"DNA Glycosylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of DNA repair enzymes that recognize damaged nucleotide bases and remove them by hydrolyzing the N-glycosidic bond that attaches them to the sugar backbone of the DNA molecule. The process called BASE EXCISION REPAIR can be completed by a DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE which excises the remaining RIBOSE sugar from the DNA.
| Descriptor ID |
D045647
|
| MeSH Number(s) |
D08.811.074.249 D08.811.277.450.430.099
|
| Concept/Terms |
DNA Glycosylases- DNA Glycosylases
- Glycosylases, DNA
- DNA Glycosylase
- Glycosylase, DNA
- DNA N-glycosidase
- DNA N glycosidase
|
Below are MeSH descriptors whose meaning is more general than "DNA Glycosylases".
Below are MeSH descriptors whose meaning is more specific than "DNA Glycosylases".
This graph shows the total number of publications written about "DNA Glycosylases" by people in this website by year, and whether "DNA Glycosylases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 2 | 0 | 2 |
| 1996 | 2 | 0 | 2 |
| 1998 | 2 | 1 | 3 |
| 1999 | 4 | 1 | 5 |
| 2000 | 2 | 1 | 3 |
| 2001 | 1 | 1 | 2 |
| 2003 | 2 | 0 | 2 |
| 2004 | 3 | 0 | 3 |
| 2005 | 0 | 3 | 3 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 2 | 3 |
| 2008 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 3 | 2 | 5 |
| 2013 | 2 | 0 | 2 |
| 2014 | 5 | 1 | 6 |
| 2015 | 5 | 1 | 6 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "DNA Glycosylases" by people in Profiles.
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The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infection. Nat Commun. 2023 Dec 09; 14(1):8169.
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Intrapulmonary administration of purified NEIL2 abrogates NF-?B-mediated inflammation. J Biol Chem. 2021 Jan-Jun; 296:100723.
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Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin. Nucleic Acids Res. 2021 01 11; 49(1):221-243.
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Duodenal Adenomas and Cancer in MUTYH-associated Polyposis: An International Cohort Study. Gastroenterology. 2021 02; 160(3):952-954.e4.
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Comprehensive Profiling of DNA Repair Defects in Breast Cancer Identifies a Novel Class of Endocrine Therapy Resistance Drivers. Clin Cancer Res. 2018 10 01; 24(19):4887-4899.
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Pollen-induced oxidative DNA damage response regulates miRNAs controlling allergic inflammation. Am J Physiol Lung Cell Mol Physiol. 2017 Dec 01; 313(6):L1058-L1068.
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Whole-genome landscape of pancreatic neuroendocrine tumours. Nature. 2017 03 02; 543(7643):65-71.
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Endoplasmic reticulum stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG, and Rad51. Neuro Oncol. 2016 08; 18(8):1109-19.
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Molecular biology: DNA repair without flipping out. Nature. 2015 Nov 12; 527(7577):168-9.
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Differential timing of oxidative DNA damage and telomere shortening in hepatitis C and B virus-related liver carcinogenesis. Transl Res. 2016 Feb; 168:122-133.