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Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry.
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Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry.
Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry. Nat Commun. 2020 08 26; 11(1):4268.
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PubMed
subject areas
Acrylamides
Adaptor Proteins, Signal Transducing
Cell Line
Cell Survival
Fluorescent Dyes
Half-Life
Humans
Intracellular Space
Ligands
Molecular Dynamics Simulation
Mutation
Organic Chemistry Phenomena
Protein Binding
Protein Interaction Domains and Motifs
Proteolysis
Ubiquitin-Protein Ligases
authors with profiles
XIAOLI QI
JIN WANG
CHANG GEON CHUNG