Membrane Cofactor Protein
"Membrane Cofactor Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed complement receptor that binds COMPLEMENT C3B and COMPLEMENT C4B and serves as a co-factor for their inactivation by COMPLEMENT FACTOR I. It also interacts with a wide variety of pathogens and mediates the immune response.
| Descriptor ID |
D051916
|
| MeSH Number(s) |
D12.776.124.486.274.920.124 D12.776.543.750.705.833.124
|
| Concept/Terms |
Membrane Cofactor Protein- Membrane Cofactor Protein
- CD46 Antigens
- Antigens, CD46
- CD46 Antigen
- Antigen, CD46
- Trophoblast-Leukocyte Common Antigen
- Common Antigen, Trophoblast-Leukocyte
- Trophoblast Leukocyte Common Antigen
|
Below are MeSH descriptors whose meaning is more general than "Membrane Cofactor Protein".
Below are MeSH descriptors whose meaning is more specific than "Membrane Cofactor Protein".
This graph shows the total number of publications written about "Membrane Cofactor Protein" by people in this website by year, and whether "Membrane Cofactor Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 2 | 1 | 3 |
| 2014 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Membrane Cofactor Protein" by people in Profiles.
-
Common variants of fetal and maternal complement genes in preeclampsia: pregnancy specific complotype. Sci Rep. 2020 03 16; 10(1):4811.
-
Anti-Neu5Gc and anti-non-Neu5Gc antibodies in healthy humans. PLoS One. 2017; 12(7):e0180768.
-
Expression of a Synthetic Gene of CTDM by Transgenic Animals. Transplant Proc. 2016 May; 48(4):1279-81.
-
Spontaneous abortion is associated with elevated systemic C5a and reduced mRNA of complement inhibitory proteins in placenta. Clin Exp Immunol. 2014 Sep; 177(3):743-9.
-
The complement regulator CD46 is bactericidal to Helicobacter pylori and blocks urease activity. Gastroenterology. 2011 Sep; 141(3):918-28.
-
CD46 protects against chronic obstructive pulmonary disease. PLoS One. 2011 May 06; 6(5):e18785.
-
Engineered measles virus as a novel oncolytic viral therapy system for hepatocellular carcinoma. Hepatology. 2006 Dec; 44(6):1465-77.
-
Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome. Mol Immunol. 2007 Jan; 44(1-3):111-22.
-
Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome. J Am Soc Nephrol. 2006 Jul; 17(7):2017-25.
-
Hemolytic uremic syndrome: an example of insufficient complement regulation on self-tissue. Ann N Y Acad Sci. 2005 Nov; 1056:144-52.