"KCNQ Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of delayed rectifier voltage-gated potassium channels that share homology with their founding member, KCNQ1 PROTEIN. KCNQ potassium channels have been implicated in a variety of diseases including LONG QT SYNDROME; DEAFNESS; and EPILEPSY.
Descriptor ID |
D051656
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MeSH Number(s) |
D12.776.157.530.400.600.900.124.249 D12.776.543.550.450.750.900.124.249 D12.776.543.585.400.750.900.124.249
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Concept/Terms |
KCNQ Potassium Channels- KCNQ Potassium Channels
- Potassium Channels, KCNQ
- KvLQT Potassium Channels
- Potassium Channels, KvLQT
|
Below are MeSH descriptors whose meaning is more general than "KCNQ Potassium Channels".
Below are MeSH descriptors whose meaning is more specific than "KCNQ Potassium Channels".
This graph shows the total number of publications written about "KCNQ Potassium Channels" by people in this website by year, and whether "KCNQ Potassium Channels" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "KCNQ Potassium Channels" by people in Profiles.
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Acute stress diminishes M-current contributing to elevated activity of hypothalamic-pituitary-adrenal axis. Neuropharmacology. 2017 03 01; 114:67-76.
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Hyper-SUMOylation of the Kv7 potassium channel diminishes the M-current leading to seizures and sudden death. Neuron. 2014 Sep 03; 83(5):1159-71.
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Transcompartmental reversal of single fibre hyperexcitability in juxtaparanodal Kv1.1-deficient vagus nerve axons by activation of nodal KCNQ channels. J Physiol. 2012 Aug 15; 590(16):3913-26.
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A KCNQ channel opener for experimental neonatal seizures and status epilepticus. Ann Neurol. 2009 Mar; 65(3):326-36.
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Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons. Proc Natl Acad Sci U S A. 2008 Jun 03; 105(22):7869-74.
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Mutation of colocalized residues of the pore helix and transmembrane segments S5 and S6 disrupt deactivation and modify inactivation of KCNQ1 K+ channels. J Physiol. 2005 Mar 01; 563(Pt 2):359-68.
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A-type voltage-gated K+ currents influence firing properties of isolectin B4-positive but not isolectin B4-negative primary sensory neurons. J Neurophysiol. 2005 Jun; 93(6):3401-9.
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Compound mutations: a common cause of severe long-QT syndrome. Circulation. 2004 Apr 20; 109(15):1834-41.
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M-channels: neurological diseases, neuromodulation, and drug development. Arch Neurol. 2003 Apr; 60(4):496-500.
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Low frequency of p57KIP2 mutation in Beckwith-Wiedemann syndrome. Am J Hum Genet. 1997 Aug; 61(2):304-9.