"DNA Glycosylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of DNA repair enzymes that recognize damaged nucleotide bases and remove them by hydrolyzing the N-glycosidic bond that attaches them to the sugar backbone of the DNA molecule. The process called BASE EXCISION REPAIR can be completed by a DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE which excises the remaining RIBOSE sugar from the DNA.
| Descriptor ID |
D045647
|
| MeSH Number(s) |
D08.811.074.249 D08.811.277.450.430.099
|
| Concept/Terms |
DNA Glycosylases- DNA Glycosylases
- Glycosylases, DNA
- DNA Glycosylase
- Glycosylase, DNA
- DNA N-glycosidase
- DNA N glycosidase
|
Below are MeSH descriptors whose meaning is more general than "DNA Glycosylases".
Below are MeSH descriptors whose meaning is more specific than "DNA Glycosylases".
This graph shows the total number of publications written about "DNA Glycosylases" by people in this website by year, and whether "DNA Glycosylases" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 2 | 0 | 2 |
| 2014 | 3 | 0 | 3 |
| 2015 | 4 | 0 | 4 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 2 | 2 |
| 2018 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Glycosylases" by people in Profiles.
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Th17 cells require the DNA repair sensor xeroderma pigmentosum complementation Group C to control oxidative DNA damage in a murine model. Nat Commun. 2026 Apr 01; 17(1).
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The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infection. Nat Commun. 2023 12 09; 14(1):8169.
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Summary of the experiences, knowledge, medical management, and family communication of monoallelic MUTYH carriers. J Genet Couns. 2023 04; 32(2):342-350.
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Intrapulmonary administration of purified NEIL2 abrogates NF-?B-mediated inflammation. J Biol Chem. 2021 Jan-Jun; 296:100723.
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Comprehensive Profiling of DNA Repair Defects in Breast Cancer Identifies a Novel Class of Endocrine Therapy Resistance Drivers. Clin Cancer Res. 2018 10 01; 24(19):4887-4899.
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Pollen-induced oxidative DNA damage response regulates miRNAs controlling allergic inflammation. Am J Physiol Lung Cell Mol Physiol. 2017 Dec 01; 313(6):L1058-L1068.
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Whole-genome landscape of pancreatic neuroendocrine tumours. Nature. 2017 03 02; 543(7643):65-71.
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Enhanced sensitivity of Neil1-/- mice to chronic UVB exposure. DNA Repair (Amst). 2016 12; 48:43-50.
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Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation. J Biol Chem. 2015 Oct 09; 290(41):24636-48.
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Whole transcriptome analysis reveals a role for OGG1-initiated DNA repair signaling in airway remodeling. Free Radic Biol Med. 2015 Dec; 89:20-33.