"KCNQ3 Potassium Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A very slow opening and closing voltage-gated potassium channel that is expressed in NEURONS and is closely related to KCNQ2 POTASSIUM CHANNEL. It is commonly mutated in BENIGN FAMILIAL NEONATAL CONVULSIONS.
| Descriptor ID |
D051659
|
| MeSH Number(s) |
D12.776.157.530.400.600.900.124.249.875 D12.776.543.550.450.750.900.124.249.875 D12.776.543.585.400.750.900.124.249.875
|
| Concept/Terms |
KCNQ3 Potassium Channel- KCNQ3 Potassium Channel
- Potassium Channel, KCNQ3
- Kv7.3 Potassium Channel
- Potassium Channel, Kv7.3
- Voltage-Gated K+ Channel KCNQ3
- Voltage Gated K+ Channel KCNQ3
- KCNQ3 Protein
|
Below are MeSH descriptors whose meaning is more general than "KCNQ3 Potassium Channel".
Below are MeSH descriptors whose meaning is more specific than "KCNQ3 Potassium Channel".
This graph shows the total number of publications written about "KCNQ3 Potassium Channel" by people in this website by year, and whether "KCNQ3 Potassium Channel" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "KCNQ3 Potassium Channel" by people in Profiles.
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KCNQ2/3 Gain-of-Function Variants and Cell Excitability: Differential Effects in CA1 versus L2/3 Pyramidal Neurons. J Neurosci. 2023 09 20; 43(38):6479-6494.
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Impact of the KCNQ2/3 Channel Opener Ezogabine on Reward Circuit Activity and Clinical Symptoms in Depression: Results From a Randomized Controlled Trial. Am J Psychiatry. 2021 05 01; 178(5):437-446.
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Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders. Nat Commun. 2020 10 01; 11(1):4932.
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Autism and developmental disability caused by KCNQ3 gain-of-function variants. Ann Neurol. 2019 08; 86(2):181-192.
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Deletion of KCNQ2/3 potassium channels from PV+ interneurons leads to homeostatic potentiation of excitatory transmission. Elife. 2018 11 01; 7.
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Acute stress diminishes M-current contributing to elevated activity of hypothalamic-pituitary-adrenal axis. Neuropharmacology. 2017 03 01; 114:67-76.
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An Ankyrin-G N-terminal Gate and Protein Kinase CK2 Dually Regulate Binding of Voltage-gated Sodium and KCNQ2/3 Potassium Channels. J Biol Chem. 2015 Jul 03; 290(27):16619-32.
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Cholinergic afferent stimulation induces axonal function plasticity in adult hippocampal granule cells. Neuron. 2015 Jan 21; 85(2):346-63.
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Heteromeric Kv7.2/7.3 channels differentially regulate action potential initiation and conduction in neocortical myelinated axons. J Neurosci. 2014 Mar 05; 34(10):3719-32.
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Axonal Kv7.2/7.3 channels: caught in the act. Channels (Austin). 2014; 8(4):288-9.