"Receptors, GABA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.
| Descriptor ID |
D018079
|
| MeSH Number(s) |
D12.776.543.750.720.200.300
|
| Concept/Terms |
Receptors, GABA- Receptors, GABA
- Receptors, gamma-Aminobutyric Acid
- Receptors, gamma Aminobutyric Acid
- gamma-Aminobutyric Acid Receptor
- Receptor, gamma-Aminobutyric Acid
- gamma Aminobutyric Acid Receptor
- gamma-Aminobutyric Acid Receptors
- gamma Aminobutyric Acid Receptors
- GABA Receptor
- Receptor, GABA
- GABA Receptors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, GABA".
Below are MeSH descriptors whose meaning is more specific than "Receptors, GABA".
This graph shows the total number of publications written about "Receptors, GABA" by people in this website by year, and whether "Receptors, GABA" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 0 | 3 | 3 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, GABA" by people in Profiles.
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Novel TSPO Ligand 2-Cl-MGV-1 Can Counteract Lipopolysaccharide Induced Inflammatory Response in Murine RAW264.7 Macrophage Cell Line and Lung Models. Cells. 2024 10 15; 13(20).
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Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping. Cerebellum. 2024 Feb; 23(1):31-51.
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The Effect of the Classical TSPO Ligand PK 11195 on In Vitro Cobalt Chloride Model of Hypoxia-like Condition in Lung and Brain Cell Lines. Biomolecules. 2022 Sep 29; 12(10).
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Translocator Protein 18 kDa PET Imaging Highlights Asymptomatic Isolated Cerebellar Dysplasia. Neurology. 2022 03 29; 98(13):538-539.
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Inhibitory Effects of the Two Novel TSPO Ligands 2-Cl-MGV-1 and MGV-1 on LPS-induced Microglial Activation. Cells. 2019 05 22; 8(5).
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Functional TSPO polymorphism predicts variance in the diurnal cortisol rhythm in bipolar disorder. Psychoneuroendocrinology. 2018 03; 89:194-202.
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In?vivo electroretinographic studies of the role of GABAC receptors in retinal signal processing. Exp Eye Res. 2015 Oct; 139:48-63.
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TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control. Autophagy. 2014; 10(12):2279-96.
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Rod vision is controlled by dopamine-dependent sensitization of rod bipolar cells by GABA. Neuron. 2011 Oct 06; 72(1):101-10.
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GABAC receptor binding of quantum-dot conjugates of variable ligand valency. Bioconjug Chem. 2010 Aug 18; 21(8):1455-64.