"Diacylglycerol Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the transferase class that uses ATP to catalyze the phosphorylation of diacylglycerol to a phosphatidate. EC 2.7.1.107.
| Descriptor ID |
D019852
|
| MeSH Number(s) |
D08.811.913.696.620.200
|
| Concept/Terms |
Diacylglycerol Kinase- Diacylglycerol Kinase
- Kinase, Diacylglycerol
- 1,2-Diacylglycerol Kinase
- 1,2 Diacylglycerol Kinase
- Kinase, 1,2-Diacylglycerol
- DAG Kinase
- Kinase, DAG
- Diglyceride Kinase
- Kinase, Diglyceride
|
Below are MeSH descriptors whose meaning is more general than "Diacylglycerol Kinase".
Below are MeSH descriptors whose meaning is more specific than "Diacylglycerol Kinase".
This graph shows the total number of publications written about "Diacylglycerol Kinase" by people in this website by year, and whether "Diacylglycerol Kinase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 2 | 0 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2005 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Diacylglycerol Kinase" by people in Profiles.
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DGK? Knock-Out Mice Show Impairments in Cerebellar Motor Coordination, LTD, and the Dendritic Development of Purkinje Cells through the Activation of PKC?. eNeuro. 2020 Mar/Apr; 7(2).
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The role of genetic variation in DGKK on moderate and severe hypospadias. Birth Defects Res. 2019 08 01; 111(13):932-937.
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Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha. Neuro Oncol. 2018 01 22; 20(2):192-202.
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Ritanserin, a novel agent targeting the mesenchymal subtype of glioblastomas. Neuro Oncol. 2018 01 22; 20(2):151-152.
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Diacylglycerol kinase synthesized by commensal Lactobacillus reuteri diminishes protein kinase C phosphorylation and histamine-mediated signaling in the mammalian intestinal epithelium. Mucosal Immunol. 2018 03; 11(2):380-393.
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Loss of diacylglycerol kinase epsilon in mice causes endothelial distress and impairs glomerular Cox-2 and PGE2 production. Am J Physiol Renal Physiol. 2016 05 01; 310(9):F895-908.
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DGKE disruption ditches complement and drives p38 signaling. Blood. 2015 Feb 05; 125(6):898-9.
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Candidate gene associations with mood disorder, cognitive vulnerability, and fronto-limbic volumes. Brain Behav. 2014 May; 4(3):418-30.
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Not expecting the unexpected: diacylglycerol kinase alpha as a cancer target. Cancer Discov. 2013 Jul; 3(7):726-7.
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DGKE variants cause a glomerular microangiopathy that mimics membranoproliferative GN. J Am Soc Nephrol. 2013 Feb; 24(3):377-84.