"APOBEC Deaminases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of conserved cytidine deaminases that catalyze the DEAMINATION of CYTIDINE to URIDINE. They are characterized by N and C-terminal zinc-dependent catalytic domains and have important functions in RNA EDITING; EPIGENTIC PROCESSES; and the INNATE IMMUNE RESPONSE against viruses.
| Descriptor ID |
D000071478
|
| MeSH Number(s) |
D08.811.277.151.486.250.500
|
| Concept/Terms |
APOBEC Deaminases- APOBEC Deaminases
- Deaminases, APOBEC
- APOBEC Family Proteins
- APOBEC Enzymes
- Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptides
- AID-APOBEC Deaminases
- AID APOBEC Deaminases
- Deaminases, AID-APOBEC
|
Below are MeSH descriptors whose meaning is more general than "APOBEC Deaminases".
Below are MeSH descriptors whose meaning is more specific than "APOBEC Deaminases".
This graph shows the total number of publications written about "APOBEC Deaminases" by people in this website by year, and whether "APOBEC Deaminases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "APOBEC Deaminases" by people in Profiles.
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Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy. Cell. 2020 11 25; 183(5):1436-1456.e31.
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APOBEC mutation drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa. Sci Transl Med. 2018 08 22; 10(455).
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HIV-1 and HIV-2 exhibit similar mutation frequencies and spectra in the absence of G-to-A hypermutation. Retrovirology. 2015 Jul 10; 12:60.
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Mice deficient in APOBEC2 and APOBEC3. Mol Cell Biol. 2005 Aug; 25(16):7270-7.