, Peters KB, Sulman EP, Salcido JT, Butowski NA, Hervey-Jumper S, Mansouri A, Oliver KR, Porter AB, Nassiri F, Schiff D, Dunbar EM, Hegi ME, Armstrong TS, van den Bent MJ, Chang SM, Zadeh G, Chheda MG. The state of neuro-oncology during the COVID-19 pandemic: a worldwide assessment. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab035. PMID: 34007966; PMCID: PMC7928618.
      Citations: 1     
    58. Huang T, Yang Y, Song X, Wan X, Wu B, Sastry N, Horbinski CM, Zeng C, Tiek D, Goenka A, Liu F, Brennan CW, Kessler JA, Stupp R, Nakano I, Sulman EP, Nishikawa R, James CD, Zhang W, Xu W, Hu B, Cheng SY. PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells. Mol Cell. 2021 03 18; 81(6):1276-1291.e9. PMID: 33539787; PMCID: PMC7979509.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    59. Lee WC, Reuben A, Hu X, McGranahan N, Chen R, Jalali A, Negrao MV, Hubert SM, Tang C, Wu CC, Lucas AS, Roh W, Suda K, Kim J, Tan AC, Peng DH, Lu W, Tang X, Chow CW, Fujimoto J, Behrens C, Kalhor N, Fukumura K, Coyle M, Thornton R, Gumbs C, Li J, Wu CJ, Little L, Roarty E, Song X, Lee JJ, Sulman EP, Rao G, Swisher S, Diao L, Wang J, Heymach JV, Huse JT, Scheet P, Wistuba II, Gibbons DL, Futreal PA, Zhang J, Gomez D, Zhang J. Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity. Genome Biol. 2020 11 04; 21(1):271. PMID: 33148332; PMCID: PMC7640699.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    60. Teruel JR, Malin M, Liu EK, McCarthy A, Hu K, Cooper BT, Sulman EP, Silverman JS, Barbee D. Full automation of spinal stereotactic radiosurgery and stereotactic body radiation therapy treatment planning using Varian Eclipse scripting. J Appl Clin Med Phys. 2020 Oct; 21(10):122-131. PMID: 32965754; PMCID: PMC7592968.
      Citations: 2     Fields:    Translation:Humans
    61. Cui X, Ma C, Vasudevaraja V, Serrano J, Tong J, Peng Y, Delorenzo M, Shen G, Frenster J, Morales RT, Qian W, Tsirigos A, Chi AS, Jain R, Kurz SC, Sulman EP, Placantonakis DG, Snuderl M, Chen W. Dissecting the immunosuppressive tumor microenvironments in Glioblastoma-on-a-Chip for optimized PD-1 immunotherapy. Elife. 2020 09 10; 9. PMID: 32909947; PMCID: PMC7556869.
      Citations: 24     Fields:    
    62. Sa JK, Chang N, Lee HW, Cho HJ, Ceccarelli M, Cerulo L, Yin J, Kim SS, Caruso FP, Lee M, Kim D, Oh YT, Lee Y, Her NG, Min B, Kim HJ, Jeong DE, Kim HM, Kim H, Chung S, Woo HG, Lee J, Kong DS, Seol HJ, Lee JI, Kim J, Park WY, Wang Q, Sulman EP, Heimberger AB, Lim M, Park JB, Iavarone A, Verhaak RGW, Nam DH. Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma. Genome Biol. 2020 08 26; 21(1):216. PMID: 32847614; PMCID: PMC7448990.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    63. Vougiouklakis T, Aung PP, Vasudevaraja V, Prieto VG, Torres-Cabala CA, Sulman EP, Snuderl M, Jour G. Correlative study of epigenetic regulation of tumor microenvironment in spindle cell melanomas and cutaneous malignant peripheral nerve sheath tumors. Sci Rep. 2020 08 03; 10(1):12996. PMID: 32747660; PMCID: PMC7398924.
      Citations: 1     Fields:    Translation:Humans
    64. Chen Z, Herting CJ, Ross JL, Gabanic B, Puigdelloses Vallcorba M, Szulzewsky F, Wojciechowicz ML, Cimino PJ, Ezhilarasan R, Sulman EP, Ying M, Ma'ayan A, Read RD, Hambardzumyan D. Genetic driver mutations introduced in identical cell-of-origin in murine glioblastoma reveal distinct immune landscapes but similar response to checkpoint blockade. Glia. 2020 10; 68(10):2148-2166. PMID: 32639068; PMCID: PMC7512141.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    65. Liu EK, Yu S, Sulman EP, Kurz SC. Racial and socioeconomic disparities differentially affect overall and cause-specific survival in glioblastoma. J Neurooncol. 2020 Aug; 149(1):55-64. PMID: 32617722.
      Citations: 3     Fields:    Translation:Humans
    66. Ott M, Kassab C, Marisetty A, Hashimoto Y, Wei J, Zamler D, Leu JS, Tomaszowski KH, Sabbagh A, Fang D, Gupta P, Priebe W, Zielinski RJ, Burks JK, Long JP, Kong LY, Fuller GN, DeGroot J, Sulman EP, Heimberger AB. Radiation with STAT3 Blockade Triggers Dendritic Cell-T cell Interactions in the Glioma Microenvironment and Therapeutic Efficacy. Clin Cancer Res. 2020 09 15; 26(18):4983-4994. PMID: 32605912; PMCID: PMC9341321.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    67. Narayan RS, Molenaar P, Teng J, Cornelissen FMG, Roelofs I, Menezes R, Dik R, Lagerweij T, Broersma Y, Petersen N, Marin Soto JA, Brands E, van Kuiken P, Lecca MC, Lenos KJ, In 't Veld SGJG, van Wieringen W, Lang FF, Sulman E, Verhaak R, Stalpers LJA, Vermeulen L, Watts C, Bailey D, Slotman BJ, Versteeg R, Noske D, Sminia P, Tannous BA, Wurdinger T, Koster J, Westerman BA, Baumert BG. A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities. Nat Commun. 2020 06 10; 11(1):2935. PMID: 32523045; PMCID: PMC7287046.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    68. Liu EK, Silverman JS, Sulman EP. Stereotactic Radiation for Treating Primary and Metastatic Neoplasms of the Spinal Cord. Front Oncol. 2020; 10:907. PMID: 32582555; PMCID: PMC7295942.
      Citations: 1     
    69. Liu EK, Sulman EP, Wen PY, Kurz SC. Novel Therapies for Glioblastoma. Curr Neurol Neurosci Rep. 2020 05 22; 20(7):19. PMID: 32445058.
      Citations: 22     Fields:    Translation:Humans
    70. Patel RR, Verma V, Miller AB, Lin TA, Jethanandani A, Espinoza AF, Mainwaring W, Augustyn A, Fuller CD, Sulman EP, Yeboa DN, Chung CC, McAleer MF, Li J, Yoshor D, de Groot JF, Mandel JJ, Ludmir EB. Exclusion of patients with brain metastases from cancer clinical trials. Neuro Oncol. 2020 04 15; 22(4):577-579. PMID: 31900480; PMCID: PMC7158639.
      Citations: 3     Fields:    Translation:Humans
    71. Vaubel RA, Tian S, Remonde D, Schroeder MA, Mladek AC, Kitange GJ, Caron A, Kollmeyer TM, Grove R, Peng S, Carlson BL, Ma DJ, Sarkar G, Evers L, Decker PA, Yan H, Dhruv HD, Berens ME, Wang Q, Marin BM, Klee EW, Califano A, LaChance DH, Eckel-Passow JE, Verhaak RG, Sulman EP, Burns TC, Meyer FB, O'Neill BP, Tran NL, Giannini C, Jenkins RB, Parney IF, Sarkaria JN. Genomic and Phenotypic Characterization of a Broad Panel of Patient-Derived Xenografts Reflects the Diversity of Glioblastoma. Clin Cancer Res. 2020 03 01; 26(5):1094-1104. PMID: 31852831; PMCID: PMC7056576.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    72. Wu S, Gao F, Zheng S, Zhang C, Martinez-Ledesma E, Ezhilarasan R, Ding J, Li X, Feng N, Multani A, Sulman EP, Verhaak RG, de Groot JF, Heffernan TP, Yung WKA, Koul D. EGFR Amplification Induces Increased DNA Damage Response and Renders Selective Sensitivity to Talazoparib (PARP Inhibitor) in Glioblastoma. Clin Cancer Res. 2020 03 15; 26(6):1395-1407. PMID: 31852834.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    73. Pradhan D, Jour G, Vasudevaraja V, Tetzlaff MT, Nagarajan P, Curry JL, Ivan D, Long L, Ding Y, Ezhilarasan R, Sulman EP, Diab A, Hwu WJ, Prieto VG, Torres-Cabala CA, Aung PP, Milton D. Aberrant DNA Methylation Predicts Melanoma-Specific Survival in Patients with Acral Melanoma. Cancers (Basel). 2019 Dec 16; 11(12). PMID: 31888295; PMCID: PMC6966546.
      Citations: 4     
    74. Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Galatro T, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Nagahashi Marie SK, Lindahl E, Gahman TC, Shiau AK, Zhou H, DeGroot J, Sulman EP, Cavenee WK, Kolodner RD, Chen CC, Furnari FB. Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. 2019 Dec 09; 36(6):690-691. PMID: 31821785; PMCID: PMC6946119.
      Citations: 6     Fields:    
    75. Bledea R, Vasudevaraja V, Patel S, Stafford J, Serrano J, Esposito G, Tredwin LM, Goodman N, Kloetgen A, Golfinos JG, Zagzag D, Weigelt B, Iafrate AJ, Sulman EP, Chi AS, Dogan S, Reis-Filho JS, Chiang S, Placantonakis D, Tsirigos A, Snuderl M. Functional and topographic effects on DNA methylation in IDH1/2 mutant cancers. Sci Rep. 2019 11 14; 9(1):16830. PMID: 31727977; PMCID: PMC6856069.
      Citations: 11     Fields:    Translation:HumansCells
    76. Burgenske DM, Yang J, Decker PA, Kollmeyer TM, Kosel ML, Mladek AC, Caron AA, Vaubel RA, Gupta SK, Kitange GJ, Sicotte H, Youland RS, Remonde D, Voss JS, Fritcher EGB, Kolsky KL, Ida CM, Meyer FB, Lachance DH, Parney IJ, Kipp BR, Giannini C, Sulman EP, Jenkins RB, Eckel-Passow JE, Sarkaria JN. Molecular profiling of long-term IDH-wildtype glioblastoma survivors. Neuro Oncol. 2019 11 04; 21(11):1458-1469. PMID: 31346613; PMCID: PMC6827834.
      Citations: 21     Fields:    Translation:HumansCellsCTClinical Trials
    77. Yang Y, Dodbele S, Park T, Glass R, Bhat K, Sulman EP, Zhang Y, Abounader R. MicroRNA-29a inhibits glioblastoma stem cells and tumor growth by regulating the PDGF pathway. J Neurooncol. 2019 Oct; 145(1):23-34. PMID: 31482267; PMCID: PMC10880555.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    78. Ludmir EB, Mahajan A, Ahern V, Ajithkumar T, Alapetite C, Bindra RS, Bishop AJ, Bolle S, Brown PD, Chalmers AJ, Chang EL, Chung C, Esiashvili N, Gandola L, Ghia AJ, Gondi V, Grosshans DR, Harrabi SB, Horan G, Indelicato DJ, Jalali R, Janssens GO, Laack NN, Laperriere N, Laprie A, Li J, Marcus KJ, McGovern SL, Merchant TE, Merrell KW, Parkes J, Paulino AC, Schwarz R, Shih HA, Sulman EP, Taylor RE, Thorp N, Timmermann B, Wheeler G, Wolden SL, Woodhouse KD, Yeboa DN, Yock TI, Kortmann RD, McAleer MF, Bernier-Chastagner V, Carrie C, Dieckmann K, Krause M, Padovani L, Souhami L. Assembling the brain trust: the multidisciplinary imperative in neuro-oncology. Nat Rev Clin Oncol. 2019 08; 16(8):521-522. PMID: 31150024.
      Citations: 1     Fields:    Translation:Humans
    79. Gates EDH, Yang J, Fukumura K, Lin JS, Weinberg JS, Prabhu SS, Long L, Fuentes D, Sulman EP, Huse JT, Schellingerhout D. Spatial Distance Correlates With Genetic Distance in Diffuse Glioma. Front Oncol. 2019; 9:676. PMID: 31417865; PMCID: PMC6682615.
      Citations: 4     
    80. Farooqi A, Yang J, Sharin V, Ezhilarasan R, Danussi C, Alvarez C, Dharmaiah S, Irvin D, Huse J, Sulman EP. Identification of patient-derived glioblastoma stem cell (GSC) lines with the alternative lengthening of telomeres phenotype. Acta Neuropathol Commun. 2019 05 16; 7(1):76. PMID: 31097032; PMCID: PMC6521362.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    81. Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Galatro T, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Nagahashi Marie SK, Lindahl E, Gahman TC, Shiau AK, Zhou H, DeGroot J, Sulman EP, Cavenee WK, Kolodner RD, Chen CC, Furnari FB. Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. 2019 May 13; 35(5):816. PMID: 31085179; PMCID: PMC8717880.
      Citations: 10     Fields:    
    82. Olar A, Tran D, Mehta VP, Reinhardt A, Manekia JH, Garnovskaya M, Ellezam B, Luthra R, Sulman EP, Mohila CA, Campbell GA, Powell SZ, Fuller GN, Aldape KD, Adesina AM. ATRX protein loss and deregulation of PI3K/AKT pathway is frequent in pilocytic astrocytoma with anaplastic features. Clin Neuropathol. 2019 Mar/Apr; 38(2):59-73. PMID: 30499772.
      Citations: 8     Fields:    Translation:HumansCells
    83. Latha K, Yan J, Yang Y, Gressot LV, Kong LY, Manyam G, Ezhilarasan R, Wang Q, Sulman EP, Eric Davis R, Huang S, Fuller GN, Rao A, Heimberger AB, Li S, Rao G. The Role of Fibrinogen-Like Protein 2 on Immunosuppression and Malignant Progression in Glioma. J Natl Cancer Inst. 2019 03 01; 111(3):292-300. PMID: 29947810; PMCID: PMC6410946.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    84. Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Lindahl E, Gahman TC, Shiau AK, Zhou H, DeGroot J, Sulman EP, Cavenee WK, Kolodner RD, Chen CC, Furnari FB, Galatro T, Nagahashi Marie SK. Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. 2019 03 18; 35(3):504-518.e7. PMID: 30827889; PMCID: PMC6424615.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    85. Wang Y, Yang J, Wild AT, Wu WH, Shah R, Danussi C, Riggins GJ, Kannan K, Sulman EP, Chan TA, Huse JT. G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma. Nat Commun. 2019 02 26; 10(1):943. PMID: 30808951; PMCID: PMC6391399.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    86. Minata M, Audia A, Shi J, Lu S, Bernstock J, Pavlyukov MS, Das A, Kim SH, Shin YJ, Lee Y, Koo H, Snigdha K, Waghmare I, Guo X, Mohyeldin A, Gallego-Perez D, Wang J, Chen D, Cheng P, Mukheef F, Contreras M, Reyes JF, Vaillant B, Sulman EP, Cheng SY, Markert JM, Tannous BA, Lu X, Kango-Singh M, Lee LJ, Nam DH, Nakano I, Bhat KP. Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation. Cell Rep. 2019 02 12; 26(7):1893-1905.e7. PMID: 30759398; PMCID: PMC6594377.
      Citations: 69     Fields:    Translation:Humans
    87. Chumakova AP, Hitomi M, Sulman EP, Lathia JD. High-Throughput Automated Single-Cell Imaging Analysis Reveals Dynamics of Glioblastoma Stem Cell Population During State Transition. Cytometry A. 2019 03; 95(3):290-301. PMID: 30729665; PMCID: PMC7927898.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    88. Milgrom SA, Elhalawani H, Lee J, Wang Q, Mohamed ASR, Dabaja BS, Pinnix CC, Gunther JR, Court L, Rao A, Fuller CD, Akhtari M, Aristophanous M, Mawlawi O, Chuang HH, Sulman EP, Lee HJ, Hagemeister FB, Oki Y, Fanale M, Smith GL. A PET Radiomics Model to Predict Refractory Mediastinal Hodgkin Lymphoma. Sci Rep. 2019 02 04; 9(1):1322. PMID: 30718585; PMCID: PMC6361903.
      Citations: 16     Fields:    Translation:HumansCells
    89. Huang T, Wan X, Alvarez AA, James CD, Song X, Yang Y, Sastry N, Nakano I, Sulman EP, Hu B, Cheng SY. MIR93 (microRNA -93) regulates tumorigenicity and therapy response of glioblastoma by targeting autophagy. Autophagy. 2019 06; 15(6):1100-1111. PMID: 30654687; PMCID: PMC6526840.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    90. Yeboa DN, Yu JB, Liao E, Huse J, Penas-Prado M, Kann BH, Sulman E, Grosshans D, Contessa J. Differences in patterns of care and outcomes between grade II and grade III molecularly defined 1p19q co-deleted gliomas. Clin Transl Radiat Oncol. 2019 Feb; 15:46-52. PMID: 30656222; PMCID: PMC6329703.
      Citations: 3     
    91. Spino M, Kurz SC, Chiriboga L, Serrano J, Zeck B, Sen N, Patel S, Shen G, Vasudevaraja V, Tsirigos A, Suryadevara CM, Frenster JD, Tateishi K, Wakimoto H, Jain R, Riina HA, Nicolaides TP, Sulman EP, Cahill DP, Golfinos JG, Isse K, Saunders LR, Zagzag D, Placantonakis DG, Snuderl M, Chi AS. Cell Surface Notch Ligand DLL3 is a Therapeutic Target in Isocitrate Dehydrogenase-mutant Glioma. Clin Cancer Res. 2019 02 15; 25(4):1261-1271. PMID: 30397180; PMCID: PMC7365589.
      Citations: 23     Fields:    Translation:HumansCells
    92. Maraka S, Groves MD, Mammoser AG, Melguizo-Gavilanes I, Conrad CA, Tremont-Lukats IW, Loghin ME, O'Brien BJ, Puduvalli VK, Sulman EP, Hess KR, Aldape KD, Gilbert MR, de Groot JF, Alfred Yung WK, Penas-Prado M. Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma. Cancer. 2019 02 01; 125(3):424-433. PMID: 30359477; PMCID: PMC7180384.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    93. Jour G, Vasudevaraja V, Prieto VG, Snuderl M, Torres-Cabala CA, Al-Rohil R, Sulman EP, Ballester LY, Aung PP. BCAT1 and miR-2504: novel methylome signature distinguishes spindle/desmoplastic melanoma from superficial malignant peripheral nerve sheath tumor. Mod Pathol. 2019 03; 32(3):338-345. PMID: 30310175.
      Citations: 3     Fields:    Translation:HumansCells
    94. Yuan AL, Ricks CB, Bohm AK, Lun X, Maxwell L, Safdar S, Bukhari S, Gerber A, Sayeed W, Bering EA, Pedersen H, Chan JA, Shen Y, Marra M, Kaplan DR, Mason W, Goodman LD, Ezhilarasan R, Kaufmann AB, Cabral M, Robbins SM, Senger DL, Cahill DP, Sulman EP, Cairncross JG, Blough MD. ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts. PLoS One. 2018; 13(8):e0202860. PMID: 30153289; PMCID: PMC6112648.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    95. Zinn PO, Singh SK, Kotrotsou A, Hassan I, Thomas G, Luedi MM, Elakkad A, Elshafeey N, Idris T, Mosley J, Gumin J, Fuller GN, de Groot JF, Baladandayuthapani V, Sulman EP, Kumar AJ, Sawaya R, Lang FF, Piwnica-Worms D, Colen RR. A Coclinical Radiogenomic Validation Study: Conserved Magnetic Resonance Radiomic Appearance of Periostin-Expressing Glioblastoma in Patients and Xenograft Models. Clin Cancer Res. 2018 12 15; 24(24):6288-6299. PMID: 30054278; PMCID: PMC6538261.
      Citations: 37     Fields:    Translation:HumansAnimals
    96. Pietanza MC, Waqar SN, Krug LM, Dowlati A, Hann CL, Chiappori A, Owonikoko TK, Woo KM, Cardnell RJ, Fujimoto J, Long L, Diao L, Wang J, Bensman Y, Hurtado B, de Groot P, Sulman EP, Wistuba II, Chen A, Fleisher M, Heymach JV, Kris MG, Rudin CM, Byers LA. Randomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell Lung Cancer. J Clin Oncol. 2018 08 10; 36(23):2386-2394. PMID: 29906251; PMCID: PMC6085179.
      Citations: 101     Fields:    Translation:HumansCellsCTClinical Trials
    97. Danussi C, Bose P, Parthasarathy PT, Silberman PC, Van Arnam JS, Vitucci M, Tang OY, Heguy A, Wang Y, Chan TA, Riggins GJ, Sulman EP, Lang FF, Creighton CJ, Deneen B, Miller CR, Picketts DJ, Kannan K, Huse JT. Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling. Nat Commun. 2018 03 13; 9(1):1057. PMID: 29535300; PMCID: PMC5849741.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    98. Olar A, Goodman LD, Wani KM, Boehling NS, Sharma DS, Mody RR, Gumin J, Claus EB, Lang FF, Cloughesy TF, Lai A, Aldape KD, DeMonte F, Sulman EP. A gene expression signature predicts recurrence-free survival in meningioma. Oncotarget. 2018 Mar 23; 9(22):16087-16098. PMID: 29662628; PMCID: PMC5882319.
      Citations: 11     Fields:    
    99. Olmez I, Love S, Xiao A, Manigat L, Randolph P, McKenna BD, Neal BP, Boroda S, Li M, Brenneman B, Abounader R, Floyd D, Lee J, Nakano I, Godlewski J, Bronisz A, Sulman EP, Mayo M, Gioeli D, Weber M, Harris TE, Purow B. Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha. Neuro Oncol. 2018 01 22; 20(2):192-202. PMID: 29048560; PMCID: PMC5777487.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    100. Gabrusiewicz K, Li X, Wei J, Hashimoto Y, Marisetty AL, Ott M, Wang F, Hawke D, Yu J, Healy LM, Hossain A, Akers JC, Maiti SN, Yamashita S, Shimizu Y, Dunner K, Zal MA, Burks JK, Gumin J, Nwajei F, Rezavanian A, Zhou S, Rao G, Sawaya R, Fuller GN, Huse JT, Antel JP, Li S, Cooper L, Sulman EP, Chen C, Geula C, Kalluri R, Zal T, Heimberger AB. Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes. Oncoimmunology. 2018; 7(4):e1412909. PMID: 29632728; PMCID: PMC5889290.
      Citations: 122     Fields:    
    101. Luedi MM, Singh SK, Mosley JC, Hassan ISA, Hatami M, Gumin J, Andereggen L, Sulman EP, Lang FF, Stueber F, Fuller GN, Colen RR, Zinn PO. Dexamethasone-mediated oncogenicity in vitro and in an animal model of glioblastoma. J Neurosurg. 2018 12 01; 129(6):1446-1455. PMID: 29328002.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    102. Wu J, Frady LN, Bash RE, Cohen SM, Schorzman AN, Su YT, Irvin DM, Zamboni WC, Wang X, Frye SV, Ewend MG, Sulman EP, Gilbert MR, Earp HS, Miller CR. MerTK as a therapeutic target in glioblastoma. Neuro Oncol. 2018 01 10; 20(1):92-102. PMID: 28605477; PMCID: PMC5761530.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    103. Wang Q, Hu B, Hu X, Kim H, Squatrito M, Scarpace L, deCarvalho AC, Lyu S, Li P, Li Y, Barthel F, Cho HJ, Lin YH, Satani N, Martinez-Ledesma E, Zheng S, Chang E, Olar A, Lan ZD, Finocchiaro G, Phillips JJ, Berger MS, Gabrusiewicz KR, Wang G, Eskilsson E, Hu J, Mikkelsen T, DePinho RA, Muller F, Heimberger AB, Sulman EP, Nam DH, Verhaak RGW, Gabriel Sauv? CE. Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment. Cancer Cell. 2018 01 08; 33(1):152. PMID: 29316430; PMCID: PMC5892424.
      Citations: 78     Fields:    
    104. Dong J, Park SY, Nguyen N, Ezhilarasan R, Martinez-Ledesma E, Wu S, Henry V, Piao Y, Tiao N, Brunell D, Stephan C, Verhaak R, Sulman E, Balasubramaniyan V, de Groot JF. The polo-like kinase 1 inhibitor volasertib synergistically increases radiation efficacy in glioma stem cells. Oncotarget. 2018 Feb 13; 9(12):10497-10509. PMID: 29535822; PMCID: PMC5828226.
      Citations: 8     Fields:    
    105. Mostovenko E, Rezeli M, Lichti CF, Wang Q, Lang FF, Sulman EP, Sahlin KB, Nilsson CL, V?gv?ri ?, Feny? D, Marko-Varga G. Large Scale Identification of Variant Proteins in Glioma Stem Cells. ACS Chem Neurosci. 2018 01 17; 9(1):73-79. PMID: 29254333; PMCID: PMC6008157.
      Citations: 7     Fields:    Translation:HumansCells
    106. Huang T, Kim CK, Alvarez AA, Pangeni RP, Wan X, Song X, Shi T, Yang Y, Sastry N, Horbinski CM, Lu S, Stupp R, Kessler JA, Nishikawa R, Nakano I, Sulman EP, Lu X, James CD, Yin XM, Hu B, Cheng SY. MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma. Cancer Cell. 2017 Dec 11; 32(6):840-855.e8. PMID: 29232556; PMCID: PMC5734934.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    107. Fang P, Boehling NS, Koay EJ, Bucheit AD, Jakob JA, Settle SH, Brown PD, Davies MA, Sulman EP. Melanoma brain metastases harboring BRAF V600K or NRAS mutations are associated with an increased local failure rate following conventional therapy. J Neurooncol. 2018 Mar; 137(1):67-75. PMID: 29198052.
      Citations: 8     Fields:    Translation:Humans
    108. Moreno M, Pedrosa L, Pineda E, Bejarano L, Balasubramaniyan V, Ezhilarasan R, Kallarackal N, Kim SH, Wang J, Audia A, Conroy S, Marin M, Ribalta T, Pujol T, Herreros A, Alonso MM, Graus F, Sulman EP, Piao X, Nakano I, Prat A, Bhat KP, Par? L, Mart?nez J, Tortosa A, Mira H, G?mez-Manzano C, de la Iglesia N. GPR56/ADGRG1 Inhibits Mesenchymal Differentiation and Radioresistance in Glioblastoma. Cell Rep. 2017 Nov 21; 21(8):2183-2197. PMID: 29166609.
      Citations: 29     Fields:    Translation:HumansCells
    109. McNeill RS, Canoutas DA, Stuhlmiller TJ, Dhruv HD, Irvin DM, Bash RE, Angus SP, Herring LE, Simon JM, Skinner KR, Limas JC, Chen X, Schmid RS, Siegel MB, Van Swearingen AED, Hadler MJ, Sulman EP, Sarkaria JN, Anders CK, Graves LM, Berens ME, Johnson GL, Miller CR. Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma. Neuro Oncol. 2017 Oct 19; 19(11):1469-1480. PMID: 28379424; PMCID: PMC5737415.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    110. Boonyawan K, Hess KR, Yang J, Long L, Wang Q, Ezhilarasan R, Auia A, Alfaro-Munoz KD, de Groot JF, Bhat KP, Sulman EP. A relative increase in circulating platelets following chemoradiation predicts for poor survival of patients with glioblastoma. Oncotarget. 2017 Oct 27; 8(52):90488-90495. PMID: 29163847; PMCID: PMC5685768.
      Citations: 7     Fields:    
    111. Ong DST, Hu B, Ho YW, Bristow CA, Wang Q, Multani AS, Chen P, Nezi L, Jiang S, Gorman CE, Monasterio MM, Koul D, Marchesini M, Colla S, Jin EJ, Sulman EP, Spring DJ, Yung WA, Verhaak RGW, Chin L, Wang YA, DePinho RA, Sauv? CG. PAF promotes stemness and radioresistance of glioma stem cells. Proc Natl Acad Sci U S A. 2017 10 24; 114(43):E9086-E9095. PMID: 29073105; PMCID: PMC5664518.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    112. An Y, Jiang W, Kim BYS, Qian JM, Tang C, Fang P, Logan J, D'Souza NM, Haydu LE, Wang XA, Hess KR, Kluger H, Glitza IC, Mahajan A, Welsh JW, Lin SH, Yu JB, Davies MA, Hwu P, Sulman EP, Brown PD, Chiang VLS, Li J. Stereotactic radiosurgery of early melanoma brain metastases after initiation of anti-CTLA-4 treatment is associated with improved intracranial control. Radiother Oncol. 2017 10; 125(1):80-88. PMID: 28916225.
      Citations: 21     Fields:    Translation:Humans
    113. Guerrero PA, Tchaicha JH, Chen Z, Morales JE, McCarty N, Wang Q, Sulman EP, Fuller G, Lang FF, Rao G, McCarty JH. Glioblastoma stem cells exploit the av?8 integrin-TGF?1 signaling axis to drive tumor initiation and progression. Oncogene. 2017 11 23; 36(47):6568-6580. PMID: 28783169; PMCID: PMC5882487.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    114. Li M, Xiao A, Floyd D, Olmez I, Lee J, Godlewski J, Bronisz A, Bhat KPL, Sulman EP, Nakano I, Purow B. CDK4/6 inhibition is more active against the glioblastoma proneural subtype. Oncotarget. 2017 Aug 15; 8(33):55319-55331. PMID: 28903422; PMCID: PMC5589661.
      Citations: 18     Fields:    
    115. Wang Q, Hu B, Hu X, Kim H, Scarpace L, deCarvalho AC, Lyu S, Li P, Li Y, Barthel F, Cho HJ, Lin YH, Satani N, Martinez-Ledesma E, Zheng S, Chang E, Olar A, Lan ZD, Finocchiaro G, Phillips JJ, Berger MS, Gabrusiewicz KR, Wang G, Eskilsson E, Hu J, Mikkelsen T, DePinho RA, Muller F, Heimberger AB, Sulman EP, Nam DH, Verhaak RGW, Squatrito M, Sauv? CG. Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment. Cancer Cell. 2017 07 10; 32(1):42-56.e6. PMID: 28697342; PMCID: PMC5599156.
      Citations: 549     Fields:    Translation:HumansCells
    116. Canella A, Welker AM, Yoo JY, Xu J, Abas FS, Kesanakurti D, Nagarajan P, Beattie CE, Sulman EP, Liu J, Gumin J, Lang FF, Gurcan MN, Kaur B, Sampath D, Puduvalli VK. Efficacy of Onalespib, a Long-Acting Second-Generation HSP90 Inhibitor, as a Single Agent and in Combination with Temozolomide against Malignant Gliomas. Clin Cancer Res. 2017 Oct 15; 23(20):6215-6226. PMID: 28679777; PMCID: PMC5986078.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    117. Mahajan A, Ahmed S, McAleer MF, Weinberg JS, Li J, Brown P, Settle S, Prabhu SS, Lang FF, Levine N, McGovern S, Sulman E, McCutcheon IE, Azeem S, Cahill D, Tatsui C, Heimberger AB, Ferguson S, Ghia A, Demonte F, Raza S, Guha-Thakurta N, Yang J, Sawaya R, Hess KR, Rao G. Post-operative stereotactic radiosurgery versus observation for completely resected brain metastases: a single-centre, randomised, controlled, phase 3 trial. Lancet Oncol. 2017 08; 18(8):1040-1048. PMID: 28687375; PMCID: PMC5560102.
      Citations: 148     Fields:    Translation:HumansCTClinical Trials
    118. Reardon DA, Lassman AB, van den Bent M, Kumthekar P, Merrell R, Scott AM, Fichtel L, Sulman EP, Gomez E, Fischer J, Lee HJ, Munasinghe W, Xiong H, Mandich H, Roberts-Rapp L, Ansell P, Holen KD, Gan HK. Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma. Neuro Oncol. 2017 Jul 01; 19(7):965-975. PMID: 28039367; PMCID: PMC5570193.
      Citations: 54     Fields:    Translation:HumansCTClinical Trials
    119. Shahar T, Rozovski U, Hess KR, Hossain A, Gumin J, Gao F, Fuller GN, Goodman L, Sulman EP, Lang FF. Percentage of mesenchymal stem cells in high-grade glioma tumor samples correlates with patient survival. Neuro Oncol. 2017 05 01; 19(5):660-668. PMID: 28453745; PMCID: PMC5464439.
      Citations: 26     Fields:    Translation:HumansCells
    120. Gittleman H, Lim D, Kattan MW, Chakravarti A, Gilbert MR, Lassman AB, Lo SS, Machtay M, Sloan AE, Sulman EP, Tian D, Vogelbaum MA, Wang TJC, Penas-Prado M, Youssef E, Blumenthal DT, Zhang P, Mehta MP, Barnholtz-Sloan JS. An independently validated nomogram for individualized estimation of survival among patients with newly diagnosed glioblastoma: NRG Oncology RTOG 0525 and 0825. Neuro Oncol. 2017 05 01; 19(5):669-677. PMID: 28453749; PMCID: PMC5464437.
      Citations: 69     Fields:    Translation:Humans
    121. Wang Y, Wu S, Zheng S, Wang S, Wali A, Ezhilarasan R, Sulman EP, Koul D, Alfred Yung WK. APOBEC3G acts as a therapeutic target in mesenchymal gliomas by sensitizing cells to radiation-induced cell death. Oncotarget. 2017 Aug 15; 8(33):54285-54296. PMID: 28903341; PMCID: PMC5589580.
      Citations: 7     Fields:    
    122. Thomas JG, Parker Kerrigan BC, Hossain A, Gumin J, Shinojima N, Nwajei F, Ezhilarasan R, Love P, Sulman EP, Lang FF. Ionizing radiation augments glioma tropism of mesenchymal stem cells. J Neurosurg. 2018 01; 128(1):287-295. PMID: 28362237; PMCID: PMC6008155.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    123. Koul D, Wang S, Wu S, Saito N, Zheng S, Gao F, Kaul I, Setoguchi M, Nakayama K, Koyama K, Shiose Y, Sulman EP, Hirota Y, Yung WKA. Preclinical therapeutic efficacy of a novel blood-brain barrier-penetrant dual PI3K/mTOR inhibitor with preferential response in PI3K/PTEN mutant glioma. Oncotarget. 2017 Mar 28; 8(13):21741-21753. PMID: 28423515; PMCID: PMC5400620.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    124. Zhang S, Zhao BS, Zhou A, Lin K, Zheng S, Lu Z, Chen Y, Sulman EP, Xie K, Majumder S, He C, Huang S, B?gler O. m6A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program. Cancer Cell. 2017 04 10; 31(4):591-606.e6. PMID: 28344040; PMCID: PMC5427719.
      Citations: 573     Fields:    Translation:AnimalsCells
    125. Powell RT, Olar A, Narang S, Rao G, Sulman E, Fuller GN, Rao A. Identification of Histological Correlates of Overall Survival in Lower Grade Gliomas Using a Bag-of-words Paradigm: A Preliminary Analysis Based on Hematoxylin & Eosin Stained Slides from the Lower Grade Glioma Cohort of The Cancer Genome Atlas. J Pathol Inform. 2017; 8:9. PMID: 28382223; PMCID: PMC5364741.
      Citations: 9     
    126. Ballester LY, Fuller GN, Powell SZ, Sulman EP, Patel KP, Luthra R, Routbort MJ. Retrospective Analysis of Molecular and Immunohistochemical Characterization of 381 Primary Brain Tumors. J Neuropathol Exp Neurol. 2017 03 01; 76(3):179-188. PMID: 28395087.
      Citations: 15     Fields:    Translation:Humans
    127. Olar A, Wilson CD, Zadeh G, DeMonte F, Jones DT, Pfister SM, Aldape KD, Wani KM, Sulman EP. Global epigenetic profiling identifies methylation subgroups associated with recurrence-free survival in meningioma. Acta Neuropathol. 2017 03; 133(3):431-444. PMID: 28130639; PMCID: PMC5600514.
      Citations: 49     Fields:    Translation:HumansCells
    128. Singh SK, Mosley JC, Hatami M, Gumin J, Sulman EP, Lang FF, Stueber F, Zinn PO, Colen RR, Luedi MM. A Dexamethasone-regulated Gene Signature Is Prognostic for Poor Survival in Glioblastoma Patients. J Neurosurg Anesthesiol. 2017 Jan; 29(1):46-58. PMID: 27653222; PMCID: PMC5143186.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    129. Sulman EP, Ismaila N, Chang SM. Radiation Therapy for Glioblastoma: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the American Society for Radiation Oncology Guideline. J Oncol Pract. 2017 02; 13(2):123-127. PMID: 27907278.
      Citations: 9     Fields:    Translation:Humans
    130. Sulman EP, Ismaila N, Armstrong TS, Tsien C, Batchelor TT, Cloughesy T, Galanis E, Gilbert M, Gondi V, Lovely M, Mehta M, Mumber MP, Sloan A, Chang SM. Radiation Therapy for Glioblastoma: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the American Society for Radiation Oncology Guideline. J Clin Oncol. 2017 Jan 20; 35(3):361-369. PMID: 27893327.
      Citations: 47     Fields:    Translation:Humans
    131. Hu B, Wang Q, Wang YA, Hua S, Ong D, Lan ZD, Chang Q, Ho YW, Monasterio MM, Lu X, Zhong Y, Zhang J, Deng P, Tan Z, Wang G, Liao WT, Corley LJ, Yan H, Zhang J, You Y, Liu N, Cai L, Finocchiaro G, Phillips JJ, Berger MS, Spring DJ, Hu J, Sulman EP, Fuller GN, Chin L, Verhaak RGW, DePinho RA, Sauv? CG. Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth. Cell. 2016 11 17; 167(5):1281-1295.e18. PMID: 27863244; PMCID: PMC5320931.
      Citations: 110     Fields:    Translation:HumansCells
    132. Huang T, Alvarez AA, Pangeni RP, Horbinski CM, Lu S, Kim SH, James CD, J Raizer J, A Kessler J, Brenann CW, Sulman EP, Finocchiaro G, Tan M, Nishikawa R, Lu X, Nakano I, Hu B, Cheng SY. A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Nat Commun. 2016 10 04; 7:12885. PMID: 27698350; PMCID: PMC5059456.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    133. Hossain MB, Shifat R, Johnson DG, Bedford MT, Gabrusiewicz KR, Cortes-Santiago N, Luo X, Lu Z, Ezhilarasan R, Sulman EP, Jiang H, Li SS, Lang FF, Tyler J, Hung MC, Fueyo J, Gomez-Manzano C. TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1. Sci Adv. 2016 04; 2(4):e1501290. PMID: 27757426; PMCID: PMC5065225.
      Citations: 15     Fields:    Translation:HumansCells
    134. Gabrusiewicz K, Rodriguez B, Wei J, Hashimoto Y, Healy LM, Maiti SN, Thomas G, Zhou S, Wang Q, Elakkad A, Liebelt BD, Yaghi NK, Ezhilarasan R, Huang N, Weinberg JS, Prabhu SS, Rao G, Sawaya R, Langford LA, Bruner JM, Fuller GN, Bar-Or A, Li W, Colen RR, Curran MA, Bhat KP, Antel JP, Cooper LJ, Sulman EP, Heimberger AB. Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype. JCI Insight. 2016; 1(2). PMID: 26973881; PMCID: PMC4784261.
      Citations: 194     Fields:    
    135. Shingu T, Holmes L, Henry V, Wang Q, Latha K, Gururaj AE, Gibson LA, Doucette T, Lang FF, Rao G, Yuan L, Sulman EP, Farrell NP, Priebe W, Hess KR, Wang YA, Hu J, B?gler O. Suppression of RAF/MEK or PI3K synergizes cytotoxicity of receptor tyrosine kinase inhibitors in glioma tumor-initiating cells. J Transl Med. 2016 Feb 09; 14:46. PMID: 26861698; PMCID: PMC4746796.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    136. Kim SH, Ezhilarasan R, Phillips E, Gallego-Perez D, Sparks A, Taylor D, Ladner K, Furuta T, Sabit H, Chhipa R, Cho JH, Mohyeldin A, Beck S, Kurozumi K, Kuroiwa T, Iwata R, Asai A, Kim J, Sulman EP, Cheng SY, Lee LJ, Nakada M, Guttridge D, DasGupta B, Goidts V, Bhat KP, Nakano I. Serine/Threonine Kinase MLK4 Determines Mesenchymal Identity in Glioma Stem Cells in an NF-?B-dependent Manner. Cancer Cell. 2016 Feb 08; 29(2):201-13. PMID: 26859459; PMCID: PMC4837946.
      Citations: 75     Fields:    Translation:HumansAnimalsCells
    137. Sahm F, Schrimpf D, Olar A, Koelsche C, Reuss D, Bissel J, Kratz A, Capper D, Schefzyk S, Hielscher T, Wang Q, Sulman EP, Adeberg S, Koch A, Okuducu AF, Brehmer S, Schittenhelm J, Becker A, Brokinkel B, Schmidt M, Ull T, Gousias K, Kessler AF, Lamszus K, Debus J, Mawrin C, Kim YJ, Simon M, Ketter R, Paulus W, Aldape KD, Herold-Mende C, von Deimling A. TERT Promoter Mutations and Risk of Recurrence in Meningioma. J Natl Cancer Inst. 2016 May; 108(5). PMID: 26668184; PMCID: PMC4849806.
      Citations: 106     Fields:    Translation:HumansCells
    138. Gupta SK, Kizilbash SH, Carlson BL, Mladek AC, Boakye-Agyeman F, Bakken KK, Pokorny JL, Schroeder MA, Decker PA, Cen L, Eckel-Passow JE, Sarkar G, Ballman KV, Reid JM, Jenkins RB, Verhaak RG, Sulman EP, Kitange GJ, Sarkaria JN. Delineation of MGMT Hypermethylation as a Biomarker for Veliparib-Mediated Temozolomide-Sensitizing Therapy of Glioblastoma. J Natl Cancer Inst. 2016 May; 108(5). PMID: 26615020; PMCID: PMC4862419.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    139. Sathyan P, Zinn PO, Marisetty AL, Liu B, Kamal MM, Singh SK, Bady P, Lu L, Wani KM, Veo BL, Gumin J, Kassem DH, Robinson F, Weng C, Baladandayuthapani V, Suki D, Colman H, Bhat KP, Sulman EP, Aldape K, Colen RR, Verhaak RG, Lu Z, Fuller GN, Huang S, Lang FF, Sawaya R, Hegi M, Majumder S. Mir-21-Sox2 Axis Delineates Glioblastoma Subtypes with Prognostic Impact. J Neurosci. 2015 Nov 11; 35(45):15097-112. PMID: 26558781; PMCID: PMC4642241.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    140. Reddy JP, Dawood S, Mitchell M, Debeb BG, Bloom E, Gonzalez-Angulo AM, Sulman EP, Buchholz TA, Woodward WA. Antiepileptic drug use improves overall survival in breast cancer patients with brain metastases in the setting of whole brain radiotherapy. Radiother Oncol. 2015 Nov; 117(2):308-14. PMID: 26482599.
      Citations: 7     Fields:    Translation:Humans
    141. Balasubramaniyan V, Vaillant B, Wang S, Gumin J, Butalid ME, Sai K, Mukheef F, Kim SH, Boddeke HW, Lang F, Aldape K, Sulman EP, Bhat KP, Colman H. Aberrant mesenchymal differentiation of glioma stem-like cells: implications for therapeutic targeting. Oncotarget. 2015 Oct 13; 6(31):31007-17. PMID: 26307681; PMCID: PMC4741584.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    142. Cancer Genome Atlas Research Network, Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, Akbani R, Huse JT, Ciriello G, Poisson LM, Barnholtz-Sloan JS, Berger MS, Brennan C, Colen RR, Colman H, Flanders AE, Giannini C, Grifford M, Iavarone A, Jain R, Joseph I, Kim J, Kasaian K, Mikkelsen T, Murray BA, O'Neill BP, Pachter L, Parsons DW, Sougnez C, Sulman EP, Vandenberg SR, Van Meir EG, von Deimling A, Zhang H, Crain D, Lau K, Mallery D, Morris S, Paulauskis J, Penny R, Shelton T, Sherman M, Yena P, Black A, Bowen J, Dicostanzo K, Gastier-Foster J, Leraas KM, Lichtenberg TM, Pierson CR, Ramirez NC, Taylor C, Weaver S, Wise L, Zmuda E, Davidsen T, Demchok JA, Eley G, Ferguson ML, Hutter CM, Mills Shaw KR, Ozenberger BA, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Ayala B, Baboud J, Chudamani S, Jensen MA, Liu J, Pihl T, Raman R, Wan Y, Wu Y, Ally A, Auman JT, Balasundaram M, Balu S, Baylin SB, Beroukhim R, Bootwalla MS, Bowlby R, Bristow CA, Brooks D, Butterfield Y, Carlsen R, Carter S, Chin L, Chu A, Chuah E, Cibulskis K, Clarke A, Coetzee SG, Dhalla N, Fennell T, Fisher S, Gabriel S, Getz G, Gibbs R, Guin R, Hadjipanayis A, Hayes DN, Hinoue T, Hoadley K, Holt RA, Hoyle AP, Jefferys SR, Jones S, Jones CD, Kucherlapati R, Lai PH, Lander E, Lee S, Lichtenstein L, Ma Y, Maglinte DT, Mahadeshwar HS, Marra MA, Mayo M, Meng S, Meyerson ML, Mieczkowski PA, Moore RA, Mose LE, Mungall AJ, Pantazi A, Parfenov M, Park PJ, Parker JS, Perou CM, Protopopov A, Ren X, Roach J, Schein J, Schumacher SE, Seidman JG, Seth S, Shen H, Simons JV, Sipahimalani P, Soloway MG, Song X, Sun H, Tabak B, Tam A, Tan D, Tang J, Thiessen N, Triche T, Van Den Berg DJ, Veluvolu U, Waring S, Weisenberger DJ, Wilkerson MD, Wong T, Wu J, Xi L, Xu AW, Yang L, Zack TI, Zhang J, Aksoy BA, Arachchi H, Benz C, Bernard B, Carlin D, Cho J, DiCara D, Frazer S, Fuller GN, Gao J, Gehlenborg N, Haussler D, Heiman DI, Iype L, Jacobsen A, Ju Z, Katzman S, Kim H, Knijnenburg T, Kreisberg RB, Lawrence MS, Lee W, Leinonen K, Lin P, Ling S, Liu W, Liu Y, Liu Y, Lu Y, Mills G, Ng S, Noble MS, Paull E, Rao A, Reynolds S, Saksena G, Sanborn Z, Sander C, Schultz N, Senbabaoglu Y, Shen R, Shmulevich I, Sinha R, Stuart J, Sumer SO, Sun Y, Tasman N, Taylor BS, Voet D, Weinhold N, Weinstein JN, Yang D, Yoshihara K, Zheng S, Zhang W, Zou L, Abel T, Sadeghi S, Cohen ML, Eschbacher J, Hattab EM, Raghunathan A, Schniederjan MJ, Aziz D, Barnett G, Barrett W, Bigner DD, Boice L, Brewer C, Calatozzolo C, Campos B, Carlotti CG, Chan TA, Cuppini L, Curley E, Cuzzubbo S, Devine K, DiMeco F, Duell R, Elder JB, Fehrenbach A, Finocchiaro G, Friedman W, Fulop J, Gardner J, Hermes B, Herold-Mende C, Jungk C, Kendler A, Lehman NL, Lipp E, Liu O, Mandt R, McGraw M, Mclendon R, McPherson C, Neder L, Nguyen P, Noss A, Nunziata R, Ostrom QT, Palmer C, Perin A, Pollo B, Potapov A, Potapova O, Rathmell WK, Rotin D, Scarpace L, Schilero C, Senecal K, Shimmel K, Shurkhay V, Sifri S, Singh R, Sloan AE, Smolenski K, Staugaitis SM, Steele R, Thorne L, Tirapelli DP, Unterberg A, Vallurupalli M, Wang Y, Warnick R, Williams F, et al. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med. 2015 Jun 25; 372(26):2481-98. PMID: 26061751; PMCID: PMC4530011.
      Citations: 1192     Fields:    Translation:HumansCells
    143. Hossain A, Gumin J, Gao F, Figueroa J, Shinojima N, Takezaki T, Priebe W, Villarreal D, Kang SG, Joyce C, Sulman E, Wang Q, Marini FC, Andreeff M, Colman H, Lang FF. Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 Pathway. Stem Cells. 2015 Aug; 33(8):2400-15. PMID: 25966666; PMCID: PMC4509942.
      Citations: 102     Fields:    Translation:HumansCells
    144. Subbiah IM, Lei X, Weinberg JS, Sulman EP, Chavez-MacGregor M, Tripathy D, Gupta R, Varma A, Chouhan J, Guevarra RP, Valero V, Gilbert MR, Gonzalez-Angulo AM. Validation and Development of a Modified Breast Graded Prognostic Assessment As a Tool for Survival in Patients With Breast Cancer and Brain Metastases. J Clin Oncol. 2015 Jul 10; 33(20):2239-45. PMID: 25987700; PMCID: PMC5098846.
      Citations: 43     Fields:    Translation:Humans
    145. Liu Y, Zhou R, Sulman EP, Scheurer ME, Boehling N, Armstrong GN, Tsavachidis S, Liang FW, Etzel CJ, Conrad CA, Gilbert MR, Armstrong TS, Bondy ML, Wefel JS. Genetic Modulation of Neurocognitive Function in Glioma Patients. Clin Cancer Res. 2015 Jul 15; 21(14):3340-6. PMID: 25904748; PMCID: PMC4506227.
      Citations: 19     Fields:    Translation:Humans
    146. Olar A, Sulman EP. Molecular Markers in Low-Grade Glioma-Toward Tumor Reclassification. Semin Radiat Oncol. 2015 Jul; 25(3):155-63. PMID: 26050585; PMCID: PMC4500036.
      Citations: 27     Fields:    Translation:Humans
    147. Olar A, Wani KM, Alfaro-Munoz KD, Heathcock LE, van Thuijl HF, Gilbert MR, Armstrong TS, Sulman EP, Cahill DP, Vera-Bolanos E, Yuan Y, Reijneveld JC, Ylstra B, Wesseling P, Aldape KD. IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II-III diffuse gliomas. Acta Neuropathol. 2015 Apr; 129(4):585-96. PMID: 25701198; PMCID: PMC4369189.
      Citations: 123     Fields:    Translation:HumansCells
    148. Kim SH, Joshi K, Ezhilarasan R, Siu J, Gu C, Nakano-Okuno M, Taylor D, Minata M, Sulman EP, Lee J, Bhat KP, Nakano I, Myers TR, Salcini AE. EZH2 protects glioma stem cells from radiation-induced cell death in a MELK/FOXM1-dependent manner. Stem Cell Reports. 2015 Feb 10; 4(2):226-38. PMID: 25601206; PMCID: PMC4325196.
      Citations: 79     Fields:    Translation:HumansAnimalsCells
    149. Mostovenko E, Lichti CF, Ruggles K, Rosenbloom KR, Hancock WS, Paik YK, Omenn GS, LaBaer J, Kroes RA, Hober S, Sulman EP, Lang FF, Fuentes M, Carlsohn E, Emmett MR, Moskal JR, Berven FS, Fehniger TE, Nilsson CL, Feny? D, Uhl?n M, V?gv?ri ?, Andr?n PE, Marko-Varga G. Use of ENCODE resources to characterize novel proteoforms and missing proteins in the human proteome. J Proteome Res. 2015 Feb 06; 14(2):603-8. PMID: 25369122.
      Citations: 7     Fields:    Translation:Humans
    150. Mostovenko E, Wadsworth PA, Lynch GC, Pettitt BM, Sulman EP, Wang Q, Lang FF, Rezeli M, Nilsson CL, Lichti CF, Marko-Varga G, V?gv?ri ?. Systematic identification of single amino acid variants in glioma stem-cell-derived chromosome 19 proteins. J Proteome Res. 2015 Feb 06; 14(2):778-86. PMID: 25399873; PMCID: PMC4324435.
      Citations: 10     Fields:    Translation:HumansCells
    151. Koul D, Yao J, Wan S, Yuan Y, Sulman E, Lang F, Yung WK, Colman H. Retraction: Novel HSP90 inhibitor NVP-HSP990 targets cell-cycle regulators to ablate Olig 2-positive glioma tumor-initiating cells. Cancer Res. 2014 Nov 15; 74(22):6731-2. PMID: 25398854; PMCID: PMC4381954.
      Citations:    Fields:    
    152. Olar A, Wani KM, Sulman EP, Mansouri A, Zadeh G, Wilson CD, DeMonte F, Fuller GN, Aldape KD. Mitotic Index is an Independent Predictor of Recurrence-Free Survival in Meningioma. Brain Pathol. 2015 May; 25(3):266-75. PMID: 25040885; PMCID: PMC4297750.
      Citations: 36     Fields:    Translation:HumansCells
    153. Gilbert MR, Sulman EP, Mehta MP. Bevacizumab for newly diagnosed glioblastoma. N Engl J Med. 2014 05 22; 370(21):2048-9. PMID: 24849088.
      Citations: 42     Fields:    Translation:Humans
    154. Li X, Liu Y, Granberg KJ, Wang Q, Moore LM, Ji P, Gumin J, Sulman EP, Calin GA, Haapasalo H, Nykter M, Shmulevich I, Fuller GN, Lang FF, Zhang W. Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma. Oncogene. 2015 Mar 26; 34(13):1619-1628. PMID: 24747968; PMCID: PMC4205227.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    155. Gilbert MR, Dignam JJ, Armstrong TS, Wefel JS, Blumenthal DT, Vogelbaum MA, Colman H, Chakravarti A, Pugh S, Won M, Jeraj R, Brown PD, Jaeckle KA, Schiff D, Stieber VW, Brachman DG, Werner-Wasik M, Tremont-Lukats IW, Sulman EP, Aldape KD, Curran WJ, Mehta MP. A randomized trial of bevacizumab for newly diagnosed glioblastoma. N Engl J Med. 2014 Feb 20; 370(8):699-708. PMID: 24552317; PMCID: PMC4201043.
      Citations: 1076     Fields:    Translation:HumansCTClinical Trials
    156. Verma J, Sulman EP, Jhingran A, Tucker SL, Rauch GM, Eifel PJ, Klopp AH. Dosimetric predictors of duodenal toxicity after intensity modulated radiation therapy for treatment of the para-aortic nodes in gynecologic cancer. Int J Radiat Oncol Biol Phys. 2014 Feb 01; 88(2):357-62. PMID: 24411609.
      Citations: 21     Fields:    Translation:HumansPHPublic Health
    157. Saito N, Fu J, Zheng S, Yao J, Wang S, Liu DD, Yuan Y, Sulman EP, Lang FF, Colman H, Verhaak RG, Yung WK, Koul D. A high Notch pathway activation predicts response to ? secretase inhibitors in proneural subtype of glioma tumor-initiating cells. Stem Cells. 2014 Jan; 32(1):301-12. PMID: 24038660; PMCID: PMC3947402.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    158. Beiko J, Suki D, Hess KR, Fox BD, Cheung V, Cabral M, Shonka N, Gilbert MR, Sawaya R, Prabhu SS, Weinberg J, Lang FF, Aldape KD, Sulman EP, Rao G, McCutcheon IE, Cahill DP. IDH1 mutant malignant astrocytomas are more amenable to surgical resection and have a survival benefit associated with maximal surgical resection. Neuro Oncol. 2014 Jan; 16(1):81-91. PMID: 24305719; PMCID: PMC3870823.
      Citations: 161     Fields:    Translation:Humans
    159. Lichti CF, Liu H, Shavkunov AS, Mostovenko E, Sulman EP, Ezhilarasan R, Wang Q, Kroes RA, Moskal JC, Conrad CA, Lang FF, Berven FS, Rezeli M, Hober S, Nilsson CL, Feny? D, Oksuz BA, V?gv?ri A, Marko-Varga G. Integrated chromosome 19 transcriptomic and proteomic data sets derived from glioma cancer stem-cell lines. J Proteome Res. 2014 Jan 03; 13(1):191-9. PMID: 24266786.
      Citations: 10     Fields:    Translation:HumansCells
    160. Bhat KPL, Balasubramaniyan V, Vaillant B, Ezhilarasan R, Hummelink K, Hollingsworth F, Wani K, Heathcock L, James JD, Goodman LD, Conroy S, Long L, Lelic N, Wang S, Gumin J, Raj D, Kodama Y, Raghunathan A, Olar A, Joshi K, Pelloski CE, Heimberger A, Kim SH, Cahill DP, Rao G, Den Dunnen WFA, Boddeke HWGM, Phillips HS, Nakano I, Lang FF, Colman H, Sulman EP, Aldape K. Mesenchymal differentiation mediated by NF-?B promotes radiation resistance in glioblastoma. Cancer Cell. 2013 Sep 09; 24(3):331-46. PMID: 23993863; PMCID: PMC3817560.
      Citations: 479     Fields:    Translation:HumansAnimalsCells
    161. Piao Y, Liang J, Holmes L, Henry V, Sulman E, de Groot JF. Acquired resistance to anti-VEGF therapy in glioblastoma is associated with a mesenchymal transition. Clin Cancer Res. 2013 Aug 15; 19(16):4392-403. PMID: 23804423.
      Citations: 92     Fields:    Translation:HumansAnimalsCells
    162. Zheng S, Fu J, Vegesna R, Mao Y, Heathcock LE, Torres-Garcia W, Ezhilarasan R, Wang S, McKenna A, Chin L, Brennan CW, Yung WK, Weinstein JN, Aldape KD, Sulman EP, Chen K, Koul D, Verhaak RG. A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival. Genes Dev. 2013 Jul 01; 27(13):1462-72. PMID: 23796897; PMCID: PMC3713427.
      Citations: 43     Fields:    Translation:Animals
    163. Tsai CJ, Sulman EP, Eifel PJ, Jhingran A, Allen PK, Deavers MT, Klopp AH. Galectin-7 levels predict radiation response in squamous cell carcinoma of the cervix. Gynecol Oncol. 2013 Dec; 131(3):645-9. PMID: 23643871.
      Citations: 13     Fields:    Translation:Humans
    164. Fu J, Koul D, Yao J, Wang S, Yuan Y, Colman H, Sulman EP, Lang FF, Yung WK. Novel HSP90 inhibitor NVP-HSP990 targets cell-cycle regulators to ablate Olig2-positive glioma tumor-initiating cells. Cancer Res. 2013 May 15; 73(10):3062-74. PMID: 23492364; PMCID: PMC3655088.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    165. Holliday EB, Sulman EP. Tumor prognostic factors and the challenge of developing predictive factors. Curr Oncol Rep. 2013 Feb; 15(1):33-46. PMID: 23224629.
      Citations: 1     Fields:    Translation:Humans
    166. Welsh JW, Komaki R, Amini A, Munsell MF, Unger W, Allen PK, Chang JY, Wefel JS, McGovern SL, Garland LL, Chen SS, Holt J, Liao Z, Brown P, Sulman E, Heymach JV, Kim ES, Stea B. Phase II trial of erlotinib plus concurrent whole-brain radiation therapy for patients with brain metastases from non-small-cell lung cancer. J Clin Oncol. 2013 Mar 01; 31(7):895-902. PMID: 23341526; PMCID: PMC3577951.
      Citations: 177     Fields:    Translation:HumansCTClinical Trials
    167. Nilsson CL, Berven F, Selheim F, Liu H, Moskal JR, Kroes RA, Sulman EP, Conrad CA, Lang FF, Nilsson A, Carlsohn E, Lilja H, Malm J, Subramaniyam D, Wang X, Gonzales-Gonzales M, Dasilva N, Diez P, Fuentes M, Welinder C, Laurell T, Fehniger TE, Lindberg H, Rezeli M, Edula G, Hober S, Andr?n PE, Feny? D, V?gv?ri ?, Sj?din K, Marko-Varga G. Chromosome 19 annotations with disease speciation: a first report from the Global Research Consortium. J Proteome Res. 2013 Jan 04; 12(1):135-50. PMID: 23249167; PMCID: PMC3539432.
      Citations: 5     Fields:    Translation:HumansCells
    168. Niola F, Zhao X, Singh D, Sullivan R, Castano A, Verrico A, Zoppoli P, Friedmann-Morvinski D, Sulman E, Barrett L, Zhuang Y, Verma I, Benezra R, Aldape K, Iavarone A, Lasorella A. Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis. J Clin Invest. 2013 Jan; 123(1):405-17. PMID: 23241957; PMCID: PMC3537192.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    169. Likhacheva A, Pinnix CC, Parikh N, Allen PK, Guha-Thakurta N, McAleer M, Sulman EP, Mahajan A, Shiu A, Luo D, Chiu M, Brown PD, Prabhu SS, Chang EL. Validation of Recursive Partitioning Analysis and Diagnosis-Specific Graded Prognostic Assessment in patients treated initially with radiosurgery alone. J Neurosurg. 2012 Dec; 117 Suppl:38-44. PMID: 23205787; PMCID: PMC3910154.
      Citations: 16     Fields:    Translation:Humans
    170. Debeb BG, Lacerda L, Xu W, Larson R, Solley T, Atkinson R, Sulman EP, Ueno NT, Krishnamurthy S, Reuben JM, Buchholz TA, Woodward WA. Histone deacetylase inhibitors stimulate dedifferentiation of human breast cancer cells through WNT/?-catenin signaling. Stem Cells. 2012 Nov; 30(11):2366-77. PMID: 22961641; PMCID: PMC4545658.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    171. Likhacheva A, Pinnix CC, Parikh NR, Allen PK, McAleer MF, Chiu MS, Sulman EP, Mahajan A, Guha-Thakurta N, Prabhu SS, Cahill DP, Luo D, Shiu AS, Brown PD, Chang EL. Predictors of survival in contemporary practice after initial radiosurgery for brain metastases. Int J Radiat Oncol Biol Phys. 2013 Mar 01; 85(3):656-61. PMID: 22898384.
      Citations: 34     Fields:    Translation:Humans
    172. Koay E, Sulman EP. Management of brain metastasis: past lessons, modern management, and future considerations. Curr Oncol Rep. 2012 Feb; 14(1):70-8. PMID: 22071681.
      Citations: 15     Fields:    Translation:Humans
    173. Li J, Sulman E, Aldape K. Molecular biology of brain tumors. Handb Clin Neurol. 2012; 104:23-34. PMID: 22230432.
      Citations: 2     Fields:    Translation:Humans
    174. Bhat KP, Salazar KL, Balasubramaniyan V, Wani K, Heathcock L, Hollingsworth F, James JD, Gumin J, Diefes KL, Kim SH, Turski A, Azodi Y, Yang Y, Doucette T, Colman H, Sulman EP, Lang FF, Rao G, Copray S, Vaillant BD, Aldape KD. The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma. Genes Dev. 2011 Dec 15; 25(24):2594-609. PMID: 22190458; PMCID: PMC3248681.
      Citations: 203     Fields:    Translation:HumansAnimalsCells
    175. Pinnix CC, Fontanilla HP, Hayes-Jordan A, Subbiah V, Bilton SD, Chang EL, Grosshans DR, McAleer MF, Sulman EP, Woo SY, Anderson P, Green HL, Mahajan A. Whole abdominopelvic intensity-modulated radiation therapy for desmoplastic small round cell tumor after surgery. Int J Radiat Oncol Biol Phys. 2012 May 01; 83(1):317-26. PMID: 22104361; PMCID: PMC4005898.
      Citations: 19     Fields:    Translation:Humans
    176. Miller CA, Settle SH, Sulman EP, Aldape KD, Milosavljevic A. Discovering functional modules by identifying recurrent and mutually exclusive mutational patterns in tumors. BMC Med Genomics. 2011 Apr 14; 4:34. PMID: 21489305; PMCID: PMC3102606.
      Citations: 64     Fields:    Translation:HumansCells
    177. de Groot JF, Sulman EP, Aldape KD. Multigene sets for clinical application in glioma. J Natl Compr Canc Netw. 2011 Apr; 9(4):449-56; quiz 457. PMID: 21464148.
      Citations: 1     Fields:    Translation:HumansCells
    178. Settle SH, Sulman EP. Tumor profiling: development of prognostic and predictive factors to guide brain tumor treatment. Curr Oncol Rep. 2011 Feb; 13(1):26-36. PMID: 21082294.
      Citations: 1     Fields:    Translation:Humans
    179. Sulman EP, Aldape K. The use of global profiling in biomarker development for gliomas. Brain Pathol. 2011 Jan; 21(1):88-95. PMID: 21129062; PMCID: PMC8094258.
      Citations: 13     Fields:    Translation:Humans
    180. Bonato V, Baladandayuthapani V, Broom BM, Sulman EP, Aldape KD, Do KA. Bayesian ensemble methods for survival prediction in gene expression data. Bioinformatics. 2011 Feb 01; 27(3):359-67. PMID: 21148161; PMCID: PMC3031034.
      Citations: 24     Fields:    Translation:Humans
    181. Noushmehr H, Weisenberger DJ, Diefes K, Phillips HS, Pujara K, Berman BP, Pan F, Pelloski CE, Sulman EP, Bhat KP, Verhaak RG, Hoadley KA, Hayes DN, Perou CM, Schmidt HK, Ding L, Wilson RK, Van Den Berg D, Shen H, Bengtsson H, Neuvial P, Cope LM, Buckley J, Herman JG, Baylin SB, Laird PW, Aldape K, Cancer Genome Atlas Research Network. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell. 2010 May 18; 17(5):510-22. PMID: 20399149; PMCID: PMC2872684.
      Citations: 1124     Fields:    Translation:HumansCells
    182. Broom BM, Sulman EP, Do KA, Edgerton ME, Kenneth D. Aldape. Bagged gene shaving for the robust clustering of high-throughput data. Int J Bioinform Res Appl. 2010; 6(4):326-43. PMID: 20940121; PMCID: PMC3879957.
      Citations: 3     Fields:    
    183. Carro MS, Lim WK, Alvarez MJ, Bollo RJ, Zhao X, Snyder EY, Sulman EP, Anne SL, Doetsch F, Colman H, Lasorella A, Aldape K, Califano A, Iavarone A. The transcriptional network for mesenchymal transformation of brain tumours. Nature. 2010 Jan 21; 463(7279):318-25. PMID: 20032975; PMCID: PMC4011561.
      Citations: 651     Fields:    Translation:HumansAnimalsCells
    184. Rivera AL, Pelloski CE, Gilbert MR, Colman H, De La Cruz C, Sulman EP, Bekele BN, Aldape KD. MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma. Neuro Oncol. 2010 Feb; 12(2):116-21. PMID: 20150378; PMCID: PMC2940581.
      Citations: 158     Fields:    Translation:HumansCells
    185. Colman H, Zhang L, Sulman EP, McDonald JM, Shooshtari NL, Rivera A, Popoff S, Nutt CL, Louis DN, Cairncross JG, Gilbert MR, Phillips HS, Mehta MP, Chakravarti A, Pelloski CE, Bhat K, Feuerstein BG, Jenkins RB, Aldape K. A multigene predictor of outcome in glioblastoma. Neuro Oncol. 2010 Jan; 12(1):49-57. PMID: 20150367; PMCID: PMC2940562.
      Citations: 184     Fields:    Translation:Humans
    186. Sulman EP, Guerrero M, Aldape K. Beyond grade: molecular pathology of malignant gliomas. Semin Radiat Oncol. 2009 Jul; 19(3):142-9. PMID: 19464628.
      Citations: 20     Fields:    Translation:Humans
    187. Sulman EP, Komaki R, Klopp AH, Cox JD, Chang JY. Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer. Radiat Oncol. 2009 Jan 30; 4:5. PMID: 19183471; PMCID: PMC2651897.
      Citations: 27     Fields:    Translation:Humans
    188. Woodward WA, Sulman EP. Cancer stem cells: markers or biomarkers? Cancer Metastasis Rev. 2008 Sep; 27(3):459-70. PMID: 18437295.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    189. Sulman EP, Schwartz DL, Le TT, Ang KK, Morrison WH, Rosenthal DI, Ahamad A, Kies M, Glisson B, Weber R, Garden AS. IMRT reirradiation of head and neck cancer-disease control and morbidity outcomes. Int J Radiat Oncol Biol Phys. 2009 Feb 01; 73(2):399-409. PMID: 18556144.
      Citations: 55     Fields:    Translation:Humans
    190. Rivera AL, Pelloski CE, Sulman E, Aldape K. Prognostic and predictive markers in glioma and other neuroepithelial tumors. Curr Probl Cancer. 2008 May-Jun; 32(3):97-123. PMID: 18501774.
      Citations: 5     Fields:    Translation:Humans
    191. Sulman E, Aldape K, Colman H. Brain tumor stem cells. Curr Probl Cancer. 2008 May-Jun; 32(3):124-42. PMID: 18501775.
      Citations: 9     Fields:    Translation:HumansCells
    192. Klopp AH, Chang JY, Tucker SL, Sulman EP, Balter PA, Liu HH, Bucci MK, Macapinlac HA, Komaki R, Cox JD. Intrathoracic patterns of failure for non-small-cell lung cancer with positron-emission tomography/computed tomography-defined target delineation. Int J Radiat Oncol Biol Phys. 2007 Dec 01; 69(5):1409-16. PMID: 17904303.
      Citations: 6     Fields:    Translation:Humans
    193. Pelloski CE, Ballman KV, Furth AF, Zhang L, Lin E, Sulman EP, Bhat K, McDonald JM, Yung WK, Colman H, Woo SY, Heimberger AB, Suki D, Prados MD, Chang SM, Barker FG, Buckner JC, James CD, Aldape K. Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma. J Clin Oncol. 2007 Jun 01; 25(16):2288-94. PMID: 17538175.
      Citations: 121     Fields:    Translation:Humans
    194. Sulman EP, White PS, Brodeur GM. Genomic annotation of the meningioma tumor suppressor locus on chromosome 1p34. Oncogene. 2004 Jan 29; 23(4):1014-20. PMID: 14749765.
      Citations: 16     Fields:    Translation:HumansCells
    195. Matise TC, Porter CJ, Buyske S, Cuttichia AJ, Sulman EP, White PS. Systematic evaluation of map quality: human chromosome 22. Am J Hum Genet. 2002 Jun; 70(6):1398-410. PMID: 11992248; PMCID: PMC379125.
      Citations: 5     Fields:    Translation:HumansCells
    196. Maris JM, Guo C, Blake D, White PS, Hogarty MD, Thompson PM, Rajalingam V, Gerbing R, Stram DO, Matthay KK, Seeger RC, Brodeur GM. Comprehensive analysis of chromosome 1p deletions in neuroblastoma. Med Pediatr Oncol. 2001 Jan; 36(1):32-6. PMID: 11464900.
      Citations: 25     Fields:    Translation:HumansCells
    197. White PS, Thompson PM, Seifried BA, Sulman EP, Jensen SJ, Guo C, Maris JM, Hogarty MD, Allen C, Biegel JA, Matise TC, Gregory SG, Reynolds CP, Brodeur GM. Detailed molecular analysis of 1p36 in neuroblastoma. Med Pediatr Oncol. 2001 Jan; 36(1):37-41. PMID: 11464901.
      Citations: 18     Fields:    Translation:HumansCells
    198. Hogarty MD, Liu X, Guo C, Thompson PM, Weiss MJ, White PS, Sulman EP, Brodeur GM, Maris JM. Identification of a 1-megabase consensus region of deletion at 1p36.3 in primary neuroblastomas. Med Pediatr Oncol. 2000 Dec; 35(6):512-5. PMID: 11107105.
      Citations: 5     Fields:    Translation:HumansCells
    199. Hogarty MD, Liu X, Thompson PM, White PS, Sulman EP, Maris JM, Brodeur GM. BIN1 inhibits colony formation and induces apoptosis in neuroblastoma cell lines with MYCN amplification. Med Pediatr Oncol. 2000 Dec; 35(6):559-62. PMID: 11107117.
      Citations: 8     Fields:    Translation:HumansCells
    200. Maris JM, Weiss MJ, Guo C, Gerbing RB, Stram DO, White PS, Hogarty MD, Sulman EP, Thompson PM, Lukens JN, Matthay KK, Seeger RC, Brodeur GM. Loss of heterozygosity at 1p36 independently predicts for disease progression but not decreased overall survival probability in neuroblastoma patients: a Children's Cancer Group study. J Clin Oncol. 2000 May; 18(9):1888-99. PMID: 10784629.
      Citations: 47     Fields:    Translation:HumansCells
    201. White PS, Sulman EP, Porter CJ, Matise TC. A comprehensive view of human chromosome 1. Genome Res. 1999 Oct; 9(10):978-88. PMID: 10523526; PMCID: PMC310818.
      Citations: 2     Fields:    Translation:HumansCells
    202. Hogarty MD, White PS, Sulman EP, Brodeur GM. Mononucleotide repeat instability is infrequent in neuroblastoma. Cancer Genet Cytogenet. 1998 Oct 15; 106(2):140-3. PMID: 9797779.
      Citations:    Fields:    Translation:HumansCells
    203. Sulman EP, Dumanski JP, White PS, Zhao H, Maris JM, Mathiesen T, Bruder C, Cnaan A, Brodeur GM. Identification of a consistent region of allelic loss on 1p32 in meningiomas: correlation with increased morbidity. Cancer Res. 1998 Aug 01; 58(15):3226-30. PMID: 9699646.
      Citations: 20     Fields:    Translation:HumansCells
    204. White PS, Jensen SJ, Rajalingam V, Stairs D, Sulman EP, Maris JM, Biegel JA, Wooster R, Brodeur GM. Physical mapping of the CA6, ENO1, and SLC2A5 (GLUT5) genes and reassignment of SLC2A5 to 1p36.2. Cytogenet Cell Genet. 1998; 81(1):60-4. PMID: 9691177.
      Citations: 1     Fields:    Translation:HumansCells
    205. Maris JM, Jensen J, Sulman EP, Beltinger CP, Allen C, Biegel JA, Brodeur GM, White PS. Human Kr?ppel-related 3 (HKR3): a candidate for the 1p36 neuroblastoma tumour suppressor gene? Eur J Cancer. 1997 Oct; 33(12):1991-6. PMID: 9516840.
      Citations: 10     Fields:    Translation:HumansCells
    206. White PS, Maris JM, Sulman EP, Jensen SJ, Kyemba SM, Beltinger CP, Allen C, Kramer DL, Biegel JA, Brodeur GM. Molecular analysis of the region of distal 1p commonly deleted in neuroblastoma. Eur J Cancer. 1997 Oct; 33(12):1957-61. PMID: 9516832.
      Citations: 11     Fields:    Translation:HumansCells
    207. Maris JM, Kyemba SM, Rebbeck TR, White PS, Sulman EP, Jensen SJ, Allen C, Biegel JA, Brodeur GM. Molecular genetic analysis of familial neuroblastoma. Eur J Cancer. 1997 Oct; 33(12):1923-8. PMID: 9516825.
      Citations: 14     Fields:    Translation:HumansCells
    208. Jensen SJ, Sulman EP, Maris JM, Matise TC, Vojta PJ, Barrett JC, Brodeur GM, White PS. An integrated transcript map of human chromosome 1p35-p36. Genomics. 1997 May 15; 42(1):126-36. PMID: 9177782.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    209. Reddy UR, Phatak S, Allen C, Nycum LM, Sulman EP, White PS, Biegel JA. Localization of the human Ror1 gene (NTRKR1) to chromosome 1p31-p32 by fluorescence in situ hybridization and somatic cell hybrid analysis. Genomics. 1997 Apr 15; 41(2):283-5. PMID: 9143508.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    210. Sulman EP, Tang XX, Allen C, Biegel JA, Pleasure DE, Brodeur GM, Ikegaki N. ECK, a human EPH-related gene, maps to 1p36.1, a common region of alteration in human cancers. Genomics. 1997 Mar 01; 40(2):371-4. PMID: 9119409.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    211. Kuroda H, White PS, Sulman EP, Manohar CF, Reiter JL, Cohn SL, Brodeur GM. Physical mapping of the DDX1 gene to 340 kb 5' of MYCN. Oncogene. 1996 Oct 03; 13(7):1561-5. PMID: 8875996.
      Citations: 5     Fields:    Translation:HumansCells
    212. Maris JM, Kyemba SM, Rebbeck TR, White PS, Sulman EP, Jensen SJ, Allen C, Biegel JA, Yanofsky RA, Feldman GL, Brodeur GM. Familial predisposition to neuroblastoma does not map to chromosome band 1p36. Cancer Res. 1996 Aug 01; 56(15):3421-5. PMID: 8758905.
      Citations: 9     Fields:    Translation:HumansCells
    213. Maris JM, Jensen SJ, Sulman EP, Beltinger CP, Gates K, Allen C, Biegel JA, Brodeur GM, White PS. Cloning, chromosomal localization, physical mapping, and genomic characterization of HKR3. Genomics. 1996 Jul 15; 35(2):289-98. PMID: 8661141.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    214. Beltinger CP, White PS, Maris JM, Sulman EP, Jensen SJ, LePaslier D, Stallard BJ, Goeddel DV, de Sauvage FJ, Brodeur GM. Physical mapping and genomic structure of the human TNFR2 gene. Genomics. 1996 Jul 01; 35(1):94-100. PMID: 8661109.
      Citations: 15     Fields:    Translation:HumansCells
    215. Ikegaki N, Tang XX, Liu XG, Biegel JA, Allen C, Yoshioka A, Sulman EP, Brodeur GM, Pleasure DE. Molecular characterization and chromosomal localization of DRT (EPHT3): a developmentally regulated human protein-tyrosine kinase gene of the EPH family. Hum Mol Genet. 1995 Nov; 4(11):2033-45. PMID: 8589679.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    216. Maris JM, White PS, Beltinger CP, Sulman EP, Castleberry RP, Shuster JJ, Look AT, Brodeur GM. Significance of chromosome 1p loss of heterozygosity in neuroblastoma. Cancer Res. 1995 Oct 15; 55(20):4664-9. PMID: 7553646.
      Citations: 33     Fields:    Translation:HumansCells
    217. White PS, Maris JM, Beltinger C, Sulman E, Marshall HN, Fujimori M, Kaufman BA, Biegel JA, Allen C, Hilliard C, Valentine MB, Look AT, Enomoto H, Sakiyama S, Brodeur GM. A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3. Proc Natl Acad Sci U S A. 1995 Jun 06; 92(12):5520-4. PMID: 7777541; PMCID: PMC41727.
      Citations: 56     Fields:    Translation:HumansCells
    218. Beltinger CP, White PS, Sulman EP, Maris JM, Brodeur GM. No CDKN2 mutations in neuroblastomas. Cancer Res. 1995 May 15; 55(10):2053-5. PMID: 7743501.
      Citations: 3     Fields:    Translation:HumansCells
    219. SULMAN E, SULMAN F. The carcinogenicity of wood soot from the chimney of a smoked sausage factory. Cancer Res. 1946 Jul; 6:366. PMID: 20987096.
      Citations: 1     Fields:    Translation:HumansAnimals
    220. Erratum. Journal of Clinical Investigation. 124:4134.
    221. Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth. Cell. 167:1281-1295.e18.
    222. Suppression of RAF/MEK or PI3K synergizes cytotoxicity of receptor tyrosine kinase inhibitors in glioma tumor-initiating cells. Journal of Translational Medicine.
    223. The proteomic landscape of glioma stem-like cells. EuPA Open Proteomics. 8:85-93.
    224. Mir-21-Sox2 axis delineates glioblastoma subtypes with prognostic impact. Journal of Neuroscience. 35:15097-15112.
    225. Genetic modulation of neurocognitive function in glioma patients. Clinical Cancer Research. 21:3340-3346.
    226. Aberrant mesenchymal differentiation of glioma stem-like cells. Oncotarget. 6:31007-31017.
    227. Molecular markers in low-grade glioma-toward tumor reclassification. Seminars in Radiation Oncology. 25:155-163.
    228. A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Nature Communications. 7.
    229. Mitotic index is an independent predictor of recurrence-free survival in meningioma. Brain Pathology. 25:266-275.
    230. Mesenchymal Stem Cells Isolated from Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 Pathway. Stem Cells. 33:2400-2415.
    231. Delineation of MGMT Hypermethylation as a Biomarker for Veliparib-Mediated Temozolomide-Sensitizing Therapy of Glioblastoma. Journal of the National Cancer Institute. 108.
    232. Serine/Threonine Kinase MLK4 Determines Mesenchymal Identity in Glioma Stem Cells in an NF-κB-dependent Manner. Cancer Cell. 29:201-213.
    233. A randomized trial of bevacizumab for newly diagnosed glioblastoma. New England Journal of Medicine. 370:699-708.
    234. Effect of tumor subtype on survival and the graded prognostic assessment for patients with breast cancer and brain metastases. Breast Diseases. 24:175-176.
    235. A Dexamethasone-regulated Gene Signature Is Prognostic for Poor Survival in Glioblastoma Patients. Journal of Neurosurgical Anesthesiology.
    236. TERT Promoter Mutations and Risk of Recurrence in Meningioma. Journal of the National Cancer Institute. 108.
    237. Systematic identification of single amino acid variants in glioma stem-cell-derived chromosome 19 proteins. Journal of Proteome Research. 14:778-786.
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