"NADPH Oxidase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE.
| Descriptor ID |
D000074662
|
| MeSH Number(s) |
D08.811.682.608.575.875 D12.776.331.894.875 D12.776.543.653.875
|
| Concept/Terms |
NADPH Oxidase 2- NADPH Oxidase 2
- Oxidase 2, NADPH
- Chronic Granulomatous Disease Protein
- GP91-PHOX Protein
- GP91 PHOX Protein
- CYBB Protein
- Cytochrome B-245 Beta Chain
- Cytochrome B 245 Beta Chain
- NOX2 Protein
|
Below are MeSH descriptors whose meaning is more general than "NADPH Oxidase 2".
Below are MeSH descriptors whose meaning is more specific than "NADPH Oxidase 2".
This graph shows the total number of publications written about "NADPH Oxidase 2" by people in this website by year, and whether "NADPH Oxidase 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 4 | 4 |
| 2011 | 0 | 3 | 3 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 4 | 4 |
| 2014 | 0 | 2 | 2 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2020 | 0 | 3 | 3 |
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Below are the most recent publications written about "NADPH Oxidase 2" by people in Profiles.
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Interaction of Signaling Lymphocytic Activation Molecule Family 1 (SLAMF1) receptor with Trypanosoma cruzi is strain-dependent and affects NADPH oxidase expression and activity. PLoS Negl Trop Dis. 2020 09; 14(9):e0008608.
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Nox4 - RyR1 - Nox2: Regulators of micro-domain signaling in skeletal muscle. Redox Biol. 2020 09; 36:101557.
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Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy. J Clin Invest. 2020 04 01; 130(4):1713-1727.
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Cardioprotective effects of a-cardiac actin on oxidative stress in a dilated cardiomyopathy mouse model. FASEB J. 2020 02; 34(2):2987-3005.
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Mechanisms underlying modulation of podocyte TRPC6 channels by suPAR: Role of NADPH oxidases and Src family tyrosine kinases. Biochim Biophys Acta Mol Basis Dis. 2018 10; 1864(10):3527-3536.
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Oxidized CaMKII (Ca2+/Calmodulin-Dependent Protein Kinase II) Is Essential for Ventricular Arrhythmia in a Mouse Model of Duchenne Muscular Dystrophy. Circ Arrhythm Electrophysiol. 2018 04; 11(4):e005682.
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NADPH oxidase mediates microtubule alterations and diaphragm dysfunction in dystrophic mice. Elife. 2018 01 30; 7.
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Opposing Actions of Fibroblast and Cardiomyocyte Smad3 Signaling in the Infarcted Myocardium. Circulation. 2018 02 13; 137(7):707-724.
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Multiple Brain Abscesses Caused by Trichosporon inkin in a Patient with X-Linked Chronic Granulomatous Disease (CGD) Successfully Treated with Antifungal Therapy. J Clin Immunol. 2017 08; 37(6):519-523.
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Mito-Apocynin Prevents Mitochondrial Dysfunction, Microglial Activation, Oxidative Damage, and Progressive Neurodegeneration in MitoPark Transgenic Mice. Antioxid Redox Signal. 2017 Nov 10; 27(14):1048-1066.