"Carboxypeptidase H" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ZINC-containing exopeptidase primarily found in SECRETORY VESICLES of endocrine and neuroendocrine cells. It catalyzes the cleavage of C-terminal ARGININE or LYSINE residues from polypeptides and is active in processing precursors of PEPTIDE HORMONES and other bioactive peptides.
| Descriptor ID |
D043423
|
| MeSH Number(s) |
D08.811.277.656.350.245.167 D08.811.277.656.350.555.250 D08.811.277.656.675.555.250 D08.811.277.656.837.124
|
| Concept/Terms |
Carboxypeptidase H- Carboxypeptidase H
- Enkephalin-Synthesizing Carboxypeptidase
- Carboxypeptidase, Enkephalin-Synthesizing
- Enkephalin Synthesizing Carboxypeptidase
- Enkephalin-Forming Carboxypeptidase
- Carboxypeptidase, Enkephalin-Forming
- Enkephalin Forming Carboxypeptidase
- Carboxypeptidase E
- Enkephalin Convertase
- Convertase, Enkephalin
|
Below are MeSH descriptors whose meaning is more general than "Carboxypeptidase H".
Below are MeSH descriptors whose meaning is more specific than "Carboxypeptidase H".
This graph shows the total number of publications written about "Carboxypeptidase H" by people in this website by year, and whether "Carboxypeptidase H" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Carboxypeptidase H" by people in Profiles.
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Central Sirt1 regulates body weight and energy expenditure along with the POMC-derived peptide a-MSH and the processing enzyme CPE production in diet-induced obese male rats. Endocrinology. 2015 Mar; 156(3):961-74.
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Effect of antigen sensitization and challenge on oscillatory mechanics of the lung and pulmonary inflammation in obese carboxypeptidase E-deficient mice. Am J Physiol Regul Integr Comp Physiol. 2014 Sep 15; 307(6):R621-33.
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Central Sirt1 regulates body weight and energy expenditure along with the POMC-derived peptide a-MSH and the processing enzyme CPE production in diet-induced obese male rats. Endocrinology. 2014 Jul; 155(7):2423-35.
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The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake. Nat Med. 2009 Oct; 15(10):1195-201.
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Proinsulin processing in the diabetic Goto-Kakizaki rat. J Endocrinol. 2002 Dec; 175(3):637-47.