"NADPH Oxidase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An NADPH oxidase that functions as a voltage-gated proton channel expressed by PHAGOCYTES, especially in the colon. It regulates intracellular pH, generates SUPEROXIDES upon activation by PHAGOCYTOSIS, and may play a role in INNATE IMMUNITY.
| Descriptor ID |
D000074624
|
| MeSH Number(s) |
D08.811.682.608.575.750 D12.776.331.894.750 D12.776.543.653.750
|
| Concept/Terms |
NADPH Oxidase 1- NADPH Oxidase 1
- Oxidase 1, NADPH
- Mitogenic Oxidase 1
- Oxidase 1, Mitogenic
- NOX1 Protein
|
Below are MeSH descriptors whose meaning is more general than "NADPH Oxidase 1".
Below are MeSH descriptors whose meaning is more specific than "NADPH Oxidase 1".
This graph shows the total number of publications written about "NADPH Oxidase 1" by people in this website by year, and whether "NADPH Oxidase 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 2 | 2 |
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Below are the most recent publications written about "NADPH Oxidase 1" by people in Profiles.
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LRRC8A channels support TNFa-induced superoxide production by Nox1 which is required for receptor endocytosis. Free Radic Biol Med. 2016 12; 101:413-423.
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Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo. Free Radic Biol Med. 2012 Jul 15; 53(2):289-96.
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Novel role of NOX in supporting aerobic glycolysis in cancer cells with mitochondrial dysfunction and as a potential target for cancer therapy. PLoS Biol. 2012; 10(5):e1001326.