"Anoctamins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding.
| Descriptor ID |
D000075368
|
| MeSH Number(s) |
D12.776.157.530.400.175.032 D12.776.543.550.450.175.032 D12.776.543.585.400.175.032
|
| Concept/Terms |
Anoctamins- Anoctamins
- Anoctamin
- TMEM16 Protein Family
- Protein Family, TMEM16
- TMEM16 Proteins
|
Below are MeSH descriptors whose meaning is more general than "Anoctamins".
Below are MeSH descriptors whose meaning is more specific than "Anoctamins".
This graph shows the total number of publications written about "Anoctamins" by people in this website by year, and whether "Anoctamins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Anoctamins" by people in Profiles.
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Anoctamin 4 channel currents activate glucose-inhibited neurons in the mouse ventromedial hypothalamus during hypoglycemia. J Clin Invest. 2023 07 17; 133(14).
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Identification of Functional Genetic Determinants of Cardiac Troponin T and I in a Multiethnic Population and Causal Associations With Atrial Fibrillation. Circ Genom Precis Med. 2021 12; 14(6):e003460.
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Intramuscular interstitial amyloid deposition does not impact anoctaminopathy-5 phenotype. Muscle Nerve. 2019 01; 59(1):133-137.
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Gnathodiaphyseal dysplasia: Severe atypical presentation with novel heterozygous mutation of the anoctamin gene (ANO5). Bone. 2018 02; 107:161-171.