"Claudin-5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A claudin subtype that is found localized to TIGHT JUNCTIONS in VASCULAR ENDOTHELIAL CELLS. The protein was initially identified as one of several proteins which are deleted in VELOCARDIOFACIAL SYNDROME and may play an important role in maintaining the integrity of the BLOOD-BRAIN BARRIER.
| Descriptor ID |
D062507
|
| MeSH Number(s) |
D12.776.543.940.200.500
|
| Concept/Terms |
Claudin-5- Claudin-5
- Transmembrane Protein Deleted in Velocardiofacial Syndrome
- TMVCF Protein
- Claudin 5
|
Below are MeSH descriptors whose meaning is more general than "Claudin-5".
Below are MeSH descriptors whose meaning is more specific than "Claudin-5".
This graph shows the total number of publications written about "Claudin-5" by people in this website by year, and whether "Claudin-5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Claudin-5" by people in Profiles.
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Mlc1-Expressing Perivascular Astrocytes Promote Blood-Brain Barrier Integrity. J Neurosci. 2022 02 23; 42(8):1406-1416.
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TGF?1 exacerbates blood-brain barrier permeability in a mouse model of hepatic encephalopathy via upregulation of MMP9 and downregulation of claudin-5. Lab Invest. 2015 Aug; 95(8):903-13.
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Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Biol Psychiatry. 2015 Apr 15; 77(8):749-63.
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GDNF restores human blood-nerve barrier function via RET tyrosine kinase-mediated cytoskeletal reorganization. Microvasc Res. 2012 May; 83(3):298-310.
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Claudin 5 expression in mouse seminiferous epithelium is dependent upon the transcription factor ets variant 5 and contributes to blood-testis barrier function. Biol Reprod. 2009 Nov; 81(5):871-9.