"Anoctamin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An anoctamin chloride channel expressed at high levels in the liver, skeletal muscle, and gastrointestinal muscles that functions in transepithelial anion transport and smooth muscle contraction. It is essential for the function of the INTERSTITIAL CELLS OF CAJAL and plays a major role in chloride conduction by airway epithelial cells and in tracheal cartilage development.
| Descriptor ID |
D000075369
|
| MeSH Number(s) |
D12.776.157.530.400.175.032.500 D12.776.543.550.450.175.032.500 D12.776.543.585.400.175.032.500
|
| Concept/Terms |
Anoctamin-1- Anoctamin-1
- Anoctamin 1
- Transmembrane Protein 16A
- TMEM16A Protein
|
Below are MeSH descriptors whose meaning is more general than "Anoctamin-1".
Below are MeSH descriptors whose meaning is more specific than "Anoctamin-1".
This graph shows the total number of publications written about "Anoctamin-1" by people in this website by year, and whether "Anoctamin-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Anoctamin-1" by people in Profiles.
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p90RSK pathway inhibition synergizes with cisplatin in TMEM16A overexpressing head and neck cancer. BMC Cancer. 2024 Feb 19; 24(1):233.
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Lysosomal inhibition sensitizes TMEM16A-expressing cancer cells to chemotherapy. Proc Natl Acad Sci U S A. 2022 03 22; 119(12):e2100670119.
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Acinic Cell Carcinoma of the Breast: Report of a Case With Immunohistochemical and Next-Generation Sequencing Studies. Int J Surg Pathol. 2021 Dec; 29(8):882-886.