"Macrophage-1 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b ANTIGEN and the beta subunit the CD18 ANTIGEN. The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions.
| Descriptor ID |
D016177
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| MeSH Number(s) |
D12.776.543.750.705.408.495.500 D12.776.543.750.705.408.600.500 D12.776.543.750.705.833.500
|
| Concept/Terms |
Macrophage-1 Antigen- Macrophage-1 Antigen
- Antigen, Macrophage-1
- Macrophage 1 Antigen
- CR3 Receptor
- Receptor, CR3
- Mo1 Antigen Receptor
- Antigen Receptor, Mo1
- Receptor, Mo1 Antigen
- Mo1 Glycoprotein Receptor
- Glycoprotein Receptor, Mo1
- Receptor, Mo1 Glycoprotein
- Integrin alpha(M)beta(2)
- Integrin alpha-M beta-2
- Integrin alpha M beta 2
- alpha-M beta-2, Integrin
- Complement 3 Receptor
- Receptor, Complement 3
- Mac-1 Antigen
- Mac 1 Antigen
- Adhesive Receptor Mac-1
- Mac-1 Adhesive Receptor
- Adhesive Receptor, Mac-1
- Mac 1 Adhesive Receptor
- Receptor, Mac-1 Adhesive
- Mac-1 Receptor
- Mac 1 Receptor
- Integrin alphaMbeta2
- alphaMbeta2, Integrin
|
Below are MeSH descriptors whose meaning is more general than "Macrophage-1 Antigen".
Below are MeSH descriptors whose meaning is more specific than "Macrophage-1 Antigen".
This graph shows the total number of publications written about "Macrophage-1 Antigen" by people in this website by year, and whether "Macrophage-1 Antigen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 |
| 1999 | 1 | 1 | 2 |
| 2000 | 2 | 1 | 3 |
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2008 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Macrophage-1 Antigen" by people in Profiles.
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Dual role of the leukocyte integrin aM?2 in angiogenesis. J Immunol. 2014 Nov 01; 193(9):4712-21.
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Expression, activation, and function of integrin alphaMbeta2 (Mac-1) on neutrophil-derived microparticles. Blood. 2008 Sep 15; 112(6):2327-35.
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Manifestations of inflammatory arthritis are critically dependent on LFA-1. J Immunol. 2005 Mar 15; 174(6):3668-75.
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X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection. J Mol Biol. 2005 Feb 25; 346(3):801-14.
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Integrin engagement regulates monocyte differentiation through the forkhead transcription factor Foxp1. J Clin Invest. 2004 Aug; 114(3):408-18.
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Platelet-monocyte complex formation: effect of blocking PSGL-1 alone, and in combination with alphaIIbbeta3 and alphaMbeta2, in coronary stenting. Thromb Res. 2003; 111(3):171-7.
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Soluble adhesion molecules and the search for biomarkers for atherosclerosis. Circulation. 2002 Aug 13; 106(7):766-7.
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Antidisialoganglioside/granulocyte macrophage-colony-stimulating factor fusion protein facilitates neutrophil antibody-dependent cellular cytotoxicity and depends on FcgammaRII (CD32) and Mac-1 (CD11b/CD18) for enhanced effector cell adhesion and azurophil granule exocytosis. Blood. 2002 Jun 01; 99(11):4166-73.
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The role of Mac-1 (CD11b/CD18) in antigen-induced airway eosinophilia in mice. Am J Respir Cell Mol Biol. 2001 Aug; 25(2):170-7.
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The differential roles of LFA-1 and Mac-1 in host defense against systemic infection with Streptococcus pneumoniae. J Immunol. 2001 Jun 15; 166(12):7362-9.