"APOBEC-1 Deaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An APOBEC deaminase catalytic subunit of the apolipoprotein B (APOB) MESSENGER RNA (mRNA) editing enzyme complex that is involved in post-transcriptional editing of a CAA codon for GLYCINE to a UAA STOP CODON in the ApoB mRNA. It also functions in CGA (ARGININE) to UGA STOP CODON editing of NEUROFIBROMIN 1 mRNA and EPIGENETIC PROCESSES.
| Descriptor ID |
D000071479
|
| MeSH Number(s) |
D08.811.277.151.486.250.500.500
|
| Concept/Terms |
APOBEC-1 Deaminase- APOBEC-1 Deaminase
- APOBEC 1 Deaminase
- Deaminase, APOBEC-1
- ApoB mRNA Editing Catalytic Subunit
- Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide 1
- APOBEC-1
- APOBEC1 Deaminase
- Deaminase, APOBEC1
- APOBEC1 Protein
- APOBEC-1 Protein
- APOBEC 1 Protein
- HEPR Protein
|
Below are MeSH descriptors whose meaning is more general than "APOBEC-1 Deaminase".
Below are MeSH descriptors whose meaning is more specific than "APOBEC-1 Deaminase".
This graph shows the total number of publications written about "APOBEC-1 Deaminase" by people in this website by year, and whether "APOBEC-1 Deaminase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 3 | 3 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "APOBEC-1 Deaminase" by people in Profiles.
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Spatio-temporal dynamics of intra-host variability in SARS-CoV-2 genomes. Nucleic Acids Res. 2022 02 22; 50(3):1551-1561.
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Epac1 (Exchange Protein Directly Activated by cAMP 1) Upregulates LOX-1 (Oxidized Low-Density Lipoprotein Receptor 1) to Promote Foam Cell Formation and Atherosclerosis Development. Arterioscler Thromb Vasc Biol. 2020 12; 40(12):e322-e335.
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Apobec1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver. RNA. 2019 01; 25(1):70-81.
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Correction of ?-thalassemia mutant by base editor in human embryos. Protein Cell. 2017 Nov; 8(11):811-822.
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Effective gene editing by high-fidelity base editor 2 in mouse zygotes. Protein Cell. 2017 Aug; 8(8):601-611.
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Integrated genomic and molecular characterization of cervical cancer. Nature. 2017 03 16; 543(7645):378-384.
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Fortilin reduces apoptosis in macrophages and promotes atherosclerosis. Am J Physiol Heart Circ Physiol. 2013 Nov 15; 305(10):H1519-29.
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Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia. Hum Gene Ther. 2013 Jan; 24(1):19-26.
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Transgenerational epigenetic effects of the Apobec1 cytidine deaminase deficiency on testicular germ cell tumor susceptibility and embryonic viability. Proc Natl Acad Sci U S A. 2012 Oct 09; 109(41):E2766-73.
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Mutational processes molding the genomes of 21 breast cancers. Cell. 2012 May 25; 149(5):979-93.