Phosphatidylinositol 4,5-Diphosphate
"Phosphatidylinositol 4,5-Diphosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994)
| Descriptor ID |
D019269
|
| MeSH Number(s) |
D10.570.755.375.760.400.942.625.900
|
| Concept/Terms |
Phosphatidylinositol 4,5-Diphosphate- Phosphatidylinositol 4,5-Diphosphate
- 4,5-Diphosphate, Phosphatidylinositol
- Phosphatidylinositol 4,5 Diphosphate
- Phosphatidylinositol Phosphate, PtdIns(4,5)P2
- PtIns 4,5-P2
- PtdIns(4,5)P2
- PtdInsP
- PtdInsP2
- Phosphatidylinositol 4,5-Biphosphate
- 4,5-Biphosphate, Phosphatidylinositol
- Phosphatidylinositol 4,5 Biphosphate
- Phosphatidylinositol-4,5-Biphosphate
|
Below are MeSH descriptors whose meaning is more general than "Phosphatidylinositol 4,5-Diphosphate".
Below are MeSH descriptors whose meaning is more specific than "Phosphatidylinositol 4,5-Diphosphate".
This graph shows the total number of publications written about "Phosphatidylinositol 4,5-Diphosphate" by people in this website by year, and whether "Phosphatidylinositol 4,5-Diphosphate" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Phosphatidylinositol 4,5-Diphosphate" by people in Profiles.
-
KCNQ channel PIP2 modulation: Two loose links, three rings, and a twist. Neuron. 2022 01 19; 110(2):178-180.
-
Structural insights into GIRK2 channel modulation by cholesterol and PIP2. Cell Rep. 2021 08 24; 36(8):109619.
-
Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL. Nat Cell Biol. 2016 08; 18(8):839-850.
-
Type I phosphatidylinositol phosphate kinase beta regulates focal adhesion disassembly by promoting beta1 integrin endocytosis. Mol Cell Biol. 2010 Sep; 30(18):4463-79.
-
The fellowships of the INGs. J Cell Biochem. 2005 Dec 15; 96(6):1127-36.
-
Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway. J Cell Biol. 2004 Sep 27; 166(7):1041-54.
-
von Willebrand factor binding to platelet glycoprotein Ib-IX-V stimulates the assembly of an alpha-actinin-based signaling complex. J Thromb Haemost. 2004 Jan; 2(1):161-9.
-
Enhancement of phototransduction g protein-effector interactions by phosphoinositides. J Biol Chem. 2004 Mar 05; 279(10):8986-90.
-
BTK regulates PtdIns-4,5-P2 synthesis: importance for calcium signaling and PI3K activity. Immunity. 2003 Nov; 19(5):669-78.
-
Do phosphatidylinositides modulate vertebrate phototransduction? J Neurosci. 2000 Apr 15; 20(8):2792-9.