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CROWE, JAMES

One or more keywords matched the following items that are connected to CROWE, JAMES

Item Type	Name
Academic Article	Identification of a novel human leucocyte antigen-A*01-restricted cytotoxic T-lymphocyte epitope in the respiratory syncytial virus fusion protein.
Academic Article	Generation of recombinant human monoclonal antibodies to rotavirus from single antigen-specific B cells selected with fluorescent virus-like particles.
Academic Article	Pseudovirion particle production by live poxvirus human immunodeficiency virus vaccine vector enhances humoral and cellular immune responses.
Academic Article	Natural evolution of a human virus-specific antibody gene repertoire by somatic hypermutation requires both hotspot-directed and randomly-directed processes.
Academic Article	The transmembrane domain of the respiratory syncytial virus F protein is an orientation-independent apical plasma membrane sorting sequence.
Academic Article	Cellular immune responses to diluted and undiluted aventis pasteur smallpox vaccine.
Academic Article	Infant and adult human B cell responses to rotavirus share common immunodominant variable gene repertoires.
Academic Article	VH1-46 is the dominant immunoglobulin heavy chain gene segment in rotavirus-specific memory B cells expressing the intestinal homing receptor alpha4beta7.
Academic Article	Identification of an H-2D(b)-restricted CD8+ cytotoxic T lymphocyte epitope in the matrix protein of respiratory syncytial virus.
Academic Article	Homing in on acute graft vs. host disease: tissue-specific T regulatory and Th17 cells.
Academic Article	Transforming growth factor beta is a major regulator of human neonatal immune responses following respiratory syncytial virus infection.
Academic Article	Predicting posttransplantation diabetes mellitus by regulatory T-cell phenotype: implications for metabolic intervention to modulate alloreactivity.
Academic Article	Towards a consensus on datasets and evaluation metrics for developing B-cell epitope prediction tools.
Academic Article	Respiratory syncytial virus regulates human microRNAs by using mechanisms involving beta interferon and NF-?B.
Academic Article	Discovering naturally processed antigenic determinants that confer protective T cell immunity.
Academic Article	Transcriptional control of activation-induced cytidine deaminase and error-prone DNA polymerases is functionally mature in the B cells of infants at birth.
Academic Article	Low expression of the interleukin (IL)-4 receptor alpha chain and reduced signalling via the IL-4 receptor complex in human neonatal B cells.
Academic Article	Immunodominance of the VH1-46 antibody gene segment in the primary repertoire of human rotavirus-specific B cells is reduced in the memory compartment through somatic mutation of nondominant clones.
Academic Article	An optimized electrofusion-based protocol for generating virus-specific human monoclonal antibodies.
Academic Article	Single molecule-sensitive probes for imaging RNA in live cells.
Academic Article	Pseudovirion particles bearing native HIV envelope trimers facilitate a novel method for generating human neutralizing monoclonal antibodies against HIV.
Academic Article	Human respiratory syncytial virus nucleoprotein and inclusion bodies antagonize the innate immune response mediated by MDA5 and MAVS.
Academic Article	Maturation-induced cloaking of neutralization epitopes on HIV-1 particles.
Academic Article	Persistence of circulating memory B cell clones with potential for dengue virus disease enhancement for decades following infection.
Academic Article	Respiratory syncytial virus nucleoprotein-specific cytotoxic T-cell epitopes in a South African population of diverse HLA types are conserved in circulating field strains.
Academic Article	Apical recycling systems regulate directional budding of respiratory syncytial virus from polarized epithelial cells.
Academic Article	Differential regulation of granzyme and perforin in effector and memory T cells following smallpox immunization.
Academic Article	Rotavirus-specific CD5+ B cells in young children exhibit a distinct antibody repertoire compared with CD5- B cells.
Academic Article	Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infection.
Academic Article	Evidence for preferential Ig gene usage and differential TdT and exonuclease activities in human na?ve and memory B cells.
Academic Article	Enhancement of the CD8+ T cell response to a subdominant epitope of respiratory syncytial virus by deletion of an immunodominant epitope.
Academic Article	Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors.
Academic Article	The human neonatal B cell response to respiratory syncytial virus uses a biased antibody variable gene repertoire that lacks somatic mutations.
Academic Article	Emerging studies of human HIV-specific antibody repertoires.
Academic Article	Respiratory syncytial virus induces host RNA stress granules to facilitate viral replication.
Academic Article	Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence.
Academic Article	Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions.
Academic Article	Frequency and genetic characterization of V(DD)J recombinants in the human peripheral blood antibody repertoire.
Academic Article	Tissue-specific regulatory T cells: biomarker for acute graft-vs-host disease and survival.
Academic Article	Human monoclonal antibodies derived from memory B cells following live attenuated dengue virus vaccination or natural infection exhibit similar characteristics.
Academic Article	Human rotavirus VP6-specific antibodies mediate intracellular neutralization by binding to a quaternary structure in the transcriptional pore.
Concept	Jurkat Cells
Concept	Vero Cells
Concept	Epithelial Cells
Concept	T-Lymphocytes, Cytotoxic
Concept	Megakaryocyte-Erythroid Progenitor Cells
Concept	HeLa Cells
Concept	Dendritic Cells
Concept	Gene Rearrangement, B-Lymphocyte, Heavy Chain
Concept	Clone Cells
Concept	K562 Cells
Concept	Th1 Cells
Concept	CD8-Positive T-Lymphocytes
Concept	B-Lymphocyte Subsets
Concept	Germ Cells
Concept	CHO Cells
Concept	T-Lymphocytes, Regulatory
Concept	CD4-Positive T-Lymphocytes
Concept	Antigen-Presenting Cells
Concept	Th2 Cells
Concept	B-Lymphocytes
Concept	3T3 Cells
Concept	Tumor Cells, Cultured
Concept	Bone Marrow Cells
Concept	Receptors, Antigen, B-Cell
Concept	Killer Cells, Natural
Concept	Anterior Horn Cells
Concept	Cells, Cultured
Concept	Caco-2 Cells
Concept	Epitopes, B-Lymphocyte
Concept	T-Lymphocytes
Academic Article	Gold nanorod vaccine for respiratory syncytial virus.
Academic Article	Impact of new sequencing technologies on studies of the human B cell repertoire.
Academic Article	The potent and broadly neutralizing human dengue virus-specific monoclonal antibody 1C19 reveals a unique cross-reactive epitope on the bc loop of domain II of the envelope protein.
Academic Article	Combining single RNA sensitive probes with subdiffraction-limited and live-cell imaging enables the characterization of virus dynamics in cells.
Academic Article	Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity.
Academic Article	Tissue-specific expressed antibody variable gene repertoires.
Academic Article	STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge.
Academic Article	Isolation of dengue virus-specific memory B cells with live virus antigen from human subjects following natural infection reveals the presence of diverse novel functional groups of antibody clones.
Academic Article	A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins.
Academic Article	Mechanism of human antibody-mediated neutralization of Marburg virus.
Academic Article	Spleen Tyrosine Kinase (Syk) Mediates IL-1? Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection.
Academic Article	Use of Human Hybridoma Technology To Isolate Human Monoclonal Antibodies.
Academic Article	Association of VH4-59 Antibody Variable Gene Usage with Recognition of an Immunodominant Epitope on the HIV-1 Gag Protein.
Academic Article	Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1? Secretion: A Primary Human Monocyte Model.
Academic Article	Low frequency of broadly neutralizing HIV antibodies during chronic infection even in quaternary epitope targeting antibodies containing large numbers of somatic mutations.
Academic Article	Early Th1 immunity promotes immune tolerance and may impair graft-versus-leukemia effect after allogeneic hematopoietic cell transplantation.
Academic Article	Chimeric Filoviruses for Identification and Characterization of Monoclonal Antibodies.
Academic Article	Characterization of dengue virus 2 growth in megakaryocyte-erythrocyte progenitor cells.
Academic Article	Deep sequencing and human antibody repertoire analysis.
Academic Article	Frequent Use of the IgA Isotype in Human B Cells Encoding Potent Norovirus-Specific Monoclonal Antibodies That Block HBGA Binding.
Academic Article	Human Antibodies that Recognize Novel Immunodominant Quaternary Epitopes on the HIV-1 Env Protein.
Academic Article	Pathogenic Chikungunya Virus Evades B Cell Responses to Establish Persistence.
Academic Article	Development of Human Monoclonal Antibodies Against Respiratory Syncytial Virus Using a High Efficiency Human Hybridoma Technique.
Academic Article	Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice.
Academic Article	Mapping the Human Memory B Cell and Serum Neutralizing Antibody Responses to Dengue Virus Serotype 4 Infection and Vaccination.
Academic Article	Monoclonal Antibodies Against the Staphylococcus aureus Bicomponent Leukotoxin AB Isolated Following Invasive Human Infection Reveal Diverse Binding and Modes of Action.
Academic Article	A human antibody against Zika virus crosslinks the E protein to prevent infection.
Academic Article	Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques.
Academic Article	Synergistic anti-HCV broadly neutralizing human monoclonal antibodies with independent mechanisms.
Academic Article	Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans.
Academic Article	Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus.
Academic Article	The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding.
Academic Article	Broadly neutralizing antibodies from human survivors target a conserved site in the Ebola virus glycoprotein HR2-MPER region.
Academic Article	Ebolavirus Chimerization for the Development of a Mouse Model for Screening of Bundibugyo-Specific Antibodies.
Academic Article	Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors.
Academic Article	Mxra8 is a receptor for multiple arthritogenic alphaviruses.
Academic Article	Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein.
Academic Article	A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus.
Academic Article	In?Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model.
Academic Article	High frequency of shared clonotypes in human B cell receptor repertoires.
Academic Article	Antibody Determinants of Influenza Immunity.
Academic Article	Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains.
Academic Article	Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody.
Academic Article	Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth.
Academic Article	Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection.
Academic Article	Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein.
Academic Article	A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions.
Academic Article	Influenza Virus-Specific Human Antibody Repertoire Studies.
Grant	Rotavirus VP6 Specific Human IgA Antibodies
Grant	Immunomodulation on the Nanoscale (RMI)
Grant	Cell-Mediated Immune Responses to Vaccinia Viruses
Grant	Human T Cells Responses to RSV
Grant	ONTOGENY OF RSV-SPECIFIC B CELL RESPONSES IN HUMANS
Grant	ONTOGENY OF RSV-SPECIFIC B CELL RESPONSES IN HUMANS
Grant	Molecular Determinants of Cross-Reactive Antibody Response to Influenza in Humans
Grant	Human neutralizing monoclonal antibodies for Rift Valley fever virus
Grant	HUMAN MONOCLONAL ANTIBODIES THAT NEUTRALIZE VACCINIA
Grant	Multi-Laser Flow Cytometer for Polychromatic Analysis
Grant	Clonal Analysis of the Human B Cell Response to HIV
Grant	Epitope Specificity of RSV Nucleoprotein-Specific T Cel*
Grant	High Throughput Flow Cytometry Sorter
Grant	RESPIRATORY VIRUS NEUTRALIZATION BY INTRACELLULAR AB
Academic Article	Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice.
Academic Article	Early Human B Cell Response to Ebola Virus in Four U.S. Survivors of Infection.
Academic Article	Broadly Neutralizing Antibodies Targeting New Sites of Vulnerability in Hepatitis C Virus E1E2.
Concept	RAW 264.7 Cells
Concept	THP-1 Cells
Concept	HEK293 Cells
Concept	Th17 Cells
Concept	Madin Darby Canine Kidney Cells
Concept	Sf9 Cells
Academic Article	A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface.
Academic Article	A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection.
Academic Article	Ehrlichia chaffeensis Outer Membrane Protein 1-Specific Human Antibody-Mediated Immunity Is Defined by Intracellular TRIM21-Dependent Innate Immune Activation and Extracellular Neutralization.
Academic Article	Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8+ Lung-Resident Memory T Cells.
Academic Article	Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge.
Academic Article	Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies.
Academic Article	Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease.
Academic Article	Identification of Dengue Virus Serotype 3 Specific Antigenic Sites Targeted by Neutralizing Human Antibodies.
Academic Article	Human-likeness of antibody biologics determined by back-translation and comparison with large antibody variable gene repertoires.
Academic Article	Computationally Designed Cyclic Peptides Derived from an Antibody Loop Increase Breadth of Binding for Influenza Variants.
Academic Article	Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease.
Academic Article	Diverse patterns of antibody variable gene repertoire disruption in patients with amyloid light chain (AL) amyloidosis.
Academic Article	High Frequency of Shared Clonotypes in Human T Cell Receptor Repertoires.
Academic Article	Potently neutralizing and protective human antibodies against SARS-CoV-2.
Academic Article	Humoral Immunity to Hantavirus Infection.
Academic Article	Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics.
Academic Article	Anti-influenza H7 human antibody targets antigenic site in hemagglutinin head domain interface.
Academic Article	Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Academic Article	Angiotensin-converting Enzyme 2-containing Small Extracellular Vesicles and Exomeres Bind the Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein.
Academic Article	Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19.
Academic Article	Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies.
Academic Article	Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection.
Academic Article	Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein.
Academic Article	Potent neutralization of Rift Valley fever virus by human monoclonal antibodies through fusion inhibition.
Academic Article	Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Academic Article	Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions.
Academic Article	In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains.
Academic Article	Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell.
Academic Article	Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope.
Academic Article	Cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein.
Academic Article	Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition.
Academic Article	Human Monoclonal Antibodies against NS1 Protein Protect against Lethal West Nile Virus Infection.
Academic Article	B cell overexpression of FCRL5 and PD-1 is associated with low antibody titers in HCV infection.
Academic Article	Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries.
Academic Article	Efficient discovery of SARS-CoV-2-neutralizing antibodies via B cell receptor sequencing and ligand blocking.
Academic Article	Enterovirus D68 in the Anterior Horn Cells of a Child with Acute Flaccid Myelitis.
Academic Article	Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine.

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