Monocarboxylic Acid Transporters
"Monocarboxylic Acid Transporters" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proteins involved in the transport of monocarboxylic acids such as LACTIC ACID and PYRUVIC ACID across cellular membranes.
| Descriptor ID |
D027501
|
| MeSH Number(s) |
D12.776.157.530.450.074.500.400 D12.776.543.585.450.074.500.300
|
| Concept/Terms |
Monocarboxylic Acid Transporters- Monocarboxylic Acid Transporters
- Acid Transporters, Monocarboxylic
- Transporters, Monocarboxylic Acid
- Monocarboxylate Translocator
- Translocator, Monocarboxylate
- Monocarboxylic Acid Transport Proteins
- MCT Proteins
- Monocarboxylic Acid Transport Protein
Erythrocyte Lactate Transporters- Erythrocyte Lactate Transporters
- Lactate Transporters, Erythrocyte
- Transporters, Erythrocyte Lactate
- Erythrocyte Lactate Transporter
- Lactate Transporter, Erythrocyte
- Transporter, Erythrocyte Lactate
Lactate Transport Proteins- Lactate Transport Proteins
- Transport Proteins, Lactate
- Lactate Transport Protein
- Transport Protein, Lactate
- Lactate Transporter
- Transporter, Lactate
- Lactate Translocase
- Translocase, Lactate
|
Below are MeSH descriptors whose meaning is more general than "Monocarboxylic Acid Transporters".
Below are MeSH descriptors whose meaning is more specific than "Monocarboxylic Acid Transporters".
This graph shows the total number of publications written about "Monocarboxylic Acid Transporters" by people in this website by year, and whether "Monocarboxylic Acid Transporters" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 2 | 0 | 2 |
| 2020 | 3 | 1 | 4 |
| 2021 | 2 | 0 | 2 |
| 2022 | 1 | 2 | 3 |
| 2023 | 1 | 1 | 2 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Monocarboxylic Acid Transporters" by people in Profiles.
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Severely polarized extracellular acidity around tumour cells. Nat Biomed Eng. 2024 Jun; 8(6):787-799.
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Prostate lineage-specific metabolism governs luminal differentiation and response to antiandrogen treatment. Nat Cell Biol. 2023 Dec; 25(12):1821-1832.
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Metabolism-based targeting of MYC via MPC-SOD2 axis-mediated oxidation promotes cellular differentiation in group 3 medulloblastoma. Nat Commun. 2023 05 02; 14(1):2502.
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Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes. Sci Adv. 2022 11 18; 8(46):eadd5430.
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Gut-derived butyrate suppresses ocular surface inflammation. Sci Rep. 2022 03 16; 12(1):4512.
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Long-Term Efficacy of T3 Analogue Triac in Children and Adults With MCT8 Deficiency: A Real-Life Retrospective Cohort Study. J Clin Endocrinol Metab. 2022 02 17; 107(3):e1136-e1147.
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Excess exogenous pyruvate inhibits lactate dehydrogenase activity in live cells in an MCT1-dependent manner. J Biol Chem. 2021 07; 297(1):100775.
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Clinical and Functional Consequences of C-Terminal Variants in MCT8: A Case Series. J Clin Endocrinol Metab. 2021 01 23; 106(2):539-553.
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The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure. Cell Metab. 2021 03 02; 33(3):629-648.e10.
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Hyperpolarized [1-13C]pyruvate-to-[1-13C]lactate conversion is rate-limited by monocarboxylate transporter-1 in the plasma membrane. Proc Natl Acad Sci U S A. 2020 09 08; 117(36):22378-22389.