1-Phosphatidylinositol 4-Kinase
"1-Phosphatidylinositol 4-Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of phosphatidylinositol (PHOSPHATIDYLINOSITOLS) to phosphatidylinositol 4-phosphate, the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.
| Descriptor ID |
D019870
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| MeSH Number(s) |
D08.811.913.696.620.550
|
| Concept/Terms |
1-Phosphatidylinositol 4-Kinase- 1-Phosphatidylinositol 4-Kinase
- 1 Phosphatidylinositol 4 Kinase
- Phosphoinositide Kinase
- Kinase, Phosphoinositide
- Phosphatidylinositiol Kinase
- Kinase, Phosphatidylinositiol
- Phosphatidylinositol 4-Kinase
- Phosphatidylinositol 4 Kinase
- PI 4-Kinase
- PI 4 Kinase
- Phosphatidylinositol Kinase Type II
- PtdIns 4-Kinase
- PtdIns 4 Kinase
|
Below are MeSH descriptors whose meaning is more general than "1-Phosphatidylinositol 4-Kinase".
Below are MeSH descriptors whose meaning is more specific than "1-Phosphatidylinositol 4-Kinase".
This graph shows the total number of publications written about "1-Phosphatidylinositol 4-Kinase" by people in this website by year, and whether "1-Phosphatidylinositol 4-Kinase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 1 | 1 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "1-Phosphatidylinositol 4-Kinase" by people in Profiles.
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Two-pore channel blockade by phosphoinositide kinase inhibitors YM201636 and PI-103 determined by a histidine residue near pore-entrance. Commun Biol. 2022 07 23; 5(1):738.
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Translational control of lipogenesis links protein synthesis and phosphoinositide signaling with nuclear division in Saccharomyces cerevisiae. Genetics. 2022 Jan 04; 220(1).
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Addiction to Golgi-resident PI4P synthesis in chromosome 1q21.3-amplified lung adenocarcinoma cells. Proc Natl Acad Sci U S A. 2021 06 22; 118(25).
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Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish. Dis Model Mech. 2011 Sep; 4(5):607-21.
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A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability. Genes Dev. 2010 Sep 01; 24(17):1939-50.
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Isoform-selective phosphoinositide 3'-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach. Blood. 2009 May 28; 113(22):5549-57.
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Group B streptococcus exploits lipid rafts and phosphoinositide 3-kinase/Akt signaling pathway to invade human endometrial cells. Am J Obstet Gynecol. 2008 Nov; 199(5):548.e1-9.
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Inhibitors of phosphoinositide 3-kinase cause defects in the postendocytic sorting of beta2-adrenergic receptors. Exp Cell Res. 2007 Jul 15; 313(12):2586-96.
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A novel link between integrins, transmembrane-4 superfamily proteins (CD63 and CD81), and phosphatidylinositol 4-kinase. J Biol Chem. 1997 Jan 31; 272(5):2595-8.
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Signal transduction pathways involving the small G proteins rac and Cdc42 and phosphoinositide kinases. Adv Enzyme Regul. 1997; 37:377-90.