"APOBEC-3G Deaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An APOBEC deaminase that functions as an inhibitor of RETROVIRIDAE replication and inhibits the mobility of RETROTRANSPOSONS via deaminase-dependent and independent mechanisms. It is selective for SINGLE-STRANDED DNA and does not deaminate double-stranded DNA or single or DOUBLE-STRANDED RNA. It exhibits potent antiviral activity against VIF PROTEIN deficient HIV-1 through the creation of hypermutations in the VIRAL DNA. It also has anti-viral activity against SIMIAN IMMUNODEFICIENCY VIRUSES and HEPATITIS B VIRUS.
| Descriptor ID |
D000071480
|
| MeSH Number(s) |
D08.811.277.151.486.250.500.750
|
| Concept/Terms |
APOBEC-3G Deaminase- APOBEC-3G Deaminase
- APOBEC 3G Deaminase
- Deaminase, APOBEC-3G
- APOBEC-Related Cytidine Deaminase
- APOBEC Related Cytidine Deaminase
- Cytidine Deaminase, APOBEC-Related
- APOBEC3G Protein
- CEM15 Protein
- APOBEC3G Deaminase
- Deaminase, APOBEC3G
- APOBEC-3G Protein
- APOBEC 3G Protein
- APOBEC-Related Protein
- APOBEC Related Protein
- APOBEC-3G dC-dU Editing Enzyme
- APOBEC 3G dC dU Editing Enzyme
|
Below are MeSH descriptors whose meaning is more general than "APOBEC-3G Deaminase".
Below are MeSH descriptors whose meaning is more specific than "APOBEC-3G Deaminase".
This graph shows the total number of publications written about "APOBEC-3G Deaminase" by people in this website by year, and whether "APOBEC-3G Deaminase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "APOBEC-3G Deaminase" by people in Profiles.
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Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes. Hum Genomics. 2019 08 20; 13(1):37.
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APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis. J Clin Invest. 2011 Nov; 121(11):4526-36.
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Mice deficient in APOBEC2 and APOBEC3. Mol Cell Biol. 2005 Aug; 25(16):7270-7.