AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation.

AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation. Genes Dev. 2020 10 01; 34(19-20):1330-1344.

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subject areas

AMP-Activated Protein Kinases
Animals
Diabetes Mellitus, Type 2
Disease Models, Animal
Gene Expression Regulation
Gene Knock-In Techniques
Genotype
Hypoglycemic Agents
Inflammation
Mechanistic Target of Rapamycin Complex 1
Metabolism
Metformin
Mice
Phosphorylation
Regulatory-Associated Protein of mTOR
Signal Transduction
TOR Serine-Threonine Kinases

authors with profiles

ERIC VAN NOSTRAND
JEANINE VAN NOSTRAND