"Claudins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large family of transmembrane proteins found in TIGHT JUNCTIONS. They take part in the formation of paracellular barriers and pores that regulate paracellular permeability.
| Descriptor ID |
D057167
|
| MeSH Number(s) |
D12.776.543.940.200
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Claudins".
Below are MeSH descriptors whose meaning is more specific than "Claudins".
This graph shows the total number of publications written about "Claudins" by people in this website by year, and whether "Claudins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 1 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 1 | 2 |
| 2018 | 1 | 1 | 2 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Claudins" by people in Profiles.
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Argininosuccinate lyase deficiency causes blood-brain barrier disruption via nitric oxide-mediated dysregulation of claudin expression. JCI Insight. 2023 09 08; 8(17).
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Matrix metalloproteinase 7 contributes to intestinal barrier dysfunction by degrading tight junction protein Claudin-7. Front Immunol. 2022; 13:1020902.
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Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer. Cancer Res. 2022 06 15; 82(12):2281-2297.
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DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer. Proc Natl Acad Sci U S A. 2018 12 18; 115(51):E11978-E11987.
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Dietary Supplementation with Oleum Cinnamomi Improves Intestinal Functions in Piglets. Int J Mol Sci. 2018 Apr 25; 19(5).
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Cigarette smoke and decreased oxygen tension inhibit pulmonary claudin-6 expression. Exp Lung Res. 2016 Oct - Dec; 42(8-10):440-452.
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A common variant in the CLDN7/ELP5 locus predicts adiponectin change with lifestyle intervention and improved fitness in obese individuals with diabetes. Physiol Genomics. 2015 Jun; 47(6):215-24.
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Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential. Oncogene. 2015 Dec 03; 34(49):5997-6006.
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Conditional pulmonary over-expression of Claudin 6 during embryogenesis delays lung morphogenesis. Int J Dev Biol. 2015; 59(10-12):479-85.
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STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer. Stem Cells. 2014 Oct; 32(10):2571-82.