Membrane Cofactor Protein
"Membrane Cofactor Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed complement receptor that binds COMPLEMENT C3B and COMPLEMENT C4B and serves as a co-factor for their inactivation by COMPLEMENT FACTOR I. It also interacts with a wide variety of pathogens and mediates the immune response.
| Descriptor ID |
D051916
|
| MeSH Number(s) |
D12.776.124.486.274.920.124 D12.776.543.750.705.833.124
|
| Concept/Terms |
Membrane Cofactor Protein- Membrane Cofactor Protein
- CD46 Antigens
- Antigens, CD46
- CD46 Antigen
- Antigen, CD46
- Trophoblast-Leukocyte Common Antigen
- Common Antigen, Trophoblast-Leukocyte
- Trophoblast Leukocyte Common Antigen
|
Below are MeSH descriptors whose meaning is more general than "Membrane Cofactor Protein".
Below are MeSH descriptors whose meaning is more specific than "Membrane Cofactor Protein".
This graph shows the total number of publications written about "Membrane Cofactor Protein" by people in this website by year, and whether "Membrane Cofactor Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 2 | 0 | 2 |
| 2014 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Membrane Cofactor Protein" by people in Profiles.
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Anti-Neu5Gc and anti-non-Neu5Gc antibodies in healthy humans. PLoS One. 2017; 12(7):e0180768.
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Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome. Mol Immunol. 2007 Jan; 44(1-3):111-22.
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Hemolytic uremic syndrome: an example of insufficient complement regulation on self-tissue. Ann N Y Acad Sci. 2005 Nov; 1056:144-52.
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Selectively receptor-blind measles viruses: Identification of residues necessary for SLAM- or CD46-induced fusion and their localization on a new hemagglutinin structural model. J Virol. 2004 Jan; 78(1):302-13.
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Reoxygenation of hypoxic human umbilical vein endothelial cells activates the classic complement pathway. Circulation. 1997 Jul 01; 96(1):326-33.