"Leucyl Aminopeptidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A zinc containing enzyme of the hydrolase class that catalyzes the removal of the N-terminal amino acid from most L-peptides, particularly those with N-terminal leucine residues but not those with N-terminal lysine or arginine residues. This occurs in tissue cell cytosol, with high activity in the duodenum, liver, and kidney. The activity of this enzyme is commonly assayed using a leucine arylamide chromogenic substrate such as leucyl beta-naphthylamide.
| Descriptor ID |
D007931
|
| MeSH Number(s) |
D08.811.277.656.350.100.511 D08.811.277.656.350.555.700 D08.811.277.656.675.555.700
|
| Concept/Terms |
Leucyl Aminopeptidase- Leucyl Aminopeptidase
- Aminopeptidase, Leucyl
- L-Leucylnaphthylamidase
- Zinc-Manganese-Leucine Aminopeptidase
- Aminopeptidase, Zinc-Manganese-Leucine
- Zinc Manganese Leucine Aminopeptidase
- Peptidase S
- Cytosol Aminopeptidase
- Aminopeptidase, Cytosol
- Leucine Aminopeptidase
- Aminopeptidase, Leucine
|
Below are MeSH descriptors whose meaning is more general than "Leucyl Aminopeptidase".
Below are MeSH descriptors whose meaning is more specific than "Leucyl Aminopeptidase".
This graph shows the total number of publications written about "Leucyl Aminopeptidase" by people in this website by year, and whether "Leucyl Aminopeptidase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leucyl Aminopeptidase" by people in Profiles.
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Analysis of the role of bleomycin hydrolase in antigen presentation and the generation of CD8 T cell responses. J Immunol. 2007 Jun 01; 178(11):6923-30.
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Influence of Ramadan-type fasting on enzymes of carbohydrate metabolism and brush border membrane in small intestine and liver of rat used as a model. Br J Nutr. 2006 Dec; 96(6):1087-94.
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Characterization of a cytosolic aminopeptidase from Encephalitozoon intestinalis. Parasitology. 2002 Jan; 124(Pt 1):1-7.
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Prenatal diagnosis of cystic fibrosis: microvillar enzymes and DNA analysis compared. Clin Chem. 1988 May; 34(5):933-7.
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Bone marrow derived macrophages have polyamine and ectoenzyme phenotypes distinct from resident macrophages. Life Sci. 1988; 42(20):2019-27.
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A phase I evaluation of the quinazoline antifolate thymidylate synthase inhibitor, N10-propargyl-5,8-dideazafolic acid, CB3717. J Clin Oncol. 1986 Aug; 4(8):1245-52.