Gene Rearrangement, B-Lymphocyte, Heavy Chain
"Gene Rearrangement, B-Lymphocyte, Heavy Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ordered rearrangement of B-lymphocyte variable gene regions of the IMMUNOGLOBULIN HEAVY CHAINS, thereby contributing to antibody diversity. It occurs during the first stage of differentiation of the IMMATURE B-LYMPHOCYTES.
| Descriptor ID |
D015326
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| MeSH Number(s) |
G05.344.401.501 G12.500.274.501
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| Concept/Terms |
Gene Rearrangement, B-Lymphocyte, Heavy Chain- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- B-Cell Heavy Chain Gene Rearrangement
- B-Lymphocyte Heavy Chain Gene Rearrangement
- B Cell Heavy Chain Gene Rearrangement
- B Lymphocyte Heavy Chain Gene Rearrangement
|
Below are MeSH descriptors whose meaning is more general than "Gene Rearrangement, B-Lymphocyte, Heavy Chain".
Below are MeSH descriptors whose meaning is more specific than "Gene Rearrangement, B-Lymphocyte, Heavy Chain".
This graph shows the total number of publications written about "Gene Rearrangement, B-Lymphocyte, Heavy Chain" by people in this website by year, and whether "Gene Rearrangement, B-Lymphocyte, Heavy Chain" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Rearrangement, B-Lymphocyte, Heavy Chain" by people in Profiles.
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Advances in the assessment of minimal residual disease in mantle cell lymphoma. J Hematol Oncol. 2020 09 24; 13(1):127.
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B-cell lymphomas with MYC/8q24 rearrangements and IGH@BCL2/t(14;18)(q32;q21): an aggressive disease with heterogeneous histology, germinal center B-cell immunophenotype and poor outcome. Mod Pathol. 2012 Jan; 25(1):145-56.
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The B cell antigen receptor in atypical chronic lymphocytic leukemia with t(14;19)(q32;q13) demonstrates remarkable stereotypy. Int J Cancer. 2011 Jun 01; 128(11):2759-64.
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A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value. Blood. 2010 Oct 14; 116(15):e56-65.
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Clonal relationship of extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue involving different sites. Am J Clin Pathol. 2010 Jul; 134(1):112-8.
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Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing. Proc Natl Acad Sci U S A. 2008 Sep 02; 105(35):13081-6.
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The role of rearrangement at the second Ig heavy chain locus in maintaining B cell tolerance to DNA. J Immunol. 2008 Jun 01; 180(11):7721-7.
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Primary cutaneous marginal zone B-cell lymphoma. Am J Clin Pathol. 2006 Jun; 125 Suppl:S38-49.
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Restricted kappa/lambda light chain ratio by flow cytometry in germinal center B cells in Hashimoto thyroiditis. Am J Clin Pathol. 2006 Jan; 125(1):42-8.
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Infant and adult human B cell responses to rotavirus share common immunodominant variable gene repertoires. J Immunol. 2003 Nov 01; 171(9):4680-8.