"NADPH Oxidase 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An NADPH oxidase that is strongly expressed in the kidney. It forms a complex with CYBA-P22PHOX and produces intracellular SUPEROXIDES that may regulate cellular signaling in APOPTOSIS; BONE RESORPTION; and NF-KAPPA B activation.
| Descriptor ID |
D000074663
|
| MeSH Number(s) |
D08.811.682.608.575.937 D12.776.331.894.937 D12.776.543.653.937
|
| Concept/Terms |
NADPH Oxidase 4- NADPH Oxidase 4
- Oxidase 4, NADPH
- Renal NAD(P)H Oxidase
- Nox4 Protein
- Renox NAD(P)H Oxidase
|
Below are MeSH descriptors whose meaning is more general than "NADPH Oxidase 4".
Below are MeSH descriptors whose meaning is more specific than "NADPH Oxidase 4".
This graph shows the total number of publications written about "NADPH Oxidase 4" by people in this website by year, and whether "NADPH Oxidase 4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "NADPH Oxidase 4" by people in Profiles.
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NOX4-TIM23 interaction regulates NOX4 mitochondrial import and metabolic reprogramming. J Biol Chem. 2023 05; 299(5):104695.
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SIRT1-NOX4 signaling axis regulates cancer cachexia. J Exp Med. 2020 07 06; 217(7).
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Nox4 - RyR1 - Nox2: Regulators of micro-domain signaling in skeletal muscle. Redox Biol. 2020 09; 36:101557.
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Cardioprotective effects of a-cardiac actin on oxidative stress in a dilated cardiomyopathy mouse model. FASEB J. 2020 02; 34(2):2987-3005.
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Age-related distribution and potential role of SNCB in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. Exp Eye Res. 2019 08; 185:107676.
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Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma. Nat Commun. 2017 02 24; 8:14437.
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Rare and low-frequency coding variants alter human adult height. Nature. 2017 02 09; 542(7640):186-190.
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Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis. J Am Heart Assoc. 2016 09 28; 5(10).
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Oxidative stress promotes benign prostatic hyperplasia. Prostate. 2016 Jan; 76(1):58-67.
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8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1. Free Radic Biol Med. 2013 Aug; 61:384-94.