Electron Transport Complex IV
"Electron Transport Complex IV" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multisubunit enzyme complex containing CYTOCHROME A GROUP; CYTOCHROME A3; two copper atoms; and 13 different protein subunits. It is the terminal oxidase complex of the RESPIRATORY CHAIN and collects electrons that are transferred from the reduced CYTOCHROME C GROUP and donates them to molecular OXYGEN, which is then reduced to water. The redox reaction is simultaneously coupled to the transport of PROTONS across the inner mitochondrial membrane.
| Descriptor ID |
D003576
|
| MeSH Number(s) |
D05.500.562.374 D08.811.600.250.687 D08.811.682.285 D12.776.157.530.450.250.875.304 D12.776.543.277.687 D12.776.543.585.450.250.875.484
|
| Concept/Terms |
Electron Transport Complex IV- Electron Transport Complex IV
- Ferrocytochrome c Oxygen Oxidoreductase
- Cytochrome-c Oxidase (Complex IV)
- Cytochrome Oxidase
- Oxidase, Cytochrome
- Cytochrome-c Oxidase
- Cytochrome c Oxidase
- Oxidase, Cytochrome-c
Signal Peptide p25-Subunit IV Cytochrome Oxidase- Signal Peptide p25-Subunit IV Cytochrome Oxidase
- Signal Peptide p25 Subunit IV Cytochrome Oxidase
- Pre-CTOX p25
- p25 Presequence Peptide-Cytochrome Oxidase
- p25 Presequence Peptide Cytochrome Oxidase
Cytochrome aa3- Cytochrome aa3
- Heme aa3 Cytochrome Oxidase
- Cytochrome a,a3
|
Below are MeSH descriptors whose meaning is more general than "Electron Transport Complex IV".
Below are MeSH descriptors whose meaning is more specific than "Electron Transport Complex IV".
This graph shows the total number of publications written about "Electron Transport Complex IV" by people in this website by year, and whether "Electron Transport Complex IV" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 3 | 3 |
| 1999 | 1 | 1 | 2 |
| 2001 | 1 | 1 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 5 | 3 | 8 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 2 | 0 | 2 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 2 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 2 | 3 | 5 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Electron Transport Complex IV" by people in Profiles.
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A novel acceptor stem variant in mitochondrial tRNATyr impairs mitochondrial translation and is associated with a severe phenotype. Mol Genet Metab. 2020 12; 131(4):398-404.
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Biallelic variants in COX4I1 associated with a novel phenotype resembling Leigh syndrome with developmental regression, intellectual disability, and seizures. Am J Med Genet A. 2019 10; 179(10):2138-2143.
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OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect. EMBO Mol Med. 2018 11; 10(11).
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Pitx2 maintains mitochondrial function during regeneration to prevent myocardial fat deposition. Development. 2018 09 26; 145(18).
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First Molecular Identification and Phylogeny of Moroccan Anopheles sergentii (Diptera: Culicidae) Based on Second Internal Transcribed Spencer (ITS2) and Cytochrome c Oxidase I (COI) Sequences. Vector Borne Zoonotic Dis. 2018 09; 18(9):479-484.
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Genetic identification of eggs from four species of Ophichthidae and Congridae (Anguilliformes) in the northern East China Sea. PLoS One. 2018; 13(4):e0195382.
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First Record of Aedes (Stegomyia) malayensis Colless (Diptera: Culicidae) in the Lao People's Democratic Republic, Based on Morphological Diagnosis and Molecular Analysis. US Army Med Dep J. 2018 Jan-Jun; (1-18):1-7.
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Immunometabolic Determinants of Chemoradiotherapy Response and Survival in Head and Neck Squamous Cell Carcinoma. Am J Pathol. 2018 01; 188(1):72-83.
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Physiological levels of formate activate mitochondrial superoxide/hydrogen peroxide release from mouse liver mitochondria. FEBS Lett. 2017 08; 591(16):2426-2438.
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Sex differences in hippocampal damage, cognitive impairment, and trophic factor expression in an animal model of an alcohol use disorder. Brain Struct Funct. 2018 Jan; 223(1):195-210.