"Occludin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A MARVEL domain protein that binds to and regulates PROTEIN PHOSPHATASE 1. Occludin plays an important role in the formation and regulation of the TIGHT JUNCTION paracellular permeability barrier.
Descriptor ID |
D062793
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MeSH Number(s) |
D12.776.543.488.500 D12.776.543.940.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Occludin".
Below are MeSH descriptors whose meaning is more specific than "Occludin".
This graph shows the total number of publications written about "Occludin" by people in this website by year, and whether "Occludin" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2007 | 0 | 3 | 3 |
2008 | 0 | 2 | 2 |
2009 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2012 | 0 | 3 | 3 |
2014 | 1 | 1 | 2 |
2021 | 0 | 1 | 1 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Occludin" by people in Profiles.
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The Role of High Mobility Group Box B-1 in the Prognosis of Colorectal Cancer Based on the Changes in the Intestinal Mucosal Barrier. Technol Cancer Res Treat. 2024 Jan-Dec; 23:15330338231198972.
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MMP-12 knockdown prevents secondary brain damage after ischemic stroke in mice. Neurochem Int. 2022 12; 161:105432.
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Cathepsin S is a novel target for age-related dry eye. Exp Eye Res. 2022 01; 214:108895.
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Epithelial-Mesenchymal Transition (EMT) and Prostate Cancer. Adv Exp Med Biol. 2018; 1095:101-110.
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The effect of kiwifruit (Actinidia deliciosa) cysteine protease actinidin on the occludin tight junction network in T84 intestinal epithelial cells. Food Chem Toxicol. 2014 Oct; 72:61-8.
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Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms. Dig Liver Dis. 2014 Jun; 46(6):527-34.
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Global evaluation of Eph receptors and ephrins in lung adenocarcinomas identifies EphA4 as an inhibitor of cell migration and invasion. Mol Cancer Ther. 2012 Sep; 11(9):2021-32.
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CDH1 is essential for endometrial differentiation, gland development, and adult function in the mouse uterus. Biol Reprod. 2012 May; 86(5):141, 1-10.
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Potential contribution of hypoxia-inducible factor-1a, aquaporin-4, and matrix metalloproteinase-9 to blood-brain barrier disruption and brain edema after experimental subarachnoid hemorrhage. J Mol Neurosci. 2012 Sep; 48(1):273-80.
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Low humidity environmental challenge causes barrier disruption and cornification of the mouse corneal epithelium via a c-jun N-terminal kinase 2 (JNK2) pathway. Exp Eye Res. 2012 Jan; 94(1):150-6.