"Glycerol Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the formation of glycerol 3-phosphate from ATP and glycerol. Dihydroxyacetone and L-glyceraldehyde can also act as acceptors; UTP and, in the case of the yeast enzyme, ITP and GTP can act as donors. It provides a way for glycerol derived from fats or glycerides to enter the glycolytic pathway. EC 2.7.1.30.
| Descriptor ID |
D005991
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| MeSH Number(s) |
D08.811.913.696.620.275
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glycerol Kinase".
Below are MeSH descriptors whose meaning is more specific than "Glycerol Kinase".
This graph shows the total number of publications written about "Glycerol Kinase" by people in this website by year, and whether "Glycerol Kinase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1996 | 2 | 0 | 2 |
| 1997 | 1 | 0 | 1 |
| 1999 | 1 | 1 | 2 |
| 2000 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glycerol Kinase" by people in Profiles.
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Inborn errors of cytoplasmic triglyceride metabolism. J Inherit Metab Dis. 2015 Jan; 38(1):85-98.
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Disruption of glycerol metabolism by RNAi targeting of genes encoding glycerol kinase results in a range of phenotype severity in Drosophila. PLoS One. 2013; 8(9):e71664.
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Glycerol hypersensitivity in a Drosophila model for glycerol kinase deficiency is affected by mutations in eye pigmentation genes. PLoS One. 2012; 7(3):e31779.
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Aquaporin 7 is a beta-cell protein and regulator of intraislet glycerol content and glycerol kinase activity, beta-cell mass, and insulin production and secretion. Mol Cell Biol. 2007 Sep; 27(17):6026-37.
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Tissue-dependent alterations in lipid mass in mice lacking glycerol kinase. Lipids. 2005 Mar; 40(3):287-93.
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AluY insertion (IVS4-52ins316alu) in the glycerol kinase gene from an individual with benign glycerol kinase deficiency. Hum Mutat. 2000; 15(4):316-23.
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Retrotransposition of glycerol kinase-related genes from the X chromosome to autosomes: functional and evolutionary aspects. Genomics. 1999 Aug 01; 59(3):282-90.
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Further associations of congenital heart disease and genetic syndromes: report of a case of tetralogy of Fallot and Fabry's disease. Pediatr Cardiol. 1999 May-Jun; 20(3):236-7.
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X-linked glycerol kinase deficiency in the mouse leads to growth retardation, altered fat metabolism, autonomous glucocorticoid secretion and neonatal death. Hum Mol Genet. 1997 Oct; 6(11):1803-9.
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Ahch, the mouse homologue of DAX1: cloning, characterization and synteny with GyK, the glycerol kinase locus. Gene. 1996 Oct 31; 178(1-2):31-4.