"Receptors, GABA-A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and contain an integral membrane chloride channel. Each receptor is assembled as a pentamer from a pool of at least 19 different possible subunits. The receptors belong to a superfamily that share a common CYSTEINE loop.
| Descriptor ID |
D011963
|
| MeSH Number(s) |
D12.776.157.530.400.175.562 D12.776.157.530.400.400.100.100 D12.776.543.550.450.175.562 D12.776.543.550.450.500.100.100 D12.776.543.585.400.175.562 D12.776.543.585.400.500.100.100 D12.776.543.750.130.500 D12.776.543.750.720.200.300.300
|
| Concept/Terms |
Receptors, GABA-A- Receptors, GABA-A
- Receptors, GABA A
- GABA-A Receptor
- GABA A Receptor
- Receptor, GABA-A
- GABA-A Receptors
- GABA A Receptors
- gamma-Aminobutyric Acid Subtype A Receptors
- gamma Aminobutyric Acid Subtype A Receptors
- Muscimol Receptor
- Receptor, Muscimol
- Receptors, Benzodiazepine-GABA
- Receptors, Benzodiazepine GABA
- Receptors, Muscimol
- Benzodiazepine-GABA Receptor
- Benzodiazepine GABA Receptor
- Receptor, Benzodiazepine-GABA
- GABA-Benzodiazepine Receptor
- GABA Benzodiazepine Receptor
- Receptor, GABA-Benzodiazepine
- GABA-Benzodiazepine Receptors
- GABA Benzodiazepine Receptors
- Benzodiazepine-Gaba Receptors
- Benzodiazepine Gaba Receptors
- Receptors, GABA-Benzodiazepine
- Receptors, GABA Benzodiazepine
- GABA(A) Receptor
- Muscimol Receptors
GABA-A Receptor delta Subunit- GABA-A Receptor delta Subunit
- GABA A Receptor delta Subunit
- delta Subunit, GABA-A Receptor
- delta Subunit, GABA A Receptor
GABA-A Receptor epsilon Subunit- GABA-A Receptor epsilon Subunit
- GABA A Receptor epsilon Subunit
- epsilon Subunit, GABA-A Receptor
- epsilon Subunit, GABA A Receptor
Benzodiazepine Receptor- Benzodiazepine Receptor
- Receptor, Benzodiazepine
- Receptors, Diazepam
- Diazepam Receptor
- Receptor, Diazepam
- Diazepam Receptors
- Benzodiazepine Receptors
- Receptors, Benzodiazepine
|
Below are MeSH descriptors whose meaning is more general than "Receptors, GABA-A".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Chloride Channels [D12.776.157.530.400.175]
- Receptors, GABA-A [D12.776.157.530.400.175.562]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
- Receptors, GABA-A [D12.776.157.530.400.400.100.100]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Chloride Channels [D12.776.543.550.450.175]
- Receptors, GABA-A [D12.776.543.550.450.175.562]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.450.500.100]
- Receptors, GABA-A [D12.776.543.550.450.500.100.100]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Chloride Channels [D12.776.543.585.400.175]
- Receptors, GABA-A [D12.776.543.585.400.175.562]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
- Receptors, GABA-A [D12.776.543.585.400.500.100.100]
- Receptors, Cell Surface [D12.776.543.750]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.130]
- Receptors, GABA-A [D12.776.543.750.130.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Amino Acid [D12.776.543.750.720.200]
- Receptors, GABA [D12.776.543.750.720.200.300]
- Receptors, GABA-A [D12.776.543.750.720.200.300.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, GABA-A".
This graph shows the total number of publications written about "Receptors, GABA-A" by people in this website by year, and whether "Receptors, GABA-A" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 3 | 3 |
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 3 | 3 |
| 2001 | 2 | 0 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 4 | 1 | 5 |
| 2007 | 1 | 1 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 2 | 3 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 2 | 0 | 2 |
| 2014 | 3 | 1 | 4 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 3 | 5 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 3 | 3 |
| 2023 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, GABA-A" by people in Profiles.
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Identification of a GABAergic neural circuit governing leptin signaling deficiency-induced obesity. Elife. 2023 04 12; 12.
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Spectrin-beta 2 facilitates the selective accumulation of GABAA receptors at somatodendritic synapses. Commun Biol. 2023 01 05; 6(1):11.
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Gabra5 plays a sexually dimorphic role in POMC neuron activity and glucose balance. Front Endocrinol (Lausanne). 2022; 13:889122.
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Gain-of-function variants in GABRD reveal a novel pathway for neurodevelopmental disorders and epilepsy. Brain. 2022 05 24; 145(4):1299-1309.
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Association of ultra-rare coding variants with genetic generalized epilepsy: A case-control whole exome sequencing study. Epilepsia. 2022 03; 63(3):723-735.
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Memory suppressor genes: Modulating acquisition, consolidation, and forgetting. Neuron. 2021 10 20; 109(20):3211-3227.
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Paraventricular hypothalamus mediates diurnal rhythm of metabolism. Nat Commun. 2020 07 30; 11(1):3794.
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Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection. Nat Neurosci. 2019 02; 22(2):205-217.
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A de novo GABRA2 missense mutation in severe early-onset epileptic encephalopathy with a choreiform movement disorder. Eur J Paediatr Neurol. 2018 May; 22(3):516-524.
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Deleterious Rare Variants Reveal Risk for Loss of GABAA Receptor Function in Patients with Genetic Epilepsy and in the General Population. PLoS One. 2016; 11(9):e0162883.